Metabolomic and Proteomic Analysis of ApoE4-Carrying H4 Neuroglioma Cells in Alzheimer’s Disease Using OrbiSIMS and LC-MS/MS
Article | Scientific article

Metabolomic and Proteomic Analysis of ApoE4-Carrying H4 Neuroglioma Cells in Alzheimer’s Disease Using OrbiSIMS and LC-MS/MS

In the article published in the ACS Analytical Chemistry, the researchers utilized OrbiSIMS to examine molecular alterations in Apolipoprotein E4-carried neuroglioma cells compared to wild-type H4 cells.
Tu, 8.10.2024
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Metabolomic and Proteomic Analysis of ApoE4-Carrying H4 Neuroglioma Cells in Alzheimer’s Disease Using OrbiSIMS and LC-MS/MS
NPLC method to characterize end groups of poly lactic acid co-glycolic acid copolymers
Article | Scientific article

NPLC method to characterize end groups of poly lactic acid co-glycolic acid copolymers

Masashi Serizawa recently published a manuscript describing a NPLC method to differentiate PLGA with different end groups (ester and acid terminated) and chemical compositions.
Th, 3.10.2024
Chemometrics and Advanced Separations Team (CAST)
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NPLC method to characterize end groups of poly lactic acid co-glycolic acid copolymers
Fast and efficient size exclusion chromatography of adeno associated viral vectors with 2.5 micrometer particle low adsorption columns
Article | Scientific article

Fast and efficient size exclusion chromatography of adeno associated viral vectors with 2.5 micrometer particle low adsorption columns

The researchers demonstrated the use of a newly developed 2.5 µm column with superior kinetic efficiency, reduced run times, and improved resolution for the analysis of Adeno Associated Viruses (AAVs).
Tu, 1.10.2024
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Fast and efficient size exclusion chromatography of adeno associated viral vectors with 2.5 micrometer particle low adsorption columns
Advancing Fundamental Understanding of Retention Interactions in Supercritical Fluid Chromatography Using Artificial Neural Networks: Polar Stationary Phases with –OH Moieties
Article | Scientific article

Advancing Fundamental Understanding of Retention Interactions in Supercritical Fluid Chromatography Using Artificial Neural Networks: Polar Stationary Phases with –OH Moieties

The researchers used artificial neural networks to advance a fundamental understanding of retention interactions in supercritical fluid chromatography.
Tu, 24.9.2024
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Advancing Fundamental Understanding of Retention Interactions in Supercritical Fluid Chromatography Using Artificial Neural Networks: Polar Stationary Phases with –OH Moieties
Finding evidence in plants for the use of chemical weapons
Article | Scientific article

Finding evidence in plants for the use of chemical weapons

Analytical Scientists at the University of Amsterdam’s together with colleagues from TNO have demonstrated that chemical warfare agents react with plant proteins to form stable protein adducts.
Th, 19.9.2024
University of Amsterdam
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Finding evidence in plants for the use of chemical weapons
Tips and tricks for LC–MS-based metabolomics and lipidomics analysis
Article | Scientific article

Tips and tricks for LC–MS-based metabolomics and lipidomics analysis

In the in Trends in Analytical Chemistry journal the researchers from the Institute of Physiology of the Czech Academy of Sciences, gave comprehensive overview of metabolomics and lipidomics tools.
Tu, 17.9.2024
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Tips and tricks for LC–MS-based metabolomics and lipidomics analysis
New technique measures psilocybin potency of mushrooms
Article | Scientific article

New technique measures psilocybin potency of mushrooms

Identifying dosages for psilocybin and psilocin key as medical uses grow.
Th, 12.9.2024
The University of Texas at Arlington
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New technique measures psilocybin potency of mushrooms
An FDA-Validated, Self-Cleaning Liquid Chromatography–Mass Spectrometry System for Determining Small-Molecule Drugs and Metabolites in Organoid/Organ-on-Chip Medium
Article | Scientific article

An FDA-Validated, Self-Cleaning Liquid Chromatography–Mass Spectrometry System for Determining Small-Molecule Drugs and Metabolites in Organoid/Organ-on-Chip Medium

In an article in ACS Analytical Chemistry the researchers introduced an LC-MS-based method for measuring small-molecule drugs and metabolites directly from liver organoids and organ-on-chip (OoC) systems.
Tu, 10.9.2024
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An FDA-Validated, Self-Cleaning Liquid Chromatography–Mass Spectrometry System for Determining Small-Molecule Drugs and Metabolites in Organoid/Organ-on-Chip Medium
Team aims to improve safety of fertilizers made from wastewater sludge
Article | Scientific article

Team aims to improve safety of fertilizers made from wastewater sludge

Johns Hopkins researchers create new list of possibly toxic contaminants commonly found in biosolids nationwide.
Fr, 6.9.2024
Johns Hopkins University
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Team aims to improve safety of fertilizers made from wastewater sludge
High-Throughput Chromatographic Separation of Oligonucleotides: A Proof of Concept Using Ultra-Short Columns
Article | Scientific article

High-Throughput Chromatographic Separation of Oligonucleotides: A Proof of Concept Using Ultra-Short Columns

In the in ACS Analytical Chemistry the researchers took a deep dive into understanding the retention mechanism of oligonucleotides, and evaluation of the linear solvent strength (LSS) retention model.
Tu, 3.9.2024
LabRulez
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High-Throughput Chromatographic Separation of Oligonucleotides: A Proof of Concept Using Ultra-Short Columns
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