<div>Mulching films used in agriculture gradually break down and can become a significant source of microplastics in soils. A new study shows that these particles affect not only soil structure but also microbial life and nitrogen cycling.“We wanted to understand how microplastics from both conventional and biodegradable mulching films influence soil properties, microbial diversity and functions in real conditions,” explains Klára Šmídová, the study’s co-author . “That’s why we added realistic amounts of microplastics to soils in experimental plots in Finland, Germany, and Spain, monitored them over two growing seasons, and compared them with the control plots.”The results revealed that microplastics alter soil characteristics and microbial communities, although not always in the same way. “ However, a consistent finding was the decline in microbial activity associated with key processes, including nitrogen cycling, with negative effects increasing at higher microplastic concentrations and becoming more pronounced in the second year,” Šmídová adds. Because the microplastic levels used in the study reflect amounts already found in European soils, the findings highlight real risks to soil health. “We also found that the effects were stronger in southern than in northern Europe, likely due to differences in climate and soil conditions. This means that protecting soils from plastic pollution will require region-specific risk assessments,” she says.Over 60% of European soils are estimated to be unhealthy, with ongoing degradation driven by unsustainable land use, contamination, climate change, and extreme weather events. In response, the EU Parliament adopted the Soil Monitoring Law in October 2025, aiming to achieve healthy soils across Europe by 2050. “The law highlights the role of soil health in food security, water quality, and climate objectives, and establishes consistent soil monitoring across Member States. It includes measures to support farmers and foresters, while also creating a public list of potentially contaminated sites and an indicative watch list of emerging soil contaminants,” explains Klára Šmídová.The project brought together 19 research groups across Europe. “After each season, hundreds of samples were colle cted and sent to partners for analysis. This paper focuses on soil properties, microbial diversity, and greenhouse gas emissions. Two more manuscripts—on plastic additives and microplastic fate, and on soil invertebrates—are in preparation. Together, they will give us a complete picture of how agricultural microplastics affect soil ecosystems,” concludes Klára Šmídová.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/RECETOX_Vysledky_nove_studie_ukazaly_ze_mikroplasty_meni_vlastnosti_pudy_a_mikrobialni_spolecenstva_i_v_realnych_podminkach_6ee3413a7b.jpg" alt="RECETOX: New Study Reveals How Agricultural Plastics Impact Soil Health In Real Conditions" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_RECETOX_Vysledky_nove_studie_ukazaly_ze_mikroplasty_meni_vlastnosti_pudy_a_mikrobialni_spolecenstva_i_v_realnych_podminkach_6ee3413a7b.jpg 171w," sizes="100vw" width="738" height="674"><blockquote><h4>The Original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S0269749125015866?via%3Dihub#sec2">Conventional and biodegradable agricultural microplastics: effects on soil properties and microbial functions across a European pedoclimatic gradient</a></h4>Šmídová K., Soinne H., Kim S. W., Tirronniemi J., Meffe R., Redondo-Hasselerharm P. E., Braun M., Rillig M. C., Fritze H., Adamczyk B., Nikama J., Kaseva J., Saartama V., Amelung W., Hurley R., Hofman J., Nizzetto L., Selonen S., Velmala S.Environ. Pollut. 386 (2025) 127212<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.envpol.2025.127212">10.1016/j.envpol.2025.127212</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4><div>Agricultural plastics like mulching films may become a major source of microplastic (MP) soil contamination during their degradation and fragmentation. This study investigates the effects of agricultural MPs from conventional (linear low-density polyethylene, PE) and biodegradable (starch-blended polybutylene adipate co-terephthalate, PBAT-BD) mulching films on soil physicochemical properties, aggregation, microbial diversity and functions, litter decomposition, and greenhouse gases emissions (GHG). For this purpose, MPs were mixed into soils at realistic MP concentrations of 0.005&nbsp;% and 0.05&nbsp;% (w/w) in 2022 on experimental plots in three EU countries representing different pedoclimatic conditions (Finland, Germany and Spain), followed by monitoring of the above-mentioned variables in the subsequent growing seasons 2022 and 2023. We found several significant MP-induced effects for soil properties, aggregation, microbial diversity, litter decomposition, and GHG, but the effect endpoints were less pronounced or varied considerably. Contrarily, microbial activity, contributing to soil functions such as nitrogen cycling, was consistently reduced by both conventional and biodegradable MPs. The reductions were more pronounced after the second season and for the higher MP treatment. As the higher MP concentration (i.e., 0.05&nbsp;% w/w) is environmentally relevant in Europe, our findings emphasize the potential effects of environmentally relevant MP concentrations on soil health. Furthermore, the effects increased from north to south, probably modulated by varying pedoclimatic conditions, inducing reflection of a need for regionally tailored risk</div></div>

New Study Reveals How Agricultural Plastics Impact Soil Health In Real Conditions

<h3>Charged for Action: The Hidden Secrets of AEX Oligonucleotide Analysis</h3>Oligonucleotides—short, well-defined fragments of DNA or RNA—have become indispensable tools in modern life sciences. They underpin cutting-edge applications in molecular diagnostics, gene therapy, and pharmaceutical development. Before oligonucleotides can be confidently used in research or clinical settings, however, their quality must be rigorously assessed. Purity, sequence integrity, length distribution, and chemical modifications all play a decisive role in their performance.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Oligos_Made_Easy_Part_2_AEX_2_45eee54fa0.jpg" alt="KNAUER: Oligos Made Easy - Part 2: AEX" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Oligos_Made_Easy_Part_2_AEX_2_45eee54fa0.jpg 245w," sizes="100vw" width="1534" height="711">Among the analytical techniques available today, anion exchange chromatography (AEX) stands out as a robust and highly informative method for characterizing oligonucleotides. By exploiting their intrinsic negative charge, AEX provides detailed insight into product composition and impurity profiles that are difficult to obtain by other approaches.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6808">Part 1 of the Oligos series: A Practical Guide to Oligonucleotide Production – From Concept to Final Product</a></blockquote><h4>How Scientists Read Oligonucleotides Using Charge</h4>At the core of AEX lies a simple but powerful principle: oligonucleotides carry a negatively charged phosphate backbone. This charge increases in a predictable way with strand length and, to a lesser extent, sequence composition. Anion exchange chromatography uses this property to separate oligonucleotides based on differences in charge strength and interaction with a positively charged stationary phase.As a result, AEX has become one of the most widely used analytical tools for evaluating oligonucleotide quality. It allows scientists to distinguish full-length products from truncated species, degradation products, or closely related variants—often with single-nucleotide resolution.<h4>Why Ion Exchange Works: Binding, Retention, and Release</h4>Ion exchange chromatography (IEX) relies on electrostatic interactions between analytes and a charged stationary phase. In the case of oligonucleotides, anion exchange is used, where negatively charged molecules interact with positively charged functional groups on the resin—most commonly quaternary amines.The system consists of two main components:<ul><li>Stationary phase: A positively charged resin that binds anionic analytes.</li><li>Mobile phase: An aqueous buffer system, typically combined with a salt gradient, that controls both pH and elution strength.</li></ul>Retention in AEX is governed primarily by charge. Molecules with weaker overall charge interact less strongly with the stationary phase and elute earlier, while more highly charged oligonucleotides bind more tightly and require stronger elution conditions.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_1_IEX_overview_including_elution_order_dependency_on_analyte_charge_3419ad3075.jpg" alt="KNAUER: Oligos Made Easy - Part 2 AEX: Figure 1 IEX overview including elution order dependency on analyte charge." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_1_IEX_overview_including_elution_order_dependency_on_analyte_charge_3419ad3075.jpg 245w," sizes="100vw" width="1583" height="654"><h4>The Five-Step Workflow of Ion Exchange Chromatography</h4>AEX separations generally follow a well-established sequence of steps:<ol><li>Column equilibration The column is conditioned with the starting buffer until the baseline and pH are stable. This ensures that all charged sites on the resin are ready for interaction.</li><li>Sample loading Samples, prepared in the starting buffer, are introduced under conditions that promote binding of the target oligonucleotides while minimizing retention of unwanted impurities.</li><li>Washing The column is washed with the starting buffer to remove uncharged or weakly interacting components. The baseline stabilizes as these species are flushed away.</li><li>Elution Bound oligonucleotides are released using a salt or pH gradient. Increasing ionic strength introduces competing ions that displace the analytes from the resin. Weakly bound species elute first; strongly charged oligonucleotides elute later.</li><li>Regeneration and re-equilibration A high-salt buffer removes any remaining bound material. The column is then returned to starting conditions in preparation for the next analysis.