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Rapid Multi-Omics for Bacterial Identification Using Flow Injection–Ion Mobility–Mass Spectrometry
Scientific article | Science and research

Rapid Multi-Omics for Bacterial Identification Using Flow Injection–Ion Mobility–Mass Spectrometry

Flow-injection ion mobility MS enables rapid multi-omics profiling of bacterial pathogens. It matches LC-IM-MS performance, cuts analysis time from 17 to 2 min.
Mo, 18.8.2025
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Rapid Multi-Omics for Bacterial Identification Using Flow Injection–Ion Mobility–Mass Spectrometry
Quantification of Endogenous Steroids and Hormonal Contraceptives in Human Plasma via Surrogate Calibration and UHPLC-MS/MS
Scientific article | Science and research

Quantification of Endogenous Steroids and Hormonal Contraceptives in Human Plasma via Surrogate Calibration and UHPLC-MS/MS

A UHPLC-MS/MS assay using surrogate calibration and DMIS derivatization quantifies endogenous steroids and contraceptives in plasma with pg/mL sensitivity and regulatory-aligned validation.
Mo, 11.8.2025
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Quantification of Endogenous Steroids and Hormonal Contraceptives in Human Plasma via Surrogate Calibration and UHPLC-MS/MS
Controllable Ion-Repulsion Enables Rapid and Trace-Level Detection of Hydrophobic Sulfonylurea Herbicides with ICPMS/MS without the Organic Mode
Scientific article | Science and research

Controllable Ion-Repulsion Enables Rapid and Trace-Level Detection of Hydrophobic Sulfonylurea Herbicides with ICPMS/MS without the Organic Mode

A novel ion-repulsion strategy allows rapid ICPMS/MS detection of hydrophobic sulfonylureas with minimal organic solvent, achieving high sensitivity and bypassing the need for organic ICPMS mode.
Mo, 4.8.2025
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Controllable Ion-Repulsion Enables Rapid and Trace-Level Detection of Hydrophobic Sulfonylurea Herbicides with ICPMS/MS without the Organic Mode
Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics
Scientific article | Science and research

Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics

A new dried plasma microsampling device enables home sampling with high precision and stability, correlating strongly (R > 0.99) with conventional plasma in targeted proteomic analysis.
Mo, 4.8.2025
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Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics
A facile and eco-friendly simultaneous quantification LC-TQ-MS/MS approach for N-Nitroso Moxifloxacin and di-nitroso pyrrolopiperidine in Moxifloxacin tablets and eye drops
Scientific article | Science and research

A facile and eco-friendly simultaneous quantification LC-TQ-MS/MS approach for N-Nitroso Moxifloxacin and di-nitroso pyrrolopiperidine in Moxifloxacin tablets and eye drops

A rapid, green LC-QqQ-MS/MS method quantifies N-MOX and DNPP in moxifloxacin tablets and eye drops. Validated per ICH, it ensures safety by detecting trace NDSRIs with minimal environmental impact.
Mo, 28.7.2025
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A facile and eco-friendly simultaneous quantification LC-TQ-MS/MS approach for N-Nitroso Moxifloxacin and di-nitroso pyrrolopiperidine in Moxifloxacin tablets and eye drops
A novel LC-TQ-MS/MS method for quantifying mefenamic acid-NDSRI (N-nitroso drug substance-related impurity) in mefenamic acid tablet and pediatric suspension dosage forms: a comparative study with a cost-effective white, green, and blue UPLC method
Scientific article | Science and research

A novel LC-TQ-MS/MS method for quantifying mefenamic acid-NDSRI (N-nitroso drug substance-related impurity) in mefenamic acid tablet and pediatric suspension dosage forms: a comparative study with a cost-effective white, green, and blue UPLC method

Novel LC-MS/MS and UPLC methods quantify NDSRI in mefenamic acid tablets and suspensions with high sensitivity, accuracy, and eco-friendly evaluation via multiple green metrics.
Mo, 21.7.2025
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A novel LC-TQ-MS/MS method for quantifying mefenamic acid-NDSRI (N-nitroso drug substance-related impurity) in mefenamic acid tablet and pediatric suspension dosage forms: a comparative study with a cost-effective white, green, and blue UPLC method
Systematic method optimisation approach for small molecule imaging on the SELECT SERIES MALDI MRT - Drug mapping in fingerprints, a case study
Scientific article | Science and research

Systematic method optimisation approach for small molecule imaging on the SELECT SERIES MALDI MRT - Drug mapping in fingerprints, a case study

MALDI-MSI on SELECT SERIES MALDI-MRT was optimized for fingerprint imaging. The method improves resolution and enables detection of drugs like antipsychotics in latent prints.
Mo, 14.7.2025
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Systematic method optimisation approach for small molecule imaging on the SELECT SERIES MALDI MRT - Drug mapping in fingerprints, a case study
Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products
Scientific article | Science and research

Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products

This study aims to develop and validate a rapid IC-ICP-MS method for identifying and quantifying polyphosphonates and their transformation products under environmental conditions.
Mo, 7.7.2025
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Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products
Occurrence of Pharmaceuticals and Other Anthropogenic Compounds in the Wastewater Effluent of Arctic Expedition Cruise Ships
Scientific article | Science and research

Occurrence of Pharmaceuticals and Other Anthropogenic Compounds in the Wastewater Effluent of Arctic Expedition Cruise Ships

The study examines treated wastewater from Arctic cruise ships to identify pharmaceuticals and other contaminants, highlighting potential risks to sensitive polar marine environments.
Mo, 7.7.2025
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Occurrence of Pharmaceuticals and Other Anthropogenic Compounds in the Wastewater Effluent of Arctic Expedition Cruise Ships
NDMA in macrolides: GC-MS/MS method for its detection and study of its formation
Scientific article | Science and research

NDMA in macrolides: GC-MS/MS method for its detection and study of its formation

This study evaluates the risk of NDMA formation from macrolide antibiotics, highlighting solubility-related analytical challenges and the role of drug form and storage in NDMA levels.
Mo, 7.7.2025
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NDMA in macrolides: GC-MS/MS method for its detection and study of its formation
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LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike