Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation
Regenerating liver redirects ammonia metabolism to fuel de novo pyrimidine synthesis, enabling cell proliferation and tissue repair after hepatectomy through metabolic reprogramming.
Synthesis and Evaluation of Pyridine-Based Antibacterial Agents that Inhibit ATP Synthase in Acinetobacter baumannii
A new class of trisubstituted pyridines targets ATP synthase in Acinetobacter baumannii. Four lead compounds showed potent antibacterial effects and synergized with colistin against multidrug-resistant strains.
Mo, 3.11.2025
LabRulez
Scientific article | Science and research
Semisynthesis of Stable Isotope-Labeled Ergot Alkaloids for HPLC-MS/MS Analysis
A semisynthetic method enabled the preparation of stable isotope-labeled ergot alkaloids for precise HPLC-MS/MS quantification.
Mo, 3.11.2025
LabRulez
Scientific article | Science and research
Determination of Chemical Mixtures in Environmental, Food, and Human Samples Using High-Resolution Mass Spectrometry-Based Suspect Screening Approaches
Suspect screening using LC- and GC-HRMS identified 547 chemicals across environmental, food, and human samples. Pharmaceuticals, pesticides, and personal care products were the most frequent contaminants.
Mo, 3.11.2025
LabRulez
Article | Application
News from LabRulezLCMS Library - Week 44, 2025
This week we bring you application notes by Agilent Technologies, ALS Europe, Shimadzu and Waters Corporation and poster by Thermo Fisher Scientific!
Paired Pulsed Decarboxylative Hydroxylation Designed by Online Electrochemistry–Mass Spectrometry
A VESI-MS strategy allows real-time monitoring of redox processes, enabling rational pulse design for selective decarboxylative hydroxylation using only O₂, water, and carbon electrodes.