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Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets
Scientific article | Science and research

Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets

This study aimed to develop and compare ten extraction protocols to find the most effective method for generating metabolomics, lipidomics, and proteomics data from postmortem tissue.
Mo, 30.6.2025
LabRulez
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Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets
A novel LC-MS/MS assay for low concentrations of creatinine in sweat and saliva to validate biosensors for continuous monitoring of renal function
Scientific article | Science and research

A novel LC-MS/MS assay for low concentrations of creatinine in sweat and saliva to validate biosensors for continuous monitoring of renal function

This study develops and validates an LC-MS/MS assay to quantify low creatinine levels in sweat and saliva, supporting non-invasive biosensor-based kidney function monitoring during haemodialysis.
Mo, 19.5.2025
LabRulez
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A novel LC-MS/MS assay for low concentrations of creatinine in sweat and saliva to validate biosensors for continuous monitoring of renal function
News from LabRulezLCMS Library - Week 17, 2025
Article | Application

News from LabRulezLCMS Library - Week 17, 2025

This week we bring you application notes by Shimadzu and Waters Corporation, presentation by Agilent Technologies and technical notes by Knauer and Thermo Fisher Scientific!
We, 23.4.2025
LabRulez
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News from LabRulezLCMS Library - Week 17, 2025
Ion exchange chromatography of biotherapeutics: Fundamental principles and advanced approaches
Scientific article | Science and research

Ion exchange chromatography of biotherapeutics: Fundamental principles and advanced approaches

This review outlines IEX fundamentals and explores advanced strategies—like pH gradients, ultra-short columns, and coupling with MS—for characterizing complex biotherapeutics.
Mo, 21.4.2025
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Ion exchange chromatography of biotherapeutics: Fundamental principles and advanced approaches
Waters HPLC Column Coach
Article | Product

Waters HPLC Column Coach

Waters Column Coach is a helpful tool for comparing reversed-phase column selectivity. It uses the Neue Test to assess hydrophobicity and selectivity under consistent, standard conditions.
Th, 17.4.2025
Waters Corporation (Europe)
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Waters HPLC Column Coach
News from LabRulezLCMS Library - Week 16, 2025
Article | Application

News from LabRulezLCMS Library - Week 16, 2025

This week we bring you application notes by Agilent Technologies, Knauer, Shimadzu, Thermo Fisher Scientific and Waters Corporation!
We, 16.4.2025
LabRulez
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News from LabRulezLCMS Library - Week 16, 2025
News from LabRulezLCMS Library - Week 15, 2025
Article | Application

News from LabRulezLCMS Library - Week 15, 2025

This week we bring you application notes by Agilent Technologies, Shimadzu, Thermo Fisher Scientific and Waters Corporation!
We, 9.4.2025
LabRulez
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News from LabRulezLCMS Library - Week 15, 2025
Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics
Scientific article | Science and research

Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics

This study evaluates matrix effects in untargeted HILIC-MS plasma metabolomics using post-column infusion, identifying optimal conditions and improving method reliability for metabolite analysis.
Mo, 7.4.2025
LabRulez
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Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics
News from LabRulezLCMS Library - Week 14, 2025
Article | Application

News from LabRulezLCMS Library - Week 14, 2025

This week we bring you application notes by Agilent Technologies, Mestrelab Research, Shimadzu and Waters Corporation, poster by GC Image / MDCW and technical note by Thermo Fisher Scientific!
We, 2.4.2025
LabRulez
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News from LabRulezLCMS Library - Week 14, 2025
Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS
Scientific article | Science and research

Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS

This study presents an HPLC-ICP-MS method for precise quantification of Gd complexes in Gadoquatrane, enabling detection of trace by-products to optimize synthesis and drug control strategies.
Mo, 17.3.2025
LabRulez
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Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS
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LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike