UCT Prague researchers introduce “Lab-on-a-Scalpel,” a 3D-printed surgical tool with an electrochemical sensor, offering a glimpse into real-time diagnostics during surgery.

This study introduces acrylamide monolith HILIC-MS for intact mAb glycoprofiling, offering high selectivity, baseline separation, and detection of low-abundance glycoforms missed by RPLC-MS.

The ATEBIO workshop in Hradec Králové introduced students to modern automated sample preparation using nanofibers and programmable systems in lab practice.

Scientists at IOCB Prague created MSⁿLib, a vast mass spectrometry library with millions of records, enabling rapid unknown compound identification and boosting drug discovery and biomedical AI.

Ion-pairing HILIC improves impurity profiling of therapeutic oligonucleotides. It resolves deaminated impurities from full-length products, beyond current LC-MS limits.

Discover why fragmentation is vital in mass spectrometry for peptide sequencing, protein characterization, and advanced proteomics applications.

Cows fed multispecies swards produced milk with more polyunsaturated and bioactive fatty acids than ryegrass systems, suggesting benefits for milk quality and consumer health.

A novel AF4-MALS and Py-GC-MS workflow enables size-resolved polymer analysis of nanoplastics in wastewater. It improves detection, quantification, and offers insights into polymer composition.

Researchers at IOCB Prague developed a simple and universal late-stage iodine-125 labeling method for peptides and proteins, enabling faster, cheaper, and high-quality production for drug discovery.

Using UPLC-HRMS and SIMCA, 159 NPS standards were analyzed to build classification models. The approach showed strong validation and accurate identification of seized samples, aiding forensic drug analysis.