<p><strong>In the week from March 29, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>700 LC and GC webinars</strong>.</p>
<h5><strong>1. Waters Corporation: Increasing Efficiency in a Remote Environment</strong></h5>
<p>In this webinar we’ll discuss how laboratory automation can help address some of new challenges due to pandemic situation and enhance COVID-19 research.</p>
<h5><strong>2. C&amp;EN/Bruker Daltonics: MALDI Tandem Mass Spectrometry – the Most Versatile Analytical Tool for Analysis of Polymeric Materials</strong></h5>
<p>Advantages of MALDI/MS/MS will be demonstrated with the precise structural analysis of a wide variety of synthetic materials, including large and crosslinked polymers, additives and synthetic polymer surfaces.</p>
<h5><strong>3. VWR: Back To Basics: Fundamental Concepts of HPLC &amp; UHPLC</strong></h5>
<p>The basis of the separation process and retention mechanisms will be covered, as well as how the important parameters of resolution, peak shape and efficiency are measured.</p>
<h5><strong>4. Agilent Technologies: Characterization of MassTech AP MALDI Source with Agilent 6545 QTOF and 6560 IM-QTOF for MS Imaging</strong></h5>
<p>The AP MALDI source developed by MassTech Inc was hyphenated to Agilent 6545, a high-resolution mass spectrometer. AP MALDI MS imaging was demonstrated using tissue-simulating peptide spots.</p>
<h5><strong>5. Phenomenex: Understanding Ion-Exchange Selectivity In Biomolecules Analysis</strong></h5>
<p>In this webinar we will cover: Ion Exchange Chromatography, PTMs &amp; Charge Heterogeneity, bioZen WCX, Effects of pH &amp; Common Buffers, Salts VS pH Gradient, Method Optimization, etc...</p>
<h5><strong>6. SelectScience/Agilent Technologies: Comprehensive pesticide testing required to ensure safe cannabis and cannabinoid products</strong></h5>
<p>In this SelectScience webinar, learn analytical methodologies for comprehensive targeted and semi-targeted pesticide analysis to better ensure the safety of cannabis products, where legalized.</p>
<h5><strong>7. Waters Corporation: A Focus on PCR Diagnostic Probes: Oligonucleotide LC Analysis and Purification</strong></h5>
<p>We’ll discuss strategies for lab scale and semi-preparative purification of diagnostic probes through illustrated examples. In addition, we’ll review PREMIER solutions.</p>
<h5><strong>8. Technology Networks/SCIEX: Digital Freezing of Metabolomics Samples</strong></h5>
<p>This webinar showcases the use of SWATH® Acquisition on the benchtop X500R QTOF System for digital freezing of metabolomics samples.</p>
<h5><strong>9. Agilent Technologies: WHY Did That Happen?</strong></h5>
<p>In this webinar we will discuss some common problems, how to identify their source, and how to fix them.</p>
<h5><strong>10. Agilent Technologies: Analysis of Water-Soluble B Vitamins by the Ultivo LC-MS TQ</strong></h5>
<p>In this webinar we will present analysis of Water-Soluble B Vitamins by the Agilent Ultivo LC-MS TQ (triple quadrupole liquid chromatography/mass spectrometry system).</p>
<h5><strong>11. Agilent Technologies: Agilent RapidFire 400: A Complete Approach To High-Throughput Mass Spectrometry</strong></h5>
<p>Explore some of the applications being accelerated using RapidFire and learn how it can enhance your laboratory’s capabilities.</p>


LC and LCMS webinars - Week 13

<p><strong>In the week from April 5, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>700 LC and GC webinars</strong>.</p>
<h5><strong>1. Agilent Technologies: Advanced Algorithms for the Discovery of Related Components and Application to PFAS and Fentanyl Research</strong></h5>
<p>The MassHunter acquisition concept of a Preferred MSMS list will be presented together with concept of Mass Defect, MSMS pseudo Constant Neutral Loss, and MSMS Reporter Ions.</p>
<h5><strong>2. Technology Networks/SCIEX: Accelerating AAV-Based Gene Therapy Development with MS</strong></h5>
<p>Using MS data to improve characterization of AAV from different sources will help scientists to make informed decisions in the development of cost-effective, safe and potent gene therapeutics.</p>
<h5><strong>3. Technology Networks/Bruker: Flow Injection Analysis-Magnetic Resonance Mass Spectrometry for High-Throughput Metabolomics</strong></h5>
<p>This webinar will introduce the FIA-MRMS workflow and present two case studies where it is used.</p>
<h5><strong>4. The Analytical Scientist/PIC Solution: Advances in Eco-Sustainable CO2 Technologies</strong></h5>
<p>The Forum provides a unique opportunity to discuss advances in next-generation of eco-sustainable CO2 Separation (SFC) and Extraction (SFE) technologies.</p>
<h5><strong>5. Agilent Technologies: Mass Spectrometry for the Masses, Open Access LC and LC/MS Using Agilent WalkUp</strong></h5>
<p>We will provide an introduction to WalkUp briefly discussing the user experience from the administrator (setting up groups, users, methods, data analysis confirmation) and users’ (running samples) perspectives.</p>
<h5><strong>6. Waters Corporation: Nitrosamines Analysis (Step 2): Confirmatory testing</strong></h5>
<p>In this webinar, we will going through the latest regulatory requirements for testing nitrosamines in solvents, drug substance and drug products.</p>
<h5><strong>7. Shimadzu Scientific Instruments: Subsurface Microbiology: Metabolism by HPLC</strong></h5>
<p>In this work, we discovered a novel strict anaerobic thermophilic bacterium from a monitoring borehole at a depth of 691 meters below land surface.</p>
<h5><strong>8. Agilent Technologies: VWorks version 14.0: Enhanced Features of Compliance</strong></h5>
<p>Join us and learn about how the new VWorks comes in two different editions to suit your laboratory’s specific regulatory needs.</p>


LC and LCMS webinars - Week 14

<p><strong>In the week from April 12, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>700 LC and GC webinars</strong>.</p>
<h5><strong>1. PerkinElmer: Food Safety: Determination of Mycotoxins in food by LC-MS/MS</strong></h5>
<p>This webinar will present insights into risk assessment with a focus on the LC-MS/MS methods, along with solutions for performing selective, sensitive and compliant analysis. </p>
<h5><strong>2. Thermo Fisher Scientific: Charged Aerosol Detection Symposium - Session 1</strong></h5>
<p>Join our interactive and live charged aerosol detection symposium with tips, tricks, pointers and expert advice from our guest speakers! </p>
<h5><strong>3. Phenomenex: Strategies, Tips and Tricks for Simplified Chiral Method Development</strong></h5>
<p>In this presentation, we will explore the factors that contributes to successful chiral separation.</p>
<h5><strong>4. Agilent Technologies: A Comprehensive Approach to Targeted and Untargeted Screening Methodology for Emerging Synthetic Fentanyl Analogues using High Resolution Accurate Mass Spectrometry</strong></h5>
<p>Herein, a targeted and untargeted screening workflow by LC/MS/MS using Agilent’s 6546 QTOF will be presented for approximately 150 fentanyl analogues.</p>
<h5><strong>5. Thermo Fisher Scientific: Charged Aerosol Detection Symposium - Session 2</strong></h5>
<p>Learn how CAD can be applied in your work with tips, tricks, pointers, and expert advice from our guest speakers.</p>
<h5><strong>6. Waters Corporation: Benefits of IMS to MetID and Structural Elucidation</strong></h5>
<p>Our two guest speakers Dr. Ralf Laux and Dr. Ian Wilson bring decades of experience in Drug Metabolism and Pharmacokinetics.</p>
<h5><strong>7. LCTech: FREESTYLE XANA - The Specialist for your Water Samples</strong></h5>
<p>Learn more about FREESTYLE XANA robotic system for automatic SPE sample preparation for analysis of large volumes of water samples.</p>
<h5><strong>8. Waters Corporation: Solving Large Molecule Questions with Accessible LC/MS in Academia</strong></h5>
<p>Join Christian Winter, UNI of Frankfurt, and Dr John Walsby-Tickle, UNI of Oxford, online to learn how an easy-to-use routine LC/MS brings academics in life sciences closer to the point of decision.</p>
<h5><strong>9. Thermo Fisher Scientific: Charged Aerosol Detection Symposium - Session 3</strong></h5>
<p>Learn more from our speakers in these industries sharing tips and tricks, with pointers, and expert advice. </p>
<h5><strong>10. Bruker Daltonics: Bead Assisted Mass Spectrometry assay platform for targeted proteomics</strong></h5>
<p>The webinar will focus on the detailed description of the workflow and case studies of BAMS™ assays developed for targets relevant to neurology and virology.</p>
<h5><strong>11. SelectScience/Merck: BioSPME: A new tool for drug-protein binding determination</strong></h5>
<p>In this webinar, Dr. Olga Shimelis will present the use of new product – Supel™ BioSPME C18 96-Pin Devices – for in vitro measurement of protein binding properties of pharmaceutical compounds in plasma. </p>
<h5><strong>12. Thermo Fisher Scientific: The Delights of Diversity: A Multitude of Separation Techniques Combined with Mass Spectrometry for Characterization in Biopharmaceutical Development</strong></h5>
<p>Here the impact of hyphenating a broad range of separation techniques to high resolution accurate mass (HRAM) mass spectrometry (MS) will be discussed through case studies.</p>
<h5><strong>13. Agilent Technologies: WHO Do I Turn To? Chromatography Resources</strong></h5>
<p>Looking for answers to your chromatography questions? Who do you turn to? This webinar will look at available resources to help meet your chromatography needs.</p>
<h5><strong>14. SelectScience/Waters Corporation/Andrew Alliance: Virtual Event: Leveraging automation technologies to work smarter</strong></h5>
<p>This virtual event brings you three webinars from experts in the field of automation who will discuss how you can work smarter.</p>


