A facile and eco-friendly simultaneous quantification LC-TQ-MS/MS approach for N-Nitroso Moxifloxacin and di-nitroso pyrrolopiperidine in Moxifloxacin tablets and eye drops
Scientific article | Science and research

A facile and eco-friendly simultaneous quantification LC-TQ-MS/MS approach for N-Nitroso Moxifloxacin and di-nitroso pyrrolopiperidine in Moxifloxacin tablets and eye drops

A rapid, green LC-QqQ-MS/MS method quantifies N-MOX and DNPP in moxifloxacin tablets and eye drops. Validated per ICH, it ensures safety by detecting trace NDSRIs with minimal environmental impact.
Mo, 28.7.2025
LabRulez
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A facile and eco-friendly simultaneous quantification LC-TQ-MS/MS approach for N-Nitroso Moxifloxacin and di-nitroso pyrrolopiperidine in Moxifloxacin tablets and eye drops
A novel LC-TQ-MS/MS method for quantifying mefenamic acid-NDSRI (N-nitroso drug substance-related impurity) in mefenamic acid tablet and pediatric suspension dosage forms: a comparative study with a cost-effective white, green, and blue UPLC method
Scientific article | Science and research

A novel LC-TQ-MS/MS method for quantifying mefenamic acid-NDSRI (N-nitroso drug substance-related impurity) in mefenamic acid tablet and pediatric suspension dosage forms: a comparative study with a cost-effective white, green, and blue UPLC method

Novel LC-MS/MS and UPLC methods quantify NDSRI in mefenamic acid tablets and suspensions with high sensitivity, accuracy, and eco-friendly evaluation via multiple green metrics.
Mo, 21.7.2025
LabRulez
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A novel LC-TQ-MS/MS method for quantifying mefenamic acid-NDSRI (N-nitroso drug substance-related impurity) in mefenamic acid tablet and pediatric suspension dosage forms: a comparative study with a cost-effective white, green, and blue UPLC method
Systematic method optimisation approach for small molecule imaging on the SELECT SERIES MALDI MRT - Drug mapping in fingerprints, a case study
Scientific article | Science and research

Systematic method optimisation approach for small molecule imaging on the SELECT SERIES MALDI MRT - Drug mapping in fingerprints, a case study

MALDI-MSI on SELECT SERIES MALDI-MRT was optimized for fingerprint imaging. The method improves resolution and enables detection of drugs like antipsychotics in latent prints.
Mo, 14.7.2025
LabRulez
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Systematic method optimisation approach for small molecule imaging on the SELECT SERIES MALDI MRT - Drug mapping in fingerprints, a case study
Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products
Scientific article | Science and research

Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products

This study aims to develop and validate a rapid IC-ICP-MS method for identifying and quantifying polyphosphonates and their transformation products under environmental conditions.
Mo, 7.7.2025
LabRulez
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Comprehensive IC-ICP-MS analysis of polyphosphonates and their transformation products
Occurrence of Pharmaceuticals and Other Anthropogenic Compounds in the Wastewater Effluent of Arctic Expedition Cruise Ships
Scientific article | Science and research

Occurrence of Pharmaceuticals and Other Anthropogenic Compounds in the Wastewater Effluent of Arctic Expedition Cruise Ships

The study examines treated wastewater from Arctic cruise ships to identify pharmaceuticals and other contaminants, highlighting potential risks to sensitive polar marine environments.
Mo, 7.7.2025
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Occurrence of Pharmaceuticals and Other Anthropogenic Compounds in the Wastewater Effluent of Arctic Expedition Cruise Ships
NDMA in macrolides: GC-MS/MS method for its detection and study of its formation
Scientific article | Science and research

NDMA in macrolides: GC-MS/MS method for its detection and study of its formation

This study evaluates the risk of NDMA formation from macrolide antibiotics, highlighting solubility-related analytical challenges and the role of drug form and storage in NDMA levels.
Mo, 7.7.2025
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NDMA in macrolides: GC-MS/MS method for its detection and study of its formation
Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets
Scientific article | Science and research

Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets

This study aimed to develop and compare ten extraction protocols to find the most effective method for generating metabolomics, lipidomics, and proteomics data from postmortem tissue.
Mo, 30.6.2025
LabRulez
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Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets
Publication in Nature Microbiology describes a new type of light-harvesting apparatus in marine archaea
Scientific article | Science and research

Publication in Nature Microbiology describes a new type of light-harvesting apparatus in marine archaea

An international team discovered a new light-harvesting system in marine Asgard archaea: rhodopsins with carotenoid antennas that enhance light absorption and ATP generation in ocean environments.
Th, 26.6.2025
Czech Academy of Sciences
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Publication in Nature Microbiology describes a new type of light-harvesting apparatus in marine archaea
Advanced LC-MS/MS method for selective quantification of nitrosamine impurities in Risperidone: Enhancing drug safety
Scientific article | Science and research

Advanced LC-MS/MS method for selective quantification of nitrosamine impurities in Risperidone: Enhancing drug safety

The study presents a validated LC-MS/MS method for rapid and accurate quantification of four nitrosamine impurities in Risperidone, supporting enhanced impurity monitoring and quality control.
Mo, 23.6.2025
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Advanced LC-MS/MS method for selective quantification of nitrosamine impurities in Risperidone: Enhancing drug safety
New study reveals how textiles trap harmful chemicals
Scientific article | Science and research

New study reveals how textiles trap harmful chemicals

The latest research of scientists from RECETOX reveals how various fabrics absorb and release harmful aromatic amines (AAs) compounds linked to cancer and other health risks.
Tu, 17.6.2025
RECETOX - Centrum pro výzkum toxických látek v prostředí
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New study reveals how textiles trap harmful chemicals
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