This study demonstrates Orbitrap-IRMS for full and intramolecular carbon isotope analysis of PFOA, enabling sensitive PFAS source fingerprinting without analyte decomposition.

A coumarin-based photocleavable solid support allows visible-light release and nonchromatographic purification of RNA oligonucleotides, including UV-sensitive phosphorothioate backbones.

Gunacins, new compounds from Exobasidium, display strong anti-Leishmania and anti-Trypanosoma effects and also show antibacterial and antifungal activity.

A fast HPLC-UV method was optimized to quantify trigonelline, 5-CQA, and caffeine in multiple Arabica cultivars. The method proved robust and highlighted major cultivar and roasting-related changes.

Day 1 in České Budějovice featured an Orbitrap plenary by Alexander Makarov, sessions on exposome, proteomics and structural MS, sponsor talks, flash talks and an evening networking reception.

Explore how nitrogen blowdown enhances sample prep efficiency in SPE workflows using Waters Oasis, Agilent Bond Elut and Phenomenex Strata, improving analyte recovery, sensitivity and method reliability.

Explore global LCMS events in 2025: conferences, courses, workshops, and training. Stay updated on cutting-edge LC/MS methods and connect with experts worldwide.

A ZenoTOF 7600 modified for CID, EAD, and UVPD allowed LC–MS screening of pesticides in juices and wines. About 30 were detected at pg–ng/mL levels, confirmed by multiple dissociation methods.

A UHPLC-MS/MS assay using surrogate calibration and DMIS derivatization quantifies endogenous steroids and contraceptives in plasma with pg/mL sensitivity and regulatory-aligned validation.

The study examines treated wastewater from Arctic cruise ships to identify pharmaceuticals and other contaminants, highlighting potential risks to sensitive polar marine environments.