After SPE, samples may not be ready for direct LC injection. Solvent mismatch with the mobile phase can distort peak shapes—proper solvent choice is essential.
We, 24.9.2025
Phenomenex
Article | Academy
Collision-Based Ion-activation and Dissociation
Collision-based ion activation, developed nearly 80 years ago, remains the most widely used fragmentation method. Learn about three key techniques on Thermo Scientific MS.
Tu, 23.9.2025
Thermo Fisher Scientific
Article | Product
How to calculate Signal to Noise ratio in Clarity Chromatography Software
Step-by-step guide to calculating signal-to-noise ratio in Clarity CDS. Learn how to evaluate noise, configure result tables, and assess peak quality.
Tu, 23.9.2025
DataApex
Scientific article | Science and research
Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
Ion-pairing HILIC improves impurity profiling of therapeutic oligonucleotides. It resolves deaminated impurities from full-length products, beyond current LC-MS limits.
Science is great, sharing it is rewarding, say CXI TUL chemists
CXI TUL researchers tackle PFAS removal using cyclodextrins and share their work on Instagram. Their videos connect science with the public and highlight lab research.
Fr, 19.9.2025
CXI TUL
Article | Product
How Nitrogen Blowdown Supports the SCIEX Lipidyzer Platform: Enhancing Lipidomics Sample Preparation
Nitrogen blowdown ensures gentle solvent removal in SCIEX Lipidyzer workflows, preserving delicate lipid species and boosting reproducibility in lipidomics research.
Th, 18.9.2025
Organomation
Article | Application
News from LabRulezLCMS Library - Week 38, 2025
This week we bring you application notes by Agilent Technologies, Shimadzu and Waters Corporation and poster by Thermo Fisher Scientific / HPLC Symposium!
We, 17.9.2025
LabRulez
Article | Academy
I am getting low recovery in my SPE method, how do I fix the problem?
Practical troubleshooting guide for low recovery in SPE methods. Learn how to identify problems with solvents, flow rate, pH, or sorbent choice step by step.
We, 17.9.2025
Phenomenex
Article | Science and research
Freedom to Fragment: Introduction
Discover why fragmentation is vital in mass spectrometry for peptide sequencing, protein characterization, and advanced proteomics applications.