At the January 2025 CFSRE Seized Drugs Symposium, a Thermo Fisher Scientific–sponsored workshop showcased the potential of <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2240">Thermo Scientific VeriSpray PaperSpray mass spectrometry </a>(PS-MS) to transform drug analysis workflows in both forensic and clinical toxicology. Three researchers from King’s College London (KCL)—PhD candidate Stefania Boccuzzi and MSc graduates Marwa AlJanahi and Saeed Almheiri—presented their findings on how to optimise this cutting-edge technique for faster, more sensitive, and more cost-effective detection of drugs of abuse.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_040182cb06.jpg" alt="Thermo Fisher Scientific: Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry: Thermo Fisher Scientific’s Edward Goucher and Alexandra Graham pictured beside KCL’s Stefania Boccuzzi and Vincenzo Abbate" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_040182cb06.jpg 245w," sizes="100vw" width="1024" height="512"><h3>Why VeriSpray? A simpler, faster path to results</h3>Traditional LC-MS workflows can be powerful, but when labs are overwhelmed by backlogs, the time and complexity of sample preparation and chromatography can be limiting. VeriSpray offers a remarkably simplified path to MS analysis, directly ionizing complex matrices using a paper substrate—no LC step required.<h5>Key benefits include:</h5><ul><li>&lt;2-minute results thanks to minimal sample prep and elimination of LC</li><li>Reduced cost per test by cutting solvent use and simplifying training requirements</li><li>Automation-ready with support for unattended operation of up to 240 samples</li><li>Seamless integration with Thermo Scientific triple quadrupole systems</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_2_eb1f7dacc2.jpg" alt="Thermo Fisher Scientific: Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_2_eb1f7dacc2.jpg 245w," sizes="100vw" width="700" height="317"><h3>Enhancing emergency toxicology with direct MS analysis</h3>In the emergency room, timely drug identification is critical, but clinicians often rely on patient self-report or symptom-based assessments. Stefania’s PhD research seeks to change that. Her team is developing a rapid, extraction-free method using VeriSpray PS-MS for the targeted analysis of plasma samples from patients presenting with acute drug toxicity.By using dried matrix spots on a paper substrate and coupling this with a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/404">Thermo Scientific TSQ Altis Plus Triple Quadrupole Mass Spectrometer</a>, Stefania’s work provides an alternative screening technique to chromatography, delivering faster, actionable results to guide early clinical decision-making.<h5>Key takeaways:</h5><ul><li>Paper spray MS is an ambient ionization technique suitable for emergency toxicology due to its rapid results and minimal sample prep.</li><li>Enhancing the paper substrate and adding microextraction steps can boost sensitivity without sacrificing speed.</li></ul><h3>Substrate matters: boosting detection with paper treatment</h3>One key limitation of PS-MS is the interference that can arise from the paper substrate itself. Marwa’s research explored nine different paper treatments, ranging from acids to solvents, to improve the signal-to-blank (S/B) ratio when analyzing eight common drugs in whole blood.The most promising results came from formic acid and nitric acid treatments, which significantly enhanced analyte detection. Although these methods are currently time-consuming, Marwa envisions future industrial-scale production of pre-treated cartridges to support scalable clinical workflows.<h5>Key takeaways:</h5><ul><li>Substrate optimization can significantly reduce background noise in PS-MS analysis.</li><li>Acid-treated paper enhances S/B ratios, enabling more reliable detection of drugs in blood.</li><li>Industrial pre-treatment could make these improvements broadly accessible.</li></ul><h3>DLLME meets paper spray: improving sensitivity in plasma</h3>Saeed Almheiri’s presentation focused on dispersive liquid-liquid microextraction (DLLME) as a sample prep technique to increase sensitivity for PS-MS analysis of drugs in plasma, without adding significant complexity to the workflow.Using DLLME prior to VeriSpray analysis, Saeed demonstrated improved detection limits (as low as 0.3 ng/mL) across a panel of 10 drugs, including buprenorphine, cocaine, and MDMA. Importantly, this method maintained the fast, minimal-prep advantages that make paper spray ionization so appealing. Key takeaways:<ul><li>DLLME enhances analyte extraction from plasma, reducing matrix effects and improving quantitation.</li><li>Combining DLLME with VeriSpray maintains a low-complexity, high-speed workflow.</li></ul><h3>Conclusion: a new frontier for forensic and clinical toxicology</h3>The data shared at this workshop underscores the transformational potential of VeriSpray PaperSpray MS. Whether it’s detecting drugs in plasma for emergency toxicology, enhancing substrate performance, or integrating clever microextraction steps, researchers at KCL are proving that simplified workflows can still deliver high sensitivity and accuracy. As toxicology labs continue to face growing backlogs and limited resources, adopting a faster path to MS analysis with VeriSpray could dramatically change how drugs of abuse are detected and quantified, getting results faster, cutting costs, and ultimately supporting better outcomes in both forensic and clinical environments.<h3>Resources:</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://thermofishermarcom.app.box.com/s/gmmhe84v1x9el0fqmh695uszk936iei6">Watch the full workshop on Box- 2025 Seized Drugs Symposium Workshop and the tag is Toxicology</a></li><li>Explore the <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/labrulez-bucket-strapi-h3hsga3/br_65405_verispray_paperspray_ion_source_br65405_en_756e8e3ec9.pdf">VeriSpray product brochure</a></li><li>Case study – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_002678_lsms_clinical_verispray_toxicology_cs002678_na_en_a6096123ef.pdf">Paper spray mass spectrometry simplifies and expedites turnaround of drug toxicity screening King’s College London aims to investigate its use in emergency department applications</a></li><li>Case study – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_000866_ms_verispray_vancouver_island_univ_cs000866_en_0f5ecbd835.pdf">How paper spray mass spectrometry facilitated harm reduction drug checking</a></li><li>Past blogs in this toxicology series<ul><li>Sample prep – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6189">Sample Preparation Strategies Demystified: Choosing the Right Fit for Your Toxicology Workflow</a></li><li>Tox Explorer – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6587">Beyond Blood: Sheffield Teaching Hospitals NHS Foundation Trust Develops HRAM-Powered Method for Post-Mortem Toxicology Analysis</a></li></ul></li><li>Stay tuned to register for next years symposium at <a target="_blank" rel="noopener noreferrer" href="http://www.forensicsymposium.org">www.forensicsymposium.org</a></li><li>Check out our <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/forensics/forensic-toxicology/drug-screening-confirmation.html">drug screening and confirmation webpage</a></li></ul>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#PSMS #VeriSpray #PaperSprayMS #Toxicology<blockquote><h5>Ema Ruzic</h5>Vertical Marketing Manager, Chromatography and Mass Spectrometry Division (CMD)</blockquote>

Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry

Automated Mag-Net Enrichment Unlocks Deep and Cost-Effective LC–MS Plasma Proteomics

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/">ISC 2026</a></h3>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314">International Symposium on Chromatography (ISC)</a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.<h3>ISC 2026 SYMPOSIUM KEY DATES</h3><h4>6-10 SEPTEMBER 2026</h4><ul><li>15 January 2026: Opening of Early-bird Registration &amp; Abstract submission</li><li>11 March 2026: Deadline for abstract submission (orals)</li><li>21 April 2026: Sending acceptance letters (orals)</li><li>15 May 2026: Deadline of early-bird registration and payment &amp; Author registration deadline (orals)</li><li>1 June 2026: Preliminary detailed program on web</li><li>1 June 2026: Deadline for abstract submission (posters)</li><li>16 June 2026: Sending acceptance letters (posters)<ul><li>Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.</li></ul></li><li>30 June 2026: Author registration deadline (posters)</li><li>30 July 2026: Deadline for abstract submission (late-breaking posters)<ul><li>without the possibility of competing for the Best Poster Award</li></ul></li><li>11 August 2026: Sending acceptance letters (late-breaking posters)</li><li>18 August 2026: Author registration deadline (late-breaking posters)</li><li>25 August 2026: Deadline for late registration &amp; payment&nbsp;</li><li>6-10 September 2026: Symposium</li></ul><h3>REGISTRATION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Register HERE for the ISC 2026</a></blockquote><h3>ABSTRACT SUBMISSION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Submit your Abstract HERE</a></blockquote><h3>SCIENTIFIC PROGRAM</h3><h4>SHORT COURSES</h4><h5>SC 5 Oligonucleotides and Other Biopharmaceuticals</h5>🗓️ SUNDAY, 6 SEPTEMBER 2026🕗 12:30 – 15:45Analysis of nucleic acid and protein-based pharmaceuticalsThe pharmaceutical industry has undergone a profound transformation over the past four decades driven by continuous innovation in therapeutic and prophylactic modalities. While small molecules have been the foundation of medicine for ages, successive waves have introduced biologics such as recombinant proteins and antibodies, in addition to nucleic acid and cell-based products. Each wave has expanded our ability to treat diseases but also challenged us, analytical scientists, to build a toolbox to characterize these ever more complex modalities. This short course will cover chromatographic and mass spectrometric methods for analyzing nucleic acid and protein-based medicines including antisense oligonucleotides (ASOs), small interfering ribonucleic acid (siRNA) and larger nucleic acids such as messenger RNA (mRNA), in addition to monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs) and &nbsp;antibody-oligonucleotide conjugates (AOCs).&nbsp;<h4>Lecturers</h4><h5>Koen Sandra</h5><ul><li>Koen Sandra received a PhD degree in Biochemistry from the Ghent University, Belgium in 2005. After his PhD, he joined Pronota, a molecular diagnostics company where he was active in developing analytical platforms for disease biomarker discovery and in setting up external collaborations. In 2008, he joined RIC, a company that provides analytical support to the chemical, life sciences and pharmaceutical industries, where he holds the position of CEO. As a non-academic scientist, Koen Sandra is author of over 50 highly cited scientific papers and has presented his work at numerous conferences as an invited speaker.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_2026_Koen_Sandra_2ff9f97b34.jpg" alt="ISC 2026: Koen Sandra" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_2026_Koen_Sandra_2ff9f97b34.jpg 156w," sizes="100vw" width="500" height="500"><h5>Amanda Guiraldelli Mahr</h5><ul><li>Amanda Guiraldelli Mahr is a senior scientist at the RIC group in Belgium, specialized in chromatographic and LC-MS strategies for biopharmaceutical and small molecule analysis. With more than 17 years of experience in analytical development, she leads the design and qualification of procedures for release testing, stability studies, and structural characterization of monoclonal antibodies, peptides, and oligonucleotides, with strong expertise in SEC, IEX, RPLC, HILIC, HIC, and high-resolution MS workflows. She drives the implementation of ICH Q2(R2), Q14, and Analytical Quality by Design (AQbD) principles in collaboration with global biopharmaceutical partners. Amanda serves as a member of the United States Pharmacopeia (USP) Pharmaceutical Analytical Lifecycle and Data Science Expert Committee and is a board member of the ECA Analytical Quality Control Group. Before joining RIC, she spent more than 12 years at USP, where she worked both as a Senior Scientist – leading method development and validation projects, impurity analysis by LC-MS/GC-MS, and reference standards characterization by LC-HRMS – and as a Scientific Affairs Manager, contributing to major standards such as &lt;1220&gt; and &lt;1225&gt; and driving initiatives in AQbD, predictive modeling, and analytical procedure lifecycle management. She holds a bachelor’s degree in Pharmacy–Biochemistry and a Ph.D. in Analytical Chemistry, and has been a visiting scientist at TU Berlin and Leiden University, focusing on LC-HRMS-based protein analysis.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_2026_Amanda_Guiraldelli_Mahr_0bd046c778.jpg" alt="ISC 2026: Amanda Guiraldelli Mahr" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_2026_Amanda_Guiraldelli_Mahr_0bd046c778.jpg 156w," sizes="100vw" width="500" height="500">

ISC 2026 Short Course 5 - Oligonucleotides and Other Biopharmaceuticals

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

ALS Czech Republic

Technology Networks

Bruker

Phenomenex

SCIEX

Waters Corporation

PhenoAcademy Webinars
 Liquid Chromatography Series
<h4>HPLC Troubleshooting</h4>
<ul>
<li>Learn how to prevent and minimize your LC problems before they occur</li>
<li>Understand how to approach problem solving and troubleshooting in a logical way, including: diagnose cause and possible solutions</li>
<li>Review peak shape, and column performance problems</li>
</ul>
<blockquote>
Presenter: Kevin Zhao (Senior Technical Specialist)
</blockquote>
<blockquote>
Kevin Zhao is the Senior Technical Specialist with Phenomenex and has 5 years of experience in biochemistry research; 4 years of Protein/Cancer research with CSULA-City of Hope Cancer Collaborative and over 9 years in Phenomenex. Mr. Zhao is a member of a global Technical Support Team which includes providing problem-solving, troubleshooting, and applications assistance for customers worldwide in the fields of chromatography (liquid and gas) and sample preparation, and also handling Industries supported include – pharmaceutical and biopharmaceutical, clinical research and clinical toxicology, food safety, environmental, fuels and specialty chemicals. Mr. Zhao received his B.S. in Biology at the California State Polytechnic University, Pomona. earned his M.S. in Biochemistry at California State University, Los Angeles, and also earned a MBA at the University of the Incarnate Word.
</blockquote>
<blockquote>
Presenter: Koen Askamp (Technical Specialist)
</blockquote>
<blockquote>
Koen is from the Netherlands, studied Molecular Life Sciences at Wageningen University (Netherlands), majoring in immunology. Analytical Chemistry was one of my favorite courses – who doesn’t love solving puzzles?
</blockquote>
<blockquote>
I like drumming, scuba diving, motorcycle-riding, and this past winter I learned how to ski (a little)!
</blockquote>
<blockquote>
Presenter: Namrata Saxena (Technical Manager)
</blockquote>
<blockquote>
Namrata Saxena is a Technical Manager - Asia/Pacific” with Phenomenex and is based in Sydney, Australia. She has a post graduate degree with a specialization in Analytical Chemistry, with extensive experience in the Liquid chromatography domain, and her current focus is in Omics and Biologics field. 
</blockquote>
<blockquote>
Before joining Phenomenex she had worked as “Product Specialist” and spent several years in column chemistry, column manufacturing and method development in the application and manufacturing labs of Bischoff Chromatography, Germany. 
</blockquote>
<blockquote>
In her current role, she provides product selection, method development, training and troubleshooting support to customers as well as Phenomenex Sales Consultants globally. 
</blockquote>

Phenomenex: PhenoAcademy Webinars - Liquid Chromatography Series

HPLC Troubleshooting

Learn how to prevent and minimize your LC problems before they occur.

<h4>EU Live Interactive Web Series</h4>
Gather on Thursday or Friday at 11 AM or 12 PM CET for our live interactive web series.
Join us for an engaging journey into the world of advanced molecular analysis with our EU Live Interactive Web Series, hosted by Waters | Wyatt Technology! Dive deep into the intricacies of SEC-MALS and FFF-MALS systems, enhance your skills in ASTRA and DYNAMICS data processing, and master the measurement of dn/dc values—crucial for your research.
We dedicate 60 minutes to explore a specific topic, accompanied by a live discussion where all your questions are welcome. Whether you&#39;re dealing with polydisperse samples, eager to optimize your error analysis techniques, or curious about batch MALS work, our sessions are designed to elevate your expertise.
What&#39;s more, you’ll learn how to achieve stable RI baselines and utilize ASTRA&#39;s robust distribution analysis and results fitting features. Our web series is an invaluable, free resource exclusively for Wyatt customers, promising a 100% live, interactive learning experience.
Don’t miss out on this opportunity to connect, learn, and grow.
The live interactive web series are 100% live sessions, with anonymous Q&amp;A welcome during and after the discussion. Free for all Wyatt customers.
The EU live interactive web series are held on select Thursday or Friday afternoons at 11 AM or 12 PM CET.
May 3rd at 11:00 AM : MALS
<ul>
<li>How MALS can characterize molar mass, radius and A2?</li>
<li>How does a DAWN detector work?</li>
</ul>
May 17th at 11:00 AM : SEC-MALS
<ul>
<li>Applications and data interpretation</li>
<li>Data analysis in ASTRA</li>
</ul>
June 7th at 11:00 AM : RI &amp; dn/dc
<ul>
<li>A perfect match: MALS and RI</li>
<li>The importance of dn/dc and how to determine it</li>
</ul>
June 21st at 11:00 AM : DLS 
<ul>
<li>Benefits of measuring the Hydrodynamic Radius (Rh)</li>
<li>Dynamic Light Scattering in cuvette, high throughput and online</li>
</ul>
July 5th at 11:00 AM : Dynamics data processing tips &amp; tricks
<ul>
<li>Data interpretation and data filter</li>
<li>Use your Dyna Pro instrument to get: colloidal stability (kD/A2), thermal stability, viscosity or particle concentration</li>
</ul>
<blockquote>
Presenter: Dr. Christian Ackerschott
</blockquote>
<blockquote>
Dr. Christian Ackerschott studied Chemistry at the University of Cologne and finished with his diploma thesis in Biochemistry. He completed his studies with the PhD thesis “Characterization of Recombinant Flagelliform Spider Silk Proteins” at the Technische Universität München, where AF4-MALS was used as an essential characterization method.
</blockquote>
<blockquote>
Since 2007, Christian works at Wyatt Technology as Application Scientist and is now Head of Customer Service. His tasks also include customer trainings in Dernbach and onsite as well as education and training of the local Field Application Scientists.
</blockquote>

Waters Corporation: EU Live Interactive Web Series

RI & dn/dc

A perfect match: MALS and RI. The importance of dn/dc and how to determine it.

AAVs are attractive vehicles for targeted drug delivery. There are numerous Critical Quality Attributes (CQAs) evaluated to ensure safety and efficacy of AAVs. Aggregation is a CQA and should be controlled as AAVs are prone to aggregation from freeze thaw cycles during storage.
<ul>
<li>In this webinar, we will explore CQAs using a novel size exclusion column optimal for AAV analysis, which enables the separation of AAV monomer from aggregate species with excellent peak shape, resolution and peak profile to provide better data quality. Due to both the inert surface chemistry and flow-path in the BiozenTM dSEC-7 column, the analysis conditions were independent of the serotype showcasing the utilization of platform methodology.</li>
<li>In addition to calculating the aggregation level, aggregate molar mass, molar masses of protein and nucleic acid, and extinction coefficients of capsid and DNA were also determined. The novel particle chemistry of Biozen dSEC-7 provides instant stabilization of sensitive detectors like MALS to provide quality data.</li>
<li>Additionally, Full-to-Empty capsid ratio was determined to accurately predict capsid load demonstrating Biozen dSEC-7’s utility as a holistic solution for the determination of CQAs of AAVs.</li>
</ul>
Key Learning Points:
<ul>
<li>Learn how to optimize AAV aggregate analysis.</li>
<li>Understand how size exclusion can be effectively utilized for capsid load quantification.</li>
<li>Find out how optimized column specifications can improve data quality to determine critical quality attributes</li>
</ul>
Who should attend?
Any scientist, associate or manager that optimizes AAV aggregate analysis methods.
<blockquote>
Presenter: Claire Butré, PhD, (R&amp;D Technical Leader, Quality Assistance &amp; Ramkumar Dhandapani, PhD, Senior Product Management, Phenomenex)
</blockquote>

Phenomenex: Evaluation of AAV Aggregation & Capsid Load (Empty / Full) CQAs

Evaluation of AAV Aggregation & Capsid Load (Empty / Full) CQAs

Explore CQAs using a novel SEC column for AAV analysis, which enables the separation of AAV monomer from aggregate species.

Evaluation of AAV Aggregation & Capsid Load CQAs

In this webinar you will discover how extractables and leachables (E&amp;L) testing can be streamlined using acquisition modes enhanced by QTRAP technology. If you are new to E&amp;L testing or want to learn how your own workflows can be improved when using nominal mass technology then this webinar is for you.
Key topics that will be covered in this webinar include:
<ul>
<li>Introduction to E&amp;L analysis using nominal mass instrumentation</li>
<li>How the QTRAP can enhance E&amp;L analysis</li>
<li>The importance of libraries and how they can be implemented to improve compound identification</li>
</ul>
<blockquote>
Presenter: Ferran Sanchez (Market Development Manager, Pharma/CRO (MS &amp; CE), EMEAI, SCIEX)
</blockquote>
<blockquote>
Ferran obtained his PhD in Pharmaceutical Sciences at the University of Barcelona in 2005 and has been involved with mass spectrometry ever since. He has worked for SCIEX for 18 years holding different positions in sales, marketing and business development covering the EMEAI region. During this time, Ferran has been working closely with customers in the pharmaceutical industry to deepen his understanding of the market and user needs for delivering the right solutions at the right time.
</blockquote>
<blockquote>
Presenter: Jack Steed, Sr. (Technical Specialist, SCIEX)
</blockquote>
<blockquote>
Jack joined SCIEX in 2019 as a technical specialist, his main responsibilities include the creation and proliferation of technical marketing content such as application notes and presentations as well as having a strong focus on the pharma market and small molecule analysis. Prior to joining SCIEX, Jack was employed by a CRO working mainly in small molecule method development and validation, with an emphasis on LC and LC-MS analysis.
</blockquote>

SCIEX: Extractables and leachables: the complete workflow using QTRAP LC-MS/MS technology

Extractables and leachables: the complete workflow using QTRAP LC-MS/MS technology

Discover how extractables and leachables (E&L) testing can be streamlined using acquisition modes enhanced by QTRAP technology.

Extractables and leachables: QTRAP LC-MS/MS workflow

Limited understanding due to its complex pathophysiology and lack of definitive biomarkers currently constrains the diagnosis and treatment of Alzheimer’s disease (AD). But new research is uncovering dynamic brain changes during Alzheimer’s progression, offering potential therapeutic targets. This webinar explores how proteomics and systems biology can be integrated to elucidate AD pathology.
You’ll learn how mass spectrometry-based proteomics provides insights into brain changes and assists biomarker discovery in cerebrospinal fluid and plasma, and discover the potential of affinity-based proteomics for reliable biomarker identification. Our expert speaker will delve into intricate networks like proteostasis and the matrisome, highlighting their implications for therapeutic development.
Attend this webinar to:
<ul>
<li>Gain insights into the landscape of AD brain changes using unbiased mass spectrometry-based proteomics</li>
<li>Learn about biomarker discovery in AD cerebrospinal fluid and plasma through multi-platform proteomic analysis</li>
<li>Understand the potential of affinity-based proteomics, including modified aptamer technology, in identifying reliable biomarkers for AD</li>
<li>Explore the intricate networks associated with AD pathology and their implications for therapeutic development</li>
</ul>
<blockquote>
Presenter: Dr. Erik Johnson (Assistant Professor, Department of Neurology, Emory University)
</blockquote>

Technology Networks: Using Proteomics To Advance Understanding of Alzheimer’s Disease

Using Proteomics To Advance Understanding of Alzheimer’s Disease

You’ll learn how mass spectrometry-based proteomics provides insights into brain changes and assists biomarker discovery in cerebrospinal fluid and plasma.

Using Proteomics To Understand Alzheimer’s Disease

MALDI Imaging allows for interrogation of the spatial distribution of metabolites and lipids in tissue, as well as expanding targeted analysis to small molecules, glycans, and targeted proteins. Recent technical developments enable imaging for maximum biological information at robust (sub)cellular resolution. However, imaging entire tissue sections with high spatial resolution entails large number of pixels and requires extensive acquisition times. Thus, researchers are seeking for alternative high-speed chemical imaging techniques, which are conducted prior to MALDI Imaging to narrow down the regions of interest (ROIs) on large sample areas. Infrared Laser Imaging (ILIM) allows non-destructive, label free biochemical imaging of complete tissue sections within minutes – thus represents the ideal complementary analytical tool to make MALDI Imaging faster and smarter.
Webinar Overview
This webinar will introduce how breakthrough IR Laser Imaging performance is combined with best-in-class MALDI Imaging. Bruker’s new end-to-end workflow for IR Guided MALDI Imaging enhances sample throughput and provides increased analytical depth by offering maximized spatial resolution and collision cross section (CCS)-enabled label analysis for large-scale MALDI Imaging studies in biological and pharmaceutical research.
What to Expect:
Live presentation from Bruker’s experts to see the how tissue imaging has become faster than ever, the seamless integration of Infrared Laser Imaging (ILIM) into existing MALDI Imaging workflows and highlighting user stories, how IR Guided MALDI Imaging paves the way for deeper spatial multiomics of complex biological systems.
Who Should Attend:
<ul>
<li>MALDI Imaging users wanting to expand their workflows for increased sample throughput and analytical depth.</li>
<li>Scientists &amp; researchers interested in conducting multimodal imaging approaches for increased biological insight.</li>
<li>Anyone interested in learning more about Infrared Laser Imaging and MALDI Imaging capabilities.</li>
</ul>
<blockquote>
Presenter: Wojciech Kazmierski ( Country Manager, Bruker Optics, Poznan, Poland)
</blockquote>
<blockquote>
Presenter: Arne Behrens, Ph.D. (Application Scientist Imaging, Bruker Daltonics, Bremen, Germany)
</blockquote>
<blockquote>
Presenter: Domenic Dreisbach (Business Development Multimodal Imaging, Bruker Optics, Ettlingen, Germany)
</blockquote>

Bruker: Make MALDI Imaging faster and smarter with Infrared Laser Imaging

Make MALDI Imaging faster and smarter with Infrared Laser Imaging

IR Laser Imaging combined with best-in-class MALDI Imaging.

MALDI Imaging with Infrared Laser Imaging

This webinar unveils the development of a high-throughput multidimensional liquid chromatography approach in combination with charged aerosol detection (CAD), leveraging a combination of ion exchange and reversed-phase columns, ensuring accurate and precise analysis within minutes.
Discover how this method advances formulation development, stability testing, and batch release, providing researchers with valuable insights into surfactant degradation dynamics. 
Learning Points: 
<ul>
<li>Discover cutting-edge techniques for rapid analysis of surfactants in antibody formulations</li>
<li>Unveil high-throughput liquid chromatography with charged aerosol detection</li>
<li>Gain valuable insights for optimizing formulation development and stability testing</li>
</ul>
Who should attend?
<ul>
<li>Biopharmaceutical scientists and researchers specializing in monoclonal antibody development</li>
<li>Analytical chemists and technicians involved in pharmaceutical formulation analysis</li>
<li>Quality control and regulatory affairs professionals in the pharmaceutical industry</li>
</ul>
<blockquote>
Presenter: Maksymilian Zegota, PhD (Senior Scientist, Coriolis Pharma)
</blockquote>
<blockquote>
Dr. Zegota earned his PH.D. in chemistry from the Max Planck Institute for polymer research in Mainz, Germany, concentrating on site-selective protein modification.
</blockquote>
<blockquote>
After completing his doctorate, he joined Coriolis Pharma in Martinsried, Germany.
</blockquote>
<blockquote>
Currently, Dr. Zegota focuses on developing Novel methods for surfactant analysis in biologics to assist in the root-cause analysis of polysorbate and poloxamer degradation, contributing to formulation development in the pharmaceutical field.
</blockquote>
<blockquote>
Presenter: Marcus Klee (Marcus Klee, Regional Marketing Manager HPLC, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Graduated in Chemical Engineering from Hochschule Fresenius in 2000, specialized in Marketing &amp; Sales. Since then, held various marketing roles since 2000, currently serving as the Regional Marketing Manager EMEA for HPLC
</blockquote>

Thermo Scientific: Advancing analytical techniques in monoclonal antibody formulations

Advancing analytical techniques in monoclonal antibody formulations

Explore cutting-edge methodology for online protein removal and characterization of polysorbates and poloxamer in monoclonal antibody formulations.

Analytical techniques in monoclonal antibody formulations

Together with ALS Czech Republic, we bring you an exclusive webinar series offering insights into the world of per- and polyfluoroalkyl substances (PFAS). The three-part series will bring together regulatory experts from REGARTIS and environmental laboratories professionals of ALS Czech Republic to address PFAS from environmental risks to the evolving regulatory landscape and analytical challenges.
First, we will explore their uses, environmental hazards, and restriction efforts. The second part will be focused on analytics, helping attendees understand PFAS testing in various matrices and the implications of their widespread environmental presence. Finally, the series will offer a discussion on regulatory processes, compliance strategies, and the technical aspects of PFAS analysis, such as sampling rules and possible matrices types. The core aim of the series is to provide chemical industry stakeholders with the knowledge to effectively manage PFAS compliance and analysis both.
<h3>Changes to regulations and restriction</h3>
<ul>
<li>Mgr. Yana Tributsyna</li>
</ul>
The first session by REGARTIS will look into restrictions of PFAS under consideration due to their adverse effects and persistence in the environment. We will also discuss the global emissions and presence of PFAS and outline the upcoming regulatory changes. These include a detailed look at already restricted PFAS, the REACH restriction process, and new proposals that could impact a broad array of PFAS compounds.
<blockquote>
Presenter: Mgr. Yana Tributsyna (Regulatory Queen, REACH manager – REGARTIS)
</blockquote>
<blockquote>
Yana graduated from Charles University in Prague, where she studied molecular biology and genetics. She is skilled in REACH registration dossier compilation and SDS/eSDS creation, she also has experience with chemical auditing and biocidal regulations. She speaks fluently Russian, Czech, and English. She is a certified REACH manager.
</blockquote>

ALS Czech Republic: PFAS: Strategic Approaches for Chemical Industry Compliance

PFAS: Strategic Approaches for Chemical Industry Compliance - Changes to regulations and restriction

Look into restrictions of PFAS under consideration due to their adverse effects and persistence in the environment.

