Modeling indirectly detected analyte peaks in ion-pair reversed-phase chromatography
This study models indirect detection using co- and counter-ion probes in chromatography. New isotherm models accurately predicted elution and sensitivity, with errors mostly under 4.72%.
Mo, 24.3.2025
LabRulez
Article | Webinars
Nitrosamines and Impurities Resource Hub
Over four years ago, the nitrosamine crisis shook the pharmaceutical world, and it still remains a hot topic. Since then, more stringent regulations have been put in place.
Th, 20.3.2025
Waters Corporation (Europe)
Article | Video
Data Processing Using Thermo Freestyle Software with NIST MSMS Search for Compound Identifications (“Nearby Precursors” Enhancement)
Part 1A discusses the using the "Nearby Precursor" to easily display a MSMS spectrum associated with an ion in MS.
Th, 20.3.2025
James Little/Mass Spec Interpretation Services
Article | Science and research
People understand that air pollution needs to be addressed, but they often don’t realize that the problem affects them as well
Ondřej Mikeš works at the RECETOX center as an environmental epidemiologist in the Human Exposure and Risk Assessment group, focusing on external exposures in epidemiological research.
Th, 20.3.2025
RECETOX - Centrum pro výzkum toxických látek v prostředí
Article | Science and research
RECETOX Research Team Successfully Completes Project on Male Reproductive Toxicity Assessment Without Animal Testing
The RECETOX center successfully completed a project funded by GAČR - Alternative Approaches in the Assessment of Male Reproductive Toxicity of Chemical Mixtures Without Animal Testing.
We, 19.3.2025
RECETOX - Centrum pro výzkum toxických látek v prostředí
Presentation | Video
Online SEC-UV-RP-MS for characterization of adeno-associated viruses (Megane Aebischer, MDCW 2025)
This study introduces a 2D-LC-MS method for AAV characterization, integrating SEC and RP-LC-MS to analyze HMWs, viral proteins, and PTMs, improving gene therapy vector assessment.
We, 19.3.2025
The Multidimensional Chromatography Workshop
Article | Application
News from LabRulezLCMS Library - Week 12, 2025
This week we bring you application notes by Agilent Technologies, Knauer, Shimadzu and Waters Corporation and technical notes by ALS Europe and Thermo Fisher Scientific!
We, 19.3.2025
LabRulez
Article | Product
Automating the processing of analytical data for System Suitability Testing (Case study)
This case study examines how AstraZeneca integrated Chrom SST automation into their purification workflow, enabling daily checks, long-term trend analysis, and preventive maintenance.