Dear friends and fans of mass spectrometry,
The history of a method for studying of matter known as mass spectrometry dates back more than a century. The foundations have mostly been laid by physics studying discharges in gases. After about five decades mass spectrometry entered the domain of chemistry and evolved into an excellent tool for studying the structure of chemical compounds. Recently we are witnessing its expansion into the field of cellular, molecular, and structural biology. The technology of mass spectrometry developed immensely over the time. Let us take a tour into the history and learn about the past technologies. Let us explore the state-of-art mass spectrometry.
A technical museum focused on unique and significant part of science, the Czech Museum of Mass Spectrometry will display and explain laboratory instrumentation that encompasses physics, chemistry, engineering and informatics and combines them into a device that contributes to many parts of our daily life.
Czech and English speaking visitors will have an opportunity to learn about the principles and applications of mass spectrometry, its history, and important scientists including Nobel price winners, while experiencing a remarkable collection of mass spectrometers. Founded by mass spectrometry enthusiasts Jaroslav Pol (Thermo Scientific) and Josef Cvacka (Institute of Organic Chemistry and Biochemistry) and sponsored by Frantisek Turecek (University of Washington, Seattle), the Czech Museum of Mass Spectrometry is now being assembled and will open in Prague in 2017. Donations of mass spectrometry artifacts are gratefully appreciated; those willing to contribute please contact the curators.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/d3e7627196634c0a8fa129f95fef6edd/obrazek.png" alt="The Czech Museum of Mass Spectrometry"/>
<h3>Mass spectrometry</h3>
Study of matter through the formation of gas-phase ions that are characterized using mass spectrometers by their mass, charge, structure, and/or physico-chemical properties.
<h3>Mass Analyzers</h3>
<h5>Fourier Transform Ion Cyclotron Resonance</h5>
Mass spectrometer based on the principle of ion cyclotron resonance in which an ion in a magnetic field moves in a circular orbit at the cyclotron frequency that is characteristic of its m/z value. Ions are coherently excited to a larger radius orbit using a pulse of radio frequency electric field, and their image charge is detected on receiver plates as a time domain signal. Fourier transformation of the time domain signal results in a frequency domain signal that is converted to a mass spectrum based on the inverse relationship between cyclotron frequency and m/z.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/1628c6d87adf47538f70c2d7ce971db9/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Ion Trap</h5>
Device for spatially confining ions using electric and magnetic fields alone or in combination.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/bcc0887a778f4df29f488bcd87ce8718/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Linear Ion Trap</h5>
Two-dimensional Paul ion trap in which ions are confined in the axial dimension by means of a static electric potential.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/6d35a6cdb4ee4baa95ad2d831b20db19/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Orbitrap</h5>
Ion trapping device that consists of an outer barrel-like electrode and a coaxial inner spindle-like elec- trode that form an electrostatic 
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/4c8de0a71fef446fa44829e9d37c8b62/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Sector</h5>
Device that produces a magnetic field perpendicular to a charged particle beam that deflects the beam to an extent that is proportional to the ratio of particle momentum and charge.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/240ae6e09cb443508bf7dce8309b2928/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Time of Flight</h5>
Mass spectrometer that separates ions by m/z in a field-free region after acceleration through a fixed accelerating potential. Ions of the same initial translational energy and different m/z require different times to traverse a given distance in the field-free region.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/0d0eaa3a8aa544d1abcca833a9e6e9ae/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Triple Quadrupole</h5>
Tandem mass spectrometer comprising two transmission quadrupole mass spectrometers in series, with a (non-selecting) RF-only quadrupole (or other multipole) between them to act as a collision cell.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/b6e4bd36ccb44cd8a93e84353b28a357/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h3>Ion Sources</h3>
<h5>Atmospheric pressure chemical ionization</h5>
Atmospheric pressure chemical ionization (APCI) is chemical ionization of a sample that is a gas or nebulized liquid, using an atmospheric pressure corona discharge or beta emitter such as 63Ni.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/d562c1ce1a9f43c78d8a93a2c6c43932/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Atmospheric pressure photoionization</h5>
Atmospheric pressure photoionization (APPI) is direct ionization of molecules at atmospheric pressure by electron detachment induced by photons forming M+•, or atmospheric pressure chemical ionization in which the reactant ions are generated by photoionization of suitable dopant species and subsequent ion/molecule reactions of their molecular ions.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/828a17ec377a4313bdd59f9275192e87/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Desorption electrospray ionization</h5>
Desorption electrospray ionization (DESI) is formation of gas-phase ions from a solid or liquid sample at atmospheric pressure through the inter- action of electrosprayed droplets with the sample surface.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/86624af57b96403586bd27b3bafccec3/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Electrospray ionization</h5>
Electrospray ionization (ESI) is spray ionization process in which either cations or anions in solution are transferred to the gas phase via formation and desolvation at atmospheric pressure of a stream of highly charged droplets that result from applying a potential difference between the tip of the electrospray needle containing the solution and a counter electrode.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/673ec39a73b64561805cf60670486635/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Fast atom bombardment ionization</h5>
Fast atom bombardment ionization (FAB) is ionization of molecules initiated by a beam of neutral atoms with translational energies in the keV range. Labile molecules susceptible to dissociation are dissolved in an involatile liquid matrix that absorbs the energy of the bombarding atoms to form a selvedge region above the liquid surface in which ionization of the molecules occurs.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/afda171085f54f6e856bc930cf873fca/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Matrix-assisted laser desorption/ionization</h5>
Matrix-assisted laser desorption/ionization (MALDI) is formation of gas-phase ions from molecules present in a solid or liquid matrix that is irradiated with a laser. The matrix is a material that absorbs the laser energy and promotes ionization.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/39f899169e27496f938621f0d25a0f12/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>
<h5>Secondary ion mass spectrometry</h5>
Secondary ion mass spectrometry (SIMS) is technique in which a focused beam of primary ions produces secondary ions by sputtering from a solid surface. The secondary ions are analyzed by mass spectrometry.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/fd584fd784ab4c5197b461de5c42c5ee/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/>

The Czech Museum of Mass Spectrometry

The origins of mass spectrometry in Czechia date back to the 1950s when a group of young scientists in the newly founded Czechoslovak Academy of Sciences started to build the first mass spectrometer in the country. Over the years, mass spectrometry gradually developed and gained in importance. The conference will explore the history, status and perspectives of mass spectrometry. It will mark the opening of the Czech Mass Spectrometry Museum and contribute to celebrations of 70th anniversary of mass spectrometry in our region.
<h3>Organizing institutions</h3>
<a href="https://gcms.cz/companies/22">ÚOCHB/IOCB PRAGUE</a>
<a href="https://gcms.cz/companies/21">Czech Society for Mass Spectrometry/Česká společnost pro hmotnostní spektrometrii</a>
<a href="https://gcms.cz/companies/7">Ioannes Marcus Marci Spectroscopic Society/Spektroskopická společnost Jana Marka Marci</a>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/03cce7b42575402eb5c91750579dec76/obrazek.png" alt="ÚOCHB/IOCB PRAGUE - Czech Society for Mass Spectrometry/Česká společnost pro hmotnostní spektrometrii - Ioannes Marcus Marci Spectroscopic Society/Spektroskopická společnost Jana Marka Marci"/>
<h3>Conference program</h3>
Available on <a href="http://ms-prague2020.uochb.cas.cz/program.php">Prague Meeting on Historical Perspectives of Mass Spectrometry website</a>
<h3>Venue</h3>
The conference will take place in three localities in Prague districts Dejvice and Bubeneč: National Library of Technology (lectures), Institute of Organic Chemistry and Biochemistry of the CAS (vernissage tours), and Old Wastewater Treatment Plant (poster session &amp; dinner).
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/0827c374acec4191b3ff1610c02ae928/obrazek.png" alt="ÚOCHB/IOCB PRAGUE: Prague Meeting on Historical Perspectives of Mass Spectrometry"/>
<h3>Czech Museum of Mass Spectrometry</h3>
The museum aims to collect and display artifacts related to mass spectrometry, especially those associated with our geographical region. The technical museum shows key components of mass spectrometers used in the past and in contemporary laboratory practice, and it also displays historical documents, photographs, books, etc. The museum&#39;s mission is expressed in two words: education and inspiration. It demonstrates technologies hidden behind the cover and inside the vacuum systems, thus allowing a better understanding how the mass spectrometers actually work. Displayed technical solutions, prototypes, ideas, and stories can be inspiring for students, scientists, and designers of instruments.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/8619b6eab01a4ec18b531bf1a7d20dff/obrazek.png" alt="ÚOCHB/IOCB PRAGUE: Czech Museum of Mass Spectrometry"/>
<h3>Exhibition</h3>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/3bc183e590444d81a74ce5538a9b5b59/obrazek.png" alt="ÚOCHB/IOCB PRAGUE: Czech Museum of Mass Spectrometry"/>
<h3>Website</h3>
The <a href="http://www.ms-museum.org/">website</a> will store the museum database with a detailed description of exhibits and bring topics from MS history.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/c4771b1119d84181929ea3cd97c56e76/obrazek.png" alt="ÚOCHB/IOCB PRAGUE: Czech Museum of Mass Spectrometry"/>
<h3>Donations</h3>
The Czech Museum of Mass Spectrometry welcomes donations to its collection: instruments or their parts (broken, damaged, unused), and documents, photographs or books related to MS history.

