Phenomenex Strata C18-U Solid Phase Extraction (SPE)

Moderate Hydrophobic Selectivity Solid Phase Extraction (SPE)

C18 sorbent with no end-capping, giving the phase moderate hydrophobic selectivity with slight polar selectivity due to the active silanol groups.

Phenomenex: Strata C18-U SPE

• Surface Area (m²/g): 500
• Separation Mode: Reversed Phase
• Pore Size: 70
• Particle Size: 55
• Recommended Use: Enhanced cleanup of hydrophobic compounds that contain hydroxy or amine functional groups

Starting Method

Strata Reversed Phase

• Condition: 1 mL Methanol
• Equilibrate: 1 mL DI Water
• Load: Pretreated sample
• Wash: 1 mL 5% Methanol in DI Water, dry under vacuum for 2-5 min
• Elute: 1 mL Methanol

Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.