Meeting EU Drinking Water Standards: The Critical Role of Sample Prep in Trace Contaminant Analysis

<p><strong>Although modern agriculture needs to be based on accurate real-time data on soil, plant, and environmental conditions, affordable, sufficiently sensitive, and robust monitoring devices for this purpose are currently missing. According to scientists, low-cost sensors based on new smart materials and printing technologies offer a suitable solution. The results of multidisciplinary research thus far and proposals for the development of these devices have been presented by researchers from Czechia, Great Britain, Spain, and the USA in a review article in the prestigious journal </strong><a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-68778-6#Abs1"><i><strong>Nature Communications</strong></i></a><strong>.</strong></p><p>“<i>Sensor technologies for monitoring plant health are still in their infancy. Only simple sensors capable of monitoring basic parameters such as pH, soil moisture, or temperature are commonly available on the market. However, if farmers are to face current challenges, including climate change, and ensure sufficient food for humanity, they need much more effective tools that will enable them to monitor, for example, various pathogens, including bacteria and fungi. In our opinion, a suitable solution is a combination of new smart materials and printing for the production of inexpensive, durable, and scalable materials</i>,” said the article’s first author, <strong>David Panáček</strong> from CATRIN, who worked on the study during his internship at Imperial College London.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg" alt="CATRIN: David Panáček" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg 208w," sizes="100vw" width="1536" height="1152"></p><p>Sensors for monitoring plant health, for example, lag behind similar devices used in human medicine. According to the authors, advances in materials science, which will enable the development of scalable sensor technologies, play a key role in this potential shift. “<i>Printing techniques, including inkjet printing, screen printing, aerosol printing, 3D printing, and direct laser writing, offer flexible ways to produce flexible sensors, large-area sensors, and sensors integrated directly into plants. The review article summarizes recent advances in printable low-dimensional materials for agricultural sensors, analyzes their physico-chemical properties in relation to sensor performance, and discusses key challenges and future opportunities requiring interdisciplinary integration</i>,” said one of the corresponding authors, <strong>Michal Otyepka</strong>.</p><p>The research brought together materials scientists, chemists, biologists, sensing experts, and printing technology specialists. Materials research and the use of graphene-based smart materials were led by scientists from CATRIN at Palacký University and VŠB-Technical University of Ostrava. Plant biologists from CATRIN contributed their knowledge of plant development, their responses to stress conditions, and the monitoring of their properties. Researchers from Imperial College London took care of the electronics, while representatives from<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/36"><strong> CEITEC – VUT</strong></a> focused on printing technologies. The team also included leading experts in sensing from the Catalan Institute of Nanoscience and Nanotechnology in Barcelona, and Joseph Wang of the University of California San Diego, the “father of sensing and electrochemistry,” also contributed his extensive knowledge.</p><p>“<i>This is a groundbreaking study on this topic, which has managed to attract some truly big names in their respective fields. Last but not least, the study demonstrates that interdisciplinarity at CATRIN gives rise to completely new and promising research topics, such as plant sensing and its use for studying plant-environment interactions and smart agriculture,</i>” added another corresponding author, <strong>Nuria De Diego</strong>.</p>

Current sensors are not good enough. Scientists propose a new way to monitor plant health

