LCMS webinars focusing on 2D-LC | LabRulez LCMS

Explore cutting-edge methodology for online protein removal and characterization of polysorbates and poloxamer in monoclonal antibody formulations.

In this webinar, our speakers will present the concept, different approaches for technical realization, and industrial applications of 2D-LC in polymer separations.

Analysis of a mAB with a HIC first dimension followed by a RP/desalting column in the second dimension.

In the first dimension the separation is by degree of ethoxylation, while in the second dimension by the separation occurs by the length of the hydrophobic tail.

The presentation will introduce the concept of 2-dimensional chromatography, the instrumental setup as well as typical applications.

Get an overview of 2D-LC instrumentation for multi-heart cutting and comprehensive 2D-LC.

Learn about the four modes of 2D-LC: heart-cutting, multiple heart-cutting, selective and full comprehensive, and find out how they relate conceptually.

Techniques for tackling more challenging complex samples. Understand the potential of advanced polymer separation. Advanced detection techniques, GPEC, RPLC, 2D LC.

Several concepts of the different types of 2D-LC will be explained to enable comprehensive understanding of this well- established technology.

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