This week we bring you application notes by Agilent Technologies, Shimadzu, Thermo Fisher Scientific and Waters Corporation!

Learn how to minimize peak tailing when analyzing basic compounds on type A silicas. Explore pH adjustment, mobile phase modifiers, and modern type B silica columns for sharper, more symmetrical peaks.

Learn how to manually recalibrate specific calibration levels for individual compounds using the Recalibration Mode and Add Peak functions to improve curve accuracy and analytical reliability.

Discover the new Thermo Scientific Vanquish CAD P Series – the next evolution in HPLC detection. Improved sensitivity, method transfer tools, and real-time optimization.

Discover how the scripting node in Thermo Scientific Compound Discoverer lets you run custom R or Python code directly in your workflow for tailored calculations, database links, and advanced data insights.

23 webinars: ADCs, AI, bioprocessing, chemoproteomics, DLS, LC-MS, PFAS, polar analytes, retrosynthesis, RNA, SEC, UHPLC, workflow automation

A new class of trisubstituted pyridines targets ATP synthase in Acinetobacter baumannii. Four lead compounds showed potent antibacterial effects and synergized with colistin against multidrug-resistant strains.

A semisynthetic method enabled the preparation of stable isotope-labeled ergot alkaloids for precise HPLC-MS/MS quantification.

Suspect screening using LC- and GC-HRMS identified 547 chemicals across environmental, food, and human samples. Pharmaceuticals, pesticides, and personal care products were the most frequent contaminants.

Graduate researcher Morgan from UNR discusses using ELISA and nitrogen evaporation to measure stress hormones in sheep, improving welfare and livestock resilience.