Optimization of Methodology for Simultaneous Quantification of Trigonelline, 5-Caffeoylquinic Acid, and Caffeine in Green and Roasted Coffee Extracts by HPLC
A fast HPLC-UV method was optimized to quantify trigonelline, 5-CQA, and caffeine in multiple Arabica cultivars. The method proved robust and highlighted major cultivar and roasting-related changes.
Mo, 1.12.2025
LabRulez
Article | Webinars
Webinars LabRulezLCMS Week 49/2025
12 webinars: Andrew+ Robot, Chromeleon, DLS, field flow fractionation, GLP-1 analysis, green chemistry RNA, IRMS, Karl Fischer, lipidomics, metabolomics, nanocarriers, oligonucleotides, PFAS, proteomics, SEC
Mo, 1.12.2025
LabRulez
Article | Application
News from LabRulezLCMS Library - Week 48, 2025
This week we bring you application notes by Agilent Technologies, Shimadzu and Waters Corporation and poster by Thermo Fisher Scientific / HPLC!
We, 26.11.2025
LabRulez
Scientific article | Science and research
Visible-Light-Driven Photoactivity of Copper/PVA Composite Films against Murine Coronavirus
Copper/PVA films showed strong visible-light antiviral activity against MHV-3. Films with copper microparticles reduced viral load by 43% under illumination, compared with minimal reduction in the dark.
Mo, 24.11.2025
LabRulez
Scientific article | Science and research
Metabolomic Changes in Rice (Oryza sativa L.) Subjected to Herbicide Application through HPLC-HRMS and Chemometrics Approaches
HPLC-HRMS with chemometrics showed clear metabolomic changes in herbicide-treated rice, including reduced sugars, lower flavonoids, and disrupted phenylpropanoid pathways.
Quantifying Citrate Surface Ligands on Iron Oxide Nanoparticles with TGA, CHN Analysis, NMR, and RP-HPLC with UV Detection
This study presents a multimethod strategy to quantify citrate ligands on iron oxide nanoparticles using TGA, CHN, qNMR, and RP-HPLC, showing how selective methods improve accuracy and prevent overestimation.
Mo, 17.11.2025
LabRulez
Article | Application
News from LabRulezLCMS Library - Week 46, 2025
This week we bring you application notes by Agilent Technologies, Shimadzu and Waters Corporation and poster by Thermo Fisher Scientific!