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Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS
Scientific article | Science and research

Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS

This study presents an HPLC-ICP-MS method for precise quantification of Gd complexes in Gadoquatrane, enabling detection of trace by-products to optimize synthesis and drug control strategies.
Mo, 17.3.2025
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Quantification of Gd species in a tetrameric Gd-based contrast agent using HPLC-ICP-MS
Evaluating the potential of hydrophilic interaction liquid chromatography for collagen peptide mapping analysis
Scientific article | Science and research

Evaluating the potential of hydrophilic interaction liquid chromatography for collagen peptide mapping analysis

This study optimizes a HILIC method for collagen peptide mapping, evaluating stationary phases, injection techniques, and MS coupling to enhance peptide separation and hydroxylation analysis.
Mo, 17.3.2025
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Evaluating the potential of hydrophilic interaction liquid chromatography for collagen peptide mapping analysis
High-throughput mercury speciation analysis of breast milk using HPLC-ICP-MS
Scientific article | Health

High-throughput mercury speciation analysis of breast milk using HPLC-ICP-MS

This study developed an HPLC-ICP-MS method to quantify Hg²⁺ and MeHg⁺ in breast milk, evaluating collection methods, total mercury correlation, and elemental associations in samples over a 4-month study.
Mo, 10.3.2025
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High-throughput mercury speciation analysis of breast milk using HPLC-ICP-MS
Impact of mobile and stationary phases on siRNA duplex stability in liquid chromatography
Scientific article | Various

Impact of mobile and stationary phases on siRNA duplex stability in liquid chromatography

This study investigates how mobile phases and chromatographic conditions affect siRNA duplex stability, using DSC and chromatography to measure melting temperatures.
Mo, 10.3.2025
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Impact of mobile and stationary phases on siRNA duplex stability in liquid chromatography
Solving the retention time repeatability problem of hydrophilic interaction liquid chromatography
Scientific article | Various

Solving the retention time repeatability problem of hydrophilic interaction liquid chromatography

This study identifies ion release from borosilicate glass bottles as a cause of poor HILIC retention time repeatability and proposes PFA bottles as a solution.
Mo, 3.3.2025
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Solving the retention time repeatability problem of hydrophilic interaction liquid chromatography
Coupling of Size Exclusion Chromatography to High Throughput Charge Detection Mass Spectrometry for the Analysis of Large Proteins and Virus-like Particles
Scientific article | Science and research

Coupling of Size Exclusion Chromatography to High Throughput Charge Detection Mass Spectrometry for the Analysis of Large Proteins and Virus-like Particles

This study enhances SEC-CD-MS for high-mass analysis by integrating high-throughput CD-MS and ultrawidepore SEC, enabling precise characterization of large biomolecules like VLPs and monoclonal antibodies.
Tu, 25.2.2025
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Coupling of Size Exclusion Chromatography to High Throughput Charge Detection Mass Spectrometry for the Analysis of Large Proteins and Virus-like Particles
Remote Deep-Ultraviolet Laser Ablation in Connection with Electrospray Ionization–Atmospheric Pressure Chemical Ionization (rDUVLAESCI): A Novel Dual Ionization Source for Molecular Mass Spectrometry
Scientific article | Science and research

Remote Deep-Ultraviolet Laser Ablation in Connection with Electrospray Ionization–Atmospheric Pressure Chemical Ionization (rDUVLAESCI): A Novel Dual Ionization Source for Molecular Mass Spectrometry

This study introduces a novel remote deep-UV laser ablation dual-ionization source for molecular mass spectrometry and imaging with enhanced spatial resolution.
Tu, 18.2.2025
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Remote Deep-Ultraviolet Laser Ablation in Connection with Electrospray Ionization–Atmospheric Pressure Chemical Ionization (rDUVLAESCI): A Novel Dual Ionization Source for Molecular Mass Spectrometry
Staining Tissues with Basic Blue 7: A New Dual-Polarity Matrix for MALDI Mass Spectrometry Imaging
Scientific article | Science and research

Staining Tissues with Basic Blue 7: A New Dual-Polarity Matrix for MALDI Mass Spectrometry Imaging

This study presents Basic Blue 7 (BB7) as a novel dual-polarity matrix for MALDI MSI, offering a simple, cost-effective sample prep method that improves image quality and reproducibility.
Tu, 11.2.2025
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Staining Tissues with Basic Blue 7: A New Dual-Polarity Matrix for MALDI Mass Spectrometry Imaging
Synthesis and absolute configuration of cyclic synthetic cathinones derived from α-tetralone
Scientific article | Various

Synthesis and absolute configuration of cyclic synthetic cathinones derived from α-tetralone

The goal of this study is to design, synthesize, and characterize novel cyclic α-tetralone-based synthetic cathinones and determine their absolute configurations.
Tu, 28.1.2025
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Synthesis and absolute configuration of cyclic synthetic cathinones derived from α-tetralone
Personalized Profiling of Lipoprotein and Lipid Metabolism Based on 1018 Measures from Combined Quantitative NMR and LC-MS/MS Platforms
Scientific article | Various

Personalized Profiling of Lipoprotein and Lipid Metabolism Based on 1018 Measures from Combined Quantitative NMR and LC-MS/MS Platforms

The goal of this study is to integrate and analyze large-scale lipoprotein and lipidomics data for understanding molecular epidemiology and cardiometabolic risk.
Tu, 21.1.2025
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Personalized Profiling of Lipoprotein and Lipid Metabolism Based on 1018 Measures from Combined Quantitative NMR and LC-MS/MS Platforms
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LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike