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Quality-by-Design-Driven RP-HPLC Method Development and Validation for Impurity Analysis of Elexacaftor, a Cystic Fibrosis Drug, with LC-MS/MS-Based Degradant Identification
Scientific article | Science and research

Quality-by-Design-Driven RP-HPLC Method Development and Validation for Impurity Analysis of Elexacaftor, a Cystic Fibrosis Drug, with LC-MS/MS-Based Degradant Identification

A validated QbD-based RP-HPLC method enables robust, stability-indicating impurity analysis of Elexacaftor, supporting process development and quality control in drug manufacturing.
Mo, 22.12.2025
LabRulez
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Quality-by-Design-Driven RP-HPLC Method Development and Validation for Impurity Analysis of Elexacaftor, a Cystic Fibrosis Drug, with LC-MS/MS-Based Degradant Identification
Natural Product Discovery through Liquid Extraction Based Ambient ionization Mass Spectrometry
Interview | Video

Natural Product Discovery through Liquid Extraction Based Ambient ionization Mass Spectrometry

Interview with PhD researcher Jess on using ambient ionization mass spectrometry to screen and prioritize novel metabolites, reduce solvent use, and streamline natural product discovery before chromatography.
Fr, 19.12.2025
Organomation
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Natural Product Discovery through Liquid Extraction Based Ambient ionization Mass Spectrometry
The butterfly – a symbol of hope for oncology patients – chosen as the emblem of Taveren Therapeutics, a new biotech company emerging from IOCB Prague
Article | Science and research

The butterfly – a symbol of hope for oncology patients – chosen as the emblem of Taveren Therapeutics, a new biotech company emerging from IOCB Prague

IOCB Prague is co-founding Taveren Therapeutics, a new biotech spin-off developing a novel cancer treatment strategy based on reactivating the body’s natural tumor suppressors.
Fr, 19.12.2025
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
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The butterfly – a symbol of hope for oncology patients – chosen as the emblem of Taveren Therapeutics, a new biotech company emerging from IOCB Prague
PF 2026 Watrex Prague
Article | Various

PF 2026 Watrex Prague

A heartfelt thank you to our customers and partners for their trust and cooperation, with warm wishes for a joyful Christmas and a successful, stable, and innovative year 2026.
Th, 18.12.2025
Watrex Praha
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PF 2026 Watrex Prague
 Revolution in water purification: Membrane removes dangerous bacteria and heavy metals
Article | Science and research

Revolution in water purification: Membrane removes dangerous bacteria and heavy metals

Scientists from CATRIN and CEET developed a filtration membrane that removes bacteria and toxic heavy metals from water in one step, without energy or chemicals.
Th, 18.12.2025
CATRIN
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 Revolution in water purification: Membrane removes dangerous bacteria and heavy metals
News from LabRulezLCMS Library - Week 51, 2025
Article | Application

News from LabRulezLCMS Library - Week 51, 2025

This week we bring you application notes by Agilent Technologies, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!
We, 17.12.2025
LabRulez
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News from LabRulezLCMS Library - Week 51, 2025
Sample Prep for N-linked Glycans
Article | Academy

Sample Prep for N-linked Glycans

A streamlined workflow for N-linked glycan sample preparation, combining PNGase F digestion, fluorescent labeling, and HILIC SPE clean-up for reliable HPLC and LC-MS analysis.
We, 17.12.2025
Phenomenex
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Sample Prep for N-linked Glycans
Automated Device Shutdown After Sequence Completion in Clarity Chromatography Software
Article | Product

Automated Device Shutdown After Sequence Completion in Clarity Chromatography Software

Learn how shutdown methods in Clarity Sequence Options enable automatic post-sequence actions such as cooling devices, switching off lamps, or sending shutdown commands after the last run.
Tu, 16.12.2025
DataApex
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Automated Device Shutdown After Sequence Completion in Clarity Chromatography Software
Beyond Blood: Sheffield Teaching Hospitals NHS Foundation Trust Develops HRAM-Powered Method for Post-Mortem Toxicology Analysis
Article | Science and research

Beyond Blood: Sheffield Teaching Hospitals NHS Foundation Trust Develops HRAM-Powered Method for Post-Mortem Toxicology Analysis

Sheffield researchers validated Thermo Scientific Tox Explorer for LC-MS/MS drug screening in post-mortem vitreous humor, confirming its sensitivity, stability and forensic value.
Tu, 16.12.2025
Thermo Fisher Scientific
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Beyond Blood: Sheffield Teaching Hospitals NHS Foundation Trust Develops HRAM-Powered Method for Post-Mortem Toxicology Analysis
Exploring Domestic Discharge Patterns in Wastewater through LC-HRMS Screening and Temporal Clustering
Scientific article | Science and research

Exploring Domestic Discharge Patterns in Wastewater through LC-HRMS Screening and Temporal Clustering

LC-HRMS screening combined with temporal clustering identified daily domestic discharge patterns in wastewater, enabling improved interpretation of population chemical exposure.
Mo, 15.12.2025
LabRulez
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Exploring Domestic Discharge Patterns in Wastewater through LC-HRMS Screening and Temporal Clustering
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LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike