A new project supported by the Czech Science Foundation (GACR) focuses on a detailed study of ions produced in electrospray and their potential use beyond analytical chemistry.

9 webinars: Oligos science, Pharma Impurities, Oligonucleotides, NDSRI analysis, pH measurements, Antibodies & LCMS, Polysaccharides & SEC, LC/MS/MS, Electrophoresis.

This study evaluates matrix effects in untargeted HILIC-MS plasma metabolomics using post-column infusion, identifying optimal conditions and improving method reliability for metabolite analysis.

This course shows how to identify unknowns in LCMS analysis employing the NIST MSMS search software. Part 3 discusses basic settings for Thermo Freestyle software and the NIST 2023 Search.

This week we bring you application notes by Agilent Technologies, Mestrelab Research, Shimadzu and Waters Corporation, poster by GC Image / MDCW and technical note by Thermo Fisher Scientific!

MD-LC-MS advances structural and functional analysis of mAbs, showing how post-translational changes impact FcRn/FcγR binding and antibody therapeutic performance.

Prof. Rafael Cela (Mestrelab) presents LC method selection with Mgears Chrom Best Method and how automation improves screening, analysis, reporting, and decisions.

Orbitrap-based MS revolutionizes intact protein analysis, surpassing TOF systems in resolution and robustness, enabling detailed glycoform studies and megaDalton protein insights.

5 webinars: Oligonucleotide purifications (AEX), Ideal SPE sorbent, Mass spectrometry-driven proteomics, Compact HPLC, PFAS in Drinking Water - Sampling.

This study uses HILIC-MS to explore how thorium interacts with phosphorylated biomimetic peptides, revealing its affinity and selectivity versus uranium for toxicity modeling.