This week we bring you application notes by Agilent Technologies, Shimadzu, Thermo Fisher Scientific and Waters Corporation!
We, 28.1.2026
LabRulez
Scientific article | Science and research
Coupling Liquid Chromatography to Orbitrap Isotope Ratio Mass Spectrometry: Overcoming Isotope Effects of Chromatography and Amount-Dependency by Peak Homogenization
This study couples LC to ESI-Orbitrap MS for stable isotope analysis using peak homogenization to remove chromatographic isotope effects and amount dependency, achieving precise C, N, and S isotopologue ratios.
This week we bring you application notes by Agilent Technologies, Shimadzu, Waters Corporation and poster by Thermo Fisher Scientific!
We, 21.1.2026
LabRulez
Scientific article | Science and research
Biochemometric 2D NMR-Based Heterocovariance Analysis: A Targeted Approach for Identifying Bioactive Compounds in Complex Mixtures
This study introduces a biochemometric 2D NMR heterocovariance approach to correlate spectral features with bioactivity, enabling targeted discovery of bioactive compounds in complex extracts.
Mo, 19.1.2026
LabRulez
Scientific article | Science and research
Implementation of Infrared-Activated Negative Electron Transfer Dissociation (IR-NETD) Using Xenon on a Quadrupole-Orbitrap-Quadrupole Linear Ion Trap Mass Spectrometer
This study reports the first implementation of IR-activated NETD with xenon on a quadrupole-Orbitrap MS, demonstrating improved RNA fragmentation and biopharmaceutical characterization.
This week we bring you application notes by Agilent Technologies, Shimadzu, Waters Corporation and poster by Thermo Fisher Scientific / HPLC!
We, 14.1.2026
LabRulez
Scientific article | Science and research
Structural Characterization and Multiomics Analysis Reveal Extensive Diversity and Global Distribution of Kurstakin Lipopeptides
This study combines metabolomics, structural analysis, and public omics data to uncover the extensive diversity and global distribution of kurstakin lipopeptides linked to Bacillus biocontrol activity.