Chemists at IOCB Prague developed a fast, robust SNAr-based method to synthesize drug-like atropisomers, unlocking access to hindered C–N bonds with practical and mild conditions.

Which SEC column best separates AAV size variants? A new study compares six wide-pore columns and reveals surprising insights for gene therapy product characterization.

A rapid, green LC-QqQ-MS/MS method quantifies N-MOX and DNPP in moxifloxacin tablets and eye drops. Validated per ICH, it ensures safety by detecting trace NDSRIs with minimal environmental impact.

Discover how MSCA and ERA fellowships empowered two RECETOX researchers to grow as independent scientists, tackle global health challenges, and inspire future scientific careers.

Novel LC-MS/MS and UPLC methods quantify NDSRI in mefenamic acid tablets and suspensions with high sensitivity, accuracy, and eco-friendly evaluation via multiple green metrics.

Scientists developed a catalyst that uses sunlight and water to hydrogenate a wide range of organics with high yield and selectivity—no gas hydrogen or harsh conditions needed.

MALDI-MSI on SELECT SERIES MALDI-MRT was optimized for fingerprint imaging. The method improves resolution and enables detection of drugs like antipsychotics in latent prints.

A team led by Prof. Jan Konvalinka has developed a compound that destroys the yeast Cryptococcus neoformans – a fungus which is life-threatening for people with weakened immune systems – in laboratory settings.

This study aims to develop and validate a rapid IC-ICP-MS method for identifying and quantifying polyphosphonates and their transformation products under environmental conditions.

The study examines treated wastewater from Arctic cruise ships to identify pharmaceuticals and other contaminants, highlighting potential risks to sensitive polar marine environments.