Get ready for Mbook 4.0! This release brings a sleek new interface, intuitive navigation, and advanced search filters - making ELN management more efficient, streamlined, and user-friendly.
We, 9.4.2025
SciY/Mestrelab Research
Article | Application
News from LabRulezLCMS Library - Week 15, 2025
This week we bring you application notes by Agilent Technologies, Shimadzu, Thermo Fisher Scientific and Waters Corporation!
We, 9.4.2025
LabRulez
Presentation | Video
Application of 2D-LC-MS for analysis of pharmaceutical peptides (Patrik Petersson, MDCW 2025)
2D-LC-MS improves peptide impurity profiling by enabling salt-based eluents, detecting co-eluting isomers, and solving challenges with shifting retention times.
We, 9.4.2025
The Multidimensional Chromatography Workshop
Article | Science and research
How to control ions? Dr. Michael Volný’s Czech Science Foundation project investigates new possibilities in mass spectrometry
A new project supported by the Czech Science Foundation (GACR) focuses on a detailed study of ions produced in electrospray and their potential use beyond analytical chemistry.
Matrix effect evaluation using multi-component post-column infusion in untargeted hydrophilic interaction liquid chromatography-mass spectrometry plasma metabolomics
This study evaluates matrix effects in untargeted HILIC-MS plasma metabolomics using post-column infusion, identifying optimal conditions and improving method reliability for metabolite analysis.
Mo, 7.4.2025
LabRulez
Article | Video
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (Setting Up NIST Search and Freestyle Parameters)
This course shows how to identify unknowns in LCMS analysis employing the NIST MSMS search software. Part 3 discusses basic settings for Thermo Freestyle software and the NIST 2023 Search.
Th, 3.4.2025
James Little/Mass Spec Interpretation Services
Article | Application
News from LabRulezLCMS Library - Week 14, 2025
This week we bring you application notes by Agilent Technologies, Mestrelab Research, Shimadzu and Waters Corporation, poster by GC Image / MDCW and technical note by Thermo Fisher Scientific!
We, 2.4.2025
LabRulez
Presentation | Video
MD-LC-MS for structure-function characterization of therapeutic antibodies (Jelle De Vos, MDCW 2025)
MD-LC-MS advances structural and functional analysis of mAbs, showing how post-translational changes impact FcRn/FcγR binding and antibody therapeutic performance.
We, 2.4.2025
The Multidimensional Chromatography Workshop
Article | Application
Scoring of LC separation procedures for ezetimibe and its degradants using Mgears Chrom Best Method
Prof. Rafael Cela (Mestrelab) presents LC method selection with Mgears Chrom Best Method and how automation improves screening, analysis, reporting, and decisions.