<p><strong>In the week from March 22, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>700 LC and GC webinars</strong>.</p>
<h5><strong>1. Dr. Maisch: MODCOL Preparative Scale SPRING COLUMN Hardware and MULTIPACKER</strong></h5>
<p>In this webinar you will learn more about our dependable MODCOL preparative SPRING COLUMN hardware and our latest upgrades on available dimensions and MULTIPACKER.</p>
<h5><strong>2. Waters Corporation: Waters LC Symposium - Plenary and Pharma</strong></h5>
<p>Waters Corporation is pleased to bring together chromatography thought leaders for a week of scientific talks, demonstrations, discussions, and networking regarding novel LC technologies and applications.</p>
<h5><strong>3. PerkinElmer: Mycotoxins Webinars Series: Portfolio</strong></h5>
<p>Learn about the mycotoxin analytical solutions which will help you in your daily tasks to ensure food safety, comply with regulations, reduce time to results and improve efficiency. </p>
<h5><strong>4. Waters Corporation: Waters LC Symposium - Pharma</strong></h5>
<h5><strong>5. Phenomenex: Getting Low With Sample Preparation: How to Achieve Less Background Interference and Lower Limits of Detection</strong></h5>
<p>This webinar will focus on how to develop an easy sample preparation method using solid supported liquid extraction (SLE) to achieve a fast clean-up solution from biological matrices.</p>
<h5><strong>6. Agilent Technologies: Exploring Agilent Software for Machine Learning and Classification with High Resolution Liquid Chromatography Mass Spectrometry Data and Experimental Design Ideas to Maximize Success</strong></h5>
<p>Here we will explore different application spaces for HR-LCMS in food, environment and the life sciences with MassHunter Classifier software that can directly read raw data and make predictions.</p>
<h5><strong>7. SelectScience/Thermo Scientific: Robust metabolic profiling for routine quantitation and confident unknown identification</strong></h5>
<p>In this webinar, we present a targeted profiling workflow for the nutrient evaluation of bovine serum samples as supplements in cell culture by Orbitrap Exploris 120 mass spectrometer.</p>
<h5><strong>8. Waters Corporation: Applications of Ion Mobility-Mass Spectrometry in Lipid Profiling and Imaging</strong></h5>
<p>In recent years, liquid chromatography coupled to ion mobility-mass spectrometry (LC-IM-MS) for lipidomics has shown advantages in lipid identification.</p>
<h5><strong>9.  Waters Corporation: Waters LC Symposium - Pharma and Food</strong></h5>
<h5><strong>10. Agilent Technologies: GPC Analysis with Fraction collection using OpenLAB CDS: A practical approach to simplify further characterization of complex mixtures</strong></h5>
<p>This webinar will present a complete solution for an Agilent 1260 Infinity II GPC system coupled to a Fraction Collector controlled by Open LAB CDS software with integrated GPC workflows.</p>
<h5><strong>11. Phenomenex/SCIEX: Danaher Life Sciences eSeminar - Latest Trends in Precision Medicine</strong></h5>
<p>This eSeminar, “Latest Trends in Precision Medicine,” will bring together Beckman, Leica, Phenomenex, Pall, Integrated DNA and SCIEX to share the latest innovations and tools.</p>
<h5><strong>12. Waters Corporation: Oxyanions in the water – a tale of 4 analytes in 5 minutes</strong></h5>
<p>The purpose of our work is to demonstrate a direct injection LC-MS/MS method for the determination of Oxyanions in drinking water.</p>
<h5><strong>13. VWR/Avantor: How to double your sample capacity in less time with an existing autosampler!</strong></h5>
<p>Join us to review sample handling efficiencies for LC and GC autosamplers that you can implement into your workflow.</p>
<h5><strong>14. SGS: Chemical Characterization of Medical Device Materials According to ISO 10993-18:2020</strong></h5>
<p>This presentation will focus on the analytical considerations of medical device extractable and leachable (E&amp;L) studies as per the new ISO 10993-18 chapter.</p>
<h5><strong>15. Evosep Biosystems: Rapid, robust and reproducible Host Cell Protein analysis with Evosep One</strong></h5>
<p>In this webinar we will explore the possibilities of using the Evosep One technology to perform rapid, robust and reproducible HCP analysis. </p>
<h5><strong>16. Technology Networks/Victus Capital Ventures: Uncovering the Lineage of Extraction and the Future of the Craft</strong></h5>
<p>During this webinar we will discuss the history of extraction, the most common methodologies of extraction and the technical developments of each and the future of cannabis extraction and innovations.</p>
<h5><strong>17. Waters Corporation: Waters LC Symposium - Materials and Pharma</strong></h5>
<h5><strong>18. Agilent Technologies: How Can Automation Help Advance my Infectious Disease Research?</strong></h5>
<p>Learn how automation can help advance your infectious disease research.</p>
<h5><strong>19. Waters Corporation: Waters LC Symposium - Biomedical Research</strong></h5>


LC and LCMS webinars - Week 12

<p><strong>MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release.</strong> </p>
<p>I will attempt to introduce the user to the use of the <strong>NIST Version 2.4 search software</strong> employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the <strong>identification of unknowns</strong>.</p>
<p>NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. </p>
<p>See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a></p>
<p>This involves a very comprehensive process for <strong>selecting</strong> pertinent compounds for purchase and subsequent <strong>analyses</strong>. The problem with variability of the spectra is reduced by analyzing the samples on a <strong>variety of instruments</strong> at a <strong>variety of energy levels</strong> (20 steps). In addition, many different <strong>precursor ions</strong> and <strong>fragment ions</strong> are characterized (MSⁿ). This has already led to a very large high quality library of <strong>accurate mass MS/MS spectra in the 2020 release version</strong> (31K compounds/1.3 M spectra) and the effort is ongoing.</p>
<h3><strong>The Part V will cover:</strong></h3>
<p>Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.</p>
<ul>
<li>Introduction of Presenter, James Little </li>
<li>Table of Contents</li>
<li>Series Topics</li>
</ul>
<p>-Help Files for NIST Search </p>
<ul>
<li>NIST Software in General is “Windows Compliant”</li>
<li>Session Topics and Choice of Drawing Program</li>
<li>Critical Settings for Similar Structure Searches</li>
<li>Critical Settings for Exact Structure Searches </li>
<li>Critical Settings Turn Off Any Filtering Options Initially</li>
<li>Obtaining Structure from Drawing Program </li>
<li>Pasting Structure into NIST Search </li>
<li>Search for Similar Structures after Inserting Clipboard Structure </li>
<li>Search for Exact Structures </li>
<li>Tips for Displaying Similar and Exact Search Result with DeltaMass </li>
<li>Reverse Process: Sending Structures from NIST to Drawing Program </li>
<li>Using Compare Window to Display Multiple Spectra </li>
<li>Sending Structures Directly to Drawing Program</li>
<li>Live Demo YouTube Presentation</li>
<li>Presentation References (Internet Links)</li>
<li>Acknowledgements</li>
</ul>
<h3><strong>Future parts will focus on:</strong></h3>
<ul>
<li>Part VI:   <strong>MS Interpreter Correlation of Substructure to MSMS Ions</strong></li>
<li>Part VII:  <strong>Using and Creating Other MSMS Libraries</strong></li>
<li>Part VIII: <strong>Identification of Unknowns with “Spectraless” Libraries</strong></li>
</ul>
<h3><strong>The past sections have focused on:</strong></h3>
<ul>
<li><p><a href="https://lcms.labrulez.com/article/1068"><strong>Part I: Overview of Software and User-Customized Configurations</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1088"><strong>Part II: NIST Search Software and Libraries</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1110"><strong>Part III: More Detailed Discussion of MSMS Hybrid Search</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1130"><strong>Part IV: Importing MSMS Spectra</strong></a></p>
</li>
</ul>


LC/MS Unknown Identifications Using MSMS Libraries Part V: NIST Structure Searches

<p><strong>In the week from March 29, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>700 LC and GC webinars</strong>.</p>
<h5><strong>1. Waters Corporation: Increasing Efficiency in a Remote Environment</strong></h5>
<p>In this webinar we’ll discuss how laboratory automation can help address some of new challenges due to pandemic situation and enhance COVID-19 research.</p>
<h5><strong>2. C&amp;EN/Bruker Daltonics: MALDI Tandem Mass Spectrometry – the Most Versatile Analytical Tool for Analysis of Polymeric Materials</strong></h5>
<p>Advantages of MALDI/MS/MS will be demonstrated with the precise structural analysis of a wide variety of synthetic materials, including large and crosslinked polymers, additives and synthetic polymer surfaces.</p>
<h5><strong>3. VWR: Back To Basics: Fundamental Concepts of HPLC &amp; UHPLC</strong></h5>
<p>The basis of the separation process and retention mechanisms will be covered, as well as how the important parameters of resolution, peak shape and efficiency are measured.</p>
<h5><strong>4. Agilent Technologies: Characterization of MassTech AP MALDI Source with Agilent 6545 QTOF and 6560 IM-QTOF for MS Imaging</strong></h5>
<p>The AP MALDI source developed by MassTech Inc was hyphenated to Agilent 6545, a high-resolution mass spectrometer. AP MALDI MS imaging was demonstrated using tissue-simulating peptide spots.</p>
<h5><strong>5. Phenomenex: Understanding Ion-Exchange Selectivity In Biomolecules Analysis</strong></h5>
<p>In this webinar we will cover: Ion Exchange Chromatography, PTMs &amp; Charge Heterogeneity, bioZen WCX, Effects of pH &amp; Common Buffers, Salts VS pH Gradient, Method Optimization, etc...</p>
<h5><strong>6. SelectScience/Agilent Technologies: Comprehensive pesticide testing required to ensure safe cannabis and cannabinoid products</strong></h5>
<p>In this SelectScience webinar, learn analytical methodologies for comprehensive targeted and semi-targeted pesticide analysis to better ensure the safety of cannabis products, where legalized.</p>
<h5><strong>7. Waters Corporation: A Focus on PCR Diagnostic Probes: Oligonucleotide LC Analysis and Purification</strong></h5>
<p>We’ll discuss strategies for lab scale and semi-preparative purification of diagnostic probes through illustrated examples. In addition, we’ll review PREMIER solutions.</p>
<h5><strong>8. Technology Networks/SCIEX: Digital Freezing of Metabolomics Samples</strong></h5>
<p>This webinar showcases the use of SWATH® Acquisition on the benchtop X500R QTOF System for digital freezing of metabolomics samples.</p>
<h5><strong>9. Agilent Technologies: WHY Did That Happen?</strong></h5>
<p>In this webinar we will discuss some common problems, how to identify their source, and how to fix them.</p>
<h5><strong>10. Agilent Technologies: Analysis of Water-Soluble B Vitamins by the Ultivo LC-MS TQ</strong></h5>
<p>In this webinar we will present analysis of Water-Soluble B Vitamins by the Agilent Ultivo LC-MS TQ (triple quadrupole liquid chromatography/mass spectrometry system).</p>
<h5><strong>11. Agilent Technologies: Agilent RapidFire 400: A Complete Approach To High-Throughput Mass Spectrometry</strong></h5>
<p>Explore some of the applications being accelerated using RapidFire and learn how it can enhance your laboratory’s capabilities.</p>


LC and LCMS webinars - Week 13

<p><strong>In the week from April 5, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>700 LC and GC webinars</strong>.</p>
<h5><strong>1. Agilent Technologies: Advanced Algorithms for the Discovery of Related Components and Application to PFAS and Fentanyl Research</strong></h5>
<p>The MassHunter acquisition concept of a Preferred MSMS list will be presented together with concept of Mass Defect, MSMS pseudo Constant Neutral Loss, and MSMS Reporter Ions.</p>
<h5><strong>2. Technology Networks/SCIEX: Accelerating AAV-Based Gene Therapy Development with MS</strong></h5>
<p>Using MS data to improve characterization of AAV from different sources will help scientists to make informed decisions in the development of cost-effective, safe and potent gene therapeutics.</p>
<h5><strong>3. Technology Networks/Bruker: Flow Injection Analysis-Magnetic Resonance Mass Spectrometry for High-Throughput Metabolomics</strong></h5>
<p>This webinar will introduce the FIA-MRMS workflow and present two case studies where it is used.</p>
<h5><strong>4. The Analytical Scientist/PIC Solution: Advances in Eco-Sustainable CO2 Technologies</strong></h5>
<p>The Forum provides a unique opportunity to discuss advances in next-generation of eco-sustainable CO2 Separation (SFC) and Extraction (SFE) technologies.</p>
<h5><strong>5. Agilent Technologies: Mass Spectrometry for the Masses, Open Access LC and LC/MS Using Agilent WalkUp</strong></h5>
<p>We will provide an introduction to WalkUp briefly discussing the user experience from the administrator (setting up groups, users, methods, data analysis confirmation) and users’ (running samples) perspectives.</p>
<h5><strong>6. Waters Corporation: Nitrosamines Analysis (Step 2): Confirmatory testing</strong></h5>
<p>In this webinar, we will going through the latest regulatory requirements for testing nitrosamines in solvents, drug substance and drug products.</p>
<h5><strong>7. Shimadzu Scientific Instruments: Subsurface Microbiology: Metabolism by HPLC</strong></h5>
<p>In this work, we discovered a novel strict anaerobic thermophilic bacterium from a monitoring borehole at a depth of 691 meters below land surface.</p>
<h5><strong>8. Agilent Technologies: VWorks version 14.0: Enhanced Features of Compliance</strong></h5>
<p>Join us and learn about how the new VWorks comes in two different editions to suit your laboratory’s specific regulatory needs.</p>


LC and LCMS webinars - Week 14

<p><strong>In the week from April 12, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>700 LC and GC webinars</strong>.</p>
<h5><strong>1. PerkinElmer: Food Safety: Determination of Mycotoxins in food by LC-MS/MS</strong></h5>
<p>This webinar will present insights into risk assessment with a focus on the LC-MS/MS methods, along with solutions for performing selective, sensitive and compliant analysis. </p>
<h5><strong>2. Thermo Fisher Scientific: Charged Aerosol Detection Symposium - Session 1</strong></h5>
<p>Join our interactive and live charged aerosol detection symposium with tips, tricks, pointers and expert advice from our guest speakers! </p>
<h5><strong>3. Phenomenex: Strategies, Tips and Tricks for Simplified Chiral Method Development</strong></h5>
<p>In this presentation, we will explore the factors that contributes to successful chiral separation.</p>
<h5><strong>4. Agilent Technologies: A Comprehensive Approach to Targeted and Untargeted Screening Methodology for Emerging Synthetic Fentanyl Analogues using High Resolution Accurate Mass Spectrometry</strong></h5>
<p>Herein, a targeted and untargeted screening workflow by LC/MS/MS using Agilent’s 6546 QTOF will be presented for approximately 150 fentanyl analogues.</p>
<h5><strong>5. Thermo Fisher Scientific: Charged Aerosol Detection Symposium - Session 2</strong></h5>
<p>Learn how CAD can be applied in your work with tips, tricks, pointers, and expert advice from our guest speakers.</p>
<h5><strong>6. Waters Corporation: Benefits of IMS to MetID and Structural Elucidation</strong></h5>
<p>Our two guest speakers Dr. Ralf Laux and Dr. Ian Wilson bring decades of experience in Drug Metabolism and Pharmacokinetics.</p>
<h5><strong>7. LCTech: FREESTYLE XANA - The Specialist for your Water Samples</strong></h5>
<p>Learn more about FREESTYLE XANA robotic system for automatic SPE sample preparation for analysis of large volumes of water samples.</p>
<h5><strong>8. Waters Corporation: Solving Large Molecule Questions with Accessible LC/MS in Academia</strong></h5>
<p>Join Christian Winter, UNI of Frankfurt, and Dr John Walsby-Tickle, UNI of Oxford, online to learn how an easy-to-use routine LC/MS brings academics in life sciences closer to the point of decision.</p>
<h5><strong>9. Thermo Fisher Scientific: Charged Aerosol Detection Symposium - Session 3</strong></h5>
<p>Learn more from our speakers in these industries sharing tips and tricks, with pointers, and expert advice. </p>
<h5><strong>10. Bruker Daltonics: Bead Assisted Mass Spectrometry assay platform for targeted proteomics</strong></h5>
<p>The webinar will focus on the detailed description of the workflow and case studies of BAMS™ assays developed for targets relevant to neurology and virology.</p>
<h5><strong>11. SelectScience/Merck: BioSPME: A new tool for drug-protein binding determination</strong></h5>
<p>In this webinar, Dr. Olga Shimelis will present the use of new product – Supel™ BioSPME C18 96-Pin Devices – for in vitro measurement of protein binding properties of pharmaceutical compounds in plasma. </p>
<h5><strong>12. Thermo Fisher Scientific: The Delights of Diversity: A Multitude of Separation Techniques Combined with Mass Spectrometry for Characterization in Biopharmaceutical Development</strong></h5>
<p>Here the impact of hyphenating a broad range of separation techniques to high resolution accurate mass (HRAM) mass spectrometry (MS) will be discussed through case studies.</p>
<h5><strong>13. Agilent Technologies: WHO Do I Turn To? Chromatography Resources</strong></h5>
<p>Looking for answers to your chromatography questions? Who do you turn to? This webinar will look at available resources to help meet your chromatography needs.</p>
<h5><strong>14. SelectScience/Waters Corporation/Andrew Alliance: Virtual Event: Leveraging automation technologies to work smarter</strong></h5>
<p>This virtual event brings you three webinars from experts in the field of automation who will discuss how you can work smarter.</p>


LC and LCMS webinars - Week 15

<p><strong>In the week from April 19, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>800 LC and GC webinars</strong>.</p>
<h5><strong>1. Dr. Maisch High Performance LC GmbH: Chiral HPLC: From Basics to the Latest and Unique Novelties</strong></h5>
<p>We invite you to join our free webinar to understand the principles of chiral HPLC, different types of stationary phases and their characteristics and separation modes.</p>
<h5><strong>2. Separation Science/Thermo Fisher Scientific: The Challenges of Pesticide Analysis - LC or GC Triple Quadrupole?</strong></h5>
<p>This webinar takes a look at the pros and cons of LC-QqQ and GC-QqQ for the analysis of pesticides in food and agricultural matrices. Industry and technology experts will provide their insights.</p>
<h5><strong>3. C&amp;EN/Wyatt Technology: Quality attributes and extended characterization of lentiviral and gammaretroviral vectors using light scattering</strong></h5>
<p>We will demonstrate batch dynamic light scattering (DLS) for rapid, low-resolution measurements and MALS in combination with field-flow fractionation (FFF) for extended characterization of viral vectors.</p>
<h5><strong>4. Thermo Fisher Scientific: BioPharma Finder software for characterization of protein and oligonucleotide based biotherapeutics</strong></h5>
<p>BioPharma Finder software is a workflow driven solution for complete characterization of biotherapeutics.</p>
<h5><strong>5. Agilent Technologies: Method Development &amp; Optimization Workshop</strong></h5>
<p>In this online workshop, Agilent presents the common challenges faced these days and focuses on Method Development Solutions with maximum efficiency to optimize your workflows.</p>
<h5><strong>6. Phenomenex: LC Method Development and Problem Prevention for Pharmaceutical Methods</strong></h5>
<p>This webinar will cover topics like LC Column Selection and Method Development and Overview of USP Allowable Adjustments and Avoid LC Problems through Proper Column Care and Troubleshooting.</p>
<h5><strong>7. Waters Corporation: Meet the Experts - Part 1 - Alternative Procurement Strategies</strong></h5>
<p>Richard Styles details the alternative buying options available to you in today&#39;s market. </p>
<h5><strong>8. Wiley Analytical Science/Merck: Lipidomics from Structure to Function</strong></h5>
<p>Part I: Lipidomics from Structure to Function</p>
<h5><strong>9. Wiley Analytical Science/Merck: Quantitative Bottom-Up Shotgun Lipidomics Using High-Resolution Orbitrap FTMS</strong></h5>
<p>Part II: Quantitative Bottom-Up Shotgun Lipidomics Using High-Resolution Orbitrap FTMS</p>
<h5><strong>10. Thermo Fisher Scientific: GlycanExplorer – A software solution for high throughput bio-therapeutic glycan characterization</strong></h5>
<p>In this presentation, we will discuss how the software detects the peaks from your raw data, identify the probable glycans with the help of different search workflows, and present the results.</p>
<h5><strong>11. Petro Industry News/Waters Corporation: High Resolution MS and Statistical Analysis Approaches to Lubricant Formulation Research and Development</strong></h5>
<p>We will outline a simple and efficient workflow that uses HRMS and statistical analysis of the acquired data to understand the differences between several automotive lubricant oils at a molecular level.</p>
<h5><strong>12. Waters Corporation: MaxPeak HPS Innovation to reduce analyte/surface interactions</strong></h5>
<p>This 1st session will introduce you to MaxPeak High Performance Surface (HPS) technology, the integral part of our ACQUITY PREMIER Solution to reduce analyte/surface interactions.</p>
<h5><strong>13. Wiley Analytical Science/YMC Europe:Characterisation and Quantification of Biomolecules</strong></h5>
<p>The first part of the talk will provide a brief introduction to bioanalytics in general, as well as to the quantification and characterization of intact proteins.</p>
<h5><strong>14. Wiley Analytical Science/YMC Europe: Analysing Antibodies by Different LC Separation Modes</strong></h5>
<p>The second part is dedicated to peptide analysis and covers classical and multidimensional chromatography as well as automated sample preparation using enzyme reactors.</p>
<h5><strong>15. Thermo Fisher Scientific: Increasing proteoform level insight with quantitative Top-Down proteomics using Proteome Discoverer 2.5 software</strong></h5>
<p>This presentation will provide and overview of Top-Down proteomics from sample prep to generating results. Topics will be presented in practical terms with relevant background information. </p>
<h5><strong>16. Agilent Technologies: Cannabis Safety - Trace Analysis of Pesticides &amp; Mycotoxins via LC/QQQ in Cannabis Flower and Concentrates</strong></h5>
<p>This presentation will detail an LC/MS/MS analytical workflow developed by Agilent for the accurate measurement of combined pesticide and mycotoxin action lists according to the requirements of U.S.</p>


LC and LCMS webinars - Week 16

<p><strong>MS/MS (Tandem) spectra can be used to identify unknowns employing library searches. This is accomplished in much the same approach as that employed for EI GC-MS with the NIST search software. The much improved NIST Search Version 2.4 is included with the 2020 library release.</strong> </p>
<p>I will attempt to introduce the user to the use of the <strong>NIST Version 2.4 search software</strong> employing NIST, Wiley, “crowd-sourced (MoNA)”, and user libraries for the <strong>identification of unknowns</strong>.</p>
<p>NIST has an ambitious program to extend their already comprehensive, high-quality MS/MS databases. </p>
<p>See the following link: <a href="https://littlemsandsailing.files.wordpress.com/2020/12/xiaoyu_yang_asms2020_presentation.pdf">NIST Pipeline for Extending MS/MS Libraries</a></p>
<p>This involves a very comprehensive process for <strong>selecting</strong> pertinent compounds for purchase and subsequent <strong>analyses</strong>. The problem with variability of the spectra is reduced by analyzing the samples on a <strong>variety of instruments</strong> at a <strong>variety of energy levels</strong> (20 steps). In addition, many different <strong>precursor ions</strong> and <strong>fragment ions</strong> are characterized (MSⁿ). This has already led to a very large high quality library of <strong>accurate mass MS/MS spectra in the 2020 release version</strong> (31K compounds/1.3 M spectra) and the effort is ongoing.</p>
<h3><strong>The Part VI will cover:</strong></h3>
<p>Detailed Handouts including tables of content are available in the <a href="https://lcms.labrulez.com/library?search=lc%2Fms%20unknown%20identifications%20using%20msms%20libraries&amp;manufacturerItems=55">LabRulezLCMS library</a>.</p>
<ul>
<li>Introduction of Presenter, James Little</li>
<li>Table of Contents</li>
<li>Series Topics</li>
<li>Help Files for NIST Search </li>
<li>NIST Software in General is “Windows Compliant” </li>
<li>Session Topics </li>
<li>Adding a Structure to a Spectrum</li>
<li>Sending Spectrum with Structure to MS Interpereter </li>
<li>Processing Data in MS Interpreter </li>
<li>Suggested Default Settings</li>
<li>Displaying the Propose Substructures Correlated to Ions </li>
<li>Stepping through More Than One Proposed Structure </li>
<li>Lassoing Structures Manually </li>
<li>Processing Any Entry in NIST Search with structure/spectrum</li>
<li>Direct Structure Paste in MS Interpreter </li>
<li>Processing MS/MS Spectra Containing Isotopic Clusters</li>
<li>Live YouTube Demonstration</li>
<li>References with Internet Links</li>
<li>Acknowledgements</li>
</ul>
<h3><strong>Future parts will focus on:</strong></h3>
<ul>
<li>Part VII:  <strong>Using and Creating Other MSMS Libraries</strong></li>
<li>Part VIII: <strong>Identification of Unknowns with “Spectraless” Libraries</strong></li>
</ul>
<h3><strong>The past sections have focused on:</strong></h3>
<ul>
<li><p><a href="https://lcms.labrulez.com/article/1068"><strong>Part I: Overview of Software and User-Customized Configurations</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1088"><strong>Part II: NIST Search Software and Libraries</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1110"><strong>Part III: More Detailed Discussion of MSMS Hybrid Search</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1130"><strong>Part IV: Importing MSMS Spectra</strong></a></p>
</li>
<li><p><a href="https://lcms.labrulez.com/article/1162"><strong>Part V: NIST Structure Searches</strong></a></p>
</li>
</ul>


LC/MS Unknown Identifications Using MSMS Libraries Part VI: MS Interpreter Correlation of Substructure to MSMS Ions

<p><strong>In the week from April 26, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>900 LC and GC webinars</strong>.</p>
<h5><strong>1. Agilent Technologies: MassHunter WalkUp: Making the Complex Simple, Part 1</strong></h5>
<p>This webinar explores what MassHunter WalkUp can do for your lab, highlights experience from administrator and users’ perspectives for various workflows, and demonstrates ease-of-use.</p>
<h5><strong>2. Thermo Fisher Scientific: Advancing carbohydrate analysis - Glycans</strong></h5>
<p>This webinar will talks about filling the gaps in glycan analysis with advanced ion chromatography column technology.</p>
<h5><strong>3. Waters Corporation: Is your system truly inert? - A PREMIER experience</strong></h5>
<p>Details on the development and application of PREMIER Standards to support the characterization of metal interactions to ensure performance and guide troubleshooting efforts will be discussed.</p>
<h5><strong>4. C&amp;EN/Advanced Materials Technology: Reversed phase liquid chromatography: fundamentals and strategies for faster method development</strong></h5>
<p>In this webinar we address the fundamental concepts that are key to developing optimized methods via Reversed Phase Liquid Chromatography (RPLC) (the most adopted and common mode of separation science).</p>
<h5><strong>5. Thermo Fisher Scientific: In-depth protein characterization with BioPharma Finder software – intact mass analysis, peptide mapping and new host cell protein workflow</strong></h5>
<p>Learn how to use in-depth protein characterization tools and how to analyze Host cell proteins in your biotherapeutic protein sample. </p>
<h5><strong>6. Phenomenex: Proper Method Scaling to Achieve Your UHPLC and HPLC Goals</strong></h5>
<p>This presentation aims to provide a framework within which to navigate the HPLC/UHPLC method scaling parameters to accomplish the goals of an analysis.</p>
<h5><strong>7. Agilent Technologies: Sensitive Techniques for Targeted PFAS Analysis in Water</strong></h5>
<p>W tomto webináři prozkoumáme použití nejnovější technologie QQQ 6495C a její schopnost tlačit citlivost na nižší hodnoty u složitějších PFAS, jako je GenX a zaměříme sea citlivost a vysokou propustnost vzorků.</p>
<h5><strong>8. Agilent Technologies: Using OpenLab to Enhance the Empower Experience</strong></h5>
<p>We will highlight how to manage Empower data in Technology Neutral formats such as AniML and Allotrope enabling long term record retention, data exchange, and cross platform reporting of multivendor data.</p>
<h5><strong>9. LECO: LECO MOSH/MOAH Workshop - Fundamentals On Comprehensive MOSH/MOAH Analysis – Day 1</strong></h5>
<p>Day one features Fundamentals on LC-GC Coupling and Principles and Instrumentation of GC×GC and ToF-MS.</p>
<h5><strong>10. Agilent Technologies: Virtual Ion Mobility Spectrometry (IMS) Mini-Symposium</strong></h5>
<p>The event consists of six short scientific IMS (Ion Mobility Spectrometry) presentations delivered by guest international speakers and Agilent R&amp;D scientists.</p>
<h5><strong>11. Wiley Analytical Science/Bruker: Highly Multiplexed Targeted Proteomics Acquisition on a TIMS-QTOF</strong></h5>
<p>The method&#39;s applicability is demonstrated by measuring Kras, Nras, and Hras in biological samples and the most common cancer-associated Kras mutations.</p>
<h5><strong>12. Waters Corporation: Benefits of the Cyclic IMS for HDX/MS Experiments</strong></h5>
<p>Hear from Mark Skehel on the use of Cyclic IMS to investigate the conformations of bovine mitochondrial complex I. </p>
<h5><strong>13. Wiley Analytical Science/Bruker: Leveraging prm-PASEF on the timsTOF Pro to Interrogate the Functional Proteome</strong></h5>
<p>Here we describe PASEF-PRM-LIVE, a framework implementing on-the-fly adjustment of the detection window to maximize target coverage. </p>
<h5><strong>14. Thermo Fisher Scientific: Automated online µSPE cartridge clean-up of QuEChERS extracts before LC-MS/MS and GC-MS/MS analysis of pesticides in foods.</strong></h5>
<p>We will highlight an automated online miniaturized cartridge clean-up approach providing more effective clean-up of QuEChERS extracts to overcome the analytical challenges in pesticide residue analysis.</p>
<h5><strong>15. Technology Networks/Bruker: MALDI Imaging – A Powerful Tool in Pathology</strong></h5>
<p>In this webinar, Kristina Schwamborn, will discuss how MALDI-IMS can overcome the limitations of other approaches in the discovery and identification of new classifying marker molecules and profiles.</p>
<h5><strong>16. Thermo Fisher Scientific: Getting the most out of Thermo Scientific&#39;s latest acquisition technologies FAIMS and SureQuant with Biognosys&#39; software solutions Spectronaut and SpectroDive</strong></h5>
<p>Two speakers from Biognosys, Next gen. proteomics solutions - will talk about the analysis of FAIMS-DIA data using Spectronaut software, and SureQuant targeted quantitation workflow using SpectroDive software.</p>
<h5><strong>17. Agilent Technologies: Resolve More Isoforms with the New Agilent 1290 Infinity II Bio LC System</strong></h5>
<p>Join Agilent Technologies LC Applications Scientist, for an in depth look Agilent Technologies’ new 1290 Infinity II Bio LC systems and decide the optimal pumping system for your application needs.</p>
<h5><strong>18. Thermo Fisher Scientific: Advancing carbohydrate analysis - Eluent generation</strong></h5>
<p>This webinar will talks about simplify the complexity of carbohydrate analysis with eluent generation.</p>
<h5><strong>19. Waters Corporation: LC-MS/MS multi-residue method: Routine analysis and workflow efficiency</strong></h5>
<p>The first episode of Pesticide Thursdays is dedicated to the Multiresidue Method for Quantification of Pesticides in Food by UPLC-MS/MS – SANTE guidelines, MQLs, and tools to modernize workflow efficiency.</p>
<h5><strong>20. LECO: LECO MOSH/MOAH Workshop - Fundamentals On Comprehensive MOSH/MOAH Analysis – Day 2</strong></h5>
<p>Day two features LC-GC×GC–ToF-MS/FID: A Powerful Platform for MOSH&amp;MOAH Determination.</p>
<h5><strong>21. VWR: Mini-symposium: Method development strategies and devising solutions for nitrosamine analysis</strong></h5>
<p>This webinar will cover: A Systematic UHPLC/HPLC Method Development Strategy with Complementary Stationary Phases to Maximise Selectivity and Resolution; Analysis of nitrosamines in APIs.</p>
<h5><strong>22. Waters Corporation: Comprehending COVID-19: The Application of a Mixed-Mode Stationary Phase for the Analysis of Small Molecule Drugs Evaluated for the Treatment of SARS-CoV-2 Infections</strong></h5>
<p>Join us for our upcoming COVID Spotlight webinar to learn about using Mixed-Mode Chromatography for small molecule drug analysis.</p>
<h5><strong>23. Evosep Biosystems: Robust and comprehensive Protein-Protein Interaction analysis with the Evosep One</strong></h5>
<p>In this webinar we will present: In-Cell Protein Footprinting Coupled with Mass Spectrometry for Structural Biology Across the Proteome and An atlas of protein-protein interactions across mouse tissues.</p>
<h5><strong>24. Agilent Technologies: Sample Preparation Options for the Clinical Research Laboratory</strong></h5>
<p>This seminar will discuss and compare sample preparation strategies for clinical research laboratories ranging from simple dilute and shoot to solid-phase extraction (SPE).</p>
<h5><strong>25. Thermo Fisher Scientific: In-depth oligonucleotide characterization with BioPharma Finder software – intact mass analysis, oligonucleotide analysis and mRNA mapping</strong></h5>
<p>Learn how to use in-depth oligonucleotide characterization tools including automatic sequencing of MS2 data to confirm the sequence of the biotherapeutic and how to perform mRNA mapping using HR LC MS/MS.</p>
<h5><strong>26. PerkinElmer: Improving Your Canna-business: Cannabinoid Monitoring in Dried Flower by the New PerkinElmer LC300 System</strong></h5>
<p>Join PerkinElmer’s Michael Costanzo, for a look into the science of potency testing via liquid chromatography, a method to test for 16 of the most common cannabinoids, and a brief look at the new LC 300.</p>
<h5><strong>27. Agilent Technologies: MassHunter WalkUp: Making the Complex Simple, Part 2</strong></h5>
<p>This webinar explores what MassHunter WalkUp can do for your lab, highlights experience from administrator and users’ perspectives for various workflows, and demonstrates ease-of-use.</p>


LC and LCMS webinars - Week 17

<p><strong>Pesticides are chemicals that are very closely monitored and may not always be easy for an analytical chemist to monitor and detect.</strong></p>
<p>Thanks to their use in <strong>agriculture</strong> and subsequently also their cycle in <strong>environment</strong> we can find them almost everywhere. The variety of <strong>analyzed matrices</strong> is so wide, <strong>detection limits</strong> are pushing down and the field of <strong>analytical chemistry</strong> is also under pressure on <strong>sample throughput</strong>, and thus also the efficiency and economy of methods.</p>
<p>Instrumental techniques are also being developed hand in hand with these requirements, and we will look at the latest possibilities of <strong>liquid chromatographs (LC)</strong> in connection with <strong>triple quadrupole mass spectrometers (LC/QQQ)</strong> in this overview.</p>
<p>We will focus on <strong>2 main areas</strong> of these analyzes, namely food and the environment, in which you can then filter in more detail in the library, eg by combination with various separation techniques such as <strong>Supercritical Fluid Chromatography (<a href="https://lcms.labrulez.com/library?search=pesticides&amp;instrumentationItems=35-32-31-38&amp;date=2020-2021&amp;publicationTypeItems=1-2-7-5-4">SFC</a>)</strong> or take a closer look at <a href="https://lcms.labrulez.com/library?search=pesticides&amp;instrumentationItems=35-32-31-10&amp;date=2020-2021&amp;publicationTypeItems=1-2-7-5-4"><strong>sample preparation</strong></a> and suitable <a href="https://lcms.labrulez.com/library?search=pesticides&amp;instrumentationItems=35-32-31-20-34&amp;date=2020-2021&amp;publicationTypeItems=1-2-7-5-4"><strong>HPLC columns</strong></a>.</p>
<p>All documents can be found <a href="https://lcms.labrulez.com/library?search=pesticides&amp;instrumentationItems=35-32-31&amp;date=2020-2021&amp;publicationTypeItems=1-2-7-5-4"><strong>directly for download in our LabRulezLCMS library</strong></a> and to complement possible analytical techniques you can also explore similar applications using <strong>gas chromatographs (GC)</strong> in conjunction with <strong>triple quadrupole mass spectrometers (GC/QQQ)</strong> in an article on the <a href="https://gcms.labrulez.com/article/1275"><strong>LabRulezGCMS portal</strong> </a>. </p>
<p>Today, you will find almost <strong>13,000 documents</strong> in the field of <strong>analytical chemistry</strong> and <strong>separation techniques</strong> in libraries, and their number is growing every day.</p>
<h3><strong>Food &amp; Agriculture LC/QQQ</strong></h3>
<h4><strong>Applications (27)</strong></h4>
<ul>
<li><p>Determination of Anionic Polar Pesticides in Grapes using UPLC-MS with Anionic Polar Pesticide Column <strong>| 2020 | Waters</strong></p>
</li>
<li><p>Multiresidue Pesticide Analysis in Black Tea and Orange Matrix Using the Agilent 6470B Triple Quadrupole LC/MS Systém <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Evaluation of the Performance of an LC-MS/MS Method for the Determination of Anionic Polar Pesticide Residues in Crops and Foodstuffs Using an Interlaboratory Study <strong>| 2021 | Waters</strong></p>
</li>
<li><p>Multimethod Pesticide Analysis with the Agilent 1260 Infinity II Prime LC System and Agilent Ultivo Triple Quadrupole LC/MS <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Taking Advantage of the Orthogonal Selectivities of Agilent InfinityLab Poroshell 120 C18 Columns for Method Development at High pH <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Determination of Cationic Polar Pesticides and Plant Growth Regulators Using UPLC-MS/MS with the ACQUITY UPLC BEH Amide Column <strong>| 2021 | Waters</strong></p>
</li>
<li><p>Quantitation of Pesticide Residues in Milk Using the Agilent 6470 Triple Quadrupole LC/MS <strong>| 2021 | Agilent Technologies</strong></p>
</li>
<li><p>Comprehensive LC/MS/MS Workflow of Pesticide Residues in Food Using the Agilent 6470 Triple Quadrupole LC/MS System <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Analysis of Multiclass Multiresidue Pesticides in Milk Using Agilent Captiva EMR—Lipid with LC/MS/MS and GC/MS/MS <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Quantification of acetamiprid and prochloraz in black pepper using the SCIEX Triple Quad™ 3500 LC-MS/MS Systém <strong>| 2020 | SCIEX</strong></p>
</li>
<li><p>Multiresidue Method for the Quantification of Pesticides in Fruits, Vegetables, Cereals and Black Tea using UPLC-MS/MS <strong>| 2020 | Waters</strong></p>
</li>
<li><p>Analysis of Residual Pesticides (No. 1: in Soybeans) Using Triple Quadrupole LC/MS/MS <LCMSTM-8060> <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Automating the Preparation of Matrix Matched Calibration Standards for the Analysis of Food Contaminants by LC/MS/MS <strong>| 2020 | GERSTEL</strong></p>
</li>
<li><p>Determination of Chlorate and Perchlorate in Infant Milk Using Waters Anionic Polar Pesticide Column and UPLC-MS/MS <strong>| 2020 | Waters</strong></p>
</li>
<li><p>Trace-Level Analysis of Chlorates in Milk and Infant Formula <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Simultaneous Determination of Pesticide Residues in Vegetable Extract by LC/MS/MS (LCMS™-8050) <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Determination of Pesticides and Mycotoxins in Cannabis Flower as Defined by Legalized U.S. State Recreational Cannabis Regulations <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Using pH as a Method Development Tool with Agilent InfinityLab Poroshell 120 CS-C18 <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Determination of Pesticides and Mycotoxins as Defined by California State Recreational Cannabis Regulations <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Direct Analysis of Glyphosate, Glufosinate and AMPA in Foods Using a Triple Quadrupole LC/MS/MS <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>New Strategy for Glyphosate, Glufosinate, and AMPA quantification in food: In-vial addition of pairing agent <strong>| 2021 | Shimadzu</strong></p>
</li>
<li><p>Simultaneous quantification of aminoglycoside antibiotics in milk using the SCIEX Triple Quad™ 3500 LC-MS/MS System <strong>| 2020 | SCIEX</strong></p>
</li>
<li><p>Analysis of Captan, Folpet, and their Derivatives in Food with APCI-LCMS™-8060 <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>The Analysis of Sudan and other Azo Dyes in Spices Using Liquid Chromatography - Tandem Quadrupole Mass Spectrometry <strong>| 2021 | Waters</strong></p>
</li>
<li><p>Quick Screening and Quantitative Analysis of Carcinogens in Medicinal Plants Using DPiMS™-8060 <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Analysis of Mycotoxins in Cannabis Plant Material and Derivative Products by Immunoaffinity Enrichment LC-MS/MS <strong>| 2021 | Waters</strong></p>
</li>
<li><p>LC-MS/MS Method Development and Validation for the Quantitative Determination of Regulated Mycotoxins in Cereal Grain Flours Using Simplified Sample Preparation Conditions on Xevo TQ-XS <strong>| 2020 | Waters</strong></p>
</li>
</ul>
<h4><strong>Posters (13)</strong></h4>
<ul>
<li><p>Analysis of the California list of Pesticides and Mycotoxins in Edibles <strong>| 2020 | Restek</strong></p>
</li>
<li><p>Analytical Solutions for Food Safety – a Closer Look in the Analytical Toolbox <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>California and Oregon’s Complete Residual Pesticide Analysis using a Shimadzu LCMS-8060 <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Efficient introduction of ionic compounds into LC-MS using the improved ESI unit; Application to dirty samples <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Detection of typical GCMS Pesticides in Cannabis Matrix utilizing APCI-LCMS <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Quantification of Glyphosate, Glufosinate, and AMPA in Food via In-vial Addition of Pairing Agent <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>ROUTINE DETERMINATION OF HIGHLY POLAR CATIONIC PESTICIDES AND PLANT GROWTH REGULATORS BY LC-MS/MS <strong>| 2020 | Waters</strong></p>
</li>
<li><p>EVALUATING SYSTEM PERFORMANCE DURING ROUTINE ANALYSIS OF FOOD COMMODITIES FOR PESTICIDE RESIDUES <strong>| 2020 | Waters</strong></p>
</li>
<li><p>EXPLORING THE ANALYTICAL SCOPE OF PESTICIDES, IONIZABLE IN A SINGLE INJECTION BY LC-MS/MS <strong>| 2020 | Waters</strong></p>
</li>
<li><p>Agilent ASMS 2020 Posters Book <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Direct Analysis of Glyphosate, Glufosinate and AMPA in Foods Using a Triple Quadrupole LC/MS/MS <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Analysis of Captan, Folpet and their derivatives in food with APCI-LCMS-8060 <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Highly sensitive direct analysis of glyphosate, glufosinate and AMPA in the beverages by LC-MS/MS <strong>| 2020 | Shimadzu</strong></p>
</li>
</ul>
<h4><strong>Guides (5)</strong></h4>
<ul>
<li><p>Confidently Analyze Cannabis Flower and Hemp - Application compendium for cannabis potency and safety <strong>| 2020 | Agilent Technologies</strong></p>
</li>
<li><p>Solutions for Flexible Work Styles LCMS Food Safety Applications <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Waters Application Notes - Food Testing <strong>| 2020 | Waters</strong></p>
</li>
<li><p>Waters ACQUITY UPC2 Bibliography - A compendium of references to scientific journal articles based on the technique of UltraPerformance Convergence Chromatography (UPC2) <strong>| 2020 | Waters</strong></p>
</li>
<li><p>Food integrity application compendium <strong>| 2020 | Thermo Fischer Scientific</strong></p>
</li>
</ul>
<h3><strong>Environmental</strong></h3>
<h4><strong>Applications (5)</strong></h4>
<ul>
<li><p>Determination of Anionic Polar Pesticides in High Water Foodstuffs <strong>| 2020 | Waters</strong></p>
</li>
<li><p>Measurement of Underivatized Glyphosate and Other Polar Pesticides in Surface and Drinking Water <strong>| 2021 | Agilent Technologies</strong></p>
</li>
<li><p>Determination of Oxyanions in Drinking Water by Direct Injection Using Liquid Chromatography-Tandem Quadrupole Mass Spectrometry <strong>| 2021 | Waters</strong></p>
</li>
<li><p>Analysis of Captan, Folpet and Their Derivatives in Water by APCI-LCMS™-8060 <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>An Alternative Ionization Technique for Perfluorinated Alkyl Substance (PFAS) Analysis: Evaluating UniSpray for Water and Soil Samples <strong>| 2020 | Waters</strong></p>
</li>
</ul>
<h4><strong>Posters (2)</strong></h4>
<ul>
<li><p>Trace analysis of abused drugs in waste water sample by AOE system coupled with LCMS-8060 <strong>| 2020 | Shimadzu</strong></p>
</li>
<li><p>Towards Single System for Total Water Analysis. LC-MS/MS screening of 325 PPCP Contaminants in Tap and Surface Water <strong>| 2020 | Shimadzu</strong></p>
</li>
</ul>
<h4><strong>Presentations (1)</strong></h4>
<ul>
<li>Measurement of Underivatized Glyphosate and Other Polar Pesticides in Aqueous Matrices Using LC-TQ <strong>| 2020 | Agilent Technologies</strong></li>
</ul>
<h4><strong>Guides (1)</strong></h4>
<ul>
<li>Waters ACQUITY UPC2 Bibliography - A compendium of references to scientific journal articles based on the technique of UltraPerformance Convergence Chromatography (UPC2) <strong>| 2020 | Waters</strong></li>
</ul>


