At the January 2025 CFSRE Seized Drugs Symposium, a Thermo Fisher Scientific–sponsored workshop showcased the potential of <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2240">Thermo Scientific VeriSpray PaperSpray mass spectrometry </a>(PS-MS) to transform drug analysis workflows in both forensic and clinical toxicology. Three researchers from King’s College London (KCL)—PhD candidate Stefania Boccuzzi and MSc graduates Marwa AlJanahi and Saeed Almheiri—presented their findings on how to optimise this cutting-edge technique for faster, more sensitive, and more cost-effective detection of drugs of abuse.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_040182cb06.jpg" alt="Thermo Fisher Scientific: Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry: Thermo Fisher Scientific’s Edward Goucher and Alexandra Graham pictured beside KCL’s Stefania Boccuzzi and Vincenzo Abbate" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_040182cb06.jpg 245w," sizes="100vw" width="1024" height="512"><h3>Why VeriSpray? A simpler, faster path to results</h3>Traditional LC-MS workflows can be powerful, but when labs are overwhelmed by backlogs, the time and complexity of sample preparation and chromatography can be limiting. VeriSpray offers a remarkably simplified path to MS analysis, directly ionizing complex matrices using a paper substrate—no LC step required.<h5>Key benefits include:</h5><ul><li>&lt;2-minute results thanks to minimal sample prep and elimination of LC</li><li>Reduced cost per test by cutting solvent use and simplifying training requirements</li><li>Automation-ready with support for unattended operation of up to 240 samples</li><li>Seamless integration with Thermo Scientific triple quadrupole systems</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_2_eb1f7dacc2.jpg" alt="Thermo Fisher Scientific: Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Advancing_Drug_Analysis_with_Veri_Spray_Paper_Spray_Mass_Spectrometry_2_eb1f7dacc2.jpg 245w," sizes="100vw" width="700" height="317"><h3>Enhancing emergency toxicology with direct MS analysis</h3>In the emergency room, timely drug identification is critical, but clinicians often rely on patient self-report or symptom-based assessments. Stefania’s PhD research seeks to change that. Her team is developing a rapid, extraction-free method using VeriSpray PS-MS for the targeted analysis of plasma samples from patients presenting with acute drug toxicity.By using dried matrix spots on a paper substrate and coupling this with a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/404">Thermo Scientific TSQ Altis Plus Triple Quadrupole Mass Spectrometer</a>, Stefania’s work provides an alternative screening technique to chromatography, delivering faster, actionable results to guide early clinical decision-making.<h5>Key takeaways:</h5><ul><li>Paper spray MS is an ambient ionization technique suitable for emergency toxicology due to its rapid results and minimal sample prep.</li><li>Enhancing the paper substrate and adding microextraction steps can boost sensitivity without sacrificing speed.</li></ul><h3>Substrate matters: boosting detection with paper treatment</h3>One key limitation of PS-MS is the interference that can arise from the paper substrate itself. Marwa’s research explored nine different paper treatments, ranging from acids to solvents, to improve the signal-to-blank (S/B) ratio when analyzing eight common drugs in whole blood.The most promising results came from formic acid and nitric acid treatments, which significantly enhanced analyte detection. Although these methods are currently time-consuming, Marwa envisions future industrial-scale production of pre-treated cartridges to support scalable clinical workflows.<h5>Key takeaways:</h5><ul><li>Substrate optimization can significantly reduce background noise in PS-MS analysis.</li><li>Acid-treated paper enhances S/B ratios, enabling more reliable detection of drugs in blood.</li><li>Industrial pre-treatment could make these improvements broadly accessible.</li></ul><h3>DLLME meets paper spray: improving sensitivity in plasma</h3>Saeed Almheiri’s presentation focused on dispersive liquid-liquid microextraction (DLLME) as a sample prep technique to increase sensitivity for PS-MS analysis of drugs in plasma, without adding significant complexity to the workflow.Using DLLME prior to VeriSpray analysis, Saeed demonstrated improved detection limits (as low as 0.3 ng/mL) across a panel of 10 drugs, including buprenorphine, cocaine, and MDMA. Importantly, this method maintained the fast, minimal-prep advantages that make paper spray ionization so appealing. Key takeaways:<ul><li>DLLME enhances analyte extraction from plasma, reducing matrix effects and improving quantitation.</li><li>Combining DLLME with VeriSpray maintains a low-complexity, high-speed workflow.</li></ul><h3>Conclusion: a new frontier for forensic and clinical toxicology</h3>The data shared at this workshop underscores the transformational potential of VeriSpray PaperSpray MS. Whether it’s detecting drugs in plasma for emergency toxicology, enhancing substrate performance, or integrating clever microextraction steps, researchers at KCL are proving that simplified workflows can still deliver high sensitivity and accuracy. As toxicology labs continue to face growing backlogs and limited resources, adopting a faster path to MS analysis with VeriSpray could dramatically change how drugs of abuse are detected and quantified, getting results faster, cutting costs, and ultimately supporting better outcomes in both forensic and clinical environments.<h3>Resources:</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://thermofishermarcom.app.box.com/s/gmmhe84v1x9el0fqmh695uszk936iei6">Watch the full workshop on Box- 2025 Seized Drugs Symposium Workshop and the tag is Toxicology</a></li><li>Explore the <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/labrulez-bucket-strapi-h3hsga3/br_65405_verispray_paperspray_ion_source_br65405_en_756e8e3ec9.pdf">VeriSpray product brochure</a></li><li>Case study – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_002678_lsms_clinical_verispray_toxicology_cs002678_na_en_a6096123ef.pdf">Paper spray mass spectrometry simplifies and expedites turnaround of drug toxicity screening King’s College London aims to investigate its use in emergency department applications</a></li><li>Case study – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/cs_000866_ms_verispray_vancouver_island_univ_cs000866_en_0f5ecbd835.pdf">How paper spray mass spectrometry facilitated harm reduction drug checking</a></li><li>Past blogs in this toxicology series<ul><li>Sample prep – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6189">Sample Preparation Strategies Demystified: Choosing the Right Fit for Your Toxicology Workflow</a></li><li>Tox Explorer – <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/6587">Beyond Blood: Sheffield Teaching Hospitals NHS Foundation Trust Develops HRAM-Powered Method for Post-Mortem Toxicology Analysis</a></li></ul></li><li>Stay tuned to register for next years symposium at <a target="_blank" rel="noopener noreferrer" href="http://www.forensicsymposium.org">www.forensicsymposium.org</a></li><li>Check out our <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/forensics/forensic-toxicology/drug-screening-confirmation.html">drug screening and confirmation webpage</a></li></ul>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#PSMS #VeriSpray #PaperSprayMS #Toxicology<blockquote><h5>Ema Ruzic</h5>Vertical Marketing Manager, Chromatography and Mass Spectrometry Division (CMD)</blockquote>

Advancing Drug Analysis with VeriSpray PaperSpray Mass Spectrometry

Automated Mag-Net Enrichment Unlocks Deep and Cost-Effective LC–MS Plasma Proteomics

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/">ISC 2026</a></h3>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314">International Symposium on Chromatography (ISC)</a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.<h3>ISC 2026 SYMPOSIUM KEY DATES</h3><h4>6-10 SEPTEMBER 2026</h4><ul><li>15 January 2026: Opening of Early-bird Registration &amp; Abstract submission</li><li>11 March 2026: Deadline for abstract submission (orals)</li><li>21 April 2026: Sending acceptance letters (orals)</li><li>15 May 2026: Deadline of early-bird registration and payment &amp; Author registration deadline (orals)</li><li>1 June 2026: Preliminary detailed program on web</li><li>1 June 2026: Deadline for abstract submission (posters)</li><li>16 June 2026: Sending acceptance letters (posters)<ul><li>Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.</li></ul></li><li>30 June 2026: Author registration deadline (posters)</li><li>30 July 2026: Deadline for abstract submission (late-breaking posters)<ul><li>without the possibility of competing for the Best Poster Award</li></ul></li><li>11 August 2026: Sending acceptance letters (late-breaking posters)</li><li>18 August 2026: Author registration deadline (late-breaking posters)</li><li>25 August 2026: Deadline for late registration &amp; payment&nbsp;</li><li>6-10 September 2026: Symposium</li></ul><h3>REGISTRATION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Register HERE for the ISC 2026</a></blockquote><h3>ABSTRACT SUBMISSION</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Submit your Abstract HERE</a></blockquote><h3>SCIENTIFIC PROGRAM</h3><h4>SHORT COURSES</h4><h5>SC 5 Oligonucleotides and Other Biopharmaceuticals</h5>🗓️ SUNDAY, 6 SEPTEMBER 2026🕗 12:30 – 15:45Analysis of nucleic acid and protein-based pharmaceuticalsThe pharmaceutical industry has undergone a profound transformation over the past four decades driven by continuous innovation in therapeutic and prophylactic modalities. While small molecules have been the foundation of medicine for ages, successive waves have introduced biologics such as recombinant proteins and antibodies, in addition to nucleic acid and cell-based products. Each wave has expanded our ability to treat diseases but also challenged us, analytical scientists, to build a toolbox to characterize these ever more complex modalities. This short course will cover chromatographic and mass spectrometric methods for analyzing nucleic acid and protein-based medicines including antisense oligonucleotides (ASOs), small interfering ribonucleic acid (siRNA) and larger nucleic acids such as messenger RNA (mRNA), in addition to monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs) and &nbsp;antibody-oligonucleotide conjugates (AOCs).&nbsp;<h4>Lecturers</h4><h5>Koen Sandra</h5><ul><li>Koen Sandra received a PhD degree in Biochemistry from the Ghent University, Belgium in 2005. After his PhD, he joined Pronota, a molecular diagnostics company where he was active in developing analytical platforms for disease biomarker discovery and in setting up external collaborations. In 2008, he joined RIC, a company that provides analytical support to the chemical, life sciences and pharmaceutical industries, where he holds the position of CEO. As a non-academic scientist, Koen Sandra is author of over 50 highly cited scientific papers and has presented his work at numerous conferences as an invited speaker.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_2026_Koen_Sandra_2ff9f97b34.jpg" alt="ISC 2026: Koen Sandra" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_2026_Koen_Sandra_2ff9f97b34.jpg 156w," sizes="100vw" width="500" height="500"><h5>Amanda Guiraldelli Mahr</h5><ul><li>Amanda Guiraldelli Mahr is a senior scientist at the RIC group in Belgium, specialized in chromatographic and LC-MS strategies for biopharmaceutical and small molecule analysis. With more than 17 years of experience in analytical development, she leads the design and qualification of procedures for release testing, stability studies, and structural characterization of monoclonal antibodies, peptides, and oligonucleotides, with strong expertise in SEC, IEX, RPLC, HILIC, HIC, and high-resolution MS workflows. She drives the implementation of ICH Q2(R2), Q14, and Analytical Quality by Design (AQbD) principles in collaboration with global biopharmaceutical partners. Amanda serves as a member of the United States Pharmacopeia (USP) Pharmaceutical Analytical Lifecycle and Data Science Expert Committee and is a board member of the ECA Analytical Quality Control Group. Before joining RIC, she spent more than 12 years at USP, where she worked both as a Senior Scientist – leading method development and validation projects, impurity analysis by LC-MS/GC-MS, and reference standards characterization by LC-HRMS – and as a Scientific Affairs Manager, contributing to major standards such as &lt;1220&gt; and &lt;1225&gt; and driving initiatives in AQbD, predictive modeling, and analytical procedure lifecycle management. She holds a bachelor’s degree in Pharmacy–Biochemistry and a Ph.D. in Analytical Chemistry, and has been a visiting scientist at TU Berlin and Leiden University, focusing on LC-HRMS-based protein analysis.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_2026_Amanda_Guiraldelli_Mahr_0bd046c778.jpg" alt="ISC 2026: Amanda Guiraldelli Mahr" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_2026_Amanda_Guiraldelli_Mahr_0bd046c778.jpg 156w," sizes="100vw" width="500" height="500">

ISC 2026 Short Course 5 - Oligonucleotides and Other Biopharmaceuticals

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Mettler-Toledo

Agilent Technologies

Technology Networks

SelectScience

C&EN

Waters Corporation

<h3>Solving Problems That Matter - a Waters webinar series featuring USP speakers</h3>
<h4>Episode 3: Enhanced Method Development</h4>
Summary
Enhanced method development is a science and risk-based approach to analytical procedure development that leverages QbD principles and “starts with the end in mind”. Our panelists Amanda Guiraldelli from the USP and Richard Verseput form S-Matrix will share their insights on approaches outlined in the ICH Q14 quality guidelines and USP general chapter &lt;1220&gt;. 
Key learning objectives:
<ul>
<li>Discover the benefits of the enhanced method development approach</li>
<li>Learn how to implement analytical QbD approaches in your lab</li>
</ul>
Who should attend:
Pharma scientists involved with analytical LC method development
<blockquote>
Presenter: Amanda Guiraldelli, Ph.D. (Scientific Affairs Manager, U.S. Pharmacopoeia)
</blockquote>
<blockquote>
Amanda Guiraldelli has been with USP since 2012 and holds the position of scientific affairs manager and principle scientist in the compendial science group-general chapters. She also serves as scientific liaison for the USP Measurement and Data Quality Expert Committee, where she works to develop and revise USP standards related to analytical procedure lifecycle/validation. Previously, Amanda worked as senior scientist at the USP reference standard laboratory for 8 years with characterization of compendial standards. She is visiting professor at the Institute of Chemistry at the University of Campinas (UNICAMP) in Brazil and is a frequent speaker and instructor on topics related to analytical procedure life cycle, Analytical Quality by Design (AQbD) and Chromatography. Amanda is specialist in mass spectrometry, chromatography, omics and chemometrics and has more than 15 years of experience in pharmaceutical R&amp;D areas. Prior to joining USP, she was R&amp;D scientist in a brazilian pharmaceutical industry and visiting scientist at TU Berlin in Germany and Leiden University in Netherlands (Center for Proteomics and Metabolomics) working on proteins characterization by LC-HRMS and procedure development using UHPLC-HRMS. Amanda is graduated in pharmacy biochemistry and holds a Ph.D. in analytical chemistry from the FCFRP - University of São Paulo (metabolomics by UHPLC-HRMS, GC-MS and 1H NMR and chemometrics).
</blockquote>
<blockquote>
Presenter: Richard Verseput (President, S-Matrix)
</blockquote>
<blockquote>
Richard Verseput has over 30 years of experience applying QbD tools and methods in multiple industries. For the last 18 years he has worked with analytical instrument manufacturers, regulatory agencies, and global pharma customers to develop and advance automated QbD experimentation. Richard Verseput is currently president of S-Matrix – the developer of Fusion QbD® – a regulatory compliance supporting software platform which automates QbD experimentation, peak tracking, and chromatography data modeling for the successful development, validation, and transfer of LC and LC-MS methods.
</blockquote>
<blockquote>
Moderated by: Isabelle Vu Trieu (Pharmaceutical Market Development Manager, Americas, Waters Corporation)
</blockquote>
<blockquote>
Isabelle is a business development professional dedicated to delivering benefits to analytical scientists in the life sciences industry. With over 20 years of experience in providing chromatography and mass spectrometry solutions, Isabelle is particularly interested in helping pharmaceutical scientists achieve the data quality and integrity needed to drive decisions for drug quality, safety and efficacy. Isabelle joined Waters in 2009 and currently manages the development of the pharmaceutical market in the Americas. She holds Masters’ degrees in Chemistry from Columbia University and the University Claude Bernard in Lyon, France as well as a Chemical Engineering degree from Ecole Supérieure de Chimie Physique Electronique in Lyon, France.
</blockquote>

Waters Corporation: Solving Problems That Matter - a Waters webinar series featuring USP speakers

Enhanced Method Development

Solving Problems That Matter - a Waters webinar series featuring USP speakers. Episode 3: Enhanced Method Development.

Synthetic and naturally occurring macromolecules are often complex mixtures of many molecules differing in molar mass, as well as in other structural features such as comonomer content and distribution, branching, or end-group functionalization. One-dimensional separation methods like size exclusion chromatography (SEC) or interaction chromatography (IC) are usually not sufficient to resolve such complex mixtures due to limitations of the separation mechanisms. Given the multidimensional complexity of such samples, hyphenated separation methods are increasingly applied for their characterization.
In a 2D-LC separation, separation is first achieved by one feature (e.g. comonomer content) followed by a second separation by another property, such as size. This allows determination of the correlation between different structural features such as the dependence of chemical composition on molar mass.
In this webinar, our speakers will present the concept, different approaches for technical realization, and industrial applications of 2D-LC in polymer separations.
Key learning objectives
<ul>
<li>Explore the multidimensional heterogeneity of polymers</li>
<li>Learn how to perform 2D-LC separations of polymers</li>
<li>Discover additional information that can be gained by 2D-LC separations</li>
</ul>
Who should attend?
<ul>
<li>Polymer researchers</li>
<li>Scientists interested in polymer and macromolecular analysis,</li>
<li>Material scientists</li>
<li>Scientists and practitioners involved in complex separation problems</li>
</ul>
<h4>View other webinars in this series here:</h4>
Part 1: <a href="https://lcms.labrulez.com/webinar/3690">Unraveling the Intricacies of Size Exclusion Chromatography – Strength and Limitations</a>
Part 2: <a href="https://lcms.labrulez.com/webinar/3691">Detection in Gel Permeation Chromatography /Size Exclusion Chromatography</a>
Part 3: <a href="https://lcms.labrulez.com/webinar/3693">Characterization of Macromolecules by SEC-Light Scattering</a>
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
<blockquote>
Presenter: Dr. Wolfgang Radke (Head of Contract Analysis, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Dr. Wolfgang Radke obtained his PhD in Chemistry from the University of Mainz, Germany. He has over 30 years of experience in the field of polymer chromatography. He has significant knowledge in size exclusion chromatography, gel permeation chromatography (SEC/GPC) with conventional, MALS, and viscometry detectors . He is also experienced in polymer separations using interaction chromatography and two-dimensional chromatography. He is currently the head of the contract analysis group at Agilent Technologies.
</blockquote>
<blockquote>
Presenter: Dr. Mubasher Ahmed Bashir (Research Scientist, Dow Inc.)
</blockquote>
<blockquote>
Dr. Mubasher Bashir obtained his PhD in Chemistry from the German Institute of Plastics, DKI at TU Darmstadt, Germany. He is a research scientist and the global polymer separations technology network leader in analytical science, Core R&amp;D, at the Dow Chemical Company. He has more than 16 years of experience in analytical research and applications in the chemical industry. His current work focuses on characterizing complex polymers by employing various separation techniques (AF4, SEC, 2D-LC) and advanced detection with the goal of establishing structure property relationships to facilitate new product and process development.
</blockquote>
<blockquote>
Presenter: Jemima Arnold (Editorial Assistant, SelectScience)
</blockquote>
<blockquote>
Jemima studied Cellular and Molecular Medicine at the University of Bristol, UK, and as a member of the Editorial team, she now plays an integral role in shaping the content on SelectScience.
</blockquote>

SelectScience: Concepts, Challenges and Applications for 2D-LC of Polymers

Concepts, Challenges and Applications for 2D-LC of Polymers

The concept, different approaches for technical realization, and industrial applications of 2D-LC in polymer separations.

When reconstructing and analyzing the tumor–immune microenvironment (TIME), exploring the spatial context of the tumor at single-cell resolution can bring new insights into the cell–cell or cell–extracellular matrix interactions.
Mapping the TIME in three dimensions offers researchers the opportunity to probe deeper into spatial cell heterogeneity in tumors and understand the impact of the TIME on cancer growth and evolution.
Join this webinar to discover how to integrate spatial biology and multiomics approaches to reveal the intricate interactions between cancer cells and their environment.
Attend this webinar to:
<ul>
<li>Learn how to gain multidimensional spatial information for disease-based research</li>
<li>Discover the impact of detecting molecular and metabolic changes in cancer cells </li>
<li>Understand the utility of mass spectrometry in assessing novel predictive biomarkers in cellular phenotypes</li>
</ul>
<blockquote>
Presenter: Professor Jared Burks (Professor/Co-Director, Flow Cytometry &amp; Cellular Imaging Core Facility, M.D. Anderson Cancer Center)
</blockquote>

Technology Networks: Multiplex Multiomics: The Future of Spatial Biology in Cancer Research

Multiplex Multiomics: The Future of Spatial Biology in Cancer Research

Discover how to integrate spatial biology and multiomics approaches to reveal the intricate interactions between cancer cells and their environment.

Multiplex Multiomics: Spatial Biology in Cancer Research

We want to Help you gain the advantages from advanced automated electrophoresis solutions. Solutions that you’ll need to accelerate your next-generation sequencing projects, cell-free DNA and genomic DNA analysis, RNA and proteins quality controls.
Does your lab need a Tech Upgrade? A technology upgrade may help you save time and money. During the workshop, you’ll hear the benefits your lab can get if you upgrade.
Come to the Workshop to:
<ul>
<li>Learn how the Advanced AE platforms perform in terms of hardware, software, and assays as well as workflows.</li>
<li>See equivalent data between the Bioanalyzer, TapeStation, and Fragment Analyzer system.</li>
<li>Discover the key advantages and benefits of the advanced platforms.</li>
<li>Listen to a customer experience.</li>
</ul>
<blockquote>
Presenter: Dr. Matthias Meister (Product Manager, Agilent Technologies Germany)
</blockquote>
<blockquote>
Matthias Meister is Product Manager at Agilent for the Bioanalyzer portfolio. He joined the marketing team for Automated Electrophoresis in 2022 and is based in Waldbronn, Germany. Prior to joining Agilent, he worked as a postdoctoral researcher at the German Cancer Research Center (DKFZ) in Heidelberg, where he also received his PhD.
</blockquote>
<blockquote>
Presenter: Sébastien Boulanger (Scientific Expert, Institute of Pathology and Genetics (IPG), Belgium)
</blockquote>
<blockquote>
Sébastien Boulanger integrated the Institute of Pathology and Genetics (IPG) of Gosselies as a lab technician in the molecular biology department in 1999. IPG is one of the eight Genetics Centers recognized in Belgium.
</blockquote>
<blockquote>
He gradually moved to a more scientific position and currently recognized by the Belgian society of Human Genetics as a Medical Genetics Laboratory Expert being now one of the main responsible of the technical lab development.
</blockquote>

Agilent: Upgrade your Tech with Agilent Advanced Automated Electrophoresis Solutions

Upgrade your Tech with Agilent Advanced Automated Electrophoresis Solutions

We want to help you gain the advantages from advanced automated electrophoresis solutions.

Agilent Advanced Automated Electrophoresis Solutions

In this webinar, Dr. Zijie “Beryl” Xia will provide a sneak peek inside the non-commercial, research driven PFAS testing lab at Claros Technologies. 
Beryl’s lab focuses on supporting the research and development of PFAS remediation and destruction at Claros Technologies, and has encountered some interesting problems, while learning some fun facts about PFAS in the process. 
Data from various methods on Waters Xevo TQ-Absolute will be shared, including both the standard methods and some customized approaches. The goal for this webinar is to share her experiences and knowledge about PFAS with the community.
For more information please contact Jenifer_Lewis@Waters.com or narendra_meruva@Waters.com
<blockquote>
Presenter: Dr. Zijie “Beryl” Xia (Director of the Analytical Laboratory and Service, Claros Technologies)
</blockquote>
<blockquote>
Dr. Zijie “Beryl” Xia obtained her Ph.D. in chemistry from University of California, Berkeley, with a focus in analytical and physical chemistry, especially in the field of mass spectrometry. She currently serves as the Director of the Analytical Laboratory and Service at Claros Technologies, offering both standard PFAS analysis as well as customized method development for non-standard compounds and diverse matrices, including non-potable water and textiles. Dr. Xia is an industry leader in PFAS analysis and is an active member of the ASTM International committee for PFAS method development.
</blockquote>
<blockquote>
Moderator: Jenifer Lewis (Senior Environmental Market Development Manager, Waters Corporation)
</blockquote>
<blockquote>
Jenifer Lewis is a Senior Market Development Manager with Waters Corp, focusing on theenvironmental market. She supports Waters’ business development teams in the Americas region,bringing over 30 years of experience in the environmental industry to assist with our customer’schallenges and needs. She has a bachelor’s degree in chemistry and an extensive background in GCand LC applications.
</blockquote>

Waters Corporation: Learnings from An Atypical PFAS Testing Lab

Learnings from An Atypical PFAS Testing Lab

In this webinar, Dr. Zijie “Beryl” Xia will provide a sneak peek inside the non-commercial, research driven PFAS testing lab at Claros Technologies. 

Improving Process Performance
Event Program
<ul>
<li>The value of in-line measurement of quality-relevant analytical parameters</li>
<li>How a new pH sensor improves brewery processes</li>
<li>The importance of precise recognition of phase changes</li>
<li>How to ensure accuracy of dissolved oxygen sensors</li>
</ul>
Greater Confidence in Your Processes.
In-line measurement of quality-related analytics supplement process control with important information. 
In this webinar, we will show how the in-line measurement of relevant parameters helps to drive processes closer to their optimum.
One focus will be on the in-line measurement of pH and we will present a new sensor technology that simplifies the brewing process from mashing to filling. 
The webinar will also shed light on how the combination of color and turbidity measurement with scattered light at 25° and 90° has a positive influence on mashing, fermentation and filtration. And how transmitted light and reflection sensors optimize phase changes and enable product recognition.
Oxygen measurement along the process helps to detect faults in the system, enabling timely actions before out-of-spec oxygen causes lasting damage to your product.
The large number of measuring points in breweries requires a smart concept for the verification and calibration of in-line dissolved oxygen sensors. A solution for these tasks will also be presented.
<blockquote>
Presenter: Holger Schmidt (Mettler Toledo)
</blockquote>
<blockquote>
Holger Schmidt backs up his practical know how as brewer and malster with a brewmaster degree from TUM Weihenstephan. For two decades he has been globally mediating the triangle between Food and Beverage producers, plant and machine builders, and automation companies, with a focus on hygienic sensor technologies.
</blockquote>

Mettler-Toledo: In-line Quality Control in Breweries

In-line Quality Control in Breweries

In-line measurement of relevant parameters helps to drive processes closer to their optimum.

Modern titration offers a simple, yet highly accurate method to ensure the quality and safety of many products we consume daily. While not a complicated technique, there are some subtleties that can ensure your titration results are accurate. Simple electrode care and optimization of basic titration parameters are crucial to helping you obtain results you can trust.
During this webinar, Sagar Irrinki, Quality Control Manager at Coastal Gulf &amp; International, Inc. will share how his laboratory navigates executing these tests on various types of titration applications. and how to overcome challenges with helpful titration tips. Eduardo Simoes, Product Specialist for Titration at Metrohm USA, will provide guidance for electrode selection and best practices for electrode care and maintenance. Don’t miss the live Q&amp;A at the end to get all your questions answered by Sagar and Eduardo. 
<h5>Key Learning Objectives:</h5>
<ul>
<li>Understand potentiometric electrode care and maintenance </li>
<li>Learn how to overcome titration challenges with useful tips</li>
<li>Receive simple guidelines to remove doubt from titration results </li>
<li>Learn how to select the appropriate electrode for your titration</li>
</ul>
<h5>Who Should Attend:</h5>
<ul>
<li>Anyone who wants to learn more about electrode care and maintenance</li>
<li>People interested in improving the consistency of their titration results</li>
<li>Anyone who needs a refresher on titration best practices</li>
<li>Chemists who want simple tips to improve confidence in titration analysis</li>
</ul>
<blockquote>
Presenter: Eduardo Simoes (Titration Product Specialist, Metrohm USA)
</blockquote>
<blockquote>
Presenter: Sagar Irrinki (Quality Control Manager, Coastal Gulf &amp; International, Inc.)
</blockquote>
<blockquote>
Presenter: Melissa O&#39;Meara (Forensic Science Consultant, C&amp;EN Media Group)
</blockquote>

Mastering Potentiometric Titration through Effective Electrode Selection and Method Optimization

Simple electrode care and how to overcome challenges with helpful titration tips.

Mastering Potentiometric Titration

<h3>MS School – Fundamentals of Mass Spectrometry Part 2</h3>
Mass spectrometry is a powerful analytical technique used to provide valuable information about the composition and structure of molecules. Understanding the fundamentals will empower you to make informed decisions about adding mass spectrometry to your laboratory analyses or maximizing the potential of your current MS systems.
In this educational webinar series, each session will cover a different aspect of mass spectrometry:
Part Two: Mass analyzers and detectors:
This session will look at the essential components of an MS system – the analyzer and the detector, focusing on quadrupole and time-of-flight systems. As well as showing how they operate, the session will outline the various types of experiments that can be run of each type of mass spectrometer.
<blockquote>
Presenter: Kieron Faherty, Ph.D. (Separations and Mass Spectrometry Field Marketing Manager, Waters Corporation)
</blockquote>
<blockquote>
Kieron Faherty is the Separations and Mass Spectrometry Field Marketing Manager for the Americas at Waters Corporation. He received his B.Sc. (Hons) in Chemistry from the University of Reading (Reading, Berkshire, UK) and his doctorate in Chemistry from the University of Massachusetts (Amherst, MA). He has held several field-based positions during his twenty-plus years at Waters, from Field Service Engineer on both quadrupole and Time-of-Flight MS systems to Principal Field Applications Specialist focused on biopharmaceutical applications.
</blockquote>

Waters Corporation: MS School – Fundamentals of Mass Spectrometry Series

Mass analyzers and detectors

This session will look at the essential components of an MS system – the analyzer and the detector, focusing on quadrupole and time-of-flight system.

The Right Laboratory Balance Service at the Right Time
Event Program:
<ul>
<li>Selection of the right instrument for your application</li>
<li>Installation and qualification</li>
<li>Preventive maintenance</li>
<li>Calibration</li>
<li>Routine testing</li>
<li>Replacement</li>
</ul>
Weighing is a core process in almost every application in a lab. To maintain consistent results, it&#39;s essential to regularly service your equipment. But what are the most important services, and how often do they need to be performed?
In this webinar, we will guide you, based on the lifecycle of a balance, through the different services that can help you to keep your instrument accurate and extend its lifetime – from the instrument selection to its installation, throughout its routine operation, and up to the time for replacement.
Join our live webinar with METTLER TOLEDO experts to gain a better understanding.
<blockquote>
Presenter: Simona Venzin (Head of Service Product Management, METTLER TOLEDO)
</blockquote>
<blockquote>
Presenter: Walter Krebs (Head of GWP Product Management, METTLER TOLEDO)
</blockquote>

Mettler-Toledo: Service Balances the Smart Way

Service Balances the Smart Way

A guide through different services that can help you to keep your instrument accurate and extend its lifetime.

With the latest regulatory updates encompassing a pragmatic and structural related approach to determining the risk of N-nitrosamine impurities in pharmaceuticals, there remains the ongoing need for pharmaceutical manufacturers to consistently mitigate and control levels of these impurities in new and existing products. When required, analytical testing plays an important role in ensuring levels remain below regulatory acceptance thresholds.
In this webinar, Marian Twohig, Ph.D, Principal Scientist at Waters Corporation, will provide an overview of the more recent progress around N-nitrosamines regulations. Driven by the latest regulatory guidelines, Marian will share a comprehensive overview of the development of an analytical methodology for the quantification of N-nitroso propranolol in propranolol, citing unexpected challenges and the resolutions that lead to robust method optimization beyond regulatory required thresholds.
Key learning objectives:
<ul>
<li>Align analytical method optimization to current regulatory guidance.</li>
<li>The importance of high-quality chromatographic methods to facilitate ease of API and isomeric impurity resolution.</li>
<li>Accessible approaches in tandem quadrupole mass spectrometry solutions supporting the investigation and tentative identification of unexpected peaks and other method optimization challenges.</li>
</ul>
Who should attend?
Those working in pharmaceutical analytical development, pharmaceutical QA/QC, and regulatory in innovative and generic pharma, contract testing, and research and manufacturing organizations (CTO, CRO, CDMO).
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
<blockquote>
Presenter: Dr. Marian Twohig (Principal Scientist, Waters Corporation)
</blockquote>
<blockquote>
Marian Twohig is a scientist with a passion for problem solving using analytical instrumentation. She has over 18 years of experience supporting quantitative and qualitative applications in the pharmaceutical, food and environmental and materials science industries. She works as a Principal Scientist for Waters Corporation where she has previously held several Senior Scientist positions.
</blockquote>

Waters Corporation: Managing the complexities of NDSRI method development: The N-nitroso propranolol case story

Managing the complexities of NDSRI method development: The N-nitroso propranolol case story

Overview of the development of an analytical methodology for the quantification of N-nitroso propranolol in propranolol.