LC and LCMS webinars - Week 15

<p><strong>In the week from April 19, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>800 LC and GC webinars</strong>.</p>
<h5><strong>1. Dr. Maisch High Performance LC GmbH: Chiral HPLC: From Basics to the Latest and Unique Novelties</strong></h5>
<p>We invite you to join our free webinar to understand the principles of chiral HPLC, different types of stationary phases and their characteristics and separation modes.</p>
<h5><strong>2. Separation Science/Thermo Fisher Scientific: The Challenges of Pesticide Analysis - LC or GC Triple Quadrupole?</strong></h5>
<p>This webinar takes a look at the pros and cons of LC-QqQ and GC-QqQ for the analysis of pesticides in food and agricultural matrices. Industry and technology experts will provide their insights.</p>
<h5><strong>3. C&amp;EN/Wyatt Technology: Quality attributes and extended characterization of lentiviral and gammaretroviral vectors using light scattering</strong></h5>
<p>We will demonstrate batch dynamic light scattering (DLS) for rapid, low-resolution measurements and MALS in combination with field-flow fractionation (FFF) for extended characterization of viral vectors.</p>
<h5><strong>4. Thermo Fisher Scientific: BioPharma Finder software for characterization of protein and oligonucleotide based biotherapeutics</strong></h5>
<p>BioPharma Finder software is a workflow driven solution for complete characterization of biotherapeutics.</p>
<h5><strong>5. Agilent Technologies: Method Development &amp; Optimization Workshop</strong></h5>
<p>In this online workshop, Agilent presents the common challenges faced these days and focuses on Method Development Solutions with maximum efficiency to optimize your workflows.</p>
<h5><strong>6. Phenomenex: LC Method Development and Problem Prevention for Pharmaceutical Methods</strong></h5>
<p>This webinar will cover topics like LC Column Selection and Method Development and Overview of USP Allowable Adjustments and Avoid LC Problems through Proper Column Care and Troubleshooting.</p>
<h5><strong>7. Waters Corporation: Meet the Experts - Part 1 - Alternative Procurement Strategies</strong></h5>
<p>Richard Styles details the alternative buying options available to you in today&#39;s market. </p>
<h5><strong>8. Wiley Analytical Science/Merck: Lipidomics from Structure to Function</strong></h5>
<p>Part I: Lipidomics from Structure to Function</p>
<h5><strong>9. Wiley Analytical Science/Merck: Quantitative Bottom-Up Shotgun Lipidomics Using High-Resolution Orbitrap FTMS</strong></h5>
<p>Part II: Quantitative Bottom-Up Shotgun Lipidomics Using High-Resolution Orbitrap FTMS</p>
<h5><strong>10. Thermo Fisher Scientific: GlycanExplorer – A software solution for high throughput bio-therapeutic glycan characterization</strong></h5>
<p>In this presentation, we will discuss how the software detects the peaks from your raw data, identify the probable glycans with the help of different search workflows, and present the results.</p>
<h5><strong>11. Petro Industry News/Waters Corporation: High Resolution MS and Statistical Analysis Approaches to Lubricant Formulation Research and Development</strong></h5>
<p>We will outline a simple and efficient workflow that uses HRMS and statistical analysis of the acquired data to understand the differences between several automotive lubricant oils at a molecular level.</p>
<h5><strong>12. Waters Corporation: MaxPeak HPS Innovation to reduce analyte/surface interactions</strong></h5>
<p>This 1st session will introduce you to MaxPeak High Performance Surface (HPS) technology, the integral part of our ACQUITY PREMIER Solution to reduce analyte/surface interactions.</p>
<h5><strong>13. Wiley Analytical Science/YMC Europe:Characterisation and Quantification of Biomolecules</strong></h5>
<p>The first part of the talk will provide a brief introduction to bioanalytics in general, as well as to the quantification and characterization of intact proteins.</p>
<h5><strong>14. Wiley Analytical Science/YMC Europe: Analysing Antibodies by Different LC Separation Modes</strong></h5>
<p>The second part is dedicated to peptide analysis and covers classical and multidimensional chromatography as well as automated sample preparation using enzyme reactors.</p>
<h5><strong>15. Thermo Fisher Scientific: Increasing proteoform level insight with quantitative Top-Down proteomics using Proteome Discoverer 2.5 software</strong></h5>
<p>This presentation will provide and overview of Top-Down proteomics from sample prep to generating results. Topics will be presented in practical terms with relevant background information. </p>
<h5><strong>16. Agilent Technologies: Cannabis Safety - Trace Analysis of Pesticides &amp; Mycotoxins via LC/QQQ in Cannabis Flower and Concentrates</strong></h5>
<p>This presentation will detail an LC/MS/MS analytical workflow developed by Agilent for the accurate measurement of combined pesticide and mycotoxin action lists according to the requirements of U.S.</p>


LC and LCMS webinars - Week 16

<p><strong>MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release.</strong> </p>
<p>I will attempt to introduce the user to the use of the <strong>NIST Version 2.4 search software</strong> employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the <strong>identification of unknowns</strong>.</p>
<p>NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. </p>
<p>See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a></p>
<p>This involves a very comprehensive process for <strong>selecting</strong> pertinent compounds for purchase and subsequent <strong>analyses</strong>. The problem with variability of the spectra is reduced by analyzing the samples on a <strong>variety of instruments</strong> at a <strong>variety of energy levels</strong> (20 steps). In addition, many different <strong>precursor ions</strong> and <strong>fragment ions</strong> are characterized (MSⁿ). This has already led to a very large high quality library of <strong>accurate mass MS/MS spectra in the 2020 release version</strong> (31K compounds/1.3 M spectra) and the effort is ongoing.</p>
<h3><strong>The Part VI will cover:</strong></h3>
<p>Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.</p>
<ul>
<li>Introduction of Presenter, James Little</li>
<li>Table of Contents</li>
<li>Series Topics</li>
<li>Help Files for NIST Search </li>
<li>NIST Software in General is “Windows Compliant” </li>
<li>Session Topics </li>
<li>Adding a Structure to a Spectrum</li>
<li>Sending Spectrum with Structure to MS Interpereter </li>
<li>Processing Data in MS Interpreter </li>
<li>Suggested Default Settings</li>
<li>Displaying the Propose Substructures Correlated to Ions </li>
<li>Stepping through More Than One Proposed Structure </li>
<li>Lassoing Structures Manually </li>
<li>Processing Any Entry in NIST Search with structure/spectrum</li>
<li>Direct Structure Paste in MS Interpreter </li>
<li>Processing MS/MS Spectra Containing Isotopic Clusters</li>
<li>Live YouTube Demonstration</li>
<li>References with Internet Links</li>
<li>Acknowledgements</li>
</ul>
<h3><strong>Future parts will focus on:</strong></h3>
<ul>
<li>Part VII:  <strong>Using and Creating Other MSMS Libraries</strong></li>
<li>Part VIII: <strong>Identification of Unknowns with “Spectraless” Libraries</strong></li>
</ul>
<h3><strong>The past sections have focused on:</strong></h3>
<ul>
<li><p><a href="https://lcms.labrulez.com/article/1068"><strong>Part I: Overview of Software and User-Customized Configurations</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1088"><strong>Part II: NIST Search Software and Libraries</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1110"><strong>Part III: More Detailed Discussion of MSMS Hybrid Search</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1130"><strong>Part IV: Importing MSMS Spectra</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1162"><strong>Part V: NIST Structure Searches</strong></a></p>
</li>
</ul>


LC/MS Unknown Identifications Using MSMS Libraries Part VI: MS Interpreter Correlation of Substructure to MSMS Ions

<p><strong>In the week from April 26, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>900 LC and GC webinars</strong>.</p>
<h5><strong>1. Agilent Technologies: MassHunter WalkUp: Making the Complex Simple, Part 1</strong></h5>
<p>This webinar explores what MassHunter WalkUp can do for your lab, highlights experience from administrator and users’ perspectives for various workflows, and demonstrates ease-of-use.</p>
<h5><strong>2. Thermo Fisher Scientific: Advancing carbohydrate analysis - Glycans</strong></h5>
<p>This webinar will talks about filling the gaps in glycan analysis with advanced ion chromatography column technology.</p>
<h5><strong>3. Waters Corporation: Is your system truly inert? - A PREMIER experience</strong></h5>
<p>Details on the development and application of PREMIER Standards to support the characterization of metal interactions to ensure performance and guide troubleshooting efforts will be discussed.</p>
<h5><strong>4. C&amp;EN/Advanced Materials Technology: Reversed phase liquid chromatography: fundamentals and strategies for faster method development</strong></h5>
<p>In this webinar we address the fundamental concepts that are key to developing optimized methods via Reversed Phase Liquid Chromatography (RPLC) (the most adopted and common mode of separation science).</p>
<h5><strong>5. Thermo Fisher Scientific: In-depth protein characterization with BioPharma Finder software – intact mass analysis, peptide mapping and new host cell protein workflow</strong></h5>
<p>Learn how to use in-depth protein characterization tools and how to analyze Host cell proteins in your biotherapeutic protein sample. </p>
<h5><strong>6. Phenomenex: Proper Method Scaling to Achieve Your UHPLC and HPLC Goals</strong></h5>
<p>This presentation aims to provide a framework within which to navigate the HPLC/UHPLC method scaling parameters to accomplish the goals of an analysis.</p>
<h5><strong>7. Agilent Technologies: Sensitive Techniques for Targeted PFAS Analysis in Water</strong></h5>
<p>W tomto webináři prozkoumáme použití nejnovější technologie QQQ 6495C a její schopnost tlačit citlivost na nižší hodnoty u složitějších PFAS, jako je GenX a zaměříme sea citlivost a vysokou propustnost vzorků.</p>
<h5><strong>8. Agilent Technologies: Using OpenLab to Enhance the Empower Experience</strong></h5>
<p>We will highlight how to manage Empower data in Technology Neutral formats such as AniML and Allotrope enabling long term record retention, data exchange, and cross platform reporting of multivendor data.</p>
<h5><strong>9. LECO: LECO MOSH/MOAH Workshop - Fundamentals On Comprehensive MOSH/MOAH Analysis – Day 1</strong></h5>
<p>Day one features Fundamentals on LC-GC Coupling and Principles and Instrumentation of GC×GC and ToF-MS.</p>
<h5><strong>10. Agilent Technologies: Virtual Ion Mobility Spectrometry (IMS) Mini-Symposium</strong></h5>
<p>The event consists of six short scientific IMS (Ion Mobility Spectrometry) presentations delivered by guest international speakers and Agilent R&amp;D scientists.</p>
<h5><strong>11. Wiley Analytical Science/Bruker: Highly Multiplexed Targeted Proteomics Acquisition on a TIMS-QTOF</strong></h5>
<p>The method&#39;s applicability is demonstrated by measuring Kras, Nras, and Hras in biological samples and the most common cancer-associated Kras mutations.</p>
<h5><strong>12. Waters Corporation: Benefits of the Cyclic IMS for HDX/MS Experiments</strong></h5>
<p>Hear from Mark Skehel on the use of Cyclic IMS to investigate the conformations of bovine mitochondrial complex I. </p>
<h5><strong>13. Wiley Analytical Science/Bruker: Leveraging prm-PASEF on the timsTOF Pro to Interrogate the Functional Proteome</strong></h5>
<p>Here we describe PASEF-PRM-LIVE, a framework implementing on-the-fly adjustment of the detection window to maximize target coverage. </p>
<h5><strong>14. Thermo Fisher Scientific: Automated online µSPE cartridge clean-up of QuEChERS extracts before LC-MS/MS and GC-MS/MS analysis of pesticides in foods.</strong></h5>
<p>We will highlight an automated online miniaturized cartridge clean-up approach providing more effective clean-up of QuEChERS extracts to overcome the analytical challenges in pesticide residue analysis.</p>
<h5><strong>15. Technology Networks/Bruker: MALDI Imaging – A Powerful Tool in Pathology</strong></h5>
<p>In this webinar, Kristina Schwamborn, will discuss how MALDI-IMS can overcome the limitations of other approaches in the discovery and identification of new classifying marker molecules and profiles.</p>
<h5><strong>16. Thermo Fisher Scientific: Getting the most out of Thermo Scientific&#39;s latest acquisition technologies FAIMS and SureQuant with Biognosys&#39; software solutions Spectronaut and SpectroDive</strong></h5>
<p>Two speakers from Biognosys, Next gen. proteomics solutions - will talk about the analysis of FAIMS-DIA data using Spectronaut software, and SureQuant targeted quantitation workflow using SpectroDive software.</p>
<h5><strong>17. Agilent Technologies: Resolve More Isoforms with the New Agilent 1290 Infinity II Bio LC System</strong></h5>
<p>Join Agilent Technologies LC Applications Scientist, for an in depth look Agilent Technologies’ new 1290 Infinity II Bio LC systems and decide the optimal pumping system for your application needs.</p>
<h5><strong>18. Thermo Fisher Scientific: Advancing carbohydrate analysis - Eluent generation</strong></h5>
<p>This webinar will talks about simplify the complexity of carbohydrate analysis with eluent generation.</p>
<h5><strong>19. Waters Corporation: LC-MS/MS multi-residue method: Routine analysis and workflow efficiency</strong></h5>
<p>The first episode of Pesticide Thursdays is dedicated to the Multiresidue Method for Quantification of Pesticides in Food by UPLC-MS/MS – SANTE guidelines, MQLs, and tools to modernize workflow efficiency.</p>
<h5><strong>20. LECO: LECO MOSH/MOAH Workshop - Fundamentals On Comprehensive MOSH/MOAH Analysis – Day 2</strong></h5>
<p>Day two features LC-GC×GC–ToF-MS/FID: A Powerful Platform for MOSH&amp;MOAH Determination.</p>
<h5><strong>21. VWR: Mini-symposium: Method development strategies and devising solutions for nitrosamine analysis</strong></h5>
<p>This webinar will cover: A Systematic UHPLC/HPLC Method Development Strategy with Complementary Stationary Phases to Maximise Selectivity and Resolution; Analysis of nitrosamines in APIs.</p>
<h5><strong>22. Waters Corporation: Comprehending COVID-19: The Application of a Mixed-Mode Stationary Phase for the Analysis of Small Molecule Drugs Evaluated for the Treatment of SARS-CoV-2 Infections</strong></h5>
<p>Join us for our upcoming COVID Spotlight webinar to learn about using Mixed-Mode Chromatography for small molecule drug analysis.</p>
<h5><strong>23. Evosep Biosystems: Robust and comprehensive Protein-Protein Interaction analysis with the Evosep One</strong></h5>
<p>In this webinar we will present: In-Cell Protein Footprinting Coupled with Mass Spectrometry for Structural Biology Across the Proteome and An atlas of protein-protein interactions across mouse tissues.</p>
<h5><strong>24. Agilent Technologies: Sample Preparation Options for the Clinical Research Laboratory</strong></h5>
<p>This seminar will discuss and compare sample preparation strategies for clinical research laboratories ranging from simple dilute and shoot to solid-phase extraction (SPE).</p>
<h5><strong>25. Thermo Fisher Scientific: In-depth oligonucleotide characterization with BioPharma Finder software – intact mass analysis, oligonucleotide analysis and mRNA mapping</strong></h5>
<p>Learn how to use in-depth oligonucleotide characterization tools including automatic sequencing of MS2 data to confirm the sequence of the biotherapeutic and how to perform mRNA mapping using HR LC MS/MS.</p>
<h5><strong>26. PerkinElmer: Improving Your Canna-business: Cannabinoid Monitoring in Dried Flower by the New PerkinElmer LC300 System</strong></h5>
<p>Join PerkinElmer’s Michael Costanzo, for a look into the science of potency testing via liquid chromatography, a method to test for 16 of the most common cannabinoids, and a brief look at the new LC 300.</p>
<h5><strong>27. Agilent Technologies: MassHunter WalkUp: Making the Complex Simple, Part 2</strong></h5>
<p>This webinar explores what MassHunter WalkUp can do for your lab, highlights experience from administrator and users’ perspectives for various workflows, and demonstrates ease-of-use.</p>


LC and LCMS webinars - Week 17

<p><strong>In the week from May 3, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>900 LC and GC webinars</strong>.</p>
<h5><strong>1. Agilent Technologies: Extend the possibilities with Agilent’s OpenLab CDS using SLIMS for Sample Management</strong></h5>
<p>Learn how SLIMS can be used in conjunction with Agilent’s OpenLab CDS for digitalizing your lab operations with an overview of the entire system and a demonstration.</p>
<h5><strong>2. Agilent Technologies: 2021 Agilent Science and Technology Virtual Symposium</strong></h5>
<p>Advancing Science Together. Innovation in life science and applied chemicals with you in mind. ASTvS 2021 is live across several continents.</p>
<h5><strong>3. New Food magazine/Metrohm International: Improving your analytics for beverage analysis with ion chromatography</strong></h5>
<p>We will begin with an overview of the latest analytical techniques used for beverage analyses and the presenters will then take a closer look at the benefits of ion chromatography for beverage analysis.</p>
<h5><strong>4. Mestrelab Research: Semi-automated LC-MS interpretation of DNA conjugates in 96 or 384 well plates</strong></h5>
<p>Roberto Martinez from Novartis (Basel) will give you a short introduction to the QC Profiling plugin, for semi-automated LCMS interpretations of DNA conjugates.</p>
<h5><strong>5. Agilent Technologies: LCMS Big Data: Experimental Design, Data Processing, and Alignment</strong></h5>
<p>This webinar will focus on Qualitative Analysis 10 and Profinder 10 and how these two software programs are connected and crucial to scientist’s workflows.</p>
<h5><strong>6. Agilent Technologies: Why Good Chromatography Matters for LCMS</strong></h5>
<p>This introduction webinar starts at the beginning by illustrating the optimal configuration of LC modules and LC capillary tubing to ensure lowest peak broadening to take place prior to MS detection.</p>
<h5><strong>7. SelectScience/Waters Corporation: Enhancing LC-MS analysis of oligos, peptides, and glycans using hybrid surface technology</strong></h5>
<p>In this webinar, a team of scientists from Waters Corporation will describe the benefits of the ACQUITY PREMIER Solution with MaxPeak HPS Technology in mitigating problematic metal interactions. </p>


LC and LCMS webinars - Week 18

<p><strong>In the week from May 10, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>900 LC and GC webinars</strong>.</p>
<h5><strong>1. SelectScience/Waters Corporation: Bioanalytical method development for oligonucleotides: Overcoming the analytical challenges</strong></h5>
<p>In this webinar, Mary Trudeau, principal applications scientist at Waters Corporation, will outline the key challenges in method development for oligonucleotides and solutions to address them. </p>
<h5><strong>2. Separation Science/Biotage: Perfecting Pcats – Developing a More Robust UHPLC-MS/MS Method for Plasma Catecholamines using Low Volume SPE</strong></h5>
<p>This webinar will discuss typical plasma matrices and the effects of different sample pre-treatments.</p>
<h5><strong>3. Waters Corporation: Get Prepared for Lipidomics 2.0 with Waters</strong></h5>
<p>In this webinar series we will discuss some of the latest analytical approaches which have been developed to address hurdles in Lipidomics.</p>
<h5><strong>4. Agilent Technologies: Robust and Reproducible Protein Quantification in Plasma using Evosep One and Agilent 6495 LC/TQ</strong></h5>
<p>Here we showcase the reproducibility, robustness, and analytical sensitivity of LC/MS/MS analysis of human plasma proteins using the Evosep One LC system and Agilent 6495 LC/QQQ with an nanospray source.</p>
<h5><strong>5. Waters Corporation: Meet the Experts - Part 2 - Flexible Service and Support Plans</strong></h5>
<p>Andy will present the latest service and support solutions from Waters giving you control over the options that best fit your laboratories’ unique needs.​</p>
<h5><strong>6. Separation Science/Agilent Technologies: Analysis of PFAS: Strategies to Optimize Performance</strong></h5>
<p>Separation Science, in collaboration with Agilent, offers an expert discussion forum addressing some of the key issues surrounding the targeted analysis of PFAS in environmental matrices.</p>
<h5><strong>7. New Food magazine/SCIEX: What can sensitivity give you other than lower LOQs?</strong></h5>
<p>In this webinar, Robert DiLorenzo demonstrates the various advantages of next-level sensitivity using the SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP® Ready with multiple contaminant testing case studies.</p>
<h5><strong>8. Thermo Fisher Scientific: Cell Culture Media Metabolite Profiling Using HRAM LCMS Approach</strong></h5>
<p>Here we demonstrate that a LC-high resolution Orbitrap MS platform can be used for multiple classes of cell culture media metabolite profiling with high sensitivity, high selectivity and high throughput.</p>
<h5><strong>9. Waters Corporation: eChalk Talk: Routine Accurate Mass Detection for Forced Degradation Studies</strong></h5>
<p>In this eChalk Talk, we will look at how a French CRO successfully implemented new technologies to improve analytical development services for their customers. </p>
<h5><strong>10. Agilent Technologies: Fundamentals of Turning Liquid Into Ions: The basics of Agilent LCMS ion sources and how to choose the best source for your Compounds</strong></h5>
<p>One of the major fears in using LCMS from LC/UV is choosing the correct Atmospheric Ionization Source (API) for turning analytes in liquid into ions in the gas phase. </p>
<h5><strong>11. SelectScience/MOBILion Systems: Large molecules get SLIM: High-Resolution Ion Mobility for simplifying complex large molecule characterization</strong></h5>
<p>How can High-Resolution Ion Mobility mass spectrometry (HRIM-MS) address the challenges of large molecule characterization?</p>


