Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (“Nearby Precursors” Enhancement)
Article | Video

Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (“Nearby Precursors” Enhancement)

Part 1A discusses the using the "Nearby Precursor" to easily display a MSMS spectrum associated with an ion in MS.
Th, 20.3.2025
James Little/Mass Spec Interpretation Services
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Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (“Nearby Precursors” Enhancement)
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (NIST Search Type Demonstration)
Article | Video

Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (NIST Search Type Demonstration)

This course shows how to identify unknowns in LCMS analysis by the NIST MSMS search software. Part 4 demonstrates 3 different type searches for MSMS data within the NIST2023 search software.
Fr, 14.3.2025
James Little/Mass Spec Interpretation Services
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Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (NIST Search Type Demonstration)
 Data Processing for NIST MSMS Search Using Thermo Freestyle Software (My Favorite Approach)
Article | Video

Data Processing for NIST MSMS Search Using Thermo Freestyle Software (My Favorite Approach)

This part discusses my favorite approach for processing Orbitrap LCMS/LCMSMS data for identificaiton of unknowns using the NIST2023 search and associated libraries.
Th, 6.2.2025
James Little/Mass Spec Interpretation Services
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 Data Processing for NIST MSMS Search Using Thermo Freestyle Software (My Favorite Approach)
Using NIST MS Search with Agilent OpenLab Software for Unknown Identifications
Article | Academy

Using NIST MS Search with Agilent OpenLab Software for Unknown Identifications

Agilent’s OpenLab Software can easily be employed with NIST 2023 Search and associated libraries for unknown identifications.
Th, 23.1.2025
James Little/Mass Spec Interpretation Services
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Using NIST MS Search with Agilent OpenLab Software for Unknown Identifications
What is Dead Volume in HPLC?
Article | Academy

What is Dead Volume in HPLC?

Most people who ask about dead volume actually want to know how much internal volume exists within the connection. What exactly is the matter with these terms?
Tu, 17.12.2024
Watrex Praha
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What is Dead Volume in HPLC?
Using Agilent MassHunter to Perform NIST MSMS Search
Article | Video

Using Agilent MassHunter to Perform NIST MSMS Search

This web page demonstrates the use of the Agilent MassHunter Software for processing MSMS data files.  The MSMS spectra are easily sent to the NIST MSMS Search program for identification.
Th, 17.10.2024
James Little/Mass Spec Interpretation Services
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Using Agilent MassHunter to Perform NIST MSMS Search
Advancing Fundamental Understanding of Retention Interactions in Supercritical Fluid Chromatography Using Artificial Neural Networks: Polar Stationary Phases with –OH Moieties
Article | Scientific article

Advancing Fundamental Understanding of Retention Interactions in Supercritical Fluid Chromatography Using Artificial Neural Networks: Polar Stationary Phases with –OH Moieties

The researchers used artificial neural networks to advance a fundamental understanding of retention interactions in supercritical fluid chromatography.
Tu, 24.9.2024
LabRulez
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Advancing Fundamental Understanding of Retention Interactions in Supercritical Fluid Chromatography Using Artificial Neural Networks: Polar Stationary Phases with –OH Moieties
Tips and tricks for LC–MS-based metabolomics and lipidomics analysis
Article | Scientific article

Tips and tricks for LC–MS-based metabolomics and lipidomics analysis

In the in Trends in Analytical Chemistry journal the researchers from the Institute of Physiology of the Czech Academy of Sciences, gave comprehensive overview of metabolomics and lipidomics tools.
Tu, 17.9.2024
LabRulez
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Tips and tricks for LC–MS-based metabolomics and lipidomics analysis
High-Throughput Chromatographic Separation of Oligonucleotides: A Proof of Concept Using Ultra-Short Columns
Article | Scientific article

High-Throughput Chromatographic Separation of Oligonucleotides: A Proof of Concept Using Ultra-Short Columns

In the in ACS Analytical Chemistry the researchers took a deep dive into understanding the retention mechanism of oligonucleotides, and evaluation of the linear solvent strength (LSS) retention model.
Tu, 3.9.2024
LabRulez
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High-Throughput Chromatographic Separation of Oligonucleotides: A Proof of Concept Using Ultra-Short Columns
Launch of the book: Modern HPLC separations in theory and practice
Article | Product

Launch of the book: Modern HPLC separations in theory and practice

This book is a unique combination of theory and practice, but also overviews of stationary phases, sample prep materials, and vendor’s brief presentations.
We, 26.6.2024
Česká chromatografická škola
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Launch of the book: Modern HPLC separations in theory and practice
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