Overview of LC/QQQ applications of pesticide analysis - Food and Environment (2020-2021)

<p><strong>In the week from May 3, 2021, the following webinars await you in the field of LC and LCMS.  More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:</strong></p>
<p><strong>Search and filter</strong> in more than <strong>900 LC and GC webinars</strong>.</p>
<h5><strong>1. Agilent Technologies: Extend the possibilities with Agilent’s OpenLab CDS using SLIMS for Sample Management</strong></h5>
<p>Learn how SLIMS can be used in conjunction with Agilent’s OpenLab CDS for digitalizing your lab operations with an overview of the entire system and a demonstration.</p>
<h5><strong>2. Agilent Technologies: 2021 Agilent Science and Technology Virtual Symposium</strong></h5>
<p>Advancing Science Together. Innovation in life science and applied chemicals with you in mind. ASTvS 2021 is live across several continents.</p>
<h5><strong>3. New Food magazine/Metrohm International: Improving your analytics for beverage analysis with ion chromatography</strong></h5>
<p>We will begin with an overview of the latest analytical techniques used for beverage analyses and the presenters will then take a closer look at the benefits of ion chromatography for beverage analysis.</p>
<h5><strong>4. Mestrelab Research: Semi-automated LC-MS interpretation of DNA conjugates in 96 or 384 well plates</strong></h5>
<p>Roberto Martinez from Novartis (Basel) will give you a short introduction to the QC Profiling plugin, for semi-automated LCMS interpretations of DNA conjugates.</p>
<h5><strong>5. Agilent Technologies: LCMS Big Data: Experimental Design, Data Processing, and Alignment</strong></h5>
<p>This webinar will focus on Qualitative Analysis 10 and Profinder 10 and how these two software programs are connected and crucial to scientist’s workflows.</p>
<h5><strong>6. Agilent Technologies: Why Good Chromatography Matters for LCMS</strong></h5>
<p>This introduction webinar starts at the beginning by illustrating the optimal configuration of LC modules and LC capillary tubing to ensure lowest peak broadening to take place prior to MS detection.</p>
<h5><strong>7. SelectScience/Waters Corporation: Enhancing LC-MS analysis of oligos, peptides, and glycans using hybrid surface technology</strong></h5>
<p>In this webinar, a team of scientists from Waters Corporation will describe the benefits of the ACQUITY PREMIER Solution with MaxPeak HPS Technology in mitigating problematic metal interactions. </p>


LC and LCMS webinars - Week 18

Article

Product

Events

Webinars

Application

Academy

Video

Poster

Scientists

Plastics

Environment

Food

Water

Health

Presentation

Scientific article

Interview

Toxicology

Popularization

Science and research

Software

Covid-19

Career

Laboratories

Various

Zaměření

Type of News

Focus

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.

LC and LCMS webinars - Week 18

Overview of LC/QQQ applications of pesticide analysis - Food and Environment (2020-2021)

LC and LCMS webinars - Week 17

LC/MS Unknown Identifications Using MSMS Libraries Part VI: MS Interpreter Correlation of Substructure to MSMS Ions

LC and LCMS webinars - Week 16

LC and LCMS webinars - Week 15

LC and LCMS webinars - Week 14

LC and LCMS webinars - Week 13

LC/MS Unknown Identifications Using MSMS Libraries Part V: NIST Structure Searches

LC and LCMS webinars - Week 12

Upcoming events

Restek at EPRW 2026

16th European Pesticide Residue Workshop (EPRW 2026)

Thermo Fisher Scientific at HPLC 2026

Webinars

Biopharma fundamentals: Fragment analysis by CE

Proteome Discoverer 3.3 SP1: Processing DIA data with DIA-NN node

Improving RNA Purity and Measurement for Reliable Bioprocessing