LC and LCMS webinars - Week 19

<p><strong>In the week from May 17, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>1 000 LC and GC webinars</strong>.</p>
<h5><strong>1. Thermo Fisher Scientific: Sample Preparation in Ion Chromatography</strong></h5>
<p>This presentation will review sample filtration and preservation, dilution, preconcentration and calibration, pretreatment cartridges for off-line or in-line matrix elimination, and neutralization.</p>
<h5><strong>2. Thermo Fisher Scientific: Impurity Analysis Roundtable</strong></h5>
<p>We will cover the importance of impurity testing at various stages of the manufacturing process, as well as enabling technologies to help make the analysis comprehensive, robust and compliant.</p>
<h5><strong>3. Separation Science/Merck: Sample Preparation for Fatty and Complex Food Matrices</strong></h5>
<p>This educational webinar is brought to you in collaboration with the Life Science business of Merck KGaA, Darmstadt, Germany.</p>
<h5><strong>4. Thermo Fisher Scientific: Applications of Ion Chromatography in the Detergent and Household Product Industry</strong></h5>
<p>In this presentation, representative examples of analytical methods for the analysis of detergent and household products are shown, demonstrating the versatility of ion chromatography.</p>
<h5><strong>5. Agilent Technologies: Increasing MS Productivity: A &quot;Self-Driving&quot; Mass Spectrometer Designed for Non-MS Experts</strong></h5>
<p>Join us to learn about the newest single quad in Agilent’s portfolio and how enhanced hardware and software features reduce the stress when migrating UHPLC UV Methods to MS detection.</p>
<h5><strong>6. Thermo Fisher Scientific: Applications of Ion Chromatography in the Petrochemical Industry</strong></h5>
<p>The schematic of a combustion IC system is shown as well as sulfur analysis in a liquefied petroleum gas sample as an application example.</p>
<h5><strong>7. Agilent Technologies: Virtual AssayMAP User Group Meeting</strong></h5>
<p>Take this unique opportunity to connect with other users and discover how they are applying the technology to meet their scientific challenges.</p>
<h5><strong>8. Agilent Technologies: Raise Your Nutraceutical iQ with the Agilent InfinityLab LC/MSD iQ</strong></h5>
<p>This webinar gives an overview of the role of single quad LC/MS in a Nutraceutical workflow. In addition, screening for pesticides such as Glyphosate in products will be demonstrated.</p>
<h5><strong>9. Phenomenex: Decrypting Liquid Chromatography Variation - Achieving Reproducibility in Results</strong></h5>
<p>This webinar will cover: Chromatographic variation and Instigating factors, Instrumental factors, Column, Stationary phase, Mobile phase...</p>
<h5><strong>10. Thermo Fisher Scientific: Applications of Ion Chromatography in the Pharmaceutical/Biotech Industry</strong></h5>
<p>In this presentation, isocratic and gradient IC separations relevant to the pharmaceutical/biotech industry will be discussed.  </p>
<h5><strong>11. Agilent Technologies: LCMS the Basics: Matching the Performance of the LCMS to Analytical Solutions</strong></h5>
<p>In this webinar we start reviewing the basics of LCMS single quadruple mass spectrometry, how the system functions and provided molecular weight information not available just using LC/UV detection.</p>
<h5><strong>12. SelectScience/Agilent Technologies: Meet regulatory compliance for biopharma with new mass spec software solutions</strong></h5>
<p>Explore how new mass spectrometry software updates can enable you to address data integrity and meet regulatory requirements, such as US FDA 21 CFR Part 11 and EU Annex 11.</p>


