Gunacins, new compounds from Exobasidium, display strong anti-Leishmania and anti-Trypanosoma effects and also show antibacterial and antifungal activity.

Researchers at IOCB Prague developed a highly precise and ultra-stable fluorescent labeling method that stays attached even inside cells, enabling long-term, reliable tracking of biomolecules.

A fast HPLC-UV method was optimized to quantify trigonelline, 5-CQA, and caffeine in multiple Arabica cultivars. The method proved robust and highlighted major cultivar and roasting-related changes.

RECETOX researchers showed that some flame retardants in car interiors rise up to 700× in summer compared to winter, revealing strong temperature-driven exposure risks for drivers and passengers.

Copper/PVA films showed strong visible-light antiviral activity against MHV-3. Films with copper microparticles reduced viral load by 43% under illumination, compared with minimal reduction in the dark.

HPLC-HRMS with chemometrics showed clear metabolomic changes in herbicide-treated rice, including reduced sugars, lower flavonoids, and disrupted phenylpropanoid pathways.

This study presents a multimethod strategy to quantify citrate ligands on iron oxide nanoparticles using TGA, CHN, qNMR, and RP-HPLC, showing how selective methods improve accuracy and prevent overestimation.

IOCB Prague scientists have developed light-driven molecular motors that remain fully functional even when anchored to metal surfaces, marking a major step toward controllable nanoscale machines.

Regenerating liver redirects ammonia metabolism to fuel de novo pyrimidine synthesis, enabling cell proliferation and tissue repair after hepatectomy through metabolic reprogramming.

A new class of trisubstituted pyridines targets ATP synthase in Acinetobacter baumannii. Four lead compounds showed potent antibacterial effects and synergized with colistin against multidrug-resistant strains.