Prague Meeting on Historical Perspectives of Mass Spectrometry and  the Czech Mass Spectrometry Museum

In the week from September 14, 2020, the following webinars await you in the field of LC and LCMS:
Mo, 14.9.2020, 17:00 (CEST - Prague) (LCGC/Phenomenex)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/323">Practical Method Development Strategies for the Characterization of Proteins by Intact and Subunit Reversed Phase HPLC</a></li>
</ul>
Mo, 14.9.2020, 19:00 (CEST - Prague) (Agilent Technologies)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/303">MassHunter User Group Meeting: Parameters for Sensitive and Rugged Data Acquisition</a></li>
</ul>
Tu, 15.9.2020, 11:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/286">Moving forward webinar part 1 - remote instrument service</a></li>
</ul>
Tu, 15.9.2020, 19:00 (CEST - Prague) (Phenomenex)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/320">Role of Column Morphology, Bonded Phase in RP Chromatography</a></li>
</ul>
Tu, 15.9.2020, 17:00 (CEST - Prague) (LCGC/Waters)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/301">Advancing N-Glycan Analysis of Next Generation Biotherapeutics with Optimized Protocols and Easy Automation</a></li>
</ul>
Wed, 16.9.2020, 11:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/287">Moving forward webinar part 2 - chromatography software</a></li>
</ul>
Wed, 16.9.2020, 19:00 (CEST - Prague) (Agilent Technologies)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/304">MassHunter User Group Meeting: Data Processing Algorithms</a></li>
</ul>
Th, 17.9.2020, 11:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/288">Moving forward webinar part 3 - compliance</a></li>
</ul>
Th, 17.9.2020, 16:00 (CEST - Prague) (LCGC/MilliPORE SIGMA/Markes International/Biotage/Frontier Lab/GERSTEL)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/296">Advances in Sample Preparation: Part 1 - Automated Sample Preparation for HPLC and GC Users</a></li>
</ul>
Fr, 18.9.2020, 16:00 (CEST - Prague) (LCGC/MilliPORE SIGMA/Markes International/Biotage/Frontier Lab/GERSTEL)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/297">Advances in Sample Preparation: Part 2 - The Importance of Sample Preparation in Liquid Chromatography (LC) and Gas Chromatography (GC)</a></li>
</ul>
Fr, 18.9.2020, 19:00 (CEST - Prague) (Agilent Technologies)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/305">MassHunter User Group Meeting: Advanced Data Processing Topics: Tips and Tricks</a></li>
</ul>
In the week from 21st of September, there are 13 other webinars waiting for you in the field of GC and GCMS, which you will find in the section <a href="https://lcms.labrulez.com/webinars">Webinars</a>.

LC and LCMS webinars - Week 38

In the week from September 21, 2020, the following webinars await you in the field of LC and LCMS:
Po, 21.9.2020, 18:00 (CEST - Prague) (Agilent Technologies)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/358">OpenLab CDS Introductory Demonstration</a></li>
</ul>
Po, 21.9.2020, 15:00 (CEST - Prague) (LCGC/Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/326">Building a More Efficient Routine Lab: Approaches to Modernizing HPLC Methods with New Technologies</a></li>
</ul>
Po, 21.9.2020, 19:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/309">Advanced Ion Chromatography Solutions for Environmental Analysis including Fast, Direct Injection of HAAs in Drinking Water with IC-MS/MS</a></li>
</ul>
Po, 21.9.2020, 19:00 (CEST - Prague) (Agilent Technologies)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/306">MassHunter User Group Meeting: MassHunter Quantitative Analysis/Collateral – help, videos, and report examples</a></li>
</ul>
Út, 22.9.2020, 10:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/378">LC-MS User Meeting 2020 - Omics - Plenary Session</a></li>
</ul>
Út, 22.9.2020, 12:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/379">LC-MS User Meeting 2020 - Omics/Proteomics Morning Session</a></li>
</ul>
Út, 22.9.2020, 15:00 (CEST - Prague) (LCGC/Agilent Technologies)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/302">How to Achieve a Fully Digital, End-to-End Analytical Workflow</a></li>
</ul>
Út, 22.9.2020, 15:30 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/380">LC-MS User Meeting 2020 - Omics/Proteomics Afternoon Session</a></li>
</ul>
Út, 22.9.2020, 17:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/310">Use of EQuan Orbitrap HRAM LC-MS to Fulfill the Requirements of the EU Water Framework Directive’s Chemical Investigation Programme Phase 3 (CIP3)</a></li>
</ul>
Út, 22.9.2020, 19:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/311">PFAS Can Be Anywhere, We Can Help You Find It</a></li>
</ul>
St, 23.9.2020, 10:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/375">LC-MS User Meeting 2020 - Clinical Toxicology - Plenary Session</a></li>
</ul>
St, 23.9.2020, 12:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/376">LC-MS User Meeting 2020 - Clinical Toxicology - English Morning Session</a></li>
</ul>
St, 23.9.2020, 15:30 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/377">LC-MS User Meeting 2020 - Clinical Toxicology - English Afternoon Session </a></li>
</ul>
St, 23.9.2020, 16:00 (CEST - Prague) (The Analytical Scientist/Tosoh Bioscience)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/316">LenS3 – MALS Technology for Next Generation Biopharmaceuticals</a></li>
</ul>
St, 23.9.2020, 17:00 (CEST - Prague) (LCGC/Phenomenex)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/295">Improved LC-MS/MS from Biological Samples Using Advancements in SPE</a></li>
</ul>
St, 23.9.2020, 19:00 (CEST - Prague) (Phenomenex)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/338">Miniaturized Separations and Increased Sensitivity – What to Expect when Moving to Micro and Nano Scale HPLC (North America)</a></li>
</ul>
St, 23.9.2020, 19:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/312">Expanding Microcystin Analyses to Include Other Toxic Cyanopeptides using Online Concentration LC-MS/MS</a></li>
</ul>
St, 23.9.2020, 19:00 (CEST - Prague) (Agilent Technologies)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/307">MassHunter User Group Meeting: LC/MS QQQ acquisition / MassHunter Quantitative Analysis</a></li>
</ul>
St, 23.9.2020, 20:00 (CEST - Prague) (Technology Networks/Bruker)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/314">Advancing Top-Down Proteomics for Precision Medicine on the timsTOF Pro</a></li>
</ul>
Čt, 24.9.2020, 10:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/373">LC-MS User Meeting 2020 - Environmental &amp; Food Safety - Plenary Session</a></li>
</ul>
Čt, 24.9.2020, 12:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/374">LC-MS User Meeting 2020 - Environmental &amp; Food Safety - English Session</a></li>
</ul>
Čt, 24.9.2020, 18:00 (CEST - Prague) (Agilent Technologies)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/363">Practical Approaches to Preparative Chromatography</a></li>
</ul>
Pá, 25.9.2020, 12:00 (CEST - Prague) (Shimadzu)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/354">Shimadzu Advances in Liquid Chromatography - Session 2: Advances in Detectors</a></li>
</ul>
Pá, 25.9.2020, 17:00 (CEST - Prague) (SelectScience/Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/319">Analytical Workflows for Anti-Doping, Using LC Tools</a></li>
</ul>
Pá, 25.9.2020, 21:00 (CEST - Prague) (Thermo Fisher Scientific)
<ul>
<li><a href="https://lcms.labrulez.com/webinar/285">Software Solutions for Environmental Laboratories to Fit Your Every Need</a></li>
</ul>

LC and LCMS webinars - Week 39

In the week from September 28, 2020, the following webinars await you in the field of LC and LCMS. More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:
1. SelectScience/Waters: Taming the Viral Beast: Applying LC and LC-MS Technologies to the Analysis of rAAV Viral Vectors
2. LCGC/Postnova: Applications of Field-Flow Fractionation in Drug Delivery Analysis
3. Agilent Technologies: Advance Your Lab Operation: Minimize Regulatory Risk by Moving to a Customized Instrument Qualification Solution
4. Phenomenex: Overview of Sample Preparation Options for the Pharmaceutical Industry
5. Wiley: How do you prefer your Brew? LCMS and GCMS approaches to flavor discovery of coffee
6. Thermo Fisher Scientific: Method development for SPE utilizing new SOLA 30 mg cartridges
7. The Analytical Scientist/Thermo Fisher Scientific: Elevating quantitative and qualitative LC-MS analysis of pesticide residues to a new level with the new Exploris HRAM MS system
8. LCGC/Agilent Technologies: Process Analytical Technology (PAT): Online Monitoring and Control of Upstream Titer, Product Quality and Amino Acid Content Using 2D-LC with SegFlow Interface
9. Agilent Technologies: Agilent Approaches for Amino Acid Analysis
10. Shimadzu: Shimadzu Advances in Liquid Chromatography - Session 3: UHPLC 2
11. LCGC/Phenomenex: Method Development for the Characterization of Synthetic Oligonucleotides by LC-MS

LC and LCMS webinars - Week 40

The TRILAB DeltiQ 2, 3D printer from the Brno-Hradec Králové company TRILAB is a high-quality 3D printer from the so-called pro-sumer segment of the desktop 3D printer category. It is a printer completely developed by TRILAB, designed and built only from high-end components. Its hardware and software is adapted and tuned for short, but also multi-day prints even without the presence of an operator. Thanks to the remote-control software and the built-in camera with lighting, the user is constantly in control of printing. Also in the case of ambiguity, question or problem, the printer is immediately remotely diagnosed by the TRILAB service team.
Thanks to the technical and application support of the TRILAB team and also thanks to the many years of experience of the two main partners of TRILAB in the field of science and research, where Dr. Vojtěch Tambor is originally the leading researcher in the laboratory of the Center for Biomedical Research (CBV) of the University Hospital HK and Dr. Michal Boháč is a former director of Bruker s.r.o., every scientific customer is always perfectly professionally secured and can thus focus only on solving their own challenges and projects.
Thanks to practical experience with placing 3D printers in research laboratories, TRILAB also knows very well that the DeltiQ 3D printer does not only allow its owners to save time and money in producing things that are familiar and hard to reach, but also and above all to create and quickly test completely new things, not yet discovered. In addition, it allows them to be pampered by the quality of the printing surface, spatial accuracy, huge print volumes or even just the grace of delta kinematics movements. In addition, the customer does not have to buy the printer as an investment, but can rent it or cleverly buy it under an initial operating lease with a possible subsequent purchase. This not only divides the financial costs of its acquisition over a longer period, but also avoids possible lengthy approval processes for investment purchases.
The DeltiQ 3D printer will become a great help in your research project. Whether it&#39;s simple holders or specialized components, with a 3D printer you can save not only most acquisition costs, but also a lot of time spent looking for a suitable tool. In addition, you can create tools that you cannot buy as they do not exist! And besides tools, you can also create your own prototypes, products or their models and replacements.
<h3>The story of <a href="https://www.nenovision.com/">NenoVision</a>: Thanks to 3D printing, our microscope can be touched safely</h3>
NenoVision is a start-up originating from the Central European Institute of Technology CEITEC and is one of the incubated companies in the South Moravian Innovation Center JIC INMEC. They are proud that their LiteScope microscope is the only one in the world that can combine data from an electron microscope and an atomic force microscope in detail and assemble them into 3D models. It literally opens up a new dimension of research.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Trilab_Neno_Vision_mikroskop_1_6b79421014/Trilab-NenoVision-mikroskop-1.jpg" alt="TRILAB: NenoVision - model of LiteScope microscope printed on the TRILAB DeltiQ printer"/>
The company found the application of 3D printing in solving the problem of how to enable the &quot;touch&quot; of the microscope to partners, customers and the professional public: &quot;LiteScope normally works in a controlled environment, moreover in a vacuum, and it is a sensitive and very expensive device. Therefore we or our distributors cannot normally carry it to all events and exhibitions, nor provide it to our partners for tests for insertion into their machines,” explains Jan Neumann, the owner and CEO of NenoVision.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Trilab_Neno_Vision_mikroskop_2_8d96758735/Trilab-NenoVision-mikroskop-2.jpg" alt="TRILAB: NenoVision - model of LiteScope microscope printed on the TRILAB DeltiQ printer"/>
Machining the individual components of the microscope itself is so expensive that even making a copy of the instrument without &quot;living&quot; components does not make sense. In the end, 3D printing proved to be an elegant solution: “Since the complete 3D model for production was already ready, it was enough to prepare and print it on a TRILAB DeltiQ printer and the model of the device in perfect quality and accuracy was born. In this way, it can be easily reproduced and shown to customers and the public at a fraction of the normal cost,” adds Jan Neumann. 
<h3><a href="https://www.biocev.eu/en">BIOCEV</a> story: Own online nanospray built in a few days?</h3>
The story of <a href="http://peterslab.org">Dr. Petr Novák</a> from BIOCEV shows the second group of 3D printing options. Building something that does not exist, that you cannot buy, and you know what it should look like and you need it. Dr. Novák&#39;s team happened to be in exactly the same situation. Commercially available nanosprays did not meet the requirements not only in terms of compatibility with available spectrometers, but also in terms of real sensitivity, essential for measurement. That&#39;s why the &quot;Do it yourself&quot; mode came into play. Thanks to the clever use of 3D printing, a nanospray was created, which has ncomparably higher sensitivity and operator comfort compared to all commercial devices available on the market. 
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Trilab_BIOCEV_online_nanosprej_1_ac1e93326c/Trilab-BIOCEV-online-nanosprej-1.jpg" alt="TriLab: BIOCEV - online nanospray"/>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Trilab_BIOCEV_online_nanosprej_2_ba9dbfde99/Trilab-BIOCEV-online-nanosprej-2.jpg" alt="TriLab: BIOCEV - online nanospray"/>
<h3>The story of the MALDI-TOF plate suitable not only for affinity chromatography</h3>
As part of the projects of AffiPro, a spin-off company under BIOCEV Prague, it has been running for several years under the leadership of Dr. Petr Novák and Dr. Petr Pompach for the development of clinical applications of affinity chromatography on MALDI-TOF spectrometry, for example MALDI Biotyper devices, by patented application of various antibodies to MALDI plates using the so-called soft ion landing technology. Although this is a technology that is just beginning and commercial use is yet to come, they already have several very interesting surfaces on their own chips in the laboratory, which will be interesting in the future not only for clinical and veterinary, but also for military screening. And thanks to the use of 3D printing technology, they have the opportunity to print not only different surfaces and shapes, but also to use different materials on MALDI chips and thus, for example, increase the sensitivity and detection limits of the method. 
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Trilab_Affi_Pro_MALDI_TOF_desticka_836e1e69b7/Trilab-AffiPro-MALDI-TOF-desticka.png" alt="TriLab: AffiPro/BIOCEV - MALDI-TOF chip for affinity chromatography"/>
The original article <a href="https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.0c01737">Three-Dimensional Printed Target Plates for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry ke stažení.</a>

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The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

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