LC and LCMS webinars - Week 20

<p><strong>In the week from May 24, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>1 000 LC and GC webinars</strong>.</p>
<h5><strong>1. Institute of Biotechnology of the Czech Academy of Sciences: Instruct-ERIC course in Biophysics, structural mass spectrometry, and X-ray techniques</strong></h5>
<p>The course will provide basic and applied training in a range of selected methods of integrative structural biology. </p>
<h5><strong>2. Waters Corporation: Pharma in MOTION - Day 1: Protein and Peptide Bioanalysis</strong></h5>
<p>Join Waters and our panel of industry experts for this special, first edition of Pharma in MOTION - Protein and Peptide Bioanalysis.</p>
<h5><strong>3. Phenomenex: Strategies for Improving Chromatographic Resolution</strong></h5>
<p>This presentation will look at some of the solutions to modern day chromatographic challenges for polar compounds. </p>
<h5><strong>4. Waters Corporation: Pharma in MOTION - Day 2: Technologies &amp; Protein Analysis</strong></h5>
<p>Join Waters and our panel of industry experts for this special, first edition of Pharma in MOTION - Technologies &amp; Protein Analysis.</p>
<h5><strong>5. Waters Corporation: Strategies for mycotoxin testing – analytical perspectives from field to lab</strong></h5>
<p>This webinar presents strategies to detect and determine mycotoxins from the field to the lab.</p>
<h5><strong>6. Agilent Technologies: Absolute and Relative Quantitation for Targeted Metabolomics and Lipidomics</strong></h5>
<p>In this presentation we show absolute quantitation of fragile metabolites using the dMRM method and incorporating isotope dilution mass spectrometry (IDMS).</p>
<h5><strong>7. Waters Corporation: Pharma in MOTION - Day 3: Analytical Method Development (AQbD) &amp; Oligonucleotide Analysis</strong></h5>
<p>Join Waters and our panel of industry experts for this special, first edition of Pharma in MOTION - Analytical Method Development (AQbD) &amp; Oligonucleotide Analysis.</p>
<h5><strong>8. Technology Networks/Bruker: LC-MS Meets MS Imaging: Using CCS for Confident Lipid Annotation</strong></h5>
<p>TIMS for the separation of ions after MALDI has become a useful tool in lipid research, increasing the reliability of lipid identification using complementary collision cross section (CCS) data.</p>
<h5><strong>9. Agilent Technologies: LC/MS and Software Solutions for Your Metabolomic Studies</strong></h5>
<p>This webinar will focus on the latest tools for a metabolomics lab to answer your research questions with ease.</p>
<h5><strong>10. Waters Corporation: Per-and Polyfluoronated Alkyl Substances (PFAS) and the Challenges in Development of a Direct Injection Method by UPLC-MS/MS</strong></h5>
<p>An objective to develop a direct injection method utilizing the ACQUITY I-Class and Xevo TQ-XS was set.</p>
<h5><strong>11. Agilent Technologies: Helpful ‘hints’ for Protein SEC Success</strong></h5>
<p>This webinar will provide key guidelines for successful SEC method development.</p>
<h5><strong>12. Waters Corporation: Pharma in MOTION - Day 4: Biophysical Characterization</strong></h5>
<p>Join Waters and our panel of industry experts for this special, first edition of Pharma in MOTION - Biophysical Characterization</p>
<h5><strong>13. Evosep Biosystems: Unleashing the power of DIA combined with short gradients using the Evosep One</strong></h5>
<p>In this webinar will discuss the practical application of DIA, generating record number is ID’s per minute, using the speed of Evosep One’s fast chromatography methods.</p>
<h5><strong>14. Separation Science/SCIEX: Analytical Methodologies for Nitrosamines: Challenges and Solutions</strong></h5>
<p>Separation Science, in collaboration with SCIEX, presents a webinar that will cover analytical methodologies for N-nitrosamines in pharmaceuticals with their challenges and suggested solutions.</p>
<h5><strong>15. SelectScience/Agilent Technologies: Pioneers in biopharma: Meet the leaders steering the industry on a path that celebrates and supports women</strong></h5>
<p>These webinars highlight research and development in process analytical technologies, development of novel modalities, and the integration of emerging technologies to the field of mass spectroscopy.</p>
<h5><strong>16. C&amp;EN/Metrohm: From Extraction to Injection, The Journey of Complex Food Ingredients</strong></h5>
<p>In this webinar will give perspective on how to evaluate the sample matrix when you’re using ion chromatography and we will talk also about the latest advancements in ion chromatography. </p>
<h5><strong>17. Agilent Technologies: Eliminate the Fear in Agilent LC/MS System Maintenance &amp; Troubleshooting</strong></h5>
<p>In this talk, Agilent’s LC/MS Regional System Specialists will discuss several topics that will help eliminate the fear factor of LC/MS by providing best practices and troubleshooting tricks and tips.</p>


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LC and LCMS webinars - Week 21

LC and LCMS webinars - Week 20

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LC and LCMS webinars - Week 17

LC/MS Unknown Identifications Using MSMS Libraries Part VI: MS Interpreter Correlation of Substructure to MSMS Ions

LC and LCMS webinars - Week 16

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LC and LCMS webinars - Week 13

Upcoming events

36th MassSpec Forum Vienna 2026

Analytical Strategies for Peptide & Protein Therapeutics

Advance Your SEC Knowledge Scientific Hands-on Workshop

Webinars

Understanding and Applying USP Chapter 621 for Generic Pharmaceutical Applications

Genome integrity analysis of adeno-associated viruses (AAV) by genome sizing methodology using SCIEX capillary electrophoresis system

The Gold Standard: Achieving Optimal Peptide Purification with Reversed-Phase Chromatography