<p><strong>In this episode of the Concentrating on Chromatography podcast, host David Oliva interviews Ainslie Chen about her cutting-edge research on hemoglobin variant testing using liquid chromatography-high resolution mass spectrometry (LC-HR-MS). Ainslie discusses her novel method for separating and identifying hemoglobin subunits with mass shifts less than 1 Da, overcoming critical limitations in conventional clinical assays.</strong></p><p>Hear firsthand how her team developed an LC-HR-MS workflow using a C4 reversed-phase column, tackled technical challenges (including why C18 columns fell short), and achieved unprecedented sensitivity for variant detection in both adult and neonatal samples. The conversation touches on the potential of mass spectrometry to revolutionize clinical diagnostics, the importance of reproducibility, barriers to adoption in routine labs, and how teamwork drives scientific innovation.</p><p>Perfect for analytical chemists, clinical laboratorians, and anyone interested in the future of protein variant analysis, this episode also features Ainslie’s advice for early-career scientists and insights from her first ACS poster presentation.</p><h4><strong>Key Highlights:</strong></h4><ul><li>Motivation behind improving hemoglobinopathy testing &nbsp;</li><li>Technical advantages of LC-HR-MS over gene sequencing and CE &nbsp;</li><li>The crucial role of the C4 column in resolving challenging samples &nbsp;</li><li>Critical parameters for reproducible LC-HR-MS workflows &nbsp;</li><li>Barriers and outlook for clinical adoption of advanced mass spectrometry &nbsp;</li><li>The value of teamwork and mentorship in scientific research &nbsp;</li><li>Direct insights from recent ACS conference experiences</li></ul><h3><strong>Video transcription</strong></h3><p>In this interview, <strong>Ainslie Chen</strong> discusses her research on improving the detection and identification of hemoglobin variants using <strong>liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS)</strong>. The work addresses limitations of conventional hemoglobinopathy testing, which often struggles to resolve very small mass differences between closely related hemoglobin subunits. Because even a single amino-acid substitution can significantly alter hemoglobin structure and function, high analytical resolution is essential for accurate diagnosis of conditions such as anemia and sickle cell disease.</p><p>Chen explains why her team selected LC-HRMS over established clinical techniques like <strong>capillary electrophoresis</strong> and <strong>gene sequencing</strong>. While sequencing offers excellent accuracy, it is time-consuming, costly, and requires extensive sample preparation, making it impractical for routine clinical workflows. Capillary electrophoresis enables subunit separation but lacks the resolving power needed to distinguish variants differing by less than one Dalton. In contrast, high-resolution mass spectrometry provides both structural specificity and sensitivity, enabling confident identification of subtle hemoglobin variants with minimal sample preparation.</p><p>A key methodological insight from the project was the use of a <strong>C4 reversed-phase LC column</strong> instead of the more common C18 column. Chen describes how the shorter carbon chain and larger pore size of C4 columns improved protein elution and reduced denaturation, leading to more reproducible separations. Critical parameters for reproducibility included consistent mobile-phase composition (0.1% formic acid in water and acetonitrile), controlled temperature (60 °C for LC, ~320 °C capillary temperature), and stable chromatographic conditions.</p><p>Beyond hemoglobin analysis, Chen highlights the broader potential of high-resolution mass spectrometry in <strong>proteoform analysis</strong> and clinical diagnostics, including emerging applications in cancer detection. She acknowledges current barriers to clinical adoption—such as energy demands and instrument infrastructure—but points to advances like <strong>miniaturized mass spectrometers</strong> as promising steps toward wider use. The interview concludes with advice for young scientists: don’t hesitate to reach out to mentors, embrace collaboration, and view analytical chemistry as a versatile tool that bridges medicine, biology, environmental science, and beyond.</p><blockquote><p><strong>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</strong></p></blockquote><blockquote><h4><strong>Concentrating on Chromatography Podcast</strong></h4><p>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!</p><p>You can find <strong>Concentrating on Chromatography Podcast </strong>in podcast apps:</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL"><strong>Spotify</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185"><strong>Apple podcast</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography"><strong>podscan</strong></a></li></ul><p>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos"><strong>YouTube channel</strong></a></p></blockquote>

Unlocking Hemoglobin Variant Detection: LC-HR-MS Breakthrough with Ainslie Chen

Article

Video

Environment

Scientific article

Interview

Science and research

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

CATRIN

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Metrohm

Mettler-Toledo

Agilent Technologies

Technology Networks

Thermo Fisher Scientific

SelectScience

Waters Corporation

<p><strong>UV-VIS-NIR can be a powerful analysis technique in battery research and development. Whether it is studying new materials, monitoring electrolytes for degradation, or conducting measurements in situ using fiber optics, UV-VIS-NIR measurement capability can support applications from production to end-of-life recycling.</strong></p><p>Agilent's portfolio of instruments offers the high performance and flexible accessories needed for pioneering new applications.</p><blockquote><p><strong>Presenter:</strong> Scott Melis, PhD (Application Scientist, Agilent Technologies, Inc.)</p><p>Scott Melis has a PHD in Physics from Georgetown University in Washington, DC and started with Agilent in 2021 as a Molecular Spectroscopy Application Scientist. In his graduate work, Scott studied nanoparticle formation and growth for a variety of applications. Projects that he worked with include developing processes to deposit and characterize semiconducting molecular nano-cocrystals for use in optoelectronic devices as well as controlling polymer nanoparticle size through rapid mixing conditions.</p></blockquote>

Agilent Technologies: UV-VIS-NIR in Battery Development

UV-VIS-NIR in Battery Development

Agilent's portfolio of instruments offers the high performance and flexible accessories needed for pioneering new applications.

<header><p><strong>Join Us for an Engaging Live Webinar on Integrating UV/Vis Spectroscopy Into Your Laboratory Workflows</strong></p></header><main><div><div><p><strong>Program&nbsp;</strong></p><ul><li>Introduction to UV/Vis Spectroscopy</li><li>The Power of Integration</li><li>Live Demonstration</li><li>Customer Use Cases</li><li>Engage &amp; Discuss</li></ul></div></div><div><div><p>Discover how connecting your UV/Vis spectrophotometer with instruments like balances can transform your laboratory processes. By transmitting dissolution data directly to the spectrophotometer, you can streamline workflows and enhance data quality, leading to improved productivity and accuracy.</p></div></div><div><div><div><p>In this informative session, we’ll showcase the power of instrument integration and how it can revolutionize your daily routines. Using real-world case studies from various industries, including battery manufacturing, pharmaceuticals, and food and beverage, you’ll gain valuable insights into optimizing your laboratory workflows.</p><p><strong>Program Highlights</strong></p><ul><li><strong>Introduction to UV/Vis Spectroscopy</strong><br>Understand the basics and applications of UV/Vis spectroscopy in laboratories.</li><li><strong>The Power of Integration</strong><br>Explore the benefits of connecting your UV/Vis spectrophotometer with balances and other instruments.</li><li><strong>Live Demonstration</strong><br>Witness a live demonstration of data transmission from a balance to a UV/Vis spectrophotometer.</li><li><strong>Customer Use Cases</strong><br>Learn about integrated processes used in the battery, pharma, and food &amp; beverage industries.</li><li><strong>Engage &amp; Discuss</strong><br>Participate in a Q&amp;A session where we address your questions and discuss potential applications in your own lab.</li></ul><p>Don’t miss this opportunity to explore innovative solutions that can help you think critically about your own processes and enhance your laboratory's efficiency!</p></div></div></div></main><div><div><p><strong>Target Audience</strong></p><div><p>This webinar is designed for laboratory professionals, scientists, and managers across various industries, including:</p><ul><li>Pharmaceuticals: Quality control and research &amp; development teams looking to improve analytical processes</li><li>Food &amp; Beverage: Quality assurance and product development personnel aiming to enhance product testing efficiency</li><li>Battery Manufacturing: Engineers and technicians interested in optimizing material testing workflows</li><li>Laboratory Managers: Professionals seeking to streamline operations and improve data quality through instrument integration</li></ul><p>Whether you are just starting with UV/Vis spectroscopy or looking to enhance your existing laboratory workflows, this webinar is perfect for you. Register now to secure your spot and take the first step towards a more efficient laboratory.</p><ul><li><span style="padding-right:0px;" id="webinar-session-1"><strong>1. 10. 2025 9:00,&nbsp; English&nbsp;</strong></span><span id="webinar-session-2"><strong><svg width="16" height="16" viewBox="0 0 16 16" fill="none" xmlns="http://www.w3.org/2000/svg"></svg></strong></span></li><li><span id="webinar-session-2"><strong>1. 10. 2025 17:00,&nbsp; English&nbsp;</strong></span></li></ul><blockquote><p><span id="webinar-session-2"><strong>Presenter: </strong></span>Anika Adams (Product Manager, SPG UV/VIS)</p><div><p>Anika Adams is Product Manager for UV/Vis Spectrophotometers at METTLER TOLEDO, where she focuses on driving innovation and optimizing customer workflows. With a degree in business administration and experience spanning software development, mechanical engineering, and production, Anika brings a multidisciplinary perspective to the laboratory business. Her expertise lies in automating and enhancing customer processes, ensuring both product excellence and customer satisfaction.</p><p><strong>Presenter:</strong> Dr. Fabian Müller (Product Manager, SPG UV/VIS)</p><div><div><div><div><p>Dr. Fabian Müller, Ph.D., is an accomplished chemist from the ETH Zürich in Switzerland. After completing his doctoral studies, Dr. Müller joined the team at METTLER TOLEDO as an Application Specialist for UV/Vis spectroscopy, where he quickly established himself as a skilled and knowledgeable professional. His expertise in this area led to his promotion to the position of Product Manager for UV/Vis spectrophotometers.</p></div></div></div></div></div></blockquote></div></div></div>