PFAS: Changes to regulations and restriction

Overview:
Nitrosamines – the current state of play
<ul>
<li>Background.</li>
<li>Potential Sources of Nitrosamines.</li>
<li>Practical Challenges for N-Nitrosamine Analysis.</li>
<li>Sample Preparation Approach for Analysis of N-Nitrosamines in Drug Products.</li>
</ul>
Key Learning:
<ul>
<li>A New SPE Method for for Simultaneous Quantification of 13 N-Nitrosamines in Various Drug Products</li>
</ul>
<blockquote>
Presenter: Dr. Heiko Behr (Senior Business Development Manager, Phenomenex)
</blockquote>

Phenomenex: New SPE Method for Simultaneous Quantification of 13 N-Nitrosamines in Various Drug Products

New SPE Method for Simultaneous Quantification of 13 N-Nitrosamines in Various Drug Products

Sample Preparation Approach for Analysis of N-Nitrosamines in Drug Products.

New SPE Method for 13 N-Nitrosamines in Drug Products

<h4>Automating Laboratory Workflows with Andrew+ and OneLab Software: A Virtual Demonstration</h4>
We are excited to invite you to our upcoming webinar series on how to easily bring automation to your lab and transform your current workflows.
<h4>EPISODE 1 - Biomolecules Workflows</h4>
In this webinar, we’re excited to showcase Andrew+, an advanced pipetting robot, and OneLab, a workflow design execution software.
Both are game-changers in pharmaceutical workflows that utilize automation to streamline everything from drug discovery to quality control, including complex workflows such as released glycan analysis, peptide mapping, and amino acid analysis.
In this episode, you will:
<ul>
<li>Hear directly from one of our Andrew+ users in the biotech industry, who kindly agreed to make a short video interview about their experience with Andrew+ and OneLab for oligonucleotide analysis.</li>
<li>Take a tour of the user-friendly OneLab Software, showing how Andrew+ can be intuitively guided to carry out complex tasks, reducing manual labour and minimizing errors.</li>
</ul>
For example, Andrew+ and OneLab can automate sample preparation protocols for therapeutic oligonucleotide (ONT) bioanalysis that can be challenging, requiring extensive method development. Some workflows, like liquid-liquid extraction (LLE) can be difficult to automate, while others may use detergent-based reagents, requiring extensive washing and sample preparation to make it LC-MS compatible.
We’ll also talk about data management capabilities, highlighting how OneLab ensures data integrity and helps meet regulatory standards.
So, come join us for this demonstration!
Not sure to be able to attend live sessions?
Register today and watch the webinars on-demand
<h4>Other episodes rfom the series:</h4>
Transform Your Daily Lab Operations with Automation - Episode 2: Pharma workflows
<ul>
<li>Tuesday, July 09, 2024, 11:00 AM CEST</li>
</ul>
Transform Your Daily Lab Operations with Automation - Episode 3: Food and Environmental Workflows
<ul>
<li>Thursday, September 19, 2024, 11:00 AM CEST</li>
</ul>
<blockquote>
Presenter: Loïc Roux (Founder/CTO, OligoTune Ltd.)
</blockquote>
<blockquote>
Loïc Roux, PhD, Founder/CTO of OligoTune Ltd, is an accomplished large molecule scientist with a focus on nucleotide therapeutic approaches. He has worked across the globe in both healthcare and private medicine, where most recently he has partnered in the UK with Waters to set up private and public laboratories using our equipment and automation.
</blockquote>
<blockquote>
Presenter: Philip Quinn (Senior Applications Specialist Chemistry Europe, Waters Corporation)
</blockquote>
<blockquote>
Phil started his career at Waters in 2018 as an Application Support Specialist in the Chemistry Consumables group for the UK. In his current role he is responsible for commercial pre and post-sale support for Chemistry Consumables and Automation across Europe. Prior to joining Waters, Phil worked at large Pharma organisations over 10+ years and gained extensive experience in Analytical Development and QC environments, including the Development, Optimisation, Validation and Transfer of LC methodologies.
</blockquote>
<blockquote>
Presenter: Jasper Eaton (Senior Product Marketing Manager, Waters Corporation)
</blockquote>
<blockquote>
Jasper has a Bachelor’s degree in General Biology and obtained a Masters Degree in Molecular and Cellular Biology from the University of Grenoble-Alpes. He was previously the EU Sales Manager at Andrew Alliance since 2017, and is now a Senior Product Marketing Manager at Waters Corporation. His experience has made him well versed in the challenges faced by customers looking to automate their lab workflows.
</blockquote>

Waters Corporation: Transform Your Daily Lab Operations with Automation - Episode 1: Biomolecules workflows

Transform Your Daily Lab Operations with Automation - Episode 1: Biomolecules workflows

In this webinar, we’re excited to showcase Andrew+, an advanced pipetting robot, and OneLab, a workflow design execution software.