A semisynthetic method enabled the preparation of stable isotope-labeled ergot alkaloids for precise HPLC-MS/MS quantification.

Suspect screening using LC- and GC-HRMS identified 547 chemicals across environmental, food, and human samples. Pharmaceuticals, pesticides, and personal care products were the most frequent contaminants.

Czech researchers developed carbon-dot nanosensors that precisely measure pH inside living cells. The technology offers stable, calibration-free fluorescence detection for biomedical use.

A VESI-MS strategy allows real-time monitoring of redox processes, enabling rational pulse design for selective decarboxylative hydroxylation using only O₂, water, and carbon electrodes.

A sustainable synthesis combining mechanochemistry and chemical aging yields defect-rich bismuth oxide nanosheets with excellent adsorption and photocatalytic performance toward persistent organic pollutants.

Researchers developed a compact, disposable 3D-printed “Lab-on-a-Scalpel” for on-site chemical analysis during surgery. The device detects biomarkers like epinephrine with high sensitivity.

Wide-pore SEC columns for rAAV and mRNA were systematically compared. DNACore AAV-SEC and Biozen dSEC-7 offered the best efficiency, guiding optimal gene therapy product characterization.

The review compiles R and Python tools for analyzing lipidomics and metabolomics data, guiding beginners to create publication-ready graphics and enabling robust, reproducible chemometric analysis.

UPCE scientists co-authored a Nature Communications paper presenting best practices in R and Python for statistical processing and visualization of lipidomics and metabolomics data.

This study introduces acrylamide monolith HILIC-MS for intact mAb glycoprofiling, offering high selectivity, baseline separation, and detection of low-abundance glycoforms missed by RPLC-MS.