Cracking the Code of PEGylated Proteins: How Advanced Mass Spectrometry Reveals What’s Really Attached
Article | Science and research

Cracking the Code of PEGylated Proteins: How Advanced Mass Spectrometry Reveals What’s Really Attached

Discover how Orbitrap Charge Detection MS and a multi-enzyme workflow characterize PEGylated therapeutic proteins by determining PEG stoichiometry, mapping attachment sites, and detecting impurities.
Tu, 21.7.2026
Thermo Fisher Scientific
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Cracking the Code of PEGylated Proteins: How Advanced Mass Spectrometry Reveals What’s Really Attached
Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry
Scientific article | Science and research

Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry

This study introduces an HDX-MS titration workflow for quantifying protein–ligand affinities at global, peptide, and residue resolution.
Mo, 20.7.2026
LabRulez
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Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry
Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach
Scientific article | Science and research

Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach

This study uses temperature-controlled IM-MS to monitor protein unfolding and oligomer formation in real time, revealing early aggregation pathways.
Mo, 13.7.2026
LabRulez
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Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach
CEITEC Technology Will Help Reveal How Oxygen Controls Embryo Development
Article | Science and research

CEITEC Technology Will Help Reveal How Oxygen Controls Embryo Development

Scientists from CEITEC Brno University of Technology have won a prestigious HFSP grant to study how oxygen levels influence early embryo development using a unique technology.
Fr, 10.7.2026
CEITEC
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CEITEC Technology Will Help Reveal How Oxygen Controls Embryo Development
Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability
Article | Science and research

Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability

How can laboratories modernize legacy HPLC methods while remaining compliant? Learn how Opella leveraged UHPLC and evolving regulatory guidance to boost productivity.
Tu, 7.7.2026
Thermo Fisher Scientific
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Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability
Comparative Evaluation of Total Ergot Alkaloids Determination by ELISA and UHPLC-MS/MS in Wheat: Implications of Cross-Reactivity and Matrix Effects
Scientific article | Science and research

Comparative Evaluation of Total Ergot Alkaloids Determination by ELISA and UHPLC-MS/MS in Wheat: Implications of Cross-Reactivity and Matrix Effects

This study compares ELISA and UHPLC-MS/MS for ergot alkaloid analysis, highlighting the effects of cross-reactivity and sample matrix.
Mo, 6.7.2026
LabRulez
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Comparative Evaluation of Total Ergot Alkaloids Determination by ELISA and UHPLC-MS/MS in Wheat: Implications of Cross-Reactivity and Matrix Effects
Online Deglycosylation of Monomeric Intact Proteins Using the PNGase Rc Immobilized-Enzyme Reactor
Scientific article | Science and research

Online Deglycosylation of Monomeric Intact Proteins Using the PNGase Rc Immobilized-Enzyme Reactor

This study demonstrates fast online deglycosylation of intact glycoproteins using a PNGase Rc immobilized-enzyme reactor for bioanalysis.
Mo, 29.6.2026
LabRulez
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Online Deglycosylation of Monomeric Intact Proteins Using the PNGase Rc Immobilized-Enzyme Reactor
New technology streamlines the development of aptamers, synthetic alternatives to antibodies
Article | Science and research

New technology streamlines the development of aptamers, synthetic alternatives to antibodies

Scientists at IOCB Prague developed a breakthrough technology that accelerates aptamer discovery, opening new opportunities for diagnostics, therapeutics, and wearable biosensors.
Fr, 26.6.2026
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
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New technology streamlines the development of aptamers, synthetic alternatives to antibodies
Computer simulations shed light on how unusual tRNAs change the rules of reading the genetic code
Article | Science and research

Computer simulations shed light on how unusual tRNAs change the rules of reading the genetic code

UCT Prague researchers contributed to a study showing how subtle changes in tRNA can alter genetic code reading and reveal unusual bacterial tRNAs that can read stop codons.
Th, 25.6.2026
UCT Prague
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Computer simulations shed light on how unusual tRNAs change the rules of reading the genetic code
Accelerating Biomarker Discovery and Validation: From Discovery to Clinical Utility
Article | Science and research

Accelerating Biomarker Discovery and Validation: From Discovery to Clinical Utility

Thermo Fisher Scientific’s MSACL 2025 workshop showcased how automation, proteomics, and mass spectrometry accelerate biomarker discovery, verification, and clinical validation.
Tu, 23.6.2026
Thermo Fisher Scientific
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Accelerating Biomarker Discovery and Validation: From Discovery to Clinical Utility
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