Configuring and Navigating Chromatogram Window NIST26
Article | Academy

Configuring and Navigating Chromatogram Window NIST26

Learn how to configure, customize, and navigate the new NIST 26 Chromatogram Window. This practical guide covers layouts, zooming, filtering, structure display, and efficient data review workflows.
Tu, 26.5.2026
James Little/Mass Spec Interpretation Services
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Configuring and Navigating Chromatogram Window NIST26
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Elemental Composition with Freestyle)
Article | Video

Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Elemental Composition with Freestyle)

This course shows how to identify unknowns in LCMS analysis employing the NIST MSMS search software. Part 5 discusses the the determination of molecular formulae with Thermo Freestyle software.
Th, 10.4.2025
James Little/Mass Spec Interpretation Services
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Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Elemental Composition with Freestyle)
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Setting Up NIST Search and Freestyle Parameters)
Article | Video

Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Setting Up NIST Search and Freestyle Parameters)

This course shows how to identify unknowns in LCMS analysis employing the NIST MSMS search software. Part 3 discusses basic settings for Thermo Freestyle software and the NIST 2023 Search.
Th, 3.4.2025
James Little/Mass Spec Interpretation Services
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Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Setting Up NIST Search and Freestyle Parameters)
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Alternative "Less Efficient" Approaches)
Article | Video

Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Alternative "Less Efficient" Approaches)

This course shows how to identify unknowns in LCMS analysis employing the NIST MSMS search software. Part 2 discusses the alternate methods for processing the data.
Th, 27.3.2025
James Little/Mass Spec Interpretation Services
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Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Alternative "Less Efficient" Approaches)
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (“Nearby Precursors” Enhancement)
Article | Video

Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (“Nearby Precursors” Enhancement)

Part 1A discusses the using the "Nearby Precursor" to easily display a MSMS spectrum associated with an ion in MS.
Th, 20.3.2025
James Little/Mass Spec Interpretation Services
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Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (“Nearby Precursors” Enhancement)
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (NIST Search Type Demonstration)
Article | Video

Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (NIST Search Type Demonstration)

This course shows how to identify unknowns in LCMS analysis by the NIST MSMS search software. Part 4 demonstrates 3 different type searches for MSMS data within the NIST2023 search software.
Fr, 14.3.2025
James Little/Mass Spec Interpretation Services
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Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (NIST Search Type Demonstration)
 Data Processing for NIST MSMS Search Using Thermo Freestyle Software (My Favorite Approach)
Article | Video

Data Processing for NIST MSMS Search Using Thermo Freestyle Software (My Favorite Approach)

This part discusses my favorite approach for processing Orbitrap LCMS/LCMSMS data for identificaiton of unknowns using the NIST2023 search and associated libraries.
Th, 6.2.2025
James Little/Mass Spec Interpretation Services
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 Data Processing for NIST MSMS Search Using Thermo Freestyle Software (My Favorite Approach)
Using NIST MS Search with Agilent OpenLab Software for Unknown Identifications
Article | Academy

Using NIST MS Search with Agilent OpenLab Software for Unknown Identifications

Agilent’s OpenLab Software can easily be employed with NIST 2023 Search and associated libraries for unknown identifications.
Th, 23.1.2025
James Little/Mass Spec Interpretation Services
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Using NIST MS Search with Agilent OpenLab Software for Unknown Identifications
Using Agilent MassHunter to Perform NIST MSMS Search
Article | Video

Using Agilent MassHunter to Perform NIST MSMS Search

This web page demonstrates the use of the Agilent MassHunter Software for processing MSMS data files.  The MSMS spectra are easily sent to the NIST MSMS Search program for identification.
Th, 17.10.2024
James Little/Mass Spec Interpretation Services
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Using Agilent MassHunter to Perform NIST MSMS Search
Changes in Tandem (MS/MS) NIST23 Search Program (V3.0)
Article | Academy

Changes in Tandem (MS/MS) NIST23 Search Program (V3.0)

NIST2023 Library and Software Available in Early June. Many very significant improvements in the new version compared to 2020 version..
Fr, 26.5.2023
James Little/Mass Spec Interpretation Services
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Changes in Tandem (MS/MS) NIST23 Search Program (V3.0)
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