This study demonstrates Orbitrap-based CDMS/Direct Mass Technology as a quantitative tool for resolving and analyzing heterogeneous protein complexes below 100 kDa.

Scientists at IOCB Prague reveal a previously unknown mechanism that initiates gene transcription. Using cryo-EM, they uncover how alarmone molecules enable RNA synthesis under stress.

Two outstanding early-career researchers at UCT Prague, Filipa Oliveira and Stella Gonsales, received prestigious GAČR JUNIOR STAR grants for innovative research in materials science and sustainable chemistry.

This study demonstrates Orbitrap-IRMS for full and intramolecular carbon isotope analysis of PFOA, enabling sensitive PFAS source fingerprinting without analyte decomposition.

Dwight Stoll explains why chromatography needs big, high-quality retention datasets for AI—how short columns boost throughput, why ratios matter, and why “drifty” phases threaten prediction models.

This study couples LC to ESI-Orbitrap MS for stable isotope analysis using peak homogenization to remove chromatographic isotope effects and amount dependency, achieving precise C, N, and S isotopologue ratios.

Interview with Dr. Eamonn Clark on WRRC water research, fuel-spill impacts, PFAS workflows, and how DIY tools like a homebuilt nitrogen evaporator can expand low-resource labs.

Researchers at IOCB Prague have developed new fluorogenic labels that deliver high-contrast fluorescence microscopy, enabling precise visualization of cellular processes without background noise.

Structure-guided libraries and machine learning enable faster discovery of active nucleic acid sequences beyond random mutagenesis.

A Czech study shows BPA exposure has declined over the past decade, but remains above safe limits. Meanwhile, BPS levels are rising, proving that “BPA-free” products are not risk-free.