Mettler Toledo: UV/Vis Integration in Laboratory Workflows 

UV/Vis Integration in Laboratory Workflows 

Join Us for an Engaging Live Webinar on Integrating UV/Vis Spectroscopy Into Your Laboratory Workflows

<div><p><strong>Join us for the last 5 series on building the perfect method for light scattering analysis.</strong></p><p><strong>Learn advanced tools and techniques to master ASTRA software, from normalization to DLS with flowing systems.</strong></p><h4><strong>Session Overview:</strong></h4><ul><li><h5><strong>Part 6 of 10: Building the Perfect Method - Normalization, Alignment, &amp; Inter-Detector Band Broadening Corrections</strong></h5><ul><li>Friday, September 26</li></ul></li><li><strong>Part 7 of 10: </strong>Navigating Sample Parameters – A Close Look at dn/dc and Extinction Coefficients<ul><li>Friday, October 3</li></ul></li><li><strong>Part 8 of 10: </strong>Advanced Characterization Tools for Multi-Component Analytes - Protein Conjugates, AAV, LNP and ADC<ul><li>Friday, October 10</li></ul></li><li><strong>Part 9 of 10: </strong>ASTRA for Particles: When and How to Deploy<ul><li>Friday, October 17</li></ul></li><li><strong>Part 10 of 10: </strong>DLS with Flowing Systems – Leveraging Rh and the Burchard-Stockmayer Plot in ASTRA<ul><li>Friday, October 24</li></ul></li></ul><h4><strong>Why Attend:</strong></h4><ul><li>Deepen your understanding of light scattering and ASTRA.</li><li>Gain actionable insights for your lab.</li><li>Interact with our expert, Dr. Andy Meyer.</li></ul><p>The live interactive web series are 100% live sessions, with anonymous Q&amp;A welcome during and after the discussion. Free for all Wyatt customers.</p><blockquote><p><strong>Hosted by:</strong> Dr. Andy Meyer</p><p>Dr. Andy Meyer joined Wyatt Technology in 2001, serving for several years as an Applications Scientist, then as Dean of Wyatt's "Light Scattering University" and as Director of Customer Service &amp; Support. After managing multiple regions in North America, Dr. Meyer is now a Principal Trainer for Waters | Wyatt Technology. As a Wyatt customer, he completed his Ph.D. in Applied Science – Polymer Chemistry from the College of William and Mary in Virginia.</p></blockquote></div>

Waters Corporation: Becoming an ASTRA Expert

Becoming an ASTRA Expert: Part 6

Learn essential method setup steps in ASTRA: normalization, alignment, and band broadening corrections for optimal accuracy in light scattering experiments.

<div><p><strong>Analytical methods are essential to ensuring pharmaceutical product quality, regulatory compliance, and patient safety. However, their reliability and reproducibility can be compromised by multiple sources of variability—including reagent quality, instrument performance, operator technique, sample preparation, and data processing. Understanding and controlling these sources is critical, especially when justifying post-approval changes to validated methods.</strong></p><p>This three-part webinar series features expert Peter Baker (Live Oak QA, Austin, Texas) and focuses on the importance of identifying, monitoring, and documenting variability within analytical workflows. Through open discussion and real-world insights, participants will gain a deeper understanding of how to build a scientifically sound case for method adjustments while maintaining regulatory compliance. Each session includes a live Q&amp;A to encourage interaction and address specific challenges.</p><h4><strong>Session 3: Analytical Control in Action – Real-World Case Studies</strong></h4><p>The final session presents real-world examples of method variability and how companies have successfully justified changes due to shifts in materials, instruments, or processes. Emphasis will be placed on documentation, regulatory communication, and lessons learned.</p><p><i><strong>Goal: </strong>Apply insights from case studies to your own workflows and gain practical strategies for managing change.</i><br>&nbsp;</p><blockquote><p><strong>Presenter:</strong> Peter Baker (President, Live Oak Quality Assurance LLC)</p><p>Peter E. Baker, President, Live Oak Quality Assurance LLC, has been consulting nationally and internationally since April 2019. Prior to consulting, Peter spent 11 years as a U.S. FDA Drug Investigator, with most of those years spent working in FDA’s overseas offices located in India, China and Chile. Peter was named FDA Investigator of the Year in 2013 for his work uncovering serious breaches in data integrity and has special interest in data governance and compliance with 21 CFR Part 11. Live Oak focuses on training and employee empowerment in critical thinking, with the goal of improving the quality of medicines through good data management.</p><p><strong>Presenter: </strong>Dr. Stephanie Harden (Senior Manager, Small Molecule Core Solutions – LC-MS, Waters Corporation)</p><p>Stephanie Harden, Senior Manager at Waters Corporation, leads the Product Marketing and Scientific teams for Waters small molecule HPLC portfolio. With over 25 years of experience in product and segment marketing, she has a proven track record in strategic program development, cross-functional leadership, and market-driven innovation. Her work connects scientific insight with commercial strategy to drive customer-focused solutions and sustained business growth. Stephanie holds a PhD in Chemistry from the University of Bristol, UK, and is a widely cited author.</p></blockquote></div>

Waters Corporation: Managing Method Variability: A Foundation for Risk-Based Change

Managing Method Variability: A Foundation for Risk-Based Change - Session 3

Discover real case studies on managing analytical variability, documenting changes, and maintaining compliance in pharma workflows.

Analytical Control in Action – Real-World Case Studies

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Biopharmaceuticals based on monoclonal antibodies, lipid nanoparticle-encapsulated mRNA, and transgene-carrying viral vectors, are significantly larger than traditional small-molecule drugs. This size difference requires specialized analytical tools. Size-exclusion chromatography (SEC) is particularly effective for studying proteins and has recently been adapted to analyze complex macromolecular assemblies like mRNA and DNA.</strong></p><p>Join us for this exciting two-part webinar series where Dr. Jelle De Vos from RIC group and Dr. Sonja Schneider from Agilent Technologies will discuss how SEC is evolving to meet the demands of modern biopharma. In Part 2, our experts will share real-world application examples of SEC with light scattering detection, highlighting how this powerful combination is transforming the analysis of complex biopharmaceuticals.</p><h5><strong>Key learning objectives of Part 2:</strong></h5><ul><li>Understand the practical application of SEC for the characterization of:<ul><li>monoclonal antibodies</li><li>mRNA-lipid nanoparticle formulations</li><li>adeno-associated viruses (AAVs)</li><li>virus-like particles (VLPs)</li></ul></li></ul><h5><strong>Who should attend?</strong></h5><ul><li>Scientists and researchers in biotherapeutics R&amp;D using SEC/light scattering.</li><li>Lab and quality leaders, including lab managers, directors, and QA/QC professionals in biopharma production.</li></ul><h5><strong>Want to go back and watch Part 1?</strong></h5><p><strong>Click here to register for Part 1</strong>, and hear the fundamentals of SEC and discover how coupling it with light scattering detection can advance the characterization and development of biopharmaceuticals.</p><h5><strong>Certificate of attendance</strong></h5><ul><li>If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.</li><li>If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Jelle De Vos (Senior Scientist, RIC group)</p><p>Dr. Jelle De Vos currently works at the RIC group as an expert in developing chromatography methodologies for analyzing complex biopharmaceutical samples. His work focuses on pushing the boundaries of modern separation science, and he has published over 40 articles on advancing the limits of ultra high-performance liquid chromatography and developing microfluidic technology.</p><p><strong>Presenter:&nbsp;</strong>Dr. Sonja Schneider (Scientist, Application Development, Agilent Technologies)</p><p>Dr. Sonja Schneider is an Application Scientist at Agilent Technologies in Waldbronn, Germany, who has published numerous application notes on the analysis of biopharmaceuticals. After obtaining her PhD in proteomics in 2011, she started as an Application Scientist for Bioanalytics and has been working various kinds of critical quality attributes of monoclonal antibodies, mRNA, and LNPs.&nbsp;</p><p><strong>Moderator:</strong> Olivia Long (Editorial Team, SelectScience)</p></blockquote></div></div></div>

SelectScience: Part 2: Size exclusion chromatography with light scattering for biopharmaceuticals

Part 2: Size exclusion chromatography with light scattering for biopharmaceuticals

Explore real-world SEC with light scattering for antibodies, mRNA-LNPs, AAVs, and VLPs. Insights from Agilent and RIC group experts.

SEC with light scattering for biopharmaceuticals

<p><strong>Dr. Michaela Nebel, Product Manager at Sensolytics GmbH, gives an overview of the theory of localized electrochemical techniques with a focus on Scanning Electrochemical Microscopy (SECM), Scanning Droplet Cell technique (SDC), and Scanning Electrochemical Cell Microscopy (SECCM). Then, application examples from different fields in electrochemistry, including electrocatalysis, corrosion research, and sensors are highlighted.</strong></p><p>In recent years, the rising inclusion of localized electrochemical analysis into classical electrochemical methods has allowed for more comprehensive characterization of sample surfaces from various fields of application.</p><h5><strong>Key learnings of this webinar:</strong></h5><ul><li><strong>Theoretical background of localized electrochemical techniques</strong> with a focus on Scanning Electrochemical Microscopy (SECM), Scanning Droplet Cell technique (SDC), and Scanning Electrochemical Cell Microscopy (SECCM)</li><li><strong>Guidelines for the selection</strong> of a localized technique fitting your individual research application</li><li><strong>Practical considerations</strong> for the use of the respective analysis method</li><li><strong>Selected applications</strong> from different fields of research, including electrocatalysis, corrosion research, and sensors</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Michaela Nebel (Product Manager at Sensolytics GmbH)</p></blockquote>

Metrohm: Introduction to Localized Electrochemical Techniques

Introduction to Localized Electrochemical Techniques

Learn SECM, SDC, and SECCM fundamentals and applications in electrocatalysis, corrosion research, and sensors. Practical guidance from experts.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p>Join us for an insightful webinar exploring the Lab of the Future, where emerging technologies like AI, automation and smart lab environments are revolutionizing scientific research. Discover how innovations in lab informatics, robotics and real-time data integration are driving enhanced research efficiency, fostering collaboration and ensuring data integrity. This event is designed for scientists, lab managers and technology leaders eager to learn about the next generation of research spaces and how to harness these advancements for breakthrough discoveries.</p><h5><strong>Attend this webinar to:</strong></h5><ul><li>See how AI and automation boost lab efficiency</li><li>Understand smarter data management with lab informatics</li><li>Discover robotics’ role in accelerating research</li><li>Learn the impact of real-time data integration</li><li>Explore building future-ready smart labs</li></ul><blockquote><p><strong>Presenter: </strong>Nick Birse, PhD (Lecturer, Institute for Global Food Security, Queen's University Belfast)</p><p><strong>Presenter:&nbsp;</strong>Dagnachew (Dan) Birru, PhD (Global Head of Research and Development, Quantiphi)</p><p><strong>Presenter:&nbsp;</strong>Vishal Vaddina (Principal Architect – R&amp;D, Quantiphi)</p><p><strong>Presenter:&nbsp;</strong>Robyn Stoller (Business Development Manager, Cytiva)</p></blockquote></div></div></div>

Technology Networks: Tech Spotlight: Lab of the Future 2025

Tech Spotlight: Lab of the Future 2025

Discover innovations in AI, automation, robotics, and informatics transforming labs into future-ready environments for efficient, collaborative research.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Prof. Thalassinos's research focuses on understanding how cells respond to DNA damage using single-cell proteomics. The study employs a compound called 60G to induce DNA damage, which activates DNA repair mechanisms such as mismatch repair, base excision repair, and nucleotide excision repair. By analyzing single cells, the research aims to uncover the variability in protein expression and the biological processes involved in DNA repair and apoptosis.</strong></p><p>The team uses advanced techniques like the Orbitrap Eclipse mass spectrometer and the SLN1 single-cell isolation system to isolate and analyze individual cells. This approach allows them to observe the upregulation of proteins involved in DNA repair and the arrest of cells in the S phase of the cell cycle. The findings highlight the importance of single-cell proteomics in revealing cellular heterogeneity and the dynamic response to DNA damage, which could have implications for understanding diseases like cancer and neurodegenerative disorders.&nbsp;</p><h5><strong>Learning points:</strong></h5><ul><li><strong>Single-Cell Proteomics Advantage: </strong>Single-cell proteomics allows for the observation of individual cellular responses to DNA damage, revealing heterogeneity that would be masked in bulk proteomics. This approach helps in understanding the specific activation of DNA repair mechanisms and cell cycle arrest at the S phase.&nbsp;</li><li><strong>DNA Repair Mechanisms: </strong>The study highlights the activation of various DNA repair pathways, such as mismatch repair, base excision repair, and nucleotide excision repair, in response to DNA damage induced by the compound 60G. This understanding is crucial for insights into diseases like cancer and neurodegenerative disorders.&nbsp;</li><li><strong>Technological Integration: </strong>The use of advanced technologies like the <strong>Orbitrap Eclipse</strong> mass spectrometer and the SLN1 single-cell isolation system enables precise isolation and analysis of single cells, facilitating detailed proteomic studies and enhancing the understanding of cellular processes at a granular level.&nbsp;</li></ul><h5><strong>Who should attend:</strong></h5><ul><li><strong>Cancer Researchers: </strong>Understanding the variability in DNA repair mechanisms at the single-cell level can provide insights into tumor heterogeneity and the development of targeted cancer therapies.</li><li><strong>Neurodegenerative Disease Scientists</strong>: Insights into DNA damage response mechanisms can aid in understanding the molecular basis of neurodegenerative diseases and potentially lead to new therapeutic strategies.&nbsp;</li><li><strong>Proteomics and Genomics Technologists:</strong> Professionals working with advanced proteomics and genomics technologies can benefit from the presentation's focus on cutting-edge techniques for single-cell analysis, enhancing their research capabilities and methodologies.&nbsp;</li></ul><p>If you cannot attend this webinar please register to receive a link to the On Demand version the following day.&nbsp;</p><blockquote><p><strong>Presenter: </strong>Prof. Konstantinos Thalassinos (Professor, University College London)</p><p>Kostas moved to the UK in 1998 to study for a BSc in Genetics at the University of Leicester, having completed his high school education in his native Greece. After graduation he went on to the University of York to undertake a Masters in Bioinformatics, which included a three-month industrial placement writing software to process mass spectrometric data. Having gained an interest in mass spectrometry, Kostas then went to the University of Warwick in order to pursue a PhD that combined experimental and computational studies in mass spectrometry-based proteomics. After being awarded his PhD in 2006, Kostas was the successful recipient of a one-year Wellcome Trust Value in People Fellowship. Post-doctoral training followed and in 2010 he moved to the Institute of Structural and Molecular Biology at University College London / Birkbeck to take up a lectureship in biophysical mass spectrometry and has been there ever since. In 2015 he was promoted to Senior Lecturer and in 2019 to Professor of mass spectrometry.</p><p>His lab is using structural mass spectrometry approaches, especially ion mobility and crosslinking, to study the structure and dynamics of proteins and protein complexes, particularly those involved in protein misfolding diseases.</p></blockquote></div></div></div>

