LCMS
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Assessment of LC-QTOF-MS data independent acquisition for quantification and suspect screening of pesticides in agriculture impacted water samples
Scientific article | Science and research

Assessment of LC-QTOF-MS data independent acquisition for quantification and suspect screening of pesticides in agriculture impacted water samples

This study assesses the use of LC-QTOF-MS with data independent acquisition for quantifying target pesticides and screening suspects in agriculture-impacted water samples.
Mo, 12.5.2025
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Integrating NMR and multi-LC-MS-based untargeted metabolomics for comprehensive analysis of blood serum samples
Scientific article | Science and research

Integrating NMR and multi-LC-MS-based untargeted metabolomics for comprehensive analysis of blood serum samples

This study aims to create and validate a serum preparation method enabling combined untargeted NMR and multi-LC-MS analysis from one sample, enhancing efficiency and metabolome coverage.
Mo, 5.5.2025
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Dispersion properties of triply periodic minimal surface stationary phases for LC: The case of superficial adsorption
Scientific article | Science and research

Dispersion properties of triply periodic minimal surface stationary phases for LC: The case of superficial adsorption

The study assesses dispersion and plate height behavior in 3D-printed TPMS stationary phases, identifying optimal structures for LC based on flow and retention performance.
Mo, 28.4.2025
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Ion exchange chromatography of biotherapeutics: Fundamental principles and advanced approaches
Scientific article | Science and research

Ion exchange chromatography of biotherapeutics: Fundamental principles and advanced approaches

This review outlines IEX fundamentals and explores advanced strategies—like pH gradients, ultra-short columns, and coupling with MS—for characterizing complex biotherapeutics.
Mo, 21.4.2025
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Mass Spectrometry Imaging with Trapped Ion Mobility Spectrometry Enables Spatially Resolved Chondroitin, Dermatan, and Hyaluronan Glycosaminoglycan Oligosaccharide Analysis In Situ
Scientific article | Science and research

Mass Spectrometry Imaging with Trapped Ion Mobility Spectrometry Enables Spatially Resolved Chondroitin, Dermatan, and Hyaluronan Glycosaminoglycan Oligosaccharide Analysis In Situ

This study introduces an MSI-TIMS method to identify and spatially resolve GAG oligosaccharides and their sulfation states directly from retinal tissue sections.
Mo, 14.4.2025
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Comparison of carrier gases for the separation and quantification of mineral oil hydrocarbon (MOH) fractions using online coupled high performance liquid chromatography-gas chromatography-flame ionisation detection
Scientific article | Science and research

Comparison of carrier gases for the separation and quantification of mineral oil hydrocarbon (MOH) fractions using online coupled high performance liquid chromatography-gas chromatography-flame ionisation detection

This study evaluates hydrogen, helium, and nitrogen as carrier gases in HPLC-GC-FID for MOH analysis in food, showing nitrogen as a suitable and effective alternative despite some peak broadening.
Mo, 14.4.2025
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Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics
Scientific article | Science and research

Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics

This study evaluates matrix effects in untargeted HILIC-MS plasma metabolomics using post-column infusion, identifying optimal conditions and improving method reliability for metabolite analysis.
Mo, 7.4.2025
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Hydrophilic interaction liquid chromatography: An efficient tool for assessing thorium interaction with phosphorylated biomimetic peptides
Scientific article | Science and research

Hydrophilic interaction liquid chromatography: An efficient tool for assessing thorium interaction with phosphorylated biomimetic peptides

This study uses HILIC-MS to explore how thorium interacts with phosphorylated biomimetic peptides, revealing its affinity and selectivity versus uranium for toxicity modeling.
Mo, 31.3.2025
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Modeling indirectly detected analyte peaks in ion-pair reversed-phase chromatography
Scientific article | Science and research

Modeling indirectly detected analyte peaks in ion-pair reversed-phase chromatography

This study models indirect detection using co- and counter-ion probes in chromatography. New isotherm models accurately predicted elution and sensitivity, with errors mostly under 4.72%.
Mo, 24.3.2025
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Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS
Scientific article | Science and research

Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS

This study presents an HPLC-ICP-MS method for precise quantification of Gd complexes in Gadoquatrane, enabling detection of trace by-products to optimize synthesis and drug control strategies.
Mo, 17.3.2025
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LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike