Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry
Scientific article | Science and research

Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry

This study introduces an HDX-MS titration workflow for quantifying protein–ligand affinities at global, peptide, and residue resolution.
Mo, 20.7.2026
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Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry
Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach
Scientific article | Science and research

Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach

This study uses temperature-controlled IM-MS to monitor protein unfolding and oligomer formation in real time, revealing early aggregation pathways.
Mo, 13.7.2026
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Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach
Comparative Evaluation of Total Ergot Alkaloids Determination by ELISA and UHPLC-MS/MS in Wheat: Implications of Cross-Reactivity and Matrix Effects
Scientific article | Science and research

Comparative Evaluation of Total Ergot Alkaloids Determination by ELISA and UHPLC-MS/MS in Wheat: Implications of Cross-Reactivity and Matrix Effects

This study compares ELISA and UHPLC-MS/MS for ergot alkaloid analysis, highlighting the effects of cross-reactivity and sample matrix.
Mo, 6.7.2026
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Comparative Evaluation of Total Ergot Alkaloids Determination by ELISA and UHPLC-MS/MS in Wheat: Implications of Cross-Reactivity and Matrix Effects
Online Deglycosylation of Monomeric Intact Proteins Using the PNGase Rc Immobilized-Enzyme Reactor
Scientific article | Science and research

Online Deglycosylation of Monomeric Intact Proteins Using the PNGase Rc Immobilized-Enzyme Reactor

This study demonstrates fast online deglycosylation of intact glycoproteins using a PNGase Rc immobilized-enzyme reactor for bioanalysis.
Mo, 29.6.2026
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Online Deglycosylation of Monomeric Intact Proteins Using the PNGase Rc Immobilized-Enzyme Reactor
Untargeted Metabolomics Identifies N-Lactoyl-Amino Acids as Dose-Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes
Scientific article | Science and research

Untargeted Metabolomics Identifies N-Lactoyl-Amino Acids as Dose-Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

This study identifies N-lactoyl-amino acids as plasma biomarkers that accurately reflect metformin exposure and treatment adherence in T2D.
Mo, 22.6.2026
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Untargeted Metabolomics Identifies N-Lactoyl-Amino Acids as Dose-Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes
Benchmarking Lysosome Enrichment Methods: A Guide for Research and Clinical Translation
Scientific article | Science and research

Benchmarking Lysosome Enrichment Methods: A Guide for Research and Clinical Translation

This study benchmarks four lysosome isolation techniques, highlighting trade-offs in enrichment, purity, scalability, and reproducibility.
Mo, 15.6.2026
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Benchmarking Lysosome Enrichment Methods: A Guide for Research and Clinical Translation
Complexation of Plutonium and Other Actinides in Different Oxidation States with Gluconate at Low pH Values─A CE-ICP-MS Study
Scientific article | Science and research

Complexation of Plutonium and Other Actinides in Different Oxidation States with Gluconate at Low pH Values─A CE-ICP-MS Study

This study uses CE-ICP-MS to investigate gluconate complexes of plutonium and other actinides, revealing oxidation-state-dependent binding behavior.
Mo, 8.6.2026
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Complexation of Plutonium and Other Actinides in Different Oxidation States with Gluconate at Low pH Values─A CE-ICP-MS Study
Determination of Flibanserin in Female Sexual Desire Enhancer Products by LC–MS/MS and Its Confirmation by LCMS-IT-TOF
Scientific article | Science and research

Determination of Flibanserin in Female Sexual Desire Enhancer Products by LC–MS/MS and Its Confirmation by LCMS-IT-TOF

This study develops a rapid LC-MS/MS method for flibanserin analysis and finds little or no active ingredient in commercial female enhancer products.
Mo, 8.6.2026
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Determination of Flibanserin in Female Sexual Desire Enhancer Products by LC–MS/MS and Its Confirmation by LCMS-IT-TOF
Characterisation of small RNA-based therapeutics and their process impurities by fast and sensitive liquid chromatography high resolution mass spectrometry
Scientific article | Science and research

Characterisation of small RNA-based therapeutics and their process impurities by fast and sensitive liquid chromatography high resolution mass spectrometry

This study presents a sensitive LC-HRMS method for sequence verification and impurity profiling of RNA-based therapeutics.
Mo, 1.6.2026
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Characterisation of small RNA-based therapeutics and their process impurities by fast and sensitive liquid chromatography high resolution mass spectrometry
From the Road to the Field: Decoding Chemical Transformation in Aging Tire and Artificial Turf Crumb Rubber
Scientific article | Science and research

From the Road to the Field: Decoding Chemical Transformation in Aging Tire and Artificial Turf Crumb Rubber

This study investigates chemical aging of tire and turf crumb rubber, identifying hundreds of transformation products and potential aging markers.
Mo, 25.5.2026
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From the Road to the Field: Decoding Chemical Transformation in Aging Tire and Artificial Turf Crumb Rubber
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