<p><strong>You may have the best HPLC system on the market, but to maximize your investment, you also need the best software to control the system and manage the data. If the software is complex to use, inflexible or lacking in functionality, it can greatly reduce your lab productivity, creating bottlenecks and inefficiencies. Furthermore, this can lead to unreliable results, increased error rates, cost implications and ultimately, a decrease in overall laboratory performance. By selecting the right Chromatography Data System (CDS) designed to meet current laboratory needs, you can eliminate errors and drive productivity with data that is accurate, trustworthy and secure.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Elevate_Your_HPLC_Performance_with_a_Modern_CDS_cc757246f7.jpg" alt="Thermo Fisher Scientific: Elevate Your HPLC Performance with a Modern CDS." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Elevate_Your_HPLC_Performance_with_a_Modern_CDS_cc757246f7.jpg 245w," sizes="100vw" width="1024" height="512"></p><h3><strong>Be flexible and be in control</strong></h3><p>So, what if you have multiple HPLC’s from different vendors? <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Thermo Scientific Chromeleon CDS</strong></a> offers full control over the widest range of HPLC and other chromatography instruments, including those from third-party manufacturers. This ensures you can maintain flexibility, while connecting and controlling your HPLC systems effortlessly. With features, such as auto-generated instrument panels that provide fast access to commands and live analysis plots, you can simplify navigation and enhance the overall user experience, making it easier to manage and monitor instruments.</p><h3><strong>Streamline your method development and validation</strong></h3><p>Support for your method development and validation needs is taken care of with <strong>predefined ICH method validation templates and built-in tools for method conversion, alongside integration with specialized software for automated and intelligent HPLC method development</strong>. This integration facilitates faster and more efficient method optimization and robustness testing, while the secure centralized data storage builds the perfect platform for compliance and future data review, providing a complete solution from method development to validation.</p><h3><strong>Robust compliance and secure data management</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/sp_70761_cds_ensure_compliance_sp70761_en_fd2abc669a.pdf"><strong>Compliance and security</strong></a> can be a crucial aspect of any HPLC operation, and Chromeleon CDS effectively addresses these needs. Your instrument management starts with fast integrated wizard-driven instrument qualification covering IQ, OQ and PQ with predefined templates and reports to optimize the instrument qualification process. The software employs a privilege-based approach to control access to both the instruments and the system, ensuring that only authorized and qualified personnel can interact with them. Dedicated instrument audit trails track all actions and will provide you with a full history that is searchable ensuring traceability, safeguarding the integrity of your data and operations.</p><h3><strong>Keep your instruments up and running</strong></h3><p>Productivity is only maintained if your HPLCs are operational and available for use. Integrated diagnostic tests offer insight into key information such as lamp operating hours or piston seal wear with warning limits for timely replacements. The <strong>active monitoring of service and qualification status</strong> allows for convenient maintenance scheduling and prevents unnecessary instrument downtime. An overview of diagnostic outcomes can also be produced as part of a routine health check ensuring that your HPLC instruments are always in optimal condition.</p><h3><strong>Get more right-first-time results</strong></h3><p>How can you prevent delays, time-consuming investigations, and ensure your analytical sequence runs correctly the first time? Chromeleon CDS offers you solutions to minimize user interaction, such as ready checks that automatically verify instrument configuration, methods, and sequences for issues, and automated system equilibration, which ensures the first injection is always good, eliminating the need for blank injections at the start of a sequence saving time and solvent. Automated shutdown procedures will manage a completed run, ensuring safe shutdown, system flushing, or maintaining a low flow rate to prevent component damage. Built-in system suitability tests with the ability to make in-run decisions, such as pause, stop or continue will maintain the integrity of your data and allow you to perform actions like re-injections and auto-dilutions for when samples are outside acceptable tolerance limits.<strong> Streamlining and automating the entire process of sequence creation is achieved through </strong><a target="_blank" rel="noopener noreferrer" href="https://documents.thermofisher.com/TFS-Assets/CMD/brochures/SP-70758-CDS-Chromeleon-Streamline-Workflow-SP70758-EN.pdf"><strong>eWorkflow procedures</strong></a>. These pre-defined templates contain all associated methods and reports, so your HPLC sequence can be automatically generated with just a few clicks, reducing errors, minimizing training, and producing reliable results faster.</p><h3><strong>A software designed to optimize HPLC lab efficiency</strong></h3><p>Chromeleon CDS is a no-compromise solution for your HPLC systems, designed to provide you with faster and better results through enhanced control, flexibility, diagnostics, right-first-time results, and compliance. Its user-friendly interface, comprehensive method development and validation tools, secure data management, and advanced diagnostics make it an indispensable tool for your HPLC laboratory. Find out more by downloading the case study: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_003880_hplc_vanquish_sanofi_optimize_manufacturing_drugs_cs003880_na_en_cf986bf4cc.pdf"><strong>Leveraging a Vanquish UHPLC system and Chromeleon CDS to optimize the manufacturing process</strong></a> or visiting <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromatography Data System (CDS)</strong></a>.</p><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a><strong>&nbsp;#Chromeleon #ChromatographyDataSystem #HPLC #UHPLC</strong></p><section><blockquote><h5><strong>Peter Zipfell</strong></h5><p>For over 25 years, he has worked extensively with analytical hardware and software transitioning from LC-MS method development through HPLC technical support to chromatography data systems. His focus has always been to support our customers by delivering software solutions across multiple industries to enable them to improve their current workflows and increase productivity.</p></blockquote></section>

Elevate Your HPLC Performance with a Modern CDS

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/"><strong>ISC 2026</strong></a></h3><p>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314"><strong>International Symposium on Chromatography (ISC)</strong></a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.</p><p>The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.</p><p>As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.</p><h3><strong>ISC 2026 SYMPOSIUM KEY DATES</strong></h3><h4><strong>6-10 SEPTEMBER 2026</strong></h4><ul><li><strong>15 January 2026:</strong> Opening of Early-bird Registration &amp; Abstract submission</li><li><strong>11 March 2026: </strong>Deadline for abstract submission (orals)</li><li><strong>21 April 2026: </strong>Sending acceptance letters (orals)</li><li><strong>15 May 2026: </strong>Deadline of early-bird registration and payment &amp; Author registration deadline (orals)</li><li><strong>1 June 2026: </strong>Preliminary detailed program on web</li><li><strong>1 June 2026: </strong>Deadline for abstract submission (posters)</li><li><strong>16 June 2026: </strong>Sending acceptance letters (posters)<ul><li>Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.</li></ul></li><li><strong>30 June 2026:</strong> Author registration deadline (posters)</li><li><strong>30 July 2026:</strong> Deadline for abstract submission (late-breaking posters)<ul><li>without the possibility of competing for the Best Poster Award</li></ul></li><li><strong>11 August 2026: </strong>Sending acceptance letters (late-breaking posters)</li><li><strong>18 August 2026:</strong> Author registration deadline (late-breaking posters)</li><li><strong>25 August 2026: </strong>Deadline for late registration &amp; payment&nbsp;</li><li><strong>6-10 September 2026: </strong>Symposium</li></ul><h3><strong>REGISTRATION</strong></h3><blockquote><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Register HERE for the ISC 2026</strong></a></p></blockquote><h3><strong>ABSTRACT SUBMISSION</strong></h3><blockquote><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Submit your Abstract HERE</strong></a></p></blockquote><h3><strong>SCIENTIFIC PROGRAM</strong></h3><h4><strong>SHORT COURSES</strong></h4><h5><strong>SC 3 Interpretation of Mass Spectra: Basic Introduction for Chromatographers</strong></h5><p><strong>🗓️ SUNDAY, 6 SEPTEMBER 2026</strong></p><p><strong>🕗 8:30 – 11:45</strong></p><p>Mass spectrometry has become an essential tool in modern liquid chromatography, yet many chromatographers receive limited formal training in mass-spectral interpretation. This introductory short course provides a practical guide to understanding and interpreting mass spectra generated by the atmospheric-pressure ionization techniques coupled with LC: electrospray ionization (ESI), atmospheric-pressure chemical ionization (APCI), and atmospheric-pressure photoionization (APPI). The course begins by outlining the information that mass spectrometry adds beyond a chromatogram and clarifying which analytical questions mass spectrometry can – and cannot – answer. Participants receive a concise refresher on mass-spectrometric fundamentals, along with an introduction to key terminology. The principles and practical consequences of ionization methods are then discussed, with emphasis on how ionization physics, LC conditions, and mobile-phase additives shape spectral appearance. Building on this foundation, the course develops practical skills for interpreting LC-ESI spectra: locating the molecular ion, determining charge state, recognizing common adducts, distinguishing in-source artefacts, and using isotope patterns to support elemental-composition hypotheses. Participants then explore how MS/MS fragmentation provides structural clues, with straightforward rules of thumb for neutral losses and class-specific fragmentation behaviors. The course concludes with an integrative exercise that synthesizes chromatographic, full-scan, and MS/MS information to support spectral interpretation. By the end, participants will be equipped with the essential skills needed to interpret LC-MS spectra effectively and to apply mass-spectrometric reasoning in routine chromatographic analysis.&nbsp;</p><h4><strong>Lecturers</strong></h4><h5><strong>Josef Cvačka</strong></h5><ul><li>Josef Cvačka is head of the Mass Spectrometry Group at the Institute of <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/62"><strong>Organic Chemistry and Biochemistry of the Czech Academy of Sciences</strong></a> and an associate professor at the Faculty of Science, Charles University in Prague. His research focuses on the structural analysis of bioactive organic compounds using advanced mass-spectrometric techniques. He develops methods for pinpointing double-bond and methyl-branching positions in lipids and aims to discover new lipid classes in biological samples. His laboratory also designs new ion sources for MS and HPLC/MS. He teaches and supervises students at Charles University and founded the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=Czech+Museum+of+Mass+Spectrometry"><strong>Czech Museum of Mass Spectrometry</strong></a>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Josef_Cvacka_5cc8a0d1d4.jpg" alt="ISC 2026: Josef Cvačka" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Josef_Cvacka_5cc8a0d1d4.jpg 156w," sizes="100vw" width="510" height="510"></p>

ISC 2026 Short Course 3 - Interpretation of Mass Spectra: Basic Introduction for Chromatographers

<p><strong>Eurachem and CITAC welcome analysts interested in the evaluation of chemical analysis uncertainty and in how to use this information in results interpretation. The Eurachem Week 2026 will begin with a training course on “Evaluation of the measurement uncertainty from in-house precision and recovery data” scheduled for Sunday, 10 May 2026. A two-days workshop on “Quality in Analytical Measurements: Uncertainty Evaluation and Results Interpretation” open to all interested participants will take place from 11 to 12 May 2026. On 13 May 2026, the Eurachem Working Groups will convene, followed by the Eurachem General Assembly, which will bring together the Executive and national delegates on 14 and 15 May. Both Working Group Meetings and the General Assembly are restricted to their members.</strong></p><p>The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation.</p><p>For many analytical applications, simplified uncertainty evaluations can determine uncertainty values that meet the defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation and quality control. There will be a discussion of how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.</p><blockquote><h5><strong>New Eurachem guidance on using in-house precision and recovery data will be discussed at the workshop.</strong></h5></blockquote><p>Topics will also include the validation and uncertainty evaluation for qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling. Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.</p><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://conferences.chemistry.pt/register/eurachem2026"><strong>Register here for the workshop</strong></a></p></blockquote><h4><strong>Registration Fees</strong></h4><h5><strong>Early bird (EUR) - Until April 15th</strong></h5><ul><li><strong>Workshop: Regular participant (11 &amp; 12 May 2026): </strong>400 EUR</li><li><strong>Workshop: Student (11 &amp; 12 May 2026): </strong>250 EUR</li><li><strong>Eurachem Working Group<sup>1</sup> (13 May 2026):</strong> 75</li><li><strong>General Assembly<sup>2</sup> (14 &amp; 15 May 2026): </strong>250</li><li><strong>Training On Uncertainty Evaluation<sup>3</sup> (10 May 2026):</strong> 150</li></ul><h5><strong>After April 15th</strong></h5><ul><li><strong>Workshop: Regular participant (11 &amp; 12 May 2026): </strong>450 EUR</li><li><strong>Workshop: Student (11 &amp; 12 May 2026):</strong> 300 EUR</li><li><strong>Eurachem Working Group<sup>1</sup> (13 May 2026): </strong>100</li><li><strong>General Assembly<sup>2</sup> (14 &amp; 15 May 2026):</strong> 300</li><li><strong>Training On Uncertainty Evaluation<sup>3</sup> (10 May 2026): </strong>200</li></ul><blockquote><p>§ - <strong>50 EUR reduction for members of Eurachem</strong>, CITAC, SPQ, RELACRE, ForMEQ and SPMet at the workshop.</p><p>10% reduction for organisations that registered more than one participant.</p><p><sup>1 </sup>- Working group members</p><p><sup>2</sup> - Eurachem members</p><p><sup>3</sup> - 50% reduction for workshop participants</p></blockquote><h3><strong>Workshop</strong></h3><h4><strong>Eurachem/CITAC Workshop on Quality in Analytical Measurements:</strong></h4><h5><strong>Uncertainty Evaluation and Results Interpretation</strong></h5><p>The results of qualitative and quantitative chemical analyses should have an acceptable uncertainty, which should ideally be reported and considered in results interpretation. For many analytical applications, simplified uncertainty evaluations can determine uncertainty values meeting defined requirements for this parameter. The workshop will focus on the key technical challenges involved in practical evaluations of measurement uncertainty based on precision and recovery data gathered during in-house method validation. It will be discussed how to model the variation of the measurement uncertainty within the analytical range and how to handle divergent recovery values from the analysis of various reference materials. A session on the use of measurement uncertainty in conformity assessment will explore how the risk of false conformity decisions can be managed.</p><p>Topics will also include the validation and uncertainty evaluation of qualitative analyses with particular attention to current accreditation requirements for these types of analysis. The last session of the workshop will be dedicated to the evaluation of measurement uncertainty arising from sampling and using it to judge the fitness for purpose, and hence validation, of measurement procedures that include sampling.</p><p>Four sessions of the workshop will include engaging breakout sessions where participants will have the chance to share their views about challenging aspects of the analytical work. Participants are invited to propose posters and oral communications on session topics or any other relevant topic for analytical chemists or stakeholders of the analytical work.</p><h3><strong>Training Course</strong></h3><h4><strong>Evaluation of the measurement uncertainty from in-house precision and recovery data</strong></h4><ul><li>10 May 2026</li></ul><p>A course on the fundamentals of the evaluation of the measurement uncertainty from in-house precision and recovery data will be held on Sunday, 10 May 2026. This training is targeted for analysts with a basic understanding of the measurement uncertainty concept, how uncertainty components propagate, and how the combined uncertainty is expanded. Following the morning presentation of the theory of uncertainty evaluation, the afternoon will be dedicated to applying the theory to real-world cases. Trainees should have basic skills in using Microsoft Excel spreadsheets and bring a laptop with Microsoft Excel to complete the exercises. The interaction between trainers and trainees will be promoted to guarantee learning efficiency.</p><h5><strong>Trainers:</strong></h5><ul><li>Ricardo Bettencourt da Silva, Faculdade de Ciências da Universidade de Lisboa, Portugal (rjsilva@ciencias.ulisboa.pt)</li><li>Stephen L. R. Ellison - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li><li>Vicki Barwick - UK National Measurement Laboratory (NML) hosted at LGC, United Kingdom</li></ul><h4><strong>Agenda</strong></h4><h5><strong>8:00 Registration</strong></h5><h5><strong>9:00 Opening</strong></h5><h5><strong>9:05 Identifying, combining, and expanding uncertainty components: Theory and examples</strong></h5><h5><strong>9:45 Precision uncertainty: Theory and examples</strong></h5><h5><strong>10:30 </strong>Coffee break</h5><h5><strong>10:50 Trueness-related uncertainty: Theory and examples</strong></h5><h5><strong>12:00 Additional questions and discussion</strong></h5><h5><strong>12:30 </strong>Lunch</h5><h5><strong>13:30 Application example 1</strong></h5><h5><strong>15:30 </strong>Coffee break</h5><h5><strong>15:50 Application example 2</strong></h5><h5><strong>17:00 Additional questions and discussion</strong></h5><h5><strong>17:30 Closing</strong></h5><h3><strong>Venue</strong></h3><p>The series of Eurachem events will be held in:</p><ul><li>Meliã Lisboa Aeroporto ****</li><li>Rua C,2 1749-125 Lisboa, Portugal&nbsp;</li></ul>

Eurachem/CITAC Workshop on Quality in Analytical Measurements 2026

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Thermo Fisher Scientific

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Waters ACQUITY PREMIER UPLC System

Get the highest limits of detection, more consistent results, and better recovery, so you can see what you couldn’t before.

<p class="cke-user_style-important"><strong>Redefining separation science. Again.</strong></p><p data-pm-slice="1 3 []"><strong>The most significant innovation in separation science since we introduced UPLC™ in 2004, the ACQUITY™ Premier Solution reduces variability associated with metal-sensitive analytes - without time-consuming tasks like system and column passivation. 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The result is more gaussian peaks, reduced chromatographic coelution, and superior spectral quality.</span></p><figure class="image"><img style="aspect-ratio:1291/1172;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_PREMIER_Solution_4_def1e84e9a.jpg" alt="Waters ACQUITY PREMIER Solution: Improve spectral quality and analyte identification." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_PREMIER_Solution_4_def1e84e9a.jpg 171w," sizes="100vw" width="1291" height="1172"></figure><h3><span><strong>Global Services: Committed to your success</strong></span></h3><p data-pm-slice="1 1 []"><span>As part of the ACQUITY Premier experience, one of our applications specialists will work with you to ensure you are getting everything you need from your system. 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Waters ACQUITY UPLC H-Class PLUS System

Simplify and streamline your method development workflow. The ACQUITY H-Class PLUS Quaternary System automatically screens multiple column and eluent combinations to identify the separation conditions that provided the best chromatographic resolution.

<div><div><h4><strong>Performance that advances your lab</strong></h4></div></div><div><div><p><strong>Whether your goal is to rapidly develop new methods or to routinely analyze large numbers of incoming samples, the ACQUITY UPLC H-Class PLUS System can help you decrease the time to result, while increasing the depth and quality of information received from your sample analysis.</strong></p><p>With the ACQUITY UPLC H-Class PLUS System, you can improve laboratory productivity by transitioning methods to UPLC/UHPLC technology, improve the characterization of your most complex samples through enhanced resolution and leverage advanced tools to simplify and streamline your method development workflow.</p><div><div><div><div><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_H_Class_PLUS_System_5_55c4c9e990.jpg" alt="Waters ACQUITY UPLC H-Class PLUS System: Simplify and streamline your method development workflow. The ACQUITY H-Class PLUS Quaternary System automatically screens multiple column and eluent combinations to identify the separation conditions that provided the best chromatographic resolution. The system provides on-demand solvent blending and support for any analytical LC column, making it an ideal choice for modernizing existing or developing new methods." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_H_Class_PLUS_System_5_55c4c9e990.jpg 234w," sizes="100vw" width="1024" height="682"></p><div><div><ul><li><strong>Get the flexibility of multi-solvent blending</strong> - Blend up to nine solvents with integrated solvent-select valve with the Quaternary Solvent Manager&nbsp;</li><li><strong>Deliver precise and accurate binary solvent blending</strong> - Blend up to four solvents with integrated solvent-select valve with the Binary Solvent Manager</li><li><strong>Get high-precision injections with direct inject sampling&nbsp;</strong>- The needle-in-flow path design ensures an accurate needle seal at high pressure</li><li><strong>Get accurate temperature control across the entire column</strong> - Configurable for 1 to 6 columns with active preheating</li><li><strong>Automate the formulation of mobile phases</strong> - Significantly reduce the time you spend in the prep lab with&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/waters/global/Auto%E2%80%A2Blend-Plus/nav.htm?cid=134623262"> Auto•Blend Plus </a>Technology</li><li><strong>Transfer methods more easily</strong> - Easily adjust for system volume differences when transferring methods from an alternative LC system without alteration to the method table using Gradient SmartStart </li><li><strong>Wide software support</strong> – ACQUITY UPLC H-Class PLUS System is supported by  <strong>Empower, MassLynx, UNIFI</strong>, and several 3rd party software packages</li></ul></div></div><div><div><h5><strong>Recommended Use</strong></h5><p>Improving laboratory productivity by transitioning methods to UPLC technology.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_H_Class_PLUS_System_6_2e9f1740ab.jpg" alt="Waters ACQUITY UPLC H-Class PLUS System: A highly reliable and robust LC-MS system without any compromise in speed, resolution, or sensitivity, especially in everyday settings. The ACQUITY H-Class PLUS Binary System combines an optimized flow path resistant to clogging, stable high-pressure gradient formation, and support for sub-2-µm to 5-µm particle columns to deliver the ideal choice for reproducible everyday LC-MS analyses with any tandem quad or Q-ToF." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_H_Class_PLUS_System_6_2e9f1740ab.jpg 234w," sizes="100vw" width="1024" height="682"></p></div></div><div><div><h3><strong>Discover the UPLC difference</strong></h3><p>The <strong>ACQUITY UPLC H-Class PLUS System</strong> is the next evolution of ultra-performance instrumentation, providing the <strong>high resolution</strong> of a <strong>quaternary or binary liquid chromatography (LC) system</strong>.</p><p>Achieving <strong>true UPLC performance</strong> requires that system dispersion (or extra-column band spread) be matched to the peak widths associated with narrow bore columns packed with <strong>sub-2-μm particles</strong>. While other systems might be designed for high pressure, it doesn’t mean they're designed to deliver the <strong>sharp peaks of UPLC performance</strong> and the <strong>ACQUITY UPLC H-Class PLUS System</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_H_Class_PLUS_System_cd9c6e5cda.jpg" alt="Waters ACQUITY UPLC H-Class PLUS System: Comparison of the same method with the same column on a low-dispersion ACQUITY UPLC H-Class PLUS System versus a higher-dispersion UHPLC system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_H_Class_PLUS_System_cd9c6e5cda.jpg 245w," sizes="100vw" width="1024" height="555"></p></div></div><div><div><h3><strong>Take your methods to the next level</strong></h3><p>Leverage the benefits of <strong>UPLC technology</strong> to improve your existing <strong>HPLC methods</strong>. By scaling your methods to UPLC, your laboratory will benefit from the combination of <strong>increased resolution, sensitivity, and speed</strong> that comes with modern small particle chemistries.</p><p>Designed to accommodate all of your LC method needs, the <strong>ACQUITY UPLC H-Class PLUS System</strong> is ideally suited to <strong>future-proof your laboratory</strong>, enabling the support of existing HPLC methods now, and provide <strong>significant productivity and cost benefit</strong> when utilized for UPLC methods.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_H_Class_PLUS_System_2_97e7735374.jpg" alt="Waters ACQUITY UPLC H-Class PLUS System: The USP analysis of diclazuril and organic impurities was scaled from HPLC to UHPLC to UPLC. The UPLC method resulted in a 4x reduction in run time and a 10x reduction in solvent consumption resulting in improved sample throughput and reduced cost per analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_H_Class_PLUS_System_2_97e7735374.jpg 245w," sizes="100vw" width="1024" height="613"></p></div></div><div><div><h3><strong>Discover the best method for the best results</strong></h3><p>Get the <strong>versatility</strong> to discover the best set of chromatographic conditions for your sample, providing a <strong>more robust method</strong>. The flexibility of the <strong>ACQUITY UPLC H-Class PLUS Quaternary System</strong> allows you to <strong>automatically screen important method parameters</strong>, including:</p><ul><li>Up to <strong>six columns</strong> in independently temperature-controlled compartments</li><li>pH and ionic strength with <a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/waters/Auto%E2%80%A2Blend-Plus/nav.htm?cid=134623262"><strong>Auto•Blend Plus</strong></a><strong> Technology</strong></li><li><strong>Optional and integrated solvent selection valve</strong> expands access to six additional mobile phase lines&nbsp;</li><li><strong>11 unique gradient profiles</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_H_Class_PLUS_System_3_fc2b3f925b.jpg" alt="Waters ACQUITY UPLC H-Class PLUS System: (A) Auto·Blend Plus method gradient table for trastuzumab pH optimization. (B) pH optimization on trastuzumab charge variants separation. Gradient: 20 mM MES buffer, 50–155 mM NaCl in 15 min." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_H_Class_PLUS_System_3_fc2b3f925b.jpg 245w," sizes="100vw" width="1024" height="622"></p></div></div><div><div><h3><strong>Deliver greater speed and precision for routine analyses</strong></h3><p>The <strong>ACQUITY UPLC H-Class PLUS Binary System</strong> combines the <strong>proven reliability and performance</strong> of the H-Class PLUS System with the <strong>precision and lowest system volume</strong> offered by our <strong>high-pressure mixing binary solvent manager</strong>, allowing you to:</p><ul><li>Accommodate the <strong>most challenging sample matrices</strong></li><li>Tackle applications with <strong>long shallow gradients</strong></li><li><strong>Improve the throughput</strong> of your methods</li></ul><p><strong>Combine </strong>the capabilities of the <strong>ACQUITY UPLC H-Class PLUS Binary System</strong> with <strong>Waters </strong><a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/waters/global/Tandem-Quadrupole-%28-Triple-Quadrupole-%29-Mass-Spectrometry/nav.htm?cid=134656172"><strong>Tandem quadruple technology</strong></a><strong> </strong>for routine quantitative UPLC-MS/MS applications, so you can confidently quantify and trace components in the most complex of samples.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_H_Class_PLUS_System_4_618bbb6347.jpg" alt="Waters ACQUITY UPLC H-Class PLUS System: Direct transfer without a gradient delay offers the opportunity for method improvement with the analysis time going from 5 minutes to 3 minutes representing a 40% reduction in runtime." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_H_Class_PLUS_System_4_618bbb6347.jpg 245w," sizes="100vw" width="1024" height="600"></p><h3><strong>Specifications</strong></h3><ul><li><strong>Maximum operating pressure</strong>: 15,000 psi</li><li><strong>pH range</strong>: 1–12.5 (<i><span>For specific test conditions, contact your Waters sales representative)</span></i></li><li><strong>Operating flow rate range</strong>: Up to 2.2 mL/min</li><li><strong>Sample flow path</strong>: Stainless-steel</li><li><strong>Sample carryover</strong>: ≤0.002% (Caffeine) under UV conditions</li><li><strong>Sample compartment</strong>: 4–40 °C</li><li><strong>Pump options</strong>: Binary, Quaternary</li><li><strong>Solvent conditioning</strong>: Active Pre-heating</li><li><strong>Column tracking</strong>: eCord Technology tracks column information and archives column usage</li><li><strong>Column capacity</strong>: Up to 6 columns of 150 mm length and up to 4.6 mm I.D.</li><li><strong>Maximum sample capacity</strong>: Up to 20 plates (with Sample Organizer)</li><li><strong>Detector options</strong>:&nbsp;<ul><li>PDA Detector</li><li>TUV Detector</li><li>FLR Detector</li><li>RI Detector</li><li>ELS Detector</li><li>Mass Spectrometers</li></ul></li><li><strong>External control</strong>:&nbsp;<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/627">Empower Software</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/635">MassLynx Software</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1544">waters_connect</a></li><li>UNIFI Scientific Information System</li></ul></li><li><strong>Physical specifications</strong> <strong>(QSM or BSM, SM-FTN, CHA):</strong><ul><li>Width: 34.3 cm (13.5 in.)</li><li>Height: 71.1 cm (28.0 in.)</li><li>Depth: 71.2 cm (28.0 in.)</li></ul></li></ul></div></div></div></div></div></div></div></div>

Waters ACQUITY UPLC I-Class PLUS System

With the ACQUITY UPLC I-Class PLUS System, your lab can achieve highly efficient, rapid separations from ultra-low dispersion and delay volume.

<div><div><h4><strong>Complex chromatography challenges, solved</strong></h4></div></div><div><div><p><strong>Looking for answers to the most complex scientific challenges is what you do, and the scientific tools you deploy and the information they provide can make all the difference. With industry-leading separations performance, the ACQUITY UPLC I-Class PLUS System provides new possibilities for maximizing the resolution and sensitivity of your methods, enhancing the characterization of your samples, and improving productivity to advance the science of your laboratory.</strong></p><div><div><div><div><p>With the <strong>ACQUITY UPLC I-Class PLUS System</strong>, your lab can achieve <strong>highly efficient, rapid separations</strong> from <strong>ultra-low dispersion and delay volume</strong>. The system enables your lab to get <strong>narrow, ultra-efficient peaks</strong>, enhancing the <strong>sensitivity of any mass spectrometer</strong> and simplifying the characterization of the most complex sample.</p><ul><li><strong>Achieve precise and accurate binary solvent blending</strong> with the Binary Solvent Manager, ideal for up to four solvents with integrated solvent-select valve</li><li><strong>Get sample injection versatility</strong>, depending upon your application with the flow-through needle and fixed loop injector options</li><li><strong>Manage ultra-low carryover</strong> through programmable method settings to ensure compatibility even with the most sensitive mass spectrometers</li><li><strong>Get accurate temperature control</strong> across the entire column, configurable for 1 to 2 columns with active preheating</li><li><strong>Improve the performance of any mass spectrometer</strong> with the highest chromatographic resolution which minimizes interference from co-elutions</li><li><strong>Minimize the time and cost</strong> associated with annual qualification with the Waters Empower-based automated system qualification tool (SQT)</li><li><strong>Supported by Empower, Masslynx, UNIFI</strong>, and several third-party software packages</li></ul></div></div><div><div><h5><strong>Recommended Use</strong></h5><p><strong>Enhance the characterization of your samples</strong>, while <strong>improving productivity</strong> to advance the science of your laboratory.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_I_Class_PLUS_System_9b05f209f6.jpg" alt="Waters ACQUITY UPLC I-Class PLUS System: ACQUITY UPLC I-Class PLUS System FTN-H PDA angled." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_I_Class_PLUS_System_9b05f209f6.jpg 245w," sizes="100vw" width="1024" height="637"></p><div><div><div><div><h3><strong>Get a clearer picture of your sample</strong></h3><p>Get improved resolution through <strong>reduced system dispersion</strong> with the <strong>ACQUITY UPLC I-Class PLUS System</strong>, providing separations that can amplify your research.</p><p><strong>Shorten analysis times</strong>, <strong>reduce solvent usage</strong>, and <strong>speed access to the data</strong> you need for critical decisions. Designed to fit into your existing LC workflow, the ACQUITY UPLC I-Class PLUS System provides a <strong>clear view into what lies within the sample</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_I_Class_PLUS_System_2_c2d3e9e7d9.jpg" alt="Waters ACQUITY UPLC I-Class PLUS System: In this example, the impurity analysis of tetracaine was run under the same conditions on the ACQUITY UPLC I-Class PLUS System (system band spread of 4 µL) and a UHPLC system (system band spread of 20 µL). Significantly better resolution was achieved on the ACQUITY UPLC I-Class PLUS System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_I_Class_PLUS_System_2_c2d3e9e7d9.jpg 245w," sizes="100vw" width="1024" height="595"></p></div></div></div></div></div></div></div></div><div><div><h3><strong>An inlet that improves the performance of any MS</strong></h3><p>The ACQUITY UPLC I-Class PLUS System is designed specifically for the <strong>rapid pace of laboratories</strong> on the <strong>cutting edge of research</strong> where <strong>LC-MS plays a critical role</strong>.</p><p><strong>With the ACQUITY UPLC I-Class PLUS System, your lab will:</strong></p><ul><li><strong>Improve resolution and ionization efficiency</strong> with narrow peak widths, enhancing <strong>mass spectrometry sensitivity</strong></li><li><strong>Enhance sensitivity</strong> through <strong>industry-leading carryover performance</strong></li><li><strong>Improve sample characterization</strong> through <strong>selective isolation</strong> with multidimensional UPLC configurations</li><li><strong>Achieve exceptionally fast analysis times</strong> with <strong>ultra-low delay volume</strong></li><li><strong>Achieve ultimate peak capacity</strong> with <strong>CORTECS Columns</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_I_Class_PLUS_System_3_d8d5bb46be.jpg" alt="Waters ACQUITY UPLC I-Class PLUS System: A high sensitivity UPLC-MS/MS bioanalytical methodology for the quantification of midazolam and imipramine in rat plasma using the Xevo TQ Absolute Tandem Quadrupole Mass Spectrometer in combination with an ACQUITY UPLC I-Class PLUS System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_I_Class_PLUS_System_3_d8d5bb46be.jpg 182w," sizes="100vw" width="1024" height="878"></p></div></div><div><div><h3><strong>Achieve ultimate peak capacity with CORTECS Columns</strong></h3><p>When paired with <a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/nextgen/global/products/columns/cortecs-columns.html"><strong>CORTECS 1.6 µm solid-core columns</strong></a>, the ACQUITY UPLC I-Class PLUS System enables scientists to achieve new levels of resolution, sensitivity, and chromatographic performance. With <strong>CORTECS Columns</strong> and the ACQUITY UPLC I-Class PLUS System, you can increase resolution for even your toughest samples and get the flexibility and power you need to rapidly separate a wide array of compounds.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_I_Class_PLUS_System_4_2dfd32bd0d.jpg" alt="Waters ACQUITY UPLC I-Class PLUS System: By pairing the ultra-low dispersion ACQUITY UPLC I-Class PLUS System with high-efficiency CORTECS Columns, you’ll achieve new levels of UPLC performance. These 1.6 µm columns deliver exceptional levels of efficiency, performance, and throughput, resulting in narrower peaks and higher peak capacity." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_I_Class_PLUS_System_4_2dfd32bd0d.jpg 210w," sizes="100vw" width="1024" height="761"></p><h3><strong>Specifications</strong></h3><ul><li><strong>Maximum operating pressure</strong>: 18,000 psi</li><li><strong>pH Range</strong>*: 1–12.5</li><li><strong>Operating flow rate range</strong>: Up to 2.0 mL/min</li><li><strong>Sample flow path</strong>: Stainless-steel</li><li><strong>Sample carryover</strong>: &lt;0.001% (Caffeine) under UV conditions</li><li><strong>Sample compartment</strong>: 4–40 °C</li><li><strong>Pump options</strong>: Binary</li><li><strong>Solvent conditioning</strong>: Active Pre-heating</li><li><strong>Column tracking</strong>: eCord Technology tracks column information and archives column usage</li><li><strong>Column capacity</strong>: Up to 2 columns of 150 mm length and up to 4.6 mm I.D.</li><li><strong>Maximum sample capacity</strong>: Up to 20 plates (with Sample Organizer)</li><li><strong>Detector options</strong>:&nbsp;<ul><li>PDA Detector</li><li>TUV Detector</li><li>FLR Detector</li><li>RI Detector</li><li>ELS Detector</li><li>Mass Spectrometers</li></ul></li><li><strong>External control</strong>:&nbsp;<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/627">Empower Software</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/635">MassLynx Software</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1544">waters_connect</a></li><li>UNIFI Scientific Information System</li></ul></li><li><strong>Physical specifications (QSM or BSM, SM-FTN, CHA):</strong><ul><li>Width: 34.3 cm (13.5 in.)</li><li>Height: 71.1 cm (28.0 in.)</li><li>Depth: 71.2 cm (28.0 in.)</li></ul></li></ul></div></div></div></div>

Waters ACQUITY Arc LC System

The ACQUITY™ Arc™ System is an all-in-one platform for HPLC and UHPLC, designed for robust method development and seamless transfer between modern LC systems, addressing a wide range of analytical challenges.

<p class="cke-user_style-important"><strong>Built upon a foundation of reliability</strong></p><p data-pm-slice="1 1 []"><strong>The method development process is changing. New regulations, software and analytical technologies are rapidly changing how methods are designed, transferred, and monitored over their lifecycle. An all-in-one platform for HPLC and UHPLC separations, the ACQUITY™ Arc™ System is designed to meet the spectrum of challenges you face from robust method development to seamless transfer between any modern LC systems.</strong></p><p data-pm-slice="1 1 []">With the <strong>ACQUITY Arc System</strong>, you can experience true plug-and-play method compatibility for HPLC and UHPLC separations. Significant productivity gains can be realized by deploying a single LC platform that allows for the efficient transfer, adjustment, and improvement of methods from any LC platform without compromise in method integrity.</p><figure class="image"><img style="aspect-ratio:768/886;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Arc_System_63246061ea.jpg" alt="Waters ACQUITY Arc System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Arc_System_63246061ea.jpg 136w," sizes="100vw" width="768" height="886"></figure><p data-pm-slice="1 1 []">Laboratory-driven organizations have relied on Waters for over 60 years to deliver reliable, robust, and reproducible solutions to ensure confidence in their analytical results. With over 100,000 LC systems installed, we understand the significant impact the right technology has on your business, and the implications it has on characterizing the quality and safety of your products.</p><p data-pm-slice="1 1 []">Methods with greater agility, robustness, and capacity for change can help you reduce regulatory burden, risk of failure and costs. Visit <a disabled="true">www.methods.waters.com</a> to learn more about how method life cycle management (MLCM) connects your method today to your method tomorrow.</p><h3><strong>Designed for discovery to routine QC applications</strong></h3><p>The <strong>ACQUITY Arc System</strong> is the only available LC system with regulatory compliant-ready hardware and software for both HPLC and UHPLC separations in one instrument. With unrivaled column capacity and Arc Multi-flow path™ technology, the<strong> ACQUITY Arc System</strong> allows you to generate new methods and modernize legacy HPLC methods faster than ever before.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Arc_System_2_c06ba42baa.jpg" alt="Waters ACQUITY Arc System: The ACQUITY Arc System can replicate your established HPLC methods by compensating for these differences with unique features such as the Arc Multi-Flow Path technology and Gradient SmartStart. These innovative attributes enable seamless replication of your existing chromatographic results to meet your acceptance criteria without changes to validated gradient tables." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Arc_System_2_c06ba42baa.jpg 234w," sizes="100vw" width="1024" height="682"></p><h4><strong>Comprehensive detector portfolio</strong></h4><p>High-performance analytical detectors designed to maximize HPLC and UHPLC performance, delivering exceptional sensitivity and linearity for your assays.</p><p>Photodiode array, UV/Vis, fluorescence, refractive index, evaporative light scattering, and mass detection, including the ACQUITY QDa™ Detector.</p><h4><strong>Gradient SmartStart</strong></h4><p>Automatically manage gradient start time and pre-injection steps to maximize sample throughput. Automatically counteract differences in system dwell volume without the need to alter gradient table inputs.</p><h4><strong>Quaternary solvent management</strong></h4><p>Precise and accurate blending of up to four solvents with automated solvent compressibility compensation. Increase solvent flexibility with an optional, integrated solvent select valve, providing access to six additional solvents.</p><h4><strong>Negligible carryover</strong></h4><p>Advanced flow-through needle design minimizes carryover by continuously cleansing the needle during run. User-configurable wash settings provide flexibility to address even the most complex sample matrices.</p><h4><strong>Thermal management options</strong></h4><p>Column manager options available for up to 15 columns ranging in length from 50 mm to 300 mm, with a temperature range of 4 °C to 90 °C. Integrated column selection valve options provide unattended, fast column changeover.</p><h4><strong>Auto•Blend™ Plus Technology</strong></h4><p>Program gradients directly in terms of pH and ionic strength to minimize manual mobile phase preparation, reduce potential for human error, and accelerate method robustness testing for chromatographic methods.</p><h4><strong>Arc Multi-flow path technology</strong></h4><p>Delivers plug-and-play method compatibility with HPLC or UHPLC methods with the flip of a switch.</p><p>Easily replicate or improve established methods by simply selecting between Path 1 (HPLC) or Path 2 (UHPLC) without any manual user intervention.</p><h4><strong>Column Technology</strong></h4><p>Industry-leading selectivity choices to meet the needs of virtually every LC application.</p><h4><strong>Laboratory Informatics</strong></h4><p>Software control within your existing Empower™ or MassLynx™ infrastructure.</p><h3><strong>Replicate your established methods</strong></h3><p data-pm-slice="1 1 []">The <strong>ACQUITY Arc System</strong>, enabled by unique Arc Multi-flow path technology, easily accepts and replicates methods from any HPLC platform, without compromise.&nbsp;</p><p data-pm-slice="1 1 []">Whether you are trying to replicate an out-of-date HPLC method, transfer methods across the organization, or to contract partners, the <strong>ACQUITY Arc System</strong> gives you ultimate flexibility to reproduce, modernize, and transfer existing methods with ease and greater cost efficiency, while preserving the integrity of your methods.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Arc_System_3_c8c7901de3.jpg" alt="Waters ACQUITY Arc System: Analysis run on a Vendor X LC system and replicated on the ACQUITY Arc System. Conditions: 15 to 35% B in 3 min, 35 to 95% B in 2 min; Mobile phase A: 0.1% HCOOH in H 2 O, mobile phase B: 0.1% HCOOH in ACN; Flow rate = 2.0 mL/min; Column: XSelect™ CSH C 18 , 4.6 x 150 mm, 5 μm; Temp. = 30 °C; UV@ 260 nm; 10.0 μL injection volume." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Arc_System_3_c8c7901de3.jpg 245w," sizes="100vw" width="1099" height="596"></p><p>Upgrade your laboratory with a versatile, modern LC system that delivers HPLC and UHPLC method compatibility at the flip of a switch.</p><h3><strong>Modernize your methods</strong></h3><p>The United States Pharmacopeia (USP) is championing pharmacopeial harmonization and modernization efforts, and international organizations are following suit. As a result, the USP is encouraging the modernization of older compendial methods to ensure they are fit for purpose.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Arc_System_4_a1aaab8d02.jpg" alt="Waters ACQUITY Arc System: Quetiapine fumarate system suitability solution analyzed on the ACQUITY Arc System using HPLC, UHPLC, and UPLC™ column/method conditions for the quetiapine impurity method. Peak identification: (1) quetiapine related compound G, (2) quetiapine related compound B, (3) quetiapine desethoxy, and (4) quetiapine." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Arc_System_4_a1aaab8d02.jpg 245w," sizes="100vw" width="1092" height="678"></p><p>Revisions to these guidelines give you more flexibility to modify your existing pharmacopeial methods with modern techniques and technologies, and in some cases avoid revalidation. The <strong>ACQUITY Arc System</strong>, featuring the Waters Columns Calculator, allows you to confidently scale your gradient methods from a 3.5 μm to a 2.5 μm particle, decreasing run times, lowering solvent consumption, and increasing sample throughput.</p><h3><span><strong>Save time. Reduce cost.</strong></span></h3><p data-pm-slice="1 1 []">With the right column, the <strong>ACQUITY Arc System</strong> is the ideal solution to accommodate methods from any LC platform.&nbsp;</p><p data-pm-slice="1 1 []">From concept to production, the transition your product takes through the product development cycle often requires rigorous LC assays to properly characterize and assess its readiness to advance to the next stage. These LC assays are often adapted to accommodate the technology available from one stage to the next, in some cases requiring an adjustment from a smaller particle size (sub-2-μm) to a larger particle size (2.5 μm–5 μm).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Arc_System_5_d9dd95135c.jpg" alt="Waters ACQUITY Arc System: The ACQUITY Arc System enables the support of HPLC and UHPLC methods on a single platform." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Arc_System_5_d9dd95135c.jpg 173w," sizes="100vw" width="959" height="860"></p><p>The <strong>ACQUITY Arc System</strong> provides the flexibility to maximize productivity through efficient and rapid 2.5 μm–2.7 μm UHPLC separations, or to accommodate larger 3.0 μm–5 μm HPLC particles.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Arc_System_6_1ebc2c67e7.jpg" alt="Waters ACQUITY Arc System: Save time. Reduce cost." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Arc_System_6_1ebc2c67e7.jpg 245w," sizes="100vw" width="1683" height="469"></p><h3><span><strong>Mitigate your risk</strong></span></h3><p data-pm-slice="1 1 []">With an expanded range of column manager options enabling up to 15-column switching from 4 °C to 90 °C, the <strong>ACQUITY Arc System</strong> will help you significantly reduce the time spent generating robust methods. Equipped with the plug-and-play ACQUITY QDa Mass Detector, the <strong>ACQUITY Arc System</strong> tracks peaks in your method and reveals hidden coelutions of similar analytes, ensuring you have complete confidence in the reliability and reproducibility of your method now and far into the future.</p><h4><strong>Thermal management options</strong></h4><p data-pm-slice="1 1 []">Active and passive pre-heating options available, with up to 15-column switching from 4 °C to 90 °C. Automated monitoring and tracking of column usage with eCord™ technology available with active pre-heating options.</p><h4><strong>Quaternary solvent management</strong></h4><p data-pm-slice="1 1 []">Accelerate your method development with precise and accurate blending of up to four solvents. Increase solvent flexibility with an optional solvent select valve, providing access to six additional solvents.</p><h4><strong>Auto•Blend Plus Technology</strong></h4><p data-pm-slice="1 1 []">Reduce human error and accelerate method robustness testing for chromatographic methods by programming gradients to control mobile phase pH and ionic strength.</p><h4><strong>Comprehensive detector portfolio</strong></h4><p>Diverse portfolio of detectors for method development, method transfer, and routine use.</p><h4><strong>ACQUITY QDa Detector</strong></h4><p>Mass detection built around the needs of analytical scientists for chromatographic analysis. Robust, reliable and requiring no adjustments, it easily integrates with your<strong> ACQUITY Arc System.</strong></p><h5><strong>Support</strong></h5><p data-start="0" data-end="175">Empower eLearning modules to help train your lab on Empower 3 and Method Validation. Applications support that’s customized based on your method development needs.</p><h5><strong>Consumables</strong></h5><p data-start="177" data-end="410" data-is-last-node="">Industry-leading selectivity choices to meet the needs of virtually every LC application. Quality Control (QC) Reference Material benchmarks your <strong>ACQUITY Arc System </strong>and enables perfect resolution. Certified clean vials.</p><h5><strong>Laboratory Informatics</strong></h5><p>Software control within your existing Empower or MassLynx infrastructure. Empower 3 Method Validation Manager allows you to perform chromatographic method validation in one application. Optional S-Matrix Fusion Software automates your method development according to AQbD guidelines.</p><h3><span><strong>Develop methods that stand the test of time</strong></span></h3><p>Need an orthogonal detection approach to UV in your method development? Streamline your method development with an LC-MS solution that’s as easy to use as photodiode array detection.</p><p>The <strong>ACQUITY Arc System</strong> is fully compatible with the ACQUITY Arc, supporting efficient and robust method development by expanding the information you can get from your system using the same Empower Software. The system automatically pairs qualitative mass spectral data to the peaks in your chromatogram, leaving nothing to chance.</p><ul><li>Confirm the identity of peaks in a separation without injecting standards.</li><li>Identify new peaks in a separation with molecular weight information.&nbsp;</li><li>Detect unresolved peaks and determine if a peak is homogeneously pure.</li><li>Easily track peaks as method conditions are changed.</li></ul><p data-start="272" data-end="600">Using Empower 3 Software and its Custom Calculations and Custom Reporting functions enables you to quickly and automatically evaluate chromatographic data. Configurable reports allow you to choose optimal conditions based on metrics rather than judgment, ensuring a comprehensive assessment of data and best method conditions.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_Arc_System_7_e7ef959203.jpg" alt="Waters ACQUITY Arc System: Method transfer of USP Assay for Fluconazole using the ACQUITY Arc System. Here the peak has same m/z of a related compound. Conditions: Mobile phase: 20:80 acetonitrile/ water; Flow rate = 0.5 mL/min; Column: XSelect HSS T3, 4.6 x 150 mm, 3.5 μm; UV@ 260 nm; 20.0 μL injection volume." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_Arc_System_7_e7ef959203.jpg 224w," sizes="100vw" width="939" height="654"></p><h3><strong>Streamline your workflow</strong></h3><div><div data-message-author-role="assistant" data-message-id="7b732be9-0a45-45fb-b585-70a90c1a74d6" dir="auto" data-message-model-slug="gpt-4o"><div><div><p data-start="602" data-end="827">How would you benefit from increased assay consistency between analysts and from lab to lab? What would you gain by accelerating your robustness testing prior to transferring methods to QA/QC?</p><p data-start="829" data-end="1392" data-is-last-node="">Auto•Blend Plus Technology is a novel software tool that extends traditional quaternary solvent blending to permit gradient programming directly in units of pH and ionic strength, providing the ability to vary composition in even the smallest increments of pH (even those differing by 0.1 pH units or less).&nbsp;</p><p data-start="829" data-end="1392" data-is-last-node="">With Auto•Blend Plus, the cumbersome and error-prone approach of manually preparing several pre-mixed mobile phases can now be eliminated with on-demand mobile phase creation, providing significant time savings and improved productivity to the laboratory.</p></div></div></div></div>

Waters Alliance HPLC System

 With its proven performance history, the Alliance HPLC is the industry’s analytical HPLC system of choice, ideally suited for methods development and routine analysis.

<div><div><h4><strong>Reliably achieve quality, compliant data. Every time, in every lab.</strong></h4></div></div><div><div><p><strong>Liquid chromatography (LC) systems must deliver unequivocal results that give you confidence in your scientific and business decisions. Waters LC commitment continues to succeed with the latest Alliance HPLC System – trusted by scientists worldwide for the data to drive informed decisions.</strong></p><div><div><div><div><p>Building on <strong>industry-standard performance and reliability</strong>, the <strong>Alliance HPLC System</strong> provides the <strong>capabilities to meet today’s business challenges</strong>. With its <strong>proven performance history</strong>, the Alliance HPLC is the <strong>industry’s analytical HPLC system of choice</strong>, ideally suited for <strong>methods development and routine analysis</strong>.</p><ul><li>Time-tested, dependable, and robust workhorse for your HPLC separations</li><li>Integrated solvent and sample management with consistent system-to-system performance and high reproducibility</li><li>Simplify your daily LC system start-up with advanced software functionality</li></ul><h5><strong>Recommended Use</strong></h5><p>For standard HPLC workflows where <strong>consistency and compliance</strong> are the highest priorities.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_HPLC_System_1_6b63ab6d62/Waters-Alliance-HPLC-System-1.jpg" alt="Waters Alliance HPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_HPLC_System_1_6b63ab6d62/thumbnail_Waters-Alliance-HPLC-System-1.jpg 147w," sizes="100vw" width="908" height="961"></p><div><div><h3><strong>Excellence through the years</strong></h3><p>The consistency of the Alliance HPLC System gives you <strong>exceptional confidence in your analytical results</strong>, day-to-day and year-to-year. Get <strong>accurate and reproducible results</strong> with <strong>Waters flagship HPLC technology</strong>, which provides <strong>consistent and reliable performance</strong>. Whether your Alliance HPLC System is newly manufactured, or you're working on one that is several years old, the Alliance HPLC System is a <strong>time-tested, dependable,</strong> and <strong>robust </strong>workhorse for your HPLC separations.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_HPLC_System_dfafc334c1.jpg" alt="Waters Alliance HPLC System: Comparison of the separation of carbamates using two different Alliance HPLC Systems, manufactured 7 years apart. The results are equivalent." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_HPLC_System_dfafc334c1.jpg 245w," sizes="100vw" width="1024" height="532"></p></div></div><div><div><h3><strong>Performance that exceeds your method requirements</strong></h3><p>The <strong>Alliance HPLC System</strong> ensures the <strong>reliability of your results</strong> via <strong>high injection precision</strong> and <strong>repeatable and accurate flow rates</strong>, resulting in <strong>easy peak identification</strong>, <strong>precise quantification</strong>, and <strong>exceptional retention time repeatability</strong>.</p><p>The integrated solvent delivery system features <strong>quaternary blending with a fixed delay volume</strong> for <strong>consistent and predictable results</strong>, regardless of system back pressure. The sample managers’ <strong>flexible injection capabilities</strong> cover a wide injection volume range (up to 2 mL) with <strong>excellent carryover performance</strong>, typically <strong>below 0.005%</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_HPLC_System_2_6dab43c365.jpg" alt="Waters Alliance HPLC System: USP method for Budesonide on the Alliance HPLC System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_HPLC_System_2_6dab43c365.jpg 245w," sizes="100vw" width="1024" height="580"></p></div></div><div><div><h3><strong>Advancements in column chemistry and mass detection</strong></h3><p>The <strong>Alliance HPLC</strong> can leverage <strong>smaller particle size column chemistry</strong> to improve your laboratory's efficiency. With <strong>CORTECS 2.7 µm particle size columns</strong>, your lab will benefit from <strong>improvements in resolution</strong> and <strong>faster run times</strong> when transferring from a 5 µm size particle chemistry.</p><p>Further <strong>increase confidence in your data</strong> by adding <strong>mass confirmation with the ACQUITY QDa Detector</strong>, which is <strong>simple to use</strong> and can easily integrate into your existing workflow. <strong>Analysis in Empower 3 Software</strong> combines data from <strong>UV/Vis and mass spectrometry (MS)</strong> peaks to give <strong>mass information to each peak</strong> in the separation.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_HPLC_System_3_3711671b2e.jpg" alt="Waters Alliance HPLC System: Mass detection with the ACQUITY QDa Detector with UV detection." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_HPLC_System_3_3711671b2e.jpg 245w," sizes="100vw" width="1024" height="550"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_HPLC_System_4_bf40981882.jpg" alt="Waters Alliance HPLC System: Mass detection with the ACQUITY QDa Detector with UV detection." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_HPLC_System_4_bf40981882.jpg 240w," sizes="100vw" width="1024" height="666"></p></div></div><div><div><h3><strong>Features and benefits</strong></h3><ul><li><strong>Quaternary solvent blending. </strong>Support isocratic and gradient applications with 11 unique gradient profile curves and blend up to 4 solvents in any proportion with Auto-Blend Technology. Compatible with solvent types such as reversed-phase, normal-phase, GPC, SEC, and IEX.</li><li><strong>Advanced solvent delivery capabilities. </strong>Serial flow path with pulse-free solvent delivery without the use of dampeners. Online solvent degassing and automated solvent compressibility compensation for accurate flow. Integrated seal wash for robust operation with all solvent types is standard.</li><li><strong>Optional, temperature-controlled environment.</strong> House up to 120 vials in an optional, temperature-controlled environment. Achieve low carryover with active and user programmable needle wash. Variable injection volumes from 0.1 to 100 μL standard, and up to 2 mL optional. Support STAT samples and auto-addition.</li><li><strong>Detection and column options. </strong>Get optional column heating, heating/cooling, or column switching capabilities. Detection capabilities include photodiode array, UV/Vis, fluorescence (FLR), refractive index (RI), evaporative light scattering (ELS), electrochemical, conductivity, and mass detection.</li><li><strong>Intuitive interface and software. </strong>Get instant access to system settings through the large LCD screen with simplified daily set-up with SystemPREP. Supports Empower, MassLynx, and 3<sup>rd</sup> party software packages.</li><li><strong>Compliance-ready. </strong>Supports Waters Empower-based automated system qualification tool (SQT), minimizing the time and cost of annual qualification with standards like GMP, GLP, ISO 17025, and USP &lt;1058&gt;.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_HPLC_System_2_47fe8951d2/Waters-Alliance-HPLC-System-2.jpg" alt="Waters Alliance HPLC System: Alliance HPLC System provides powerful functionality for all your application needs." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_HPLC_System_2_47fe8951d2/thumbnail_Waters-Alliance-HPLC-System-2.jpg 161w," sizes="100vw" width="903" height="874"></p><h3><strong>Specifications</strong></h3><ul><li><strong>Maximum operating pressure</strong>: 5,000 psi</li><li><strong>Front panel display</strong>: Easy to use control panel</li><li><strong>Mobile phases</strong>: Up to 4 with Auto-Blend Technology</li><li><strong>Flow rate range</strong>: Up to 10 mL/min</li><li><strong>Sample carryover</strong>: ≤0.0025% (Caffeine) under specified conditions</li><li><strong>Sample compartment</strong>: 4–40 °C</li><li><strong>Pump options</strong>: Quaternary</li><li><strong>Solvent conditioning</strong>: Vacuum Degas</li><li><strong>Column capacity</strong>: Standard up to 3 columns</li><li><strong>Maximum sample capacity</strong>: 120</li><li><strong>Detector options</strong>:&nbsp;<ul><li>Tunable UV</li><li>Photo Diode Array</li><li>Fluorescence</li><li>Refractive Index</li><li>Evaporative Light Scattering</li><li>Electrochemical</li><li>Conductivity</li><li>Mass Spectrometry</li></ul></li><li><strong>External control</strong>:&nbsp;<ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/627">Empower Software</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/635">MassLynx Software</a></li></ul></li><li><strong>Physical specifications</strong>:<ul><li><strong>Width:</strong> 45.7 cm (18.0 in.) or 58.4 cm (23.0 in.) with column heater</li><li><strong>Height:</strong> 57.1 cm (22.5 in.)</li><li><strong>Depth:</strong> 57.1 cm (22.5 in.) or 64.8 cm (25.5 in.) with sample heater/cooler</li></ul></li></ul></div></div></div></div></div></div></div></div>

Waters Charged Aerosol Detector (CAD)

Waters Charged Aerosol Detector (CAD) enables universal quantitation of non-volatile and semi-volatile compounds independent of UV activity, with wide dynamic range and seamless integration with Empower™ Software.

<h3><strong>Expand Your Detection Range with a Detector Purpose-Built for Empower™ Software</strong></h3><p>Empower™ Software–based laboratories require detection solutions that are easy to adopt, robust, and capable of accurately quantifying non-volatile and semi-volatile compounds—regardless of chemical structure or UV activity.<br>The <strong>Waters Charged Aerosol Detector (CAD)</strong> is purposefully engineered to meet these demands, delivering universal, reliable detection fully integrated with Waters chromatography systems and Empower™ or MassLynx™ Software.</p><p>With a wide dynamic range exceeding four orders of magnitude, the Waters CAD enables <strong>simultaneous quantitation of low-level, non-UV-active analytes</strong>, along with related impurities and excipients, in a single run—helping laboratories reduce method development time, increase productivity, and improve process control.</p><h4><strong>Key Benefits</strong></h4><ul><li><strong>Universal detection without UV limitations</strong><br>Detect and quantify non-volatile and semi-volatile compounds independent of chromophore presence.</li><li><strong>Wide dynamic range (&gt;4 orders of magnitude)</strong><br>Confidently quantify trace-level components and major constituents simultaneously.</li><li><strong>Purpose-built for Empower™ Software</strong><br>Seamless integration into regulated workflows with Empower-based qualification and long-term software compatibility.</li><li><strong>Compatible across Waters LC platforms</strong><br>Integrates easily with Alliance™, Arc™, ACQUITY™ Arc, ACQUITY™ H-Class, ACQUITY™ I-Class, and UPLC™ Systems.</li><li><strong>Designed for robustness and ease of use</strong><br>Optimized hardware, simplified maintenance, and enhanced system protection features minimize downtime.</li></ul><h4><strong>Technical Specifications</strong></h4><h5><strong>Detector Performance</strong></h5><ul><li><strong>Detector flow rate:</strong><br>0.010–2.000 mL/min</li><li><strong>Dynamic range:</strong><br>Greater than four orders of magnitude (four individual power values)</li><li><strong>Sampling rate:</strong><br>Up to 200 Hz</li><li><strong>Number of channels:</strong><br>Four (4), supported by four (4) independent background current channels</li></ul><h5><strong>Temperature Control</strong></h5><ul><li><strong>Evaporation temperature:</strong><ul><li>Ambient (off)</li><li>Controlled range: 10 °C to 100 °C (0.1 °C increments)</li><li>Minimum of 5 °C above ambient</li></ul></li></ul><h5><strong>Gas Requirements</strong></h5><ul><li><strong>Inert gas supply:</strong><br>Nitrogen (recommended) or compressed air</li><li><strong>Inlet pressure:</strong><br>4.83–5.52 bar<br>(483–552 kPa, 70.0–80.0 psi)</li><li><strong>Gas consumption:</strong><br>Typically ≤ 5 L/min</li></ul><h5><strong>Diagnostics and Monitoring</strong></h5><ul><li><strong>Diagnostic channels include:</strong><ul><li>Nebulizer gas flow and pressure (psi)</li><li>Evaporator temperature (°C)</li><li>Ion trap voltage (V)</li><li>Charger current (µA)</li><li>Mixing chamber temperature (°C)</li></ul></li></ul><h5><strong>Electrical and Physical Specifications</strong></h5><ul><li><strong>Power requirements:</strong><br>100–240 VAC</li><li><strong>Dimensions:</strong><ul><li>Width: 34.3 cm (13.5 in)</li><li>Height: 20.8 cm (8.2 in)</li><li>Depth: 61.0 cm (24.0 in)</li></ul></li><li><strong>Biocompatible:</strong><br>No</li></ul><h5><strong>Software and System Compatibility</strong></h5><ul><li>Optimized for <strong>Empower™ Software</strong> and <strong>MassLynx™ Software</strong> control</li><li>Robust chromatography data system (CDS) communications to minimize downtime</li><li>Backward compatibility to <strong>Empower™ 3 Feature Release 4 Service Release 3 (SR3)</strong></li><li>Fully compatible with systems qualification and validation requirements in regulated environments</li></ul><h5><strong>Seamless Method Transfer Across Laboratories</strong></h5><p>The Waters CAD is designed to simplify method transfer within organizations and across external laboratories. It maintains method simplicity while adding enhanced tools for equivalency and reproducibility, reducing the need for revalidation when transitioning from legacy or third-party CAD solutions.</p><p>The intuitive <strong>ACQUITY™ console control panel</strong> enables straightforward operation and simplifies replacement of outdated technology across laboratory networks.</p><h5><strong>Designed for Ease of Use and Reliability</strong></h5><ul><li>Single filter manifold with <strong>push/pull filter replacement</strong></li><li>Easy-to-replace nebulizer for improved serviceability</li><li>Intelligent divert valve automatically sends flow to waste if gas pressure is lost or system errors occur</li><li>Enhanced <strong>leak detection and flood protection</strong>, safeguarding instruments in the event of CDS communication loss</li></ul><h5><strong>Recommended Use</strong></h5><p><strong>Accurate quantitation in:</strong></p><ul><li>HPLC, UHPLC, and UPLC separations</li><li>Preparative and purification workflows</li><li>Pharmaceutical QC and R&amp;D</li><li>Analysis of excipients, lipids, sugars, surfactants, and non-UV-active impurities</li></ul>

Waters Arc Premier LC System

The Arc Premier System features new, innovative MaxPeak High Performance Surfaces (HPS) Technology, which effectively reduces non-specific adsorption due to metal interactions, without complicated mobile phases or laborious methods.

<div><div><h4><strong>See clearly and consistently, with confidence.</strong></h4></div></div><div><div><p><strong>Today’s scientists and lab managers need to confidently produce the most accurate, reliable, and reproducible data. The Arc Premier System produces correct, robust results from the very first injection, reliably and easily.&nbsp;</strong></p><p>The <strong>Arc Premier System</strong> features the new, innovative solution of <strong>MaxPeak High Performance Surfaces (HPS) Technology</strong>, which effectively reduces non-specific adsorption due to metal interaction — without complicated mobile phases or laborious methods. The <strong>Arc Premier System</strong> sharpens chromatographic peaks for <strong>metal-sensitive compounds</strong> by eliminating secondary interactions from metals, resulting in:</p><ul><li>Improved compliance from higher quality data</li><li>Faster, more reproducible, and accurate data integration</li><li>Shorter time from sample to result, without conditioning</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_6d7c95a93a.jpg" alt="Waters Arc Premier LC System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_6d7c95a93a.jpg 245w," sizes="100vw" width="1024" height="611"></p><p>With the Arc Premier System, we continue to deliver on the product quality you expect, combined with recent innovations in <strong>MaxPeak HPS Technolog</strong>y, to always deliver the<strong> best possible results</strong>.&nbsp;</p><p>Whether you are working to ensure the safety of a new and innovative product, maintain the consistency and supply of a current one, or test your food safety and quality, the Arc Premier System gives you<strong> greater data quality, flexibility, reproducibility, and faster data integration </strong>with right first-time results right out of the box, <strong>without the need for complicated mobile phases and laborious methods to prepare your system.</strong></p><div><div><div><div><div><div><ul><li><strong>MaxPeak HPS Technology</strong>, minimizing risk of metal-analyte interactions</li><li>Pressure envelope extends to <strong>9500 psi </strong>through a flow rate range of <strong>1–5 mL/min</strong>, providing an optimized pairing with column dimension and particle size</li><li><strong>Flexible quaternary and binary pumping options</strong></li><li>High performance analytical optical detectors, include photodiode array (PDA), UV/Vis, and fluorescence (FLR)</li><li>Mass detection options with the <strong>ACQUITY™ QDa™ Mass Detector</strong>,<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1543"> <strong>SQD2 Detector</strong></a>, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/209"><strong>Xevo™ TQ-S micro</strong></a>, and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/212"><strong>Xevo TQ-S cronos</strong></a></li><li>Flexible column manager options available for up to six columns ranging in length from <strong>50 mm to 300 mm</strong>, with a temperature range of <strong>4 °C to 90 °C</strong></li><li><strong>Auto•Blend Plus™ Technology</strong> for mobile phase reproducibility and <strong>Gradient SmartStart</strong> for method transfer</li><li>Wide range of trusted particle technologies in <strong>MaxPeak Premier Columns</strong></li><li>Compliance-ready<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/627"><strong>Empower™ Chromatography Data System</strong> </a>(CDS) delivering high quality data integrity</li><li>Automated quantification tools to minimize compliance costs and time</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_2_d1a922ae6d.jpg" alt="Waters Arc Premier LC System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_2_d1a922ae6d.jpg 245w," sizes="100vw" width="1024" height="585"></p></div></div><div><div><h3><strong>Flexible and Robust HPLC Designed for Your Development and Routine Testing Needs</strong></h3><ul><li><strong>Low dispersion HPLC: </strong>High performing HPLC with bandspread of &lt;30 μL for high chromatographic resolution.&nbsp;</li><li><p><strong>Versatile column management: </strong>Support for analytical LC column dimensions up to 300* mm with capacity to automatically select between as many as six analytical columns. Equipped with independently controlled temperature zone, active pre-heating, and<strong> eCord™ Intelligent Chip Technology </strong>for Waters columns.</p><p>* MaxPeak Premier Columns are recommended for use with the Arc Premier System and are currently only available in lengths up to 150 mm.</p></li><li><strong>Flow-through needle Injector: </strong>Volume range of 0.1 to 1000 μL and ultra-low carryover performance compatible with sensitive LC-MS applications.</li><li><strong>High Performance Surfaces Technology: </strong>With MaxPeak HPS Technology, analytes are impeded from Lewis acid-base interactions and adsorptive losses. This technology has proven to be effective in improving the analysis of electron-rich compounds, such as those containing phosphate and carboxylate groups.</li><li><strong>Consumables: </strong>Compatible with MaxPeak Premier Column chemistry to meet the needs of your reversed-phase and HILIC applications. Quality Control (QC) Reference Material benchmarks your Arc Premier System and enables perfect resolution. <strong>Certified clean </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/197"><strong>QuanRecovery™ vials</strong></a> to give full sample integrity.</li><li><strong>High performance analytical detectors : </strong>A wide range of high-performance detection capabilities, optimized with HPS, to support diverse applications. Includes photodiode array, UV/Vis, and fluorescence, with the additional option of single and triple quad mass detection.</li><li><strong>Solvent blending: </strong>Quaternary or binary solvent mixing. Delivers precise and accurate separations at pressures up to 9500 psi. Optional solvent select valve adds access to additional solvents. Automated solvent compressibility, integrated solvent degassing, and programmable seal wash maximize flow accuracy, precision, and reliability.</li><li><strong>Auto•Blend Plus Technology: </strong>Reduce human error and accelerate method robustness testing for chromatographic methods by programming gradients to control mobile phase pH and ionic strength.</li><li><strong>Gradient SmartStart: </strong>Adjust the injection relative to the gradient start to emulate other HPLC systems’ dwell volumes, without the need to alter the gradient table. Successfully transfer most methods in just two injections.</li><li><strong>Laboratory Informatics: </strong>Software control within your existing <strong>Empower </strong>or <strong>MassLynx™ </strong>infrastructure. Empower Method Validation Manager (MVM) allows you to perform chromatographic method validation in one application. Optional S-Matrix Fusion Software automates your method development according to AQbD guidelines.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_3_5db411b90a.jpg" alt="Waters Arc Premier LC System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_3_5db411b90a.jpg 234w," sizes="100vw" width="1024" height="682"></p></div></div></div></div><div><div><div><div><div><div><h3><strong>The Universal Platform for Liquid Chromatography</strong></h3><p>Non-specific adsorption of metal-sensitive compounds is an unpredictable challenge, resulting in chromatography with large relative standard deviations (RSDs) and broad, overlapping peaks, which can be challenging to integrate quickly and be accurate consistently.</p><p>Designed with MaxPeak HPS Technology and paired with <strong>MaxPeak Premier 2.5 μm Columns</strong>, the Arc Premier System improves data quality for challenging compounds, including metal-sensitive compounds tested with LC methods – so you can see clearly and consistently, with confidence.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_8_a4038daa52.jpg" alt="Waters Arc Premier LC System: Figure 1. Analysis of adenosine monophosphate, adenosine diphosphate, and adenosine triphosphate. Significant improvements to sensitivity and recovery are observed with the Arc Premier Solution compared to a conventional LC system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_8_a4038daa52.jpg 245w," sizes="100vw" width="1123" height="520"></p></div></div></div></div></div></div></div></div><div><div><h3><strong>Clear</strong></h3><p>Future-proof your lab for the next generation of challenging compounds with MaxPeak HPS Technology, which sharpenspeaks for metal-sensitive compounds, resulting in higher data quality and improved sensitivity with chromatographic reproducibility and precision.</p><p>Data quality and performance are <strong>critical </strong>for your lab, but those can’t come at the sacrifice of ruggedness and ease of use.&nbsp;</p><p>With MaxPeak HPS Technology and flexible LC performance, your lab gets the typical benefits of an LC system optimized for <strong>2.x μm column chemistry </strong>with the MaxPeak HPS Technology’s ability to shorten run times and achieve sharp peaks - no lengthy and complex conditioning and conditioning methodologies for metal-sensitive compounds required.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_9_34ec4befec.jpg" alt="Waters Arc Premier LC System: Figure 2. Analysis of adenosine triphosphate. Lower limits of detection and increased calibration curve linearity are demonstrated with the Arc Premier Solution compared to a conventional LC system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_9_34ec4befec.jpg 245w," sizes="100vw" width="940" height="523"></p></div></div><div><div><h3><strong>Consistent</strong></h3><p>Seeing your results more clearly than ever is critical, but those results must be consistent and error-free and your methods easily reproducible, so you can spend less time on analysis and ensure compliance.&nbsp;</p><p>By <strong>significantly sharpening peak shapes</strong> for metal-sensitive analytes, scientists report an improvement in %RSD when integrating data from metal-sensitive compounds on the Arc Premier System. Along with the improvement in data consistency users also report a decrease of time needed to integrate peaks by <strong>approximately 30%</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_f80500f8a4.jpg" alt="Waters Arc Premier LC System: Figure 3. Analysis of hydrocortisone phosphate, betamethasone phosphate, dexamethasone, and dexamethasone acetate. Peak heights increased and peak shapes are more symmetrical for metal- sensitive compounds on the Arc Premier Solution compared to a conventional LC system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_f80500f8a4.jpg 235w," sizes="100vw" width="1381" height="918"></p><p>The Arc Premier System <strong>eliminates </strong>the need for<strong> variability-prone conditioning and complex mobile phases</strong> – so you can minimize user errors, improve compliance, and reduce expensive audits from red flag-inducing conditioning injections.</p><p>Your organization needs to reliably migrate higher-quality methods between your systems for maximum reproducibility. With MaxPeak HPS Technology and flexible pump configurations, your lab can easily, reliably <strong>migrate methods between MaxPeak HPS-based systems </strong>quickly, saving you time and money from unnecessary rework. You can also<strong> migrate methods from non-MaxPeak HPS-enabled systems </strong>safely, as method performance of non-metal-sensitive compounds have been shown to not be adversely affected.</p><p>Combining higher data quality with ease of use for your analysts and seamless method transfer, enables results that can be generated consistently between runs and with various analysts.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_6_5332aab31f.jpg" alt="Waters Arc Premier LC System: Figure 4. Analysis of hydrocortisone phosphate, betamethasone phosphate, dexamethasone, and dexamethasone acetate. A zoom in on the baseline shows improved peak shapes and resolution for metal-sensitive compounds on the Arc Premier Solution compared to a conventional LC system, improving baseline resolution." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_6_5332aab31f.jpg 229w," sizes="100vw" width="1380" height="942"></p><h3><strong>Confident</strong></h3><p><strong>Reducing analytical uncertainty and achieving peace</strong> of mind are important for your organization. With MaxPeak HPS Technology, metal-sensitive analytes become visible that were previously undetectable. This allows you to quickly and confidently know that you’ve seen everything in your sample, giving you the confidence to stand behind your data-driven decisions.</p><p>The <strong>combination of MaxPeak HPS Technology, flexible pump and column management options, and precise optical and MS detection</strong> give you the method development and verification capabilities to know that no matter the sample - you can deliver a robust method you can stand behind.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_2_85f2f7cc29.jpg" alt="Waters Arc Premier LC System: Figure 5. Analysis of data of hydrocortisone phosphate, betamethasone phosphate, dexamethasone, and dexamethasone acetate from an Arc Premier System and a conventional LC system by six users. Peak area reproducibility improved 9 – 124x when integrating the same data from metal-sensitive compounds across six users." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_2_85f2f7cc29.jpg 239w," sizes="100vw" width="1243" height="810"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_5_514749f32d.jpg" alt="Waters Arc Premier LC System: Figure 6. Analysis of acetaminophen, caffeine, leucine enkephalin, sulfadimethoxine, amitriptyline, reserpine, and terfenadine shows that non-metal-sensitive compounds demonstrate comparable performance between the Arc Premier Solution and conventional LC systems." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_5_514749f32d.jpg 245w," sizes="100vw" width="1242" height="735"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_7_edc8ecaa93.jpg" alt="Waters Arc Premier LC System: Figure 7. Comparison of adenosine triphosphate and adenosine diphosphate peaks using a conventional LC system and the Arc Premier Solution over 120 injections. The peak areas of metal-sensitive compounds remain constant from the first to the 120th injection using the Arc Premier Solution. Peak areas of metal-sensitive compounds on a conventional LC system continuously increase over time and do not stabilize even after 120 injections." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_7_edc8ecaa93.jpg 218w," sizes="100vw" width="1038" height="744"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_3_f1cca337bc.jpg" alt="Waters Arc Premier LC System: Figure 8. Comparison of adenosine triphosphate and adenosine diphosphate peaks using a conventional LC system and the Arc Premier Solution over 120 injections. The peak areas of metal-sensitive compounds remain constant from the first to the 120th injection using the Arc Premier Solution showing less than a 1% change in peak area for all compounds. Peak areas of metal-sensitive compounds on a conventional LC system show an increase of 2–35% when compared to the first injection and show no signs of stabilization." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_3_f1cca337bc.jpg 216w," sizes="100vw" width="1039" height="750"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_4_1dae3909ae.jpg" alt="Waters Arc Premier LC System: Figure 9. Adenosine triphosphate, adenosine diphosphate, adenosine monophosphate, and adenosine stability using the Arc Premier Solution over 1000 injections. The peak areas of metal-sensitive compounds remain consistent over 1000 injection using the Arc Premier Solution demonstrating the robustness of the system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_4_1dae3909ae.jpg 243w," sizes="100vw" width="1040" height="669"></p></div></div></div></div>

Waters Alliance iS HPLC System

Waters™ delivers a reliable partner for QC labs. The Alliance™ iS HPLC System enhances efficiency, reduces errors, and simplifies workflows - your new essential lab ally.

<h3><strong>The Alliance iS HPLC System didn’t start in our lab.</strong></h3><p class="cke-user_style-important"><strong>It started in yours.</strong></p><p><strong>Pharmaceutical Quality Control (QC)</strong> labs face relentless demand to <strong>do more with less</strong> amid higher staff turnover, growing levels of sample complexity, and the drive to reduce errors.</p><p>With regulatory scrutiny and faster time to market fueling these intense demands, the need for <strong>simplicity has never been greater</strong>.</p><p>Waters™ understands the challenges you face and is ready to deliver a true ally for your laboratory. With capabilities developed specifically for the QC laboratory, the <strong>Alliance™ iS HPLC System</strong> will quickly become your favorite ally.</p><ul style="list-style-type:disc;"><li>Intuitively prevents up to 40% of common errors*</li><li>Provides fast, simple guidance at the point of need</li><li>Boosts productivity and capacity through effective resource utilization and error-free operation</li><li>Drives workflow efficiencies and quality improvements</li><li>Improves data integrity</li></ul><p>*Based on Waters’ market research in 2022, surveying 56 global Pharma QC labs running &gt;25 systems</p><h3><strong>Common challenges facing the QC lab</strong></h3><p class="cke-user_style-important"><strong>What you are telling us</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_i_S_HPLC_System_cc30c5f925.jpg" alt="Waters Alliance iS HPLC System - What you are telling us" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_i_S_HPLC_System_cc30c5f925.jpg 245w," sizes="100vw" width="2038" height="1132"></p><h3><strong>Meet your new lab ally</strong></h3><p>Intuitive and reliable, the <strong>Alliance iS HPLC System</strong> is designed to work seamlessly with <strong>Empower™ Software</strong> and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/720007883en_41b7055d98/720007883en.pdf"><strong>eConnect™ Column Tag Technology</strong></a>, unlocking unique features and functionality that eliminate the need to choose between simplicity, efficiency, and quality.</p><h3><strong>Step-change the performance of your lab</strong></h3><p class="cke-user_style-important"><strong>Achieve First Time Quality (FTQ) with the Alliance iS HPLC System</strong></p><p>The <strong>Alliance iS HPLC System</strong> supports FTQ by reducing the risk of common errors and improving the reliability of analytical measurements. Your lab can <strong>reduce reagents and consumables waste</strong>, and automated system checks help to meet critical error reduction KPIs. The increase in operational efficiency and productivity will save time and money and boost the capacity of your lab.**</p><p>With ease of use at the heart of the user experience, the <strong>Alliance iS HPLC System</strong> identifies potential errors earlier, reducing the number of retests and failure investigations. This supports a Quality culture resulting not only in safer products critical to human health and well-being, but also an improved working environment, directly impacting employee retention and motivation.**</p><p>**vs the Alliance HPLC System</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_i_S_HPLC_System_2_44577b6737.jpg" alt="Waters Alliance iS HPLC System with bottles connected." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_i_S_HPLC_System_2_44577b6737.jpg 234w," sizes="100vw" width="1024" height="682"></p><h3><strong>The System: intuitively simple</strong></h3><h5><strong>System Status Lighting and Solvent Tubing Clips&nbsp;</strong></h5><p>Status lighting provides you with a clear visual indication of the system status (in use, idle etc), while the color-coded solvent tubing clips ensure the tubing remains organized to enable tracing from instrument to the solvent bottle flags.</p><h5><strong>Made for Empower</strong></h5><p><strong>Waters Empower Software Suite</strong> helps your entire laboratory operate better, with the industry’s most advanced data acquisition, management, processing, analytics, and reporting capabilities. Empower Software provides you an environment where your records are traceable, so you always have full control of your most critical asset - your data.</p><h5><strong>waters_connect™ System Monitoring&nbsp;</strong></h5><p>Maximize lab productivity - utilize resources more effectively with real-time lab management from anywhere, anytime. System Monitoring provides intuitive and centralized access to detailed Empower Software instrument information via the waters_connect Cloud Platform, without compromising security or compliance.</p><h5><strong>Intelligent Method Translator App&nbsp;</strong></h5><p>Working with Empower Software, the iMTA enables you to create an Alliance iS HPLC System Instrument Method directly from a Waters or other third-party LC system. Basic chromatographic conditions are automatically transferred for you, and the new Empower instrument method can be reported, providing traceability to the original method for compliance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_i_S_HPLC_System_with_bottles_connected_and_the_doors_open_ff4184918a.jpg" alt="Waters Alliance iS HPLC System with bottles connected and the doors open." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_i_S_HPLC_System_with_bottles_connected_and_the_doors_open_ff4184918a.jpg 234w," sizes="100vw" width="1024" height="682"></p><h3><strong>Say ‘hi’ to your lab ally</strong></h3><h5><strong>Intuitive touchscreen&nbsp;</strong></h5><p>An easy-to-use, advanced touchscreen integrates with Empower Software and provides easy-to-follow steps. Pre-run checks for common errors such as missing vials, incorrect column, and qualification/preventative maintenance requirements enable you to catch these mistakes before they result in a sample analysis failure, preventing re-runs.</p><h5><strong>Help at your fingertips&nbsp;</strong></h5><p>The Alliance iS HPLC System support journey delivers smart on-board technology that digitally brings you straight to the information you need at the new Waters Help Center. Train and troubleshoot with ease, knowing that Waters will support you at every stage.</p><h5><strong>Smart column capabilities&nbsp;</strong></h5><p>Ensure complete column traceability and facilitate post-run troubleshooting with the eConnect HPLC Columns. Ready-to-use from the box, eConnect columns are securely fitted with an NFC-enabled eConnect device tag, ensuring they are always automatically identified, verified, and tracked by the system. These second-generation smart columns propel today’s QC laboratory toward an entirely digital platform and away from manual logbooks.</p><h3><strong>Enjoy stress-free analysis</strong></h3><p>The Alliance iS HPLC System keeps you and your lab stress-free and running smoothly with an intuitive touchscreen that supports the productivity and efficiency of your lab.</p><ul><li>Start your day easily with a system guided start-up.</li><li>Pre-run checks to minimize sample analysis failures due to human error.</li><li>When issues arise, Alliance iS HPLC System provides you with information about what needs attention.</li><li>Guided workflows provide step-by-step guidance on how to resolve common issues.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_i_S_HPLC_System_2_0e64835283.jpg" alt="Waters Alliance iS HPLC System - Enjoy stress-free analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_i_S_HPLC_System_2_0e64835283.jpg 204w," sizes="100vw" width="1388" height="1063"></p><h3><strong>Built to perform, time after time</strong></h3><h4><strong>Intuitive innovation</strong></h4><p>Developed with the singular goal of providing innovation that solves the problems that matter in the QC lab, the Alliance iS HPLC System includes a range of new and unique features.&nbsp;</p><ul><li>New electronics to enable the Alliance iS HPLC System smart features (including advanced touchscreen, eConnect Column Tag Technology, and unparalleled interactivity with Empower Software)</li><li>Redesigned check valves and mixer for increased performance and robustness</li><li>Faster detector warm-up time and reduced drift to ensure you’re up and running quickly, for as long as your analysis requires</li><li>Robust performance when operating at the extremes of the Column Heater Cooler and Sample Manager temperature ranges</li><li>Class leading carryover performance and injection precision</li></ul><figure class="image"><img style="aspect-ratio:1561/740;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_i_S_HPLC_System_3_9aab20fd13.jpg" alt="Waters Alliance iS HPLC System - Overlay of 42 injections of gradient performance mix over 44 hours demonstrated RT repeatability of 0.5% RSD on the Alliance iS HPLC System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_i_S_HPLC_System_3_9aab20fd13.jpg 245w," sizes="100vw" width="1561" height="740"></figure><h3><strong>Alliance iS HPLC System gives you so much more</strong></h3><p class="cke-user_style-important"><strong>Unlock new potential with Empower Software</strong></p><p><strong>The Alliance iS HPLC System works exclusively with our </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/720008057en_af76145fe7/720008057en.pdf"><strong>Empower Software</strong></a><strong> version 3 Feature Release 4 </strong>or later, with fully enabled and differentiated features, starting with eConnect Technology. Empower Software elevates your quality, your business, and your lab.</p><ul style="list-style-type:disc;"><li>Intuitive method matching</li><li>Bi-directional touchscreen interactivity</li><li>Column tracking and history</li><li>Enhanced instrument traceability</li><li>Pre-run checks</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_i_S_HPLC_System_4_430a084194.jpg" alt="Waters Alliance iS HPLC System gives you so much more." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_i_S_HPLC_System_4_430a084194.jpg 245w," sizes="100vw" width="1385" height="674"></p><h3><strong>Help at your fingertips</strong></h3><p class="cke-user_style-important"><strong>From onscreen to onsite, we’re there for you.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Alliance_i_S_HPLC_System_5_df4f1467ed.jpg" alt="Waters Alliance iS HPLC System - From onscreen to onsite, we’re there for you." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Alliance_i_S_HPLC_System_5_df4f1467ed.jpg 245w," sizes="100vw" width="1550" height="910"></p><p>Maintain peak performance, minimize unexpected downtime, and ensure regulatory compliance of your AllianceTM iS HPLC System by partnering with Waters Service. Waters FlexCHOICETM Full-Service Plan for Regulated Laboratories includes:</p><ul style="list-style-type:disc;"><li>Yearly Waters Performance Maintenance</li><li>Priority* remote and onsite service including all parts, labor and travel</li><li>Full suite of compliance services</li><li>Discounts on future hardware upgrades and user training</li><li>Optional coverage available:<ul><li>Additional Performance Maintenance visits</li><li>Two business day on-site response time**</li></ul></li></ul><p>Priority over non-contract customers **May not be available in all areas</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_The_first_system_designed_for_Empower_the_Alliance_i_S_HPLC_System_features_intuitive_simplicity_built_specifically_for_QC_laboratories_112259fad6.jpg" alt="Waters Alliance iS HPLC System - The first system designed for Empower, the Alliance iS HPLC System features intuitive simplicity built specifically for QC laboratories." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_The_first_system_designed_for_Empower_the_Alliance_i_S_HPLC_System_features_intuitive_simplicity_built_specifically_for_QC_laboratories_112259fad6.jpg 234w," sizes="100vw" width="1024" height="682"></p>

Products focused on HPLC - page 1

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