Thermo Fisher Scientific: ASMS 2025 Workshops

Probing DNA-damage response at the single cell level

Explore single-cell proteomics in DNA damage research. See how Orbitrap Eclipse and SLN1 reveal repair mechanisms, cell cycle arrest, and disease insights.

<p><strong>New functions of the improved UV Workstation Software will be described and demonstrated.</strong></p><blockquote><p><strong>Presenter:&nbsp;</strong> Scott Melis, PhD (Application Scientist, Agilent Technologies, Inc.)</p><p>Scott Melis has a PHD in Physics from Georgetown University in Washington, DC and started with Agilent in 2021 as a Molecular Spectroscopy Application Scientist. In his graduate work, Scott studied nanoparticle formation and growth for a variety of applications. Projects that he worked with include developing processes to deposit and characterize semiconducting molecular nano-cocrystals for use in optoelectronic devices as well as controlling polymer nanoparticle size through rapid mixing conditions.</p></blockquote>

Agilent Technologies: New Software Features for UV Work Station Software

New Software Features for UV Work Station Software

New functions of the improved UV Workstation Software will be described and demonstrated.

<h4><strong>Our newest HPLC columns are game changing</strong></h4><h5><strong>Liquid chromatography is evolving</strong></h5><p>With growing demands for sensitivity, reproducibility, and speed, today’s workflows need column technology that can keep up. Whether you are analyzing trace-level compounds or navigating complex bioseparations, the right column makes all the difference.</p><p>A new generation of LC column technology is setting the bar higher—delivering cleaner separations, sharper peaks, faster equilibration, and more reliable results for even the most metal-sensitive analytes.</p><h5><strong>Want to see it in action?</strong></h5><p>Join our webinar to explore how this new column technology transforms oligonucleotide separations for characterization, sequencing, and impurity profiling.</p><blockquote><p><strong>Presenter:&nbsp;</strong> Dr. Anne Blackwell (Product Manager Bio LC Columns, Agilent Technologies)</p><p>Anne is a product manger for bio LC columns at Agilent, with previous experience as a product support scientist for bio LC columns and an LC/MS applications scientist focused on metabolomics. &nbsp;She has a Ph.D. in analytical chemistry from the University of Arizona where she studied mass spectrometry of non-covalent protein assemblies.</p><p><strong>Presenter: </strong>Dr. Andrew Coffey (Senior Application Scientist, Agilent Technologies)</p><p>Andrew Coffey joined Agilent Technologies Biocolumns Applications Team in 2011. &nbsp;He has over 35 years experience in method development, technical support and troubleshooting of reversed phase, ion exchange, size exclusion and many other liquid chromatographic techniques.</p></blockquote>

Agilent Technologies: Inert Separations for Oligo LC-MS Workflows

Inert Separations for Oligo LC-MS Workflows

Explore Agilent’s new HPLC columns in a webinar on advanced oligonucleotide separations, sequencing, and impurity profiling.