</li></ol><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_2_Five_steps_of_IEX_procedure_in_blue_outlined_using_an_example_chromatogram_in_red_38dd70b1b1.jpg" alt="KNAUER: Oligos Made Easy - Part 2 AEX: Figure 2 Five steps of IEX procedure (in blue), outlined using an example chromatogram (in red)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_2_Five_steps_of_IEX_procedure_in_blue_outlined_using_an_example_chromatogram_in_red_38dd70b1b1.jpg 245w," sizes="100vw" width="1583" height="674"><h4>Why AEX Is Especially Effective for Oligonucleotides</h4>The repeating phosphate backbone of oligonucleotides gives rise to a strong and uniform anionic character across a wide pH range (typically pH 7–9). This makes oligonucleotides exceptionally well suited for anion exchange separations.Key factors influencing AEX behavior include:<ul><li>Charge density: Longer oligonucleotides carry more negative charges and therefore exhibit stronger retention.</li><li>Resin chemistry: Strong and weak anion exchangers differ in functional groups and pH stability, influencing selectivity and robustness.</li><li>Buffer composition: The choice of buffering ions and salt gradients directly affects elution strength and resolution.</li></ul>Salt gradients—commonly based on chloride ions—compete with the oligonucleotide backbone for binding sites on the resin. By carefully tuning gradient slope and composition, analysts can achieve highly reproducible and finely resolved separations.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_3_Ionic_interactions_and_p_H_influence_on_Anion_Exchange_Chromatography_AEX_612e231ba4.jpg" alt="KNAUER: Oligos Made Easy - Part 2 AEX: Figure 3 Ionic interactions and pH influence on Anion Exchange Chromatography (AEX)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_3_Ionic_interactions_and_p_H_influence_on_Anion_Exchange_Chromatography_AEX_612e231ba4.jpg 245w," sizes="100vw" width="1547" height="593"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_4_AEX_buffer_selection_and_gradient_strategy_chromatogram_with_red_buffer_gradient_curve_53fd1bb11b.jpg" alt="KNAUER: Oligos Made Easy - Part 2 AEX: Figure 4 AEX buffer selection and gradient strategy (chromatogram with red buffer gradient curve)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_4_AEX_buffer_selection_and_gradient_strategy_chromatogram_with_red_buffer_gradient_curve_53fd1bb11b.jpg 245w," sizes="100vw" width="1600" height="327"><h4>AEX as the Gold Standard for Oligonucleotide Separation</h4>Anion exchange chromatography has become the method of choice for both analytical and preparative oligonucleotide workflows. Its advantages include:<ul><li>High resolving power: Closely related impurities, including n–1 or n–2 species, can often be separated and quantified.</li><li>Predictable retention behavior: In many cases, retention time correlates linearly with oligonucleotide length, simplifying identification.</li><li>Compatibility with modified oligonucleotides: Even chemically modified sequences retain their anionic nature, allowing AEX to resolve both products and related impurities.</li><li>Excellent control via gradient elution: Salt gradients provide precise tuning of selectivity and resolution.</li></ul>Typically, shorter or degraded oligonucleotides elute at lower ionic strength, while full-length products with higher charge density appear later in the chromatogram.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_5_AEX_Advantages_and_Challenges_7835521e34.jpg" alt="KNAUER: Oligos Made Easy - Part 2 AEX: Figure 5 AEX Advantages and Challenges." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Oligos_Made_Easy_Part_2_AEX_Figure_5_AEX_Advantages_and_Challenges_7835521e34.jpg 245w," sizes="100vw" width="1535" height="707"><h4>Final Perspective: Mastering AEX with Confidence</h4>Anion exchange chromatography may appear complex at first, but with thoughtful optimization of pH, buffer composition, and gradient conditions, it becomes a highly precise and reliable tool for oligonucleotide analysis. When properly applied, AEX delivers sharp peaks, excellent resolution, and robust performance—even for challenging sequences and modifications.For laboratories developing or refining oligonucleotide workflows, AEX offers both analytical depth and operational confidence.<blockquote>If you would like to discuss AEX method development or optimization for oligonucleotides, feel free to contact us at sales@knauer.net. More insights into practical oligonucleotide analysis will follow in our “Oligos Made Easy” series.For technical questions or in-depth discussion, the author can be reached at kindler@knauer.net</blockquote>

Oligos Made Easy - Part 2: AEX

News from LabRulezLCMS Library - Week 07, 2026

Article

Application

Plastics

Environment

Science and research

Poster

RECETOX (Research Centre for Toxic Compounds in the Environment) is an independent department of the Faculty of Science of Masaryk University in Brno, which has been established in 1983. RECETOX is focused on the research and education in cross-cutting area of Environment and Health. It addresses interactions among chemicals, environment, and biological systems, including consequences at local, regional, and global levels.

RECETOX - Centrum pro výzkum toxických látek v prostředí

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Based in Berlin, KNAUER is a medium-sized, owner-managed company that has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography, including: Analytical HPLC/UHPLC, Preparative HPLC, Fast protein liquid chromatography (FPLC), Multi-column chromatography/Simulated moving bed (SMB) chromatography. High pressure dosing, in-line detection systems, and osmometry are additional business areas.

KNAUER

SIELC Alltesta Mini HPLC Autosampler

The Alltesta™ Mini Autosampler is an affordable and dependable solution for automated sample handling in various analytical and liquid handling applications, including HPLC.

The Alltesta™ Mini Autosampler is an affordable and dependable solution for automated sample handling in various analytical and liquid handling applications, including HPLC. With its proprietary alpha/beta mechanical design, this compact autosampler offers direct and comprehensive control of its features, making integration quick and easy. Users can tailor the mini autosampler to their needs with customizable valve configurations, tray designs, and syringe volumes and pressures. Additionally, a built-in shaking feature enables sample mixing before injection and/or simple sample extraction within the vial.
This compact autosampler comes designed with original equipment manufacturer (OEM) customization in mind. Custom shape, color, and communication interfaces can be adapted to integrate with any system. Comprehensive software integration support is provided. Other options include metal-free sampling and reagent addition and mixing capabilities.
<ul>
<li>FRACTION COLLECTION CAPABILITY: A simple software modification can quickly convert this small autosampler into a fraction collector.
</li>
<li>REACTOR PROBE SAMPLER CAPABILITY: A simple software modification can quickly convert this small autosampler into a reactor probe sampler.
</li>
</ul>
This miniature autosampler can also be used as a component of our <a href="https://lcms.labrulez.com/products/1242">Alltesta™ Gradient Automated Analyzer</a> and <a href="https://lcms.labrulez.com/products/1243">Alltesta™ Cromite Analyzer</a>.
<blockquote>
<h4>The price of the Alltesta™ Mini Autosampler varies depending on the specific configuration requested.</h4>
</blockquote>
<h4>Specifications</h4>
<ul>
<li>Dimensions (WHL): 160 x 145 x 195 mm / 6.3 x 5.71 x 7.68 in</li>
<li>Weight: 3 kg / 6.6 lb</li>
<li>Power: 24 V</li>
<li>Capacity: 48 vials or 96-well plate</li>
<li>Pressure: 5000 psi</li>
<li>Needle Wash: Inside and outside</li>
<li>Syringe Capacity: 120µL high-pressure / 4000µL low-pressure stainless / 4000µL low-pressure ceramic</li>
<li>Valve options: 6×2, 7×6 and 10×9 (more details here).</li>
<li>Volume Accuracy: 0.1µL</li>
<li>Communication: RS232 Virtual COM port via USB</li>
</ul>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SIELC_Alltesta_Mini_Autosampler_A_very_simple_schematic_operation_of_the_Alltesta_Autosampler_b79b0ad187.jpg" alt="SIELC: Alltesta™ Mini Autosampler - A very simple schematic operation of the Alltesta™ Autosampler."/>
<h4>Software</h4>
The Alltesta™ Autosampler can be controlled:
<ul>
<li>directly via serial commands (Alltesta™ protocol available upon request, please contact us at support@sielc.com),</li>
<li>directly via our demo software, allowing to learn the whole functionality of the unit (<a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Autosampler_Control_Windows_10.zip">Windows 10, 32/64bit</a>, 5Mb; <a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Autosampler_Control_Windows_7.zip">Windows 7, 32/64bit</a>, 126Mb).</li>
<li>remotely through our cloud software (as a part of Alltesta™ Analyzer or Alltesta™ Mini Analyzer),</li>
</ul>
Serial communication drivers are available <a href="https://ftdichip.com/drivers/vcp-drivers/">here</a>.

SIELC Alltesta™ Mini LHS (Liquid Handling Station)

The Alltesta™ Mini Liquid Handling Station serves as an affordable, reliable solution for automated sample handling.

The Alltesta™ Mini Liquid Handling Station serves as an affordable, reliable solution for automated sample handling. With its compact design, proprietary alpha/beta mechanical structure, and adjustable operation speeds, it offers comprehensive control for quick and seamless integration with other equipment. The station comes equipped with a built-in sample shaking feature for in-vial sample mixing and extraction, and a needle washing station capable of accommodating up to four solvents.
Designed with Original Equipment Manufacturer (OEM) customization in mind, the Alltesta™ Mini Liquid Handling Station can be tailored to fit any system’s requirements. Custom needle lengths and trays enable the device to accommodate various types of vials. An array of integrated valves and a measuring syringe can be added to the device. Additional customization options, such as metal-free flow paths and customer-specified enclosure colors, are also available.
Comprehensive software integration support is provided to ensure smooth operation and functionality.
<h4>Specifications</h4>
<ul>
<li>Dimensions (WHL): 160 x 145 x 195 mm / 6.3 x 5.71 x 7.68 in</li>
<li>Weight: 2.25 kg / 5 lb</li>
<li>Power: 24 V</li>
<li>Capacity: 48-vial tray or 96-well plate</li>
<li>Needle Wash: Inside and Outside</li>
<li>Communication: RS232 Virtual COM port via USB</li>
</ul>
<h4>Software</h4>
The Alltesta™ LHS can be fully controlled via serial commands. Alltesta™ protocol available upon request, please contact us at support@sielc.com. Serial communication drivers are available <a href="https://ftdichip.com/drivers/vcp-drivers/">here</a>.

SIELC Samplify Automated sampling system

Samplify Is a device which allows unattended sampling of a reaction mixture or bioprocess or continue in line flow by taking small amount of liquid from the monitoring mixture and collecting it in a vial or a 96 wells plate

Samplify™ Is a device which allows unattended sampling of a reaction mixture or bioprocess or continue in line flow by taking small amount of liquid from the monitoring mixture and collecting it in a vial or a 96 wells plate. It also allows to dilute the sample with assigned dilution ratio and can provide reaction quenching to preserve the sample state at time of sampling. It has two main components: an autosampler and a probe. The Samplify™ &nbsp;controlled and setup by a PC software.<h3>Description</h3>It is a common task in the lab to periodically sample a reactor or a fermenter to obtain information about reaction kinetic, completion and have a tangible representation of intermediate states of a dynamic process. This usually done manually with pipettes or syringes, using stopwatch to measure time and requires to be in the lab during the entire process.With Samplify it can be done in automated mode. When an automated sampling process is used it increases accuracy, safety, and productivity. It reduces potential samples cross contamination, and exposure of the reaction mixture to oxygen or moisture, when anaerobic or moisture free conditions are required.<ul><li>Based on a proprietary alpha/beta mechanical configuration, Alltesta Miniature Autosampler and patent pending sample probe offers affordable and reliable automation for many analytical and liquid-handling applications.&nbsp;</li><li>Small controllable volume of sample can be programmed and precisely removed from the enclosed or open system. The sample will then be transferred to a vial with inert solvent with measured volume to create a controllable dilution factor.</li><li>A quench solution can be automatically preloaded in each vial to provide termination of reaction or biological process, and preserve sample content in the time of probing.</li><li>In order to effectively mix samples with diluents or quenching reagents a shaking capability of the autosampler tray can be initiated after each sample cycle.</li><li>PC based software allows quick, but flexible, setup of the sampling experiment. Several preloaded methods can be quickly adapted to a particular needs of the user.</li><li>For temperature sensitive samples the entire autosampler can be placed in the temperature controlled environment.</li><li>The device small size allow to place it close to the reactor and use short connection lines to minimize dispersion. Also a small cooler can be used to keep samples in cold conditions after they are collected.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SIELC_SIELC_Samplify_Automated_sampling_system_937b70e8d2.jpg" alt="SIELC: SIELC Samplify™ Automated sampling system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_SIELC_SIELC_Samplify_Automated_sampling_system_937b70e8d2.jpg 245w," sizes="100vw" width="1346" height="663"><h3>Specifications</h3><h4>Samplify™ Autosampler:</h4><ul><li>Syringe volume: 4.0 mL</li><li>Pressure: up to 250 psi</li><li>Valve configuration: 7×6</li><li>Power Requirements: 24 VDC</li><li>Current Requirements: Up to 1.0 A</li><li>Dimensions (WHL): 160 x 145 x 195 mm / 6.3 x 5.71 x 7.68 in</li><li>Weight: &nbsp;3 kg / 6.6 lb</li><li>Inlets/Outlets: Thread 10-32 UNF compression type</li><li>Materials in contact with liquid: SS316, PTFE, PEEK</li><li>Tray capacity: 48 vials 1.8 mL volume or 96 wells plate</li><li>Communication: USB virtual serial port</li></ul><h4>Samplify™ Probe:</h4><ul><li>Connection: requires Alltesta-Samplify autosampler</li><li>Dimensions: 1 x 1 inch, DIA ¼ inch. Immersion length up to 6 inch</li><li>Materials in contact with liquid: Stainless Steel 316 (316L), PEEK &amp; PTFE</li><li>Variable sample volume: from 5 to 500 µL</li><li>Max. working pressure: 120 psi (8 bar)</li><li>Max. working temperature: &nbsp;200 °C</li></ul><h3>Software</h3>The Samplify can be controlled:<ul><li>directly through your software via serial commands (Alltesta™ protocol available upon request, please contact us at support@sielc.com),</li><li>remotely through our cloud software (autosampler.cloud),</li><li>directly via our Samplify PC software, allowing to fully control all the parameters of the sampling operations</li></ul><h3>Available Custom Options</h3>Metal-free version of the syringe pump includes no metal contact pump head.

Organomation ROT-X-TRACT-S Soxhlet extractor

Unlike traditional wire or sand baths which are used to heat receiving flasks, the ROT-X-TRACT-S uses a water steam bath which provides gentle even heat to delicate samples.

Soxhlet extraction is ideal for extracting soluble analytes from a solid sample into an organic solvent. Unlike traditional wire or sand baths which are used to heat receiving flasks, the ROT-X-TRACT-S uses a water steam bath which provides gentle even heat to delicate samples.The ROT-X-TRACT-S rotary Soxhlet extractors can accommodate up to 8 or 10 Soxhlet extractors. The bath cover disc holes can accommodate round sample flasks from 125 ml-1 L. Models 13070 and 13090 can accommodate smaller 250 mL flasks, while model 13008 can accommodate larger 500 mL flasks. A wide range of sample sizes and quantities make this instrument ideal for Soxhlet extraction of samples in any lab.<h4>Standard features</h4><ul><li>Stainless steel construction</li><li>Stepped bath rim and cover disk seals steam chamber</li><li>Each condenser water line attached to centrally located water manifold</li><li>Laboratory grade materials stand up to organic solvents</li></ul><h4>OPTIONS (Add to main Cat# when purchasing)</h4><ul><li>Positive pressure type Z purged bath (Option Code -Z), Cat# 13070/13090/13008-Z</li><li>240V wiring and plug (Option Code -2), Cat# 13070/13090/13008-2</li></ul><h4>ACCESSORIES</h4><ul><li>P1332: O-rings for S-EVAP/RXT water manifold</li><li>All associated glassware</li><li>Rotary clamp manifold assembly</li><li>Bath cover disks</li></ul><h4>Specification</h4><h5>Model 13070 – 8 Position, 37 mm Extractors</h5>Ideal for labs using 250 mL round-bottom flasks, this model features a medium-size 12-inch ID water bath (Model 9125) and supports GS3137 or GS3129 glassware.<ul><li>Overall Dimensions: 18 × 16 × 34 in (46 × 41 × 86 cm)</li><li>Heating Power: 900 W</li><li>Temperature Control: Dial thermostat with ±2 °C accuracy</li></ul><h5>Model 13090 – 10 Position, 37 mm Extractors</h5>This high-throughput option also works with 250 mL flasks and uses a larger 16-inch ID bath (Model 16165) to accommodate 10 samples simultaneously.<ul><li>Overall Dimensions: 24 × 19 × 34 in (61 × 48 × 86 cm)</li><li>Heating Power: 1600 W</li><li>Temperature Control: Dial thermostat with ±2 °C accuracy</li></ul><h5>Model 13008 – 8 Position, 50 mm Extractors</h5>For larger sample volumes, Model 13008 supports 500 mL round-bottom flasks and includes a 16-inch bath with higher accuracy temperature control. It uses GS3150 glassware and larger 55/50 extractor joints for robust handling of bigger samples.<ul><li>Overall Dimensions: 24 × 19 × 37 in (61 × 48 × 94 cm)</li><li>Heating Power: 1600 W</li><li>Temperature Control: Dial thermostat with ±0.5 °C accuracy</li></ul><h5>Key Shared Features</h5><ul><li>Extractor Joint Sizes:<ul><li>13070 &amp; 13090: 45/50, 24/40</li><li>13008: 55/50, 24/40</li></ul></li><li>Condenser Options:<ul><li>Standard: Allihn</li><li>Optional: Friedrichs (for enhanced cooling performance)</li></ul></li><li>Condenser Joint Size: 55/50</li><li>Bath Temperature Range: 40–100 °C</li><li>Heating Medium: Water</li><li>Bath Inside Dimensions:<ul><li>13070: 12 × 4.5 in (30.5 × 11.4 cm)</li><li>13090 &amp; 13008: 16 × 4.5 in (40.6 × 11.4 cm)</li></ul></li></ul>

Organomation 12 Position N-EVAP Nitrogen Evaporator

The 12 position N-EVAP nitrogen evaporator is a compact unit that allows for up to 12 samples to be evaporated simultaneously.  At each individual sample position, the gas flow can be controlled via a precision needle valve.

The 12 position N-EVAP nitrogen evaporator (cat# 11155) is a compact unit that allows for up to 12 samples to be evaporated simultaneously. At each individual sample position, the gas flow can be controlled via a precision needle valve. This is ideal for the simultaneous evaporation of samples with varying evaporation end points. The sample tray has a spring tensioner which allows any test tube between 10-30 mm to be processed without any modifications to the instrument. An optional small sample holder allows samples with an outside diameter of 5-16 mm to be processed.First introduced in 1959 as The Meyer N-EVAP, the 12 position N-EVAP (cat# 11155) was the first nitrogen dryer created by Organomation. It has proven to be an extremely durable, time tested and highly affordable member of Organomation’s N-EVAP line. These economical units provide controlled concentration of sample vials through the application of nitrogen gas within a heated water bath. The N-EVAP’s circular rotating design permits each sample to be accessible from the front of the instrument for easy insertion and retrieval. The chrome plated needle valves are individually milled from solid brass, enabling precise, uniform adjustments for your nitrogen blow down. This promotes efficient and safe sample reduction with minimal nitrogen waste.<ul><li>Small Footprint: N-EVAP Model 111 requires under one square foot of bench space</li><li>Flexible: An adjustable sample holder design fits a wide variety of sample tubes and vials at once</li><li>Customizable: Options are available for use with acidic or flammable solvents, heat- or water-sensitive samples, and more</li><li>Individualized Control: Optimize evaporation of diverse samples with individual gas flow control at each vial</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_12_Position_N_EVAP_Nitrogen_Evaporator_5_339151fb9f.jpg" alt="Organomation 12 Position N-EVAP Nitrogen Evaporator ." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_12_Position_N_EVAP_Nitrogen_Evaporator_5_339151fb9f.jpg 156w," sizes="100vw" width="1400" height="1400"><h3>STANDARD FEATURES</h3><ul><li>Nitrogen filter</li><li>Adjustable flow meter, 0-10 LPM</li><li>High pressure phthalate free tubing for safety</li><li>High temperature limit switch for safety</li><li>Dual band spring hoist assembly (except in dry bath model)</li><li>Precision needle valve tube assembly</li><li>Needles, 4 inch x 19 gauge with chrome plated brass hub and stainless steel shaft</li></ul><h3>OPTIONS&nbsp;</h3><ul><li>220v wiring harness (Option Code# -2), Cat# 11155-2</li><li>Z-Purge/positive pressure purge case (Option Code# -Z), Cat# 11155-Z</li><li>Acid resistant coating on instrument and needles (Option Code# -RT), Cat# 11155-RT</li></ul><h3>SPECS</h3><h4>12p N-EVAP (Water Bath)</h4><ul><li>Bath Type: Water</li><li>Instrumental Catalog Number: 11155</li><li>Number of Sample Positions: 12</li><li>Overall Dimension (w x d x h): 13 x 11 x 31 in / 33 x 28 x 79 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 5–16 mm OD</li><li>Gas Flow Meter: 0–10 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: Dual Band Spring Hoist Assembly</li><li>Rotating, Leak Tight Gas Fitting: Standard</li><li>Standard Gas Input Range: 20–30 psig</li><li>Optional Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating (Option Code -RT): Optional</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number: 5585</li><li>Heating Medium: Water</li><li>Inside Dimensions (Diameter × Depth): 8.5 × 4.5 in / 21.6 × 11.4 cm</li><li>Outside Dimensions (w × d × h): 13 × 11 × 7 in / 33 × 28 × 18 cm</li><li>Total Wattage: 550 W</li><li>Bath Temperature Range: 30–90 °C</li><li>Temperature Controller Type: Mechanical Thermostat</li><li>Controller Accuracy: ± 2 °C</li></ul><h4>12p N-EVAP (Dry Bath)</h4><ul><li>Bath Type: Dry</li><li>Instrumental Catalog Number: 11155-DA</li><li>Number of Sample Positions: 12</li><li>Overall Dimension (w x d x h): 13 x 11 x 27.5 in / 33 x 28 x 70 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 5–16 mm OD</li><li>Gas Flow Meter: 0–10 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: None/Fixed</li><li>Rotating, Leak Tight Gas Fitting: N/A</li><li>Standard Gas Input Range: 20–30 psig</li><li>Optional Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating (Option Code -RT): Optional</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number: 5085</li><li>Heating Medium: Aluminum Beads (Glass Beads in RT Models)</li><li>Inside Dimensions (Diameter × Depth): 8.5 × 4.5 in / 21.6 × 11.4 cm</li><li>Outside Dimensions (w × d × h): 13 × 11 × 7 in / 33 × 28 × 18 cm</li><li>Total Wattage: 500 W</li><li>Bath Temperature Range: 40–130 °C</li><li>Temperature Controller Type: Mechanical Thermostat</li><li>Controller Accuracy: ± 2 °C</li></ul><h4>12p N-EVAP (No Bath)</h4><ul><li>Bath Type: None</li><li>Instrumental Catalog Number: 11155-O</li><li>Number of Sample Positions: 12</li><li>Overall Dimension (w x d x h): 12 × 8 × 31 in / 33 × 28 × 79 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 5–16 mm OD</li><li>Gas Flow Meter: 0–10 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: Dual Band Spring Hoist Assembly</li><li>Rotating, Leak Tight Gas Fitting: Standard</li><li>Standard Gas Input Range: 20–30 psig</li><li>Optional Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating (Option Code -RT): Optional</li></ul><h3>MODELS</h3><h5>Catalog Number &nbsp;/&nbsp;&nbsp;&nbsp;Bath Type</h5><ul><li>11155: Water Bath</li><li>11155-NT: No Teflon, Water Bath*</li><li>11155-DA: Dry Bath</li><li>11155-O: No Bath</li></ul>* No Teflon (-NT) units designed for PFAS analysis using EPA methods 533, 537 and 537.1. **All “-O” models come with a base and stand assembly instead of a heated bath. These instruments are designed for evaporation procedures performed at ambient temperature.<h3>ACCESSORIES</h3><ul><li>Small vessel sample holder, for vial outside diameters of 5-16 mm (cat# NA1132)</li><li>Nitrogen generator (cat# NA1955)</li><li>Pasteur pipette adapters (cat# NA0636)</li><li>Pressure reducing regulator 0-160 psi (cat# NA0630)</li><li>High temperature silicone fluid (cat# NA1240)</li><li>Various needle sizes and gauges</li></ul><h3>REPLACEMENT PARTS</h3><ul><li>P0627: Valve Tube Assembly – Post 1997</li><li>P0607: Luer &amp; washer for N-EVAP valve tube</li><li>P0634: Tube Fitting nylon 3 part for N-EVAP valve tube</li></ul>

Organomation 24 Position N-EVAP Nitrogen Evaporator

The 24 position N-EVAP is our most adaptable benchtop evaporator. The basic model offers all of the standard features from our N-EVAP line. Additionally, the 24 position N-EVAP offers the most customizable options for your sample preparation needs. 

The 24 position N-EVAP is our most adaptable benchtop evaporator. The basic model offers all of the standard features from our N-EVAP line. Additionally, the 24 position N-EVAP offers the most customizable options for your sample preparation needs. The standard sample holder can accommodate samples with an outside diameter of 10-30 mm. However, with the optional 8 position large sample holder, vials with an outside diameter of 30-70 mm can be processed. The 24 position N-EVAP test tube evaporator can also be upgraded to include digital controls for heat and time with the addition of the side control box (Option code -CB).These economical units provide controlled concentration of sample vials through the application of nitrogen gas within a heated water bath. The dual band spring hoist assembly provides a simple and effective means of removing samples from the heated water bath. The N-EVAP’s circular rotating design permits each sample to be accessible from the front of the instrument for easy insertion and retrieval. The chrome plated needle valves are individually milled from solid brass, enabling precise, uniform adjustments for your nitrogen blow down. This promotes efficient and safe sample reduction with minimal nitrogen waste. Time tested technology and proven construction ensure a long lasting, user-friendly experience.<ul><li>Gentle: N-EVAP nitrogen evaporators combine nitrogen blow down with a heated bath to gently concentrate delicate samples</li><li>Flexible: An adjustable sample holder design fits a wide variety of sample tubes and vials at once</li><li>Customizable: A large sample holder option can be added to accommodate vials with a larger outside diameter up to 70 mm</li><li>Individualized Control: Optimize evaporation of diverse samples with individual gas flow control at each vial</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_24_Position_N_EVAP_Nitrogen_Evaporator_2_18a854b63f.jpg" alt="Organomation 24 Position N-EVAP Nitrogen Evaporator ." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_24_Position_N_EVAP_Nitrogen_Evaporator_2_18a854b63f.jpg 156w," sizes="100vw" width="1400" height="1400"><h3>STANDARD FEATURES</h3><ul><li>Nitrogen filter</li><li>Adjustable flow meter, 0-20 LPM</li><li>High pressure phthalate free tubing for safety</li><li>High temperature limit switch for safety</li><li>Dual band spring hoist assembly (except in dry bath model)</li><li>Precision needle valve tube assembly</li><li>Needles, 4 inch x 19 gauge with chrome plated brass hub and stainless steel shaft</li></ul><h3>OPTIONS&nbsp;</h3><ul><li>220v wiring harness (Option Code# -2), Cat# 11250-2</li><li>Z-Purge/positive pressure purge case (Option Code# -Z), Cat# 11250-Z</li><li>Acid resistant coating on instrument and needles (Option Code# -RT), Cat# 11250-RT</li><li>Side control box with built-in digital controller, timer, and pressure regulator (Option Code -CB), Cat# 11250-CB</li></ul><h3>SPECS</h3><h4>24 Position N-EVAP (Water Bath)</h4><ul><li>Bath Type: Water</li><li>Instrumental Catalog Number: 11250</li><li>Number of Sample Positions: 24</li><li>Overall Dimension (w × d × h): 16 × 15 × 33 in / 41 × 38 × 84 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 30–70 mm OD</li><li>Gas Flow Meter: 0–20 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: Dual Band Spring Hoist Assembly</li><li>Rotating, Leak Tight Gas Fitting: Standard</li><li>Standard Gas Input Range: 20–30 psig</li><li>Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating: Optional</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number: 9125</li><li>Heating Medium: Water</li><li>Inside Dimensions (Diameter × Depth): 12.0 × 4.5 in / 30.5 × 11.4 cm</li><li>Outside Dimensions (w × d × h): 16 × 15 × 7 in / 41 × 38 × 18 cm</li><li>Total Wattage: 900 W</li><li>Bath Temperature Range: 30–90 °C</li><li>Temperature Controller Type: Mechanical Thermostat</li><li>Controller Accuracy: ±2 °C</li></ul><h4>24 Position N-EVAP (Dry Bath)</h4><ul><li>Bath Type: Dry</li><li>Instrumental Catalog Number: 11250-DA</li><li>Number of Sample Positions: 24</li><li>Overall Dimension (w × d × h): 16 × 15 × 27.5 in / 41 × 38 × 70 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 30–70 mm OD</li><li>Gas Flow Meter: 0–20 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: None/Fixed</li><li>Rotating, Leak Tight Gas Fitting: N/A</li><li>Standard Gas Input Range: 20–30 psig</li><li>Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating: Optional</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number: 5125</li><li>Heating Medium: Aluminum Beads (Glass Beads in RT Models)</li><li>Inside Dimensions (Diameter × Depth): 12.0 × 4.5 in / 30.5 × 11.4 cm</li><li>Outside Dimensions (w × d × h): 16 × 15 × 7 in / 41 × 38 × 18 cm</li><li>Total Wattage: 540 W</li><li>Bath Temperature Range: 40–130 °C</li><li>Temperature Controller Type: Mechanical Thermostat</li><li>Controller Accuracy: ±2 °C</li></ul><h4>24 Position N-EVAP (No Bath)</h4><ul><li>Bath Type: None</li><li>Instrumental Catalog Number: 11250-O</li><li>Number of Sample Positions: 24</li><li>Overall Dimension (w × d × h): 16 × 15 × 31.75 in / 41 × 38 × 81 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 30–70 mm OD</li><li>Gas Flow Meter: 0–20 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: Dual Band Spring Hoist Assembly</li><li>Rotating, Leak Tight Gas Fitting: Standard</li><li>Standard Gas Input Range: 20–30 psig</li><li>Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating: Optional</li></ul><h3>MODELS</h3><h5>Catalog Number &nbsp;/&nbsp;&nbsp;&nbsp;Bath Type</h5><ul><li>11250: Water Bath</li><li>11250-NT: No Teflon, Water Bath*</li><li>11250-DA: Dry Bath</li><li>11250-O: No Bath**</li></ul>* No Teflon (-NT) units designed for PFAS analysis using EPA methods 533, 537 and 537.1. **All “-O” models come with a base and stand assembly instead of a heated bath. These instruments are designed for evaporation procedures performed at ambient temperature.<h3>ACCESSORIES</h3><ul><li>Large vessel sample holder, 8 positions, for vial outside diameters of 30-70 mm (cat# NA1228)</li><li>Nitrogen generator (cat# NA1955)</li><li>Pasteur pipette adapters (cat# NA0636)</li><li>Pressure reducing regulator 0-160 psi (cat# NA0630)</li><li>High temperature silicone fluid (cat# NA1240)</li><li>Various needle sizes and gauges</li></ul><h3>REPLACEMENT PARTS</h3><ul><li>P0627: Valve Tube Assembly – Post 1997</li><li>P0607: Luer &amp; washer for N-EVAP valve tube</li><li>P0634: Tube Fitting nylon 3 part for N-EVAP valve tube</li></ul>

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