Stricter temperature control with HPLC-CAD can significantly improve the accuracy of semi-volatile analyte quantitation. Learn how Temperature Coupling Mode enhances sensitivity and predictability.

Phospholipids in serum and plasma can cause ion suppression, reduced MS sensitivity, and shorter column lifetime. Learn why phospholipid removal is critical for reliable LC-MS analysis.

A structured guide to chromatogram integration in Clarity software, explaining global and local integration parameters, peak detection, baseline handling, and transferring integration into analytical methods.

Wiley expands its IR, Raman, LC-MS, and SmartSpectra libraries to over 9.5 million spectra, delivering broader compound coverage and faster, more confident identification across analytical workflows.

Modern LC-MS workflows generate massive datasets that challenge traditional data transfers. WAN acceleration and cloud-native streaming enable secure, scalable data movement.

How can neutral analytes be efficiently concentrated in the presence of ionized acidic or basic contaminants? This SPE tip explains how mixed-mode cartridges improve selectivity and cleanup.

Discover how the Orbitrap Ascend BioPharma Tribrid MS enables comprehensive characterization of complex biotherapeutics, from ADCs and PTMs to oligonucleotides and RNA therapies.

A clear overview of the Instrument Window in Clarity Chromatography Software, explaining interface layout, workflow icons, analysis control, chromatogram handling, and calibration.

Organomation explains how PFAS-free nitrogen evaporators eliminate fluoropolymer contamination by replacing PTFE tape with a PTFE-free sealant, ensuring safe and reliable PFAS sample preparation.

Practical guide to oligonucleotide sample preparation using SPE. Learn how to optimize wash and elution steps for clean extracts and reliable LC-